A Novel and Efficient Strategy for the Preparation of 2,4-Disubstituted-1,2,3-triazoles

Abstract

We have developed a novel and efficient method for the preparation of 2,4-disubstituted-1,2,3-triazoles. These compounds 3a–3p were synthesized in good yield by refluxing α-aminoacetophenones and hydrazines in glacial acetic acid. The reaction proceeds under mild conditions and is compatible with various functional groups.

Keywords:

• Synthesis
• 2,4-Disubstituted-1,2,3-triazoles