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Morphology & comparaitive physiology

Effects of diazepam on cellularization and nuclear migration in the early Drosophila embryo

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Pages 395-399 | Received 17 Apr 1992, Accepted 11 May 1992, Published online: 28 Jan 2009

References

  • Andersson , L. C. , Lehto , V.‐P. , Stenman , S. , Badley , R. A. and Virtanen , I. 1981 . Diazepam induces mitotic arrest at prometaphase by inhibiting centriolar separation. . Nature, Lond. , 291 : 247 – 248 .
  • Brinkley , B. R. 1985 . Microtubule organizing centres. . Ann. Rev. Cell Biol. , 1 : 145 – 172 .
  • Callaini , G. and Anselmi , F. 1988 . Centrosome splitting during nuclear elongation in the Drosophila embryo. . Exp. Cell Res. , 178 : 415 – 425 .
  • Callaini , G. , Dallai , R. and Riparbelli , M. G. 1989 . Diazepam induces abnormal mitotic spindles in early Drosophila embryos. . Biol. Cell. , 67 : 313 – 320 .
  • Callaini , G. and Riparbelli , M. G. 1990 . Centriole and centrosome cycle in the early Drosophila embryo. . J. Cell Sci. , 97 : 539 – 543 .
  • Campos‐Ortega , J. A. and Hartenstein , V. 1985 . The embryonic development of Drosophila melanogaster , Berlin : Springer‐Verlag .
  • Echalier , G. and Ohanessian , A. 1970 . In vitro culture of Drosophila melanogaster embryonic cells . 6 : 162 – 172 . In vitro
  • Euteneuer , U. and Schliwa , M. 1985 . Evidence for an involvement of ac‐tin in the positioning and motility of centrosomes. . J. Cell Biol. , 101 : 96 – 103 .
  • Foe , V. E. and Alberts , B. M. 1983 . Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis. . J. Cell Sci. , 61 : 31 – 70 .
  • Giloh , H. and Sedat , J. W. 1982 . Fluorescence microscopy: reduced photobleaching of rhodamine and fluorescein protein conjugates by n‐propyl gallate. . Science , 217 : 1252 – 1255 .
  • Gonzalez , C. , Casal , J. and Ripoll , P. 1988 . Functional monopolar spindles caused by mutation in mgr, a cell division gene of Drosophila melanogaster. . J. Cell Sci. , 89 : 39 – 47 .
  • Gonzalez , C. , Saunders , R. D. C. , Casal , J. , Molina , I. , Carmena , M. , Ripoll , P. and Glover , D. M. 1990 . Mutations at the asp locus of Drosophila lead to multiple free centrosomes in syncytial embryos, but restrict centrosome duplication in larval neuroblasts. . J. Cell Sci. , 96 : 605 – 616 .
  • Hsu , T. C. , Liang , J. C. and Shirley , L. R. 1983 . Aneuploidy induction by mitotic arrestants, effects of diazepam on diploid Chinese hamster cells. . Mutation Res. , 122 : 201 – 209 .
  • Huettner , A. F. 1933 . Continuity of the centrioles in Drosophila melanogaster. . Z. Zellforsch. Mikrosk. Anat. , 19 : 119 – 134 .
  • Karsenti , E. and Maro , B. 1986 . Centrosomes and the spatial distribution of microtubules in animal cells. . Trends Biochem. Sci , 11 : 460 – 463 .
  • Kiehart , D. P. , Ketchum , A. , Young , P. , Lutz , D. , Alfenito , M. R. , Chang , X‐J. , Awobuluyi , M. , Pesacreta , T. C. , Inoué , S. , Stewart , C. T. and Chen , T. L. 1990 . Contractile proteins in Drosophila development. . Ann. N. Y. Acad. Sci. , 583 : 233 – 251 .
  • Lafi , A. and Parry , J. M. 1988 . A study of the induction of aneuploidy and chromosome aberrations after diazepam, medazepam, midazolam and bromazepam treatment. . Mutagenesis , 3 : 23 – 27 .
  • Lafi , A. , Parry , E. M. and Parry , J. M. 1987 . The effects of benzodiazepines upon the fidelity of mitotic cell division in cultured Chinese hamster cells. . Mutation Res. , 189 : 319 – 322 .
  • Limbourg , B. and Zalokar , M. 1973 . Permeabilization of Drosophila eggs. . Dev. Biol. , 35 : 382 – 387 .
  • Marano , F. , Santa‐Maria , A. and Fries , W. 1984 . Effects of diazepam on mitosis and basal body duplication to synchronously dividing flagellate cells. . Biol. Cell , 50 : 163 – 172 .
  • Mazia , D. 1987 . The chromosome cycle and the centrosome cycle in the mitotic cycle . Int. Rev. Cytol. , 100 : 49 – 92 .
  • Paweletz , N. , Mazia , D. and Finze , E.‐M. 1987 . Fine structural studies of the bipolarization of the mitotic apparatus in the fertilized sea urchin egg. II. Bipolarization before the first mitosis. . Eur. J. Cell Biol. , 44 : 205 – 213 .
  • Planques , V. , Warn , A. and Warn , R. M. 1991 . The effects of microinjection of rhodaminc‐phalloidin on mitosis and cytokinesis in early stage Drosophila embryos. . Exp. Cell Res. , 192 : 557 – 566 .
  • Rattner , J. B. and Berns , M. W. 1976 . Centriolar behavior in early mitosis of rat kangaroo cells (PtK2). . Chromosoma , 54 : 387 – 395 .
  • Schatten , H. , Walter , M. , Biessmann , H. and Schatten , G. 1988 . Microtubules are required for centrosome expansion and positioning while microfilaments are required for centrosome separation in sea urchin eggs during fertilization and mitosis. . Cell Motil. Cytoskeleton , 11 : 248 – 259 .
  • Sullivan , W. , Minden , J. S. and Alberts , B. M. 1990 . daughterless‐abo‐like, a Drosophila maternal‐effect mutation that exhibits abnormal centrosome separation during the late blastoderm divisions. . Development , 110 : 311 – 323 .
  • Sunkel , C. E. and Glover , D. M. 1988 . polo, a mitotic mutant of Drosophila displaying abnormal spindle poles. . J. Cell Sci. , 89 : 25 – 38 .
  • Warn , R. M. and Magrath , R. 1983 . F‐actin distribution during the cellularization of the Drosophila embryo visualized with FL‐phalloidin. . Exp. Cell Res. , 143 : 103 – 114 .
  • Warn , R. M. and Warn , A. 1986 . Microtubule arrays present during the syncytial and cellular blastoderm stages of the early Drosophila embryo. . Exp. Cell Res. , 163 : 201 – 210 .
  • Warn , R. M. , Flegg , L. and Warn , A. 1987 . An investigation of microtubule organization and functions in living Drosophila embryos by injection of a fluorescently labeled antibody against tyrosinated a‐tubulin. . J. Cell Biol. , 105 : 1721 – 1730 .
  • Zalokar , M. and Erk , I. 1976 . Division and migration of nuclei during early embryogenesis of Drosophila melonogaster. . J. Microsc. Biol. Cell. , 25 : 97 – 106 .
  • Zalokar , M. and Erk , I. 1977 . Phase‐partition fixation and staining of Drosophila eggs. . Stain Technol. , 52 : 89 – 95 .

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