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Bollettino di zoologia Volume 59, 1992 - Issue 4
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Morphology & comparaitive physiology

Effects of diazepam on cellularization and nuclear migration in the early Drosophila embryo

Giuliano Callaini Dipartimento di Biologia Evolutiva, Università di Siena, via Mattioli 4, Siena, I‐53100, Italy
,
Romano Dallai Dipartimento di Biologia Evolutiva, Università di Siena, via Mattioli 4, Siena, I‐53100, Italy
&
Maria Giovanna Riparbelli Dipartimento di Biologia Evolutiva, Università di Siena, via Mattioli 4, Siena, I‐53100, Italy
Pages 395-399 | Received 17 Apr 1992, Accepted 11 May 1992, Published online: 28 Jan 2009
 
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Abstract

Drosophila embryos exposed to diazepam showed an abnormal centrosome function. Mitotic progression was altered and the migration of the nuclei towards the embryo surface was irregular. Cleavage furrow formation was also affected, large cortical areas failing to cellularize.

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