4,481
Views
15
CrossRef citations to date
0
Altmetric
Primary Research

Phytochemical analysis, antioxidant and antilipid peroxidation effects of a medicinal plant, Adhatoda vasica

, , &
Pages 305-312 | Received 27 Apr 2014, Accepted 23 Dec 2014, Published online: 30 Jan 2015
 

Abstract

Many diseases are associated with oxidative stress caused by reactive oxygen species and free radicals generated in living cells. This study deals with finding naturally occurring antioxidants of plant origin. The study investigated the phytochemistry, antioxidant and free radical scavenging potential of ethanolic leaf extract of Adhatoda vasica (ELEAV) using different antioxidant models. The phytochemical analysis of ELEAV revealed the presence of alkaloids, flavonoids, terpenoids, saponins, phenols and steroids. ELEAV also showed an antioxidant capacity, with inhibition of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical by 69.23%. ELEAV had potent inhibitory effects on scavenging nitric oxide, superoxide and hydroxyl radicals, by 65.24%, 61.54% and 61.24%, respectively. Moreover, ELEAV displayed a concentration-dependent reducing power activity and potent inhibitory effects on ferric ion-induced lipid peroxidation (68.26%) in bovine brain extract. These findings confirm the biological efficacy of A. vasica as a potential source of natural antioxidants.

Disclosure statement

No potential conflict of interest was reported by the authors.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.