Disclosure
Dr Igor Barjaktarevic reports grants from AMGEN and GE Healthcare, and personal fees from Astra Zeneca, Grifols, CSL Behring, Boehringer Ingelheim, Verona Pharama and Fisher and Paykel Healthcare, outside the submitted work. Professor Christopher Cooper reports he is employed part-time by the GlaxoSmithKline as a global medical expert with responsibilities for external scientific engagement and internal medical education. The authors report no other conflicts of interest in this work.