Correction

This article refers to:

A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

Article title: A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

Authors: Paul Arras, Han Byul Yoo, Lukas Pekar, Christian Schröter, Thomas Clarke, Simon Krah, Daniel Klewinghaus, Vanessa Siegmund, Andreas Evers, and Stefan Zielonk

Journal: MABS

Bibliometrics: Volume 15, Number 1, pages 1-19

DOI: https://doi.org/10.1080/19420862.2023.2261149

An error has been introduced in Table 4 in column SEC purity [%].

Table 4 Production yields and analytical purity of nominated sequences and their ability to function as NKCE with humanized cetuximab (ctx) on the GA chain, as indicated by the EC₅₀ for killing of target cells. Evaluation of AC- SINC is included for the one-armed constructs.

one armed (hu)VHH-SEEDbodies				VHH x Ctx SEEDbodies
ID	Yield o.a. [mg/L]	SEC Purity [%]	AC-SINS	SEC Purity [%]	EC50 [nM]
FERF.cluster1.4	193.2	100.0	0.1	93.0	no killing
FERF.cluster1.7	147.9	100.0	-0.2	95.7	no killing
WT.cluster1.3	122.3	100.0	-0.4	96.1	no killing
FERF.cluster2.15	183.2	100.0	0.0	97.6	0.05
WT.cluster2.13	146.8	100.0	-0.5	97.9	4.07
VGLW.cluster2.14	98.4	100.0	-0.3	97.1	no killing
FERF.cluster2.10	131.3	100.0	-0.5	96.0	0.06
FERF.cluster2.11	133.4	100.0	-0.4	94.6	0.05
WT.cluster5.25	193.0	100.0	-0.4	88.8	0.03
FERF.cluster5.26	221.1	97.6	-0.5	98.0	4.65

All molecules show sec purities around or above 90% except one molecule.

The corrected table is given below: