Abbreviations
acBSA | = | acetylated BSA |
A. fumigatus | = | Aspergillus fumigatus |
AIF | = | alkali-insoluble fraction |
BSA | = | bovine serum albumin |
CHO cells | = | Chinese hamster ovary cells |
CS | = | culture supernatant |
CM | = | complete medium |
FReDs | = | fibrinogen-related domains |
GlcNAc | = | N-acetylglucosamine |
IL-8 | = | interleukin 8 |
MASP-2 | = | MBL-associated serine protease 2 |
MBL | = | mannan-binding lectin |
ON | = | overnight |
rM-ficolin | = | recombinant M-ficolin |
RT | = | room temperature. |
S. typhimurium | = | Salmonella typhimurium |
TRIFMA | = | time-resolved fluorometry |
WGA | = | wheat germ agglutinin |
Disclosure of potential conflicts of interest
No potential conflicts of interest were disclosed.
Acknowledgments
Jensen-K, Lund-KP, Christensen-KB, Holm-AT, Jepsen-CS, Dubey-LK and Galgóczy-L performed experiments; Jensen-K, Lund-KP and Sorensen-GL wrote the manuscript; Moeller-JB, Schlosser-A, Thiel-S, Holmskov-U and Sorensen-GL designed experiments; Thiel-S and Sorensen-GL conceived study; all co-authors approved final version of the manuscript.
Funding
We would like to thank technician Lisbeth Jensen, Aarhus University, and Karen E. Olsen and Ole Nielsen, Department of Pathology, Odense University Hospital, for all of the help and support with providing and interpreting the immunohistochemical sections. L.G. was supported by a Lise Meitner fellowship (M1776-B20) from the Austrian Science Fund (FWF) and the Postdoctoral Excellence Program (PD 120808) of the Hungarian National Research, Development and Innovation Office (NKFI Office). The Danish Research Council for Independent Research further supported this study.