COMPARAISON DE TROIS APPROCHES POUR L’ESTIMATION DE L’INCERTITUDE

Abstract

Three different approaches for the estimation of uncertainty measurements using the same analytical method were compared, namely validation, robustness and inter-laboratory studies. The uncertainty obtained with the robustness study predicted well the uncertainty of the inter-laboratory study. On the other hand, the uncertainty estimation obtained with the validation study is lower than those obtained with the two other approaches but is still acceptable as long as the analytical method will be used in a single laboratory.

Keywords:

• Liquid Chromatography
• Validation
• Robustness
• Inter-laboratory study
• Uncertainty assessment.