Zinc Absorption & Homeostasis in the Human Body: A General Overview

ABSTRACT

Zinc is essential for the overall well-being of the human body due to its numerous structural, catalytic, and signalling functions. Therefore, maintaining a constant state of zinc homeostasis is crucial. The disturbances in zinc homeostasis are linked to numerous diseases and disorders, including metabolic syndrome and neurodegenerative diseases. In this review, we have discussed a general overview of zinc absorption and homeostasis, particularly the factors affecting zinc absorption and the body’s mechanisms to maintain zinc homeostasis at both the systemic and cellular levels.

KEYWORDS:

• Zinc
• absorption
• Antinutrients
• Homeostasis
• Zinc transporters

Acknowledgments

This work was supported by Science and Technology Innovation Talent Project of Sichuan Province (2022JDRC0039) and Chunhui Project of the Ministry of Education (HLJ2019005).

Disclosure statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Correction Statement

This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

The work was supported by the Science and Technology Innovation Talent Project of Sichuan Province [2022JDRC0039]; Chunhui Project of the Ministry of Education [HLJ2019005].