International Journal of Chronic Obstructive Pulmonary Disease, Volume 13, Issue (2018)

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International Journal of Chronic Obstructive Pulmonary Disease, Volume 13, Issue (2018)

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Original Research

Article
Anxiety and depression among dairy farmers: the impact of COPD
Alicia Guillien, Lucie Laurent, Thibaud Soumagne, Marc Puyraveau, Jean-Jacques Laplante, Pascal Andujar, Isabella Annesi-Maesano, Nicolas Roche, Bruno Degano & Jean-Charles Dalphin
Pages: 1-9
Published online: 19 Dec 2017
AbstractforAnxiety and depression among dairy farmers: the impact of COPD | Full Text | References | PDF (597.1 KB)
  • 119 Views
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Open Access
Article
Association of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD
Elise G De Smet, Leen JM Seys, Fien M Verhamme, Bart M Vanaudenaerde, Guy G Brusselle, Colin D Bingle & Ken R Bracke
Pages: 11-27
Published online: 19 Dec 2017
AbstractforAssociation of innate defense proteins BPIFA1 and BPIFB1 with disease severity in COPD | Full Text | References | PDF (10.1 MB)
  • 73 Views
  • 19 CrossRef citations
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Open Access
Article
Microbiological airway colonization in COPD patients with severe emphysema undergoing endoscopic lung volume reduction
Franziska C Trudzinski, Frederik Seiler, Heinrike Wilkens, Carlos Metz, Annegret Kamp, Robert Bals, Barbara Gärtner, Philipp M Lepper & Sören L Becker
Pages: 29-35
Published online: 19 Dec 2017
AbstractforMicrobiological airway colonization in COPD patients with severe emphysema undergoing endoscopic lung volume reduction | Full Text | References | PDF (297 KB)
  • 71 Views
  • 3 CrossRef citations
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Open Access
Article
Survival following pulmonary rehabilitation in patients with COPD: the effect of program completion and change in incremental shuttle walking test distance
Linzy Houchen-Wolloff, Johanna EA Williams, Ruth H Green, Gerrit Woltmann, Michael C Steiner, Louise Sewell, Michael DL Morgan & Sally J Singh
Pages: 37-44
Published online: 20 Dec 2017
AbstractforSurvival following pulmonary rehabilitation in patients with COPD: the effect of program completion and change in incremental shuttle walking test distance | Full Text | References | PDF (484.8 KB)
  • 145 Views
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Open Access

Review

Review Article
Inhaled therapies in patients with moderate COPD in clinical practice: current thinking
Amnon Ariel, Alan Altraja, Andrey Belevskiy, Piotr W Boros, Edvardas Danila, Matjaz Fležar, Vladimir Koblizek, Zvi G Fridlender, Kosta Kostov, Alvils Krams, Branislava Milenkovic, Attila Somfay, Ruzena Tkacova, Neven Tudoric, Ruxandra Ulmeanu & Arschang Valipour
Pages: 45-56
Published online: 21 Dec 2017
AbstractforInhaled therapies in patients with moderate COPD in clinical practice: current thinking | Full Text | References | PDF (403.9 KB)
  • 110 Views
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Open Access

Original Research

Article
Geographical distribution of COPD prevalence in Europe, estimated by an inverse distance weighting interpolation technique
Ignacio Blanco, Isidro Diego, Patricia Bueno, Eloy Fernández, Francisco Casas-Maldonado, Cristina Esquinas, Joan B Soriano & Marc Miravitlles
Pages: 57-67
Published online: 20 Oct 2022
AbstractforGeographical distribution of COPD prevalence in Europe, estimated by an inverse distance weighting interpolation technique | Full Text | References | PDF (4.8 MB)
  • 382 Views
  • 50 CrossRef citations
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Open Access
Article
The impact of indacaterol/glycopyrronium fixed-dose combination versus tiotropium monotherapy on lung function and treatment preference: a randomized crossover study – the FAVOR study
Peter Kardos & Ina Hagedorn-Peinz
Pages: 69-77
Published online: 22 Dec 2017
AbstractforThe impact of indacaterol/glycopyrronium fixed-dose combination versus tiotropium monotherapy on lung function and treatment preference: a randomized crossover study – the FAVOR study | Full Text | References | PDF (952.5 KB)
  • 59 Views
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Open Access
Article
Association between respiratory impedance measured by forced oscillation technique and exacerbations in patients with COPD
Hitomi Yamagami, Akihiko Tanaka, Yasunari Kishino, Hatsuko Mikuni, Tomoko Kawahara, Shin Ohta, Mayumi Yamamoto, Shintaro Suzuki, Tsukasa Ohnishi & Hironori Sagara
Pages: 79-89
Published online: 22 Dec 2017
AbstractforAssociation between respiratory impedance measured by forced oscillation technique and exacerbations in patients with COPD | Full Text | References | PDF (693.1 KB)
  • 85 Views
  • 7 CrossRef citations
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Open Access
Article
Cardiopulmonary exercise test and PaO2 in evaluation of pulmonary hypertension in COPD
Ingunn Skjørten, Janne Mykland Hilde, Morten Nissen Melsom, Jonny Hisdal, Viggo Hansteen, Kjetil Steine & Sjur Humerfelt
Pages: 91-100
Published online: 22 Dec 2017
AbstractforCardiopulmonary exercise test and PaO2 in evaluation of pulmonary hypertension in COPD | Full Text | References | PDF (2 MB)
  • 69 Views
  • 8 CrossRef citations
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Open Access
Article
Comparison of COPD Assessment Test and Clinical COPD Questionnaire to predict the risk of exacerbation
Yong Suk Jo, Ho Il Yoon, Deog Kyeom Kim, Chul-Gyu Yoo & Chang-Hoon Lee
Pages: 101-107
Published online: 20 Oct 2022
AbstractforComparison of COPD Assessment Test and Clinical COPD Questionnaire to predict the risk of exacerbation | Full Text | References | PDF (1.6 MB)
  • 137 Views
  • 14 CrossRef citations
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Open Access
Article
Examining 30-day COPD readmissions through the emergency department
Michael E Rezaee, Charlotte E Ward, Bonita Nuanez, Daniel A Rezaee, Jeffrey Ditkoff & Alexandra Halalau
Pages: 109-120
Published online: 27 Dec 2017
AbstractforExamining 30-day COPD readmissions through the emergency department | Full Text | References | PDF (397.1 KB)
  • 107 Views
  • 7 CrossRef citations
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Open Access
Article
Risk factors predict frequent hospitalization in patients with acute exacerbation of COPD
Xia Wei, Zhengquan Ma, Nan Yu, Jingting Ren, Chenwang Jin, Jiuyun Mi, Meijuan Shi, Libin Tian, Yanzhong Gao & Youmin Guo
Pages: 121-129
Published online: 27 Dec 2017
AbstractforRisk factors predict frequent hospitalization in patients with acute exacerbation of COPD | Full Text | References | PDF (1.9 MB)
  • 132 Views
  • 14 CrossRef citations
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Open Access
Article
Understanding of COPD among final-year medical students
Javier Mohigefer, Carmen Calero-Acuña, Eduardo Marquez-Martin, Francisco Ortega-Ruiz & Jose Luis Lopez-Campos
Pages: 131-139
Published online: 28 Dec 2017
AbstractforUnderstanding of COPD among final-year medical students | Full Text | References | PDF (428.5 KB)
  • 107 Views
  • 10 CrossRef citations
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Open Access
Article
Impact of acute exacerbations on platelet reactivity in chronic obstructive pulmonary disease patients
Mariana Muñoz-Esquerre, José Luis Ferreiro, Daniel Huertas, Ana Lucrecia Marcano, Marta López-Sánchez, Gerard Roura, Joan Antoni Gómez-Hospital, Jordi Dorca, Angel Cequier & Salud Santos
Pages: 141-148
Published online: 20 Oct 2022
AbstractforImpact of acute exacerbations on platelet reactivity in chronic obstructive pulmonary disease patients | Full Text | References | PDF (663 KB)
  • 71 Views
  • 7 CrossRef citations
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Open Access
Article
Exposure to environmental tobacco smoke from husband more strongly impacts on the airway obstruction of nonsmoking women
Kazuaki Suyama, Ryo Kozu, Takako Tanaka, Yuji Ishimatsu & Terumitsu Sawai
Pages: 149-155
Published online: 28 Dec 2017
AbstractforExposure to environmental tobacco smoke from husband more strongly impacts on the airway obstruction of nonsmoking women | Full Text | References | PDF (381.1 KB)
  • 44 Views
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Open Access
Article
Airway reactivity to mannitol is similarly increased in chronic cigarette and water pipe smokers
Andreas Scherr, Jerome Schmidlin, Silvio Albisser, Michael Tamm & Daiana Stolz
Pages: 157-163
Published online: 03 Jan 2018
AbstractforAirway reactivity to mannitol is similarly increased in chronic cigarette and water pipe smokers | Full Text | References | PDF (359.6 KB)
  • 50 Views
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Open Access
Article
2017 Global Initiative for Chronic Obstructive Lung Disease reclassifies half of COPD subjects to lower risk group
Marieann Högman, Johanna Sulku, Björn Ställberg, Christer Janson, Kristina Bröms, Hans Hedenström, Karin Lisspers & Andrei Malinovschi
Pages: 165-173
Published online: 03 Jan 2018
Abstractfor2017 Global Initiative for Chronic Obstructive Lung Disease reclassifies half of COPD subjects to lower risk group | Full Text | References | PDF (514.3 KB)
  • 93 Views
  • 17 CrossRef citations
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Open Access
Article
Religious coping and religiosity in patients with COPD following pulmonary rehabilitation
Guilherme PF da Silva, Francisco AB Nascimento, Tereza PM Macêdo, Maria T Morano, Rafael Mesquita & Eanes DB Pereira
Pages: 175-181
Published online: 04 Jan 2018
AbstractforReligious coping and religiosity in patients with COPD following pulmonary rehabilitation | Full Text | References | PDF (287.6 KB)
  • 127 Views
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Open Access

Perspectives

Article
Russian guidelines for the management of COPD: algorithm of pharmacologic treatment
Zaurbek Aisanov, Sergey Avdeev, Vladimir Arkhipov, Andrey Belevskiy, Alexander Chuchalin, Igor Leshchenko, Svetlana Ovcharenko, Evgeny Shmelev & Marc Miravitlles
Pages: 183-187
Published online: 08 Jan 2018
AbstractforRussian guidelines for the management of COPD: algorithm of pharmacologic treatment | Full Text | References | PDF (316.3 KB)
  • 265 Views
  • 31 CrossRef citations
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Open Access

Original Research

Article
Predictors of pneumonia on routine chest radiographs in patients with COPD: a post hoc analysis of two 1-year randomized controlled trials
David B Rubin, Harris A Ahmad, Michael O’Neal, Sophie Bennett, Sally Lettis, Dmitry V Galkin & Courtney Crim
Pages: 189-201
Published online: 08 Jan 2018
AbstractforPredictors of pneumonia on routine chest radiographs in patients with COPD: a post hoc analysis of two 1-year randomized controlled trials | Full Text | References | PDF (1.9 MB)
  • 59 Views
  • 3 CrossRef citations
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Open Access
Article
Relationship between exercise endurance and static hyperinflation in a post hoc analysis of two clinical trials in patients with COPD
Sally Singh, François Maltais, Lee Tombs, William A Fahy, Mitra Vahdati-Bolouri, Nicholas Locantore & John H Riley
Pages: 203-215
Published online: 08 Jan 2018
AbstractforRelationship between exercise endurance and static hyperinflation in a post hoc analysis of two clinical trials in patients with COPD | Full Text | References | PDF (2.9 MB)
  • 80 Views
  • 6 CrossRef citations
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Open Access
Article
Phenotyping COPD exacerbations using imaging and blood-based biomarkers
Nawaf M Alotaibi, Virginia Chen, Zsuzsanna Hollander, Cameron J Hague, Darra T Murphy, Jonathon A Leipsic, Mari L DeMarco, J Mark FitzGerald, Bruce M McManus, Raymond T Ng & Don D Sin
Pages: 217-229
Published online: 08 Jan 2018
AbstractforPhenotyping COPD exacerbations using imaging and blood-based biomarkers | Full Text | References | PDF (1.8 MB)
  • 131 Views
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Open Access

Review

Review Article
Which patients with moderate hypoxemia benefit from long-term oxygen therapy? Ways forward
Magnus Ekström & Thomas Ringbaek
Pages: 231-235
Published online: 09 Jan 2018
AbstractforWhich patients with moderate hypoxemia benefit from long-term oxygen therapy? Ways forward | Full Text | References | PDF (229.6 KB)
  • 95 Views
  • 6 CrossRef citations
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Open Access

Original Research

Article
Antibiotic-resistant Pseudomonas aeruginosa infection in patients with bronchiectasis: prevalence, risk factors and prognostic implications
Yong-hua Gao, Wei-jie Guan, Ya-nan Zhu, Rong-chang Chen & Guo-jun Zhang
Pages: 237-246
Published online: 09 Jan 2018
AbstractforAntibiotic-resistant Pseudomonas aeruginosa infection in patients with bronchiectasis: prevalence, risk factors and prognostic implications | Full Text | References | PDF (665 KB)
  • 132 Views
  • 16 CrossRef citations
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Open Access
Article
Independent determinants of disease-related quality of life in COPD – scope for nonpharmacologic interventions?
Sarah B Brien, Beth Stuart, Andrew P Dickens, Tony Kendrick, Rachel E Jordan, Paymane Adab & Mike Thomas
Pages: 247-256
Published online: 09 Jan 2018
AbstractforIndependent determinants of disease-related quality of life in COPD – scope for nonpharmacologic interventions? | Full Text | References | PDF (351 KB)
  • 86 Views
  • 16 CrossRef citations
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Open Access
Article
Efficacy of supervised maintenance exercise following pulmonary rehabilitation on health care use: a systematic review and meta-analysis
Alex R Jenkins, Holly Gowler, Ffion Curtis, Neil S Holden, Christopher Bridle & Arwel W Jones
Pages: 257-273
Published online: 10 Jan 2018
AbstractforEfficacy of supervised maintenance exercise following pulmonary rehabilitation on health care use: a systematic review and meta-analysis | Full Text | References | PDF (915.4 KB)
  • 214 Views
  • 43 CrossRef citations
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Open Access
Article
Economic burden of COPD in a Swedish cohort: the ARCTIC study
Karin Lisspers, Kjell Larsson, Gunnar Johansson, Christer Janson, Madlaina Costa-Scharplatz, Jean-Bernard Gruenberger, Milica Uhde, Leif Jorgensen, Florian S Gutzwiller & Björn Ställberg
Pages: 275-285
Published online: 20 Oct 2022
AbstractforEconomic burden of COPD in a Swedish cohort: the ARCTIC study | Full Text | References | PDF (6.1 MB)
  • 128 Views
  • 39 CrossRef citations
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Open Access
Article
Narrative medicine to improve the management and quality of life of patients with COPD: the first experience applying parallel chart in Italy
Paolo Banfi, Antonietta Cappuccio, Maura E Latella, Luigi Reale, Elisa Muscianisi & Maria Giulia Marini
Pages: 287-297
Published online: 11 Jan 2018
AbstractforNarrative medicine to improve the management and quality of life of patients with COPD: the first experience applying parallel chart in Italy | Full Text | References | PDF (534.5 KB)
  • 184 Views
  • 21 CrossRef citations
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Open Access
Article
Epidemiological study of PM2.5 and risk of COPD-related hospital visits in association with particle constituents in Chuncheon, Korea
Yong Suk Jo, Myoung Nam Lim, Young-Ji Han & Woo Jin Kim
Pages: 299-307
Published online: 12 Jan 2018
AbstractforEpidemiological study of PM2.5 and risk of COPD-related hospital visits in association with particle constituents in Chuncheon, Korea | Full Text | References | PDF (361.7 KB)
  • 202 Views
  • 32 CrossRef citations
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Open Access
Article
The annual direct costs of stable COPD in Greece
Eirini Stafyla, Mary Geitona, Theodora Kerenidi, Athina Economou, Zoe Daniil & Konstantinos I Gourgoulianis
Pages: 309-315
Published online: 15 Jan 2018
AbstractforThe annual direct costs of stable COPD in Greece | Full Text | References | PDF (303.6 KB)
  • 85 Views
  • 12 CrossRef citations
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Open Access
Article
Risk of empyema in patients with COPD
Hsueh-Yi Lu & Kuang-Ming Liao
Pages: 317-324
Published online: 15 Jan 2018
AbstractforRisk of empyema in patients with COPD | Full Text | References | PDF (649.5 KB)
  • 63 Views
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Open Access

Commentary

Article Commentary
Low back pain and gastroesophageal reflux in patients with COPD: the disease in the breath
Bruno Bordoni, Fabiola Marelli, Bruno Morabito, Beatrice Sacconi, Philippe Caiazzo & Roberto Castagna
Pages: 325-334
Published online: 17 Jan 2018
AbstractforLow back pain and gastroesophageal reflux in patients with COPD: the disease in the breath | Full Text | References | PDF (429.3 KB)
  • 301 Views
  • 16 CrossRef citations
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Open Access

Review

Review Article
Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease
Donald P Tashkin & Michael E Wechsler
Pages: 335-349
Published online: 17 Jan 2018
AbstractforRole of eosinophils in airway inflammation of chronic obstructive pulmonary disease | Full Text | References | PDF (743.2 KB)
  • 293 Views
  • 84 CrossRef citations
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Open Access

Original Research

Article
Impact of using the new GOLD classification on the distribution of COPD severity in clinical practice
Marcos Hernández, Gabriel García, Jimena Falco, Agustín R García, Vanina Martín, Manuel Ibarrola & Silvia Quadrelli
Pages: 351-356
Published online: 17 Jan 2018
AbstractforImpact of using the new GOLD classification on the distribution of COPD severity in clinical practice | Full Text | References | PDF (371.2 KB)
  • 185 Views
  • 8 CrossRef citations
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Open Access
Article
The clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease
Ming Zhang, Jingjing Tang, Jiafeng Yin, Xiaoying Wang, Xiangli Feng, Xia Yang, Hu Shan, Qiuhong Zhang, Jie Zhang & Yali Li
Pages: 357-363
Published online: 19 Jan 2018
AbstractforThe clinical implication of serum cyclophilin A in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (2 MB)
  • 63 Views
  • 17 CrossRef citations
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Open Access
Article
Symptom burden and self-management in persons with chronic obstructive pulmonary disease
Heidi B Bringsvor, Knut Skaug, Eva Langeland, Bjørg Frøysland Oftedal, Jörg Assmus, Doris Gundersen, Richard H Osborne & Signe Berit Bentsen
Pages: 365-373
Published online: 24 Jan 2018
AbstractforSymptom burden and self-management in persons with chronic obstructive pulmonary disease | Full Text | References | PDF (314.1 KB)
  • 200 Views
  • 24 CrossRef citations
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Open Access
Article
Emphysema and bronchiectasis in COPD patients with previous pulmonary tuberculosis: computed tomography features and clinical implications
Jianmin Jin, Shuling Li, Wenling Yu, Xiaofang Liu & Yongchang Sun
Pages: 375-384
Published online: 24 Jan 2018
AbstractforEmphysema and bronchiectasis in COPD patients with previous pulmonary tuberculosis: computed tomography features and clinical implications | Full Text | References | PDF (1.3 MB)
  • 212 Views
  • 20 CrossRef citations
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Open Access
Article
Sex-specific cardiopulmonary exercise testing indices to estimate the severity of inoperable chronic thromboembolic pulmonary hypertension
Tian-Xiang Chen, Bigyan Pudasaini, Jian Guo, Su-Gang Gong, Rong Jiang, Lan Wang, Qin-Hua Zhao, Wen-Hui Wu, Ping Yuan & Jin-Ming Liu
Pages: 385-397
Published online: 26 Jan 2018
AbstractforSex-specific cardiopulmonary exercise testing indices to estimate the severity of inoperable chronic thromboembolic pulmonary hypertension | Full Text | References | PDF (2.6 MB)
  • 58 Views
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Open Access

Expert Opinion

Editorial
Management of airway mucus hypersecretion in chronic airway inflammatory disease: Chinese expert consensus (English edition)
Yongchun Shen, Shaoguang Huang, Jian Kang, Jiangtao Lin, Kefang Lai, Yongchang Sun, Wei Xiao, Lan Yang, Wanzhen Yao, Shaoxi Cai, Kewu Huang & Fuqiang Wen
Pages: 399-407
Published online: 30 Jan 2018
AbstractforManagement of airway mucus hypersecretion in chronic airway inflammatory disease: Chinese expert consensus (English edition) | Full Text | References | PDF (450.1 KB)
  • 421 Views
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Open Access

Original Research

Article
The YKL-40 protein is a potential biomarker for COPD: a meta-analysis and systematic review
Xiang Tong, Dongguang Wang, Sitong Liu, Yao Ma, Zhenzhen Li, Panwen Tian & Hong Fan
Pages: 409-418
Published online: 30 Jan 2018
AbstractforThe YKL-40 protein is a potential biomarker for COPD: a meta-analysis and systematic review | Full Text | References | PDF (1,002.3 KB)
  • 86 Views
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Open Access

Review

Review Article
Alpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications
Kenneth R Chapman, Joanna Chorostowska-Wynimko, A Rembert Koczulla, Ilaria Ferrarotti & Noel G McElvaney
Pages: 419-432
Published online: 31 Jan 2018
AbstractforAlpha 1 antitrypsin to treat lung disease in alpha 1 antitrypsin deficiency: recent developments and clinical implications | Full Text | References | PDF (808.2 KB)
  • 205 Views
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Open Access

Original Research

Article
The distribution of blood eosinophil levels in a Japanese COPD clinical trial database and in the rest of the world
Neil Barnes, Takeo Ishii, Nobuyuki Hizawa, Dawn Midwinter, Mark James, Emma Hilton & Paul W Jones
Pages: 433-440
Published online: 02 Feb 2018
AbstractforThe distribution of blood eosinophil levels in a Japanese COPD clinical trial database and in the rest of the world | Full Text | References | PDF (396.6 KB)
  • 51 Views
  • 7 CrossRef citations
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Open Access
Article
Cadmium nanoparticles citrullinate cytokeratins within lung epithelial cells: cadmium as a potential cause of citrullination in chronic obstructive pulmonary disease
David Hutchinson, Judith Müller, Joseph E McCarthy, Yurii K Gun’ko, Navin Kumar Verma, Xuezhi Bi, Luisana Di Cristo, Laura Kickham, Dania Movia, Adriele Prina-Mello & Yuri Volkov
Pages: 441-449
Published online: 31 Jan 2018
AbstractforCadmium nanoparticles citrullinate cytokeratins within lung epithelial cells: cadmium as a potential cause of citrullination in chronic obstructive pulmonary disease | Full Text | References | PDF (2.6 MB)
  • 79 Views
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Open Access
Article
Do not do in COPD: consensus statement on overuse
Felipe Villar-Álvarez, Raúl Moreno-Zabaleta, Jose Joaquin Mira-Solves, Eduardo Calvo-Corbella, Salvador Díaz-Lobato, Fernando González-Torralba, Ascensión Hernando-Sanz, Sara Núñez-Palomo, Sergio Salgado-Aranda, Beatriz Simón-Rodríguez, Paz Vaquero-Lozano, Isabel María Navarro-Soler & On behalf of “Do not do in COPD” Working Group of the Madrid Society of Pulmonology and Thoracic Surgery (Neumomadrid)
Pages: 451-463
Published online: 02 Feb 2018
AbstractforDo not do in COPD: consensus statement on overuse | Full Text | References | PDF (537.8 KB)
  • 116 Views
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Open Access
Article
The minimal important difference for target lobe volume reduction after endoscopic valve therapy
D Gompelmann, K Kontogianni, M Schuhmann, R Eberhardt, CP Heussel & FJ Herth
Pages: 465-472
Published online: 01 Feb 2018
AbstractforThe minimal important difference for target lobe volume reduction after endoscopic valve therapy | Full Text | References | PDF (2 MB)
  • 73 Views
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Open Access
Article
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function
Tianwen Lai, Yanyu Li, Zongjiong Mai, Xiaoxia Wen, Yingying Lv, Zhanqing Xie, Quanchao Lv, Min Chen, Dong Wu & Bin Wu
Pages: 473-486
Published online: 05 Feb 2018
AbstractforAnnexin A1 is elevated in patients with COPD and affects lung fibroblast function | Full Text | References | PDF (3.2 MB)
  • 66 Views
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Open Access
Article
Missed diagnosis and overtreatment of COPD among smoking primary care population in Central Greece: old problems persist
Eirini Stafyla, Ourania S Kotsiou, Konstantina Deskata & Konstantinos I Gourgoulianis
Pages: 487-498
Published online: 05 Feb 2018
AbstractforMissed diagnosis and overtreatment of COPD among smoking primary care population in Central Greece: old problems persist | Full Text | References | PDF (439.6 KB)
  • 106 Views
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Open Access
Article
Long-term health-related quality-of-life and symptom response profiles with arformoterol in COPD: results from a 52-week trial
James F Donohue, Vamsi K Bollu, Donald E Stull, Lauren M Nelson, Valerie SL Williams, Michael D Stensland & Nicola A Hanania
Pages: 499-508
Published online: 05 Feb 2018
AbstractforLong-term health-related quality-of-life and symptom response profiles with arformoterol in COPD: results from a 52-week trial | Full Text | References | PDF (918.9 KB)
  • 51 Views
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Open Access
Article
Incidence and risk of chronic obstructive pulmonary disease in a Korean community-based cohort
Ah Young Leem, Boram Park, Young Sam Kim, Ji Ye Jung & Sungho Won
Pages: 509-517
Published online: 05 Feb 2018
AbstractforIncidence and risk of chronic obstructive pulmonary disease in a Korean community-based cohort | Full Text | References | PDF (519.2 KB)
  • 131 Views
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Open Access
Article
Alterations of the default mode network and cognitive impairments in patients with chronic obstructive pulmonary disease
Xianwei Hu, Haibao Wang, Youhui Tu, Mengdi Fei, Minmin Yin, Guanghe Fei & Yongqiang Yu
Pages: 519-528
Published online: 07 Feb 2018
AbstractforAlterations of the default mode network and cognitive impairments in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (5.1 MB)
  • 105 Views
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Open Access
Article
Immune cell response to strenuous resistive breathing: comparison with whole body exercise and the effects of antioxidants
Andreas Asimakos, Dimitrios Toumpanakis, Maria-Helena Karatza, Spyridoula Vasileiou, Paraskevi Katsaounou, Zafeiria Mastora & Theodoros Vassilakopoulos
Pages: 529-545
Published online: 07 Feb 2018
AbstractforImmune cell response to strenuous resistive breathing: comparison with whole body exercise and the effects of antioxidants | Full Text | References | PDF (1 MB)
  • 95 Views
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Open Access
Article
CT densitometry in emphysema: a systematic review of its clinical utility
Diana Crossley, Mary Renton, Muhammad Khan, Emma V Low & Alice M Turner
Pages: 547-563
Published online: 07 Feb 2018
AbstractforCT densitometry in emphysema: a systematic review of its clinical utility | Full Text | References | PDF (1.3 MB)
  • 127 Views
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Open Access

Clinical Trial Report

Article
New bacterial growth in bronchial secretions after bronchoscopic valve implantation
Nilab Sarmand, Daniela Gompelmann, Konstantina Kontogianni, Markus Polke, Felix JF Herth & Ralf Eberhardt
Pages: 565-570
Published online: 08 Feb 2018
AbstractforNew bacterial growth in bronchial secretions after bronchoscopic valve implantation | Full Text | References | PDF (244 KB)
  • 72 Views
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Open Access

Original Research

Article
Endoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium
Yong Wang, Jie-Sen Zhou, Xu-Chen Xu, Zhou-Yang Li, Hai-Pin Chen, Song-Min Ying, Wen Li, Hua-Hao Shen & Zhi-Hua Chen
Pages: 571-581
Published online: 09 Feb 2018
AbstractforEndoplasmic reticulum chaperone GRP78 mediates cigarette smoke-induced necroptosis and injury in bronchial epithelium | Full Text | References | PDF (3 MB)
  • 72 Views
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Open Access
Article
Burden of COPD in Nepal
Tara Ballav Adhikari, Dinesh Neupane & Per Kallestrup
Pages: 583-589
Published online: 20 Oct 2022
AbstractforBurden of COPD in Nepal | Full Text | References | PDF (439.6 KB)
  • 501 Views
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Open Access
Article
Mixed Th2 and non-Th2 inflammatory pattern in the asthma–COPD overlap: a network approach
Luis Pérez de Llano, Borja G Cosío, Amanda Iglesias, Natividad de las Cuevas, Juan Jose Soler-Cataluña, Jose Luis Izquierdo, Jose Luis López-Campos, Carmen Calero, Vicente Plaza, Marc Miravitlles, Alfons Torrego, Eva Martinez-Moragon, Joan B Soriano, Antolin Lopez Viña, Irina Bobolea & On behalf of the CHACOS Study Group
Pages: 591-601
Published online: 12 Feb 2018
AbstractforMixed Th2 and non-Th2 inflammatory pattern in the asthma–COPD overlap: a network approach | Full Text | References | PDF (1.3 MB)
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Open Access

Corrigendum

Correction
Reduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPD [Corrigendum]
Page: 603
Published online: 13 Feb 2018
CitationforReduced nuclear translocation of serum response factor is associated with skeletal muscle atrophy in a cigarette smoke-induced mouse model of COPD [Corrigendum] | Full Text | PDF (134 KB)
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Original Research

Article
Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial
Robert A Wise, Peter MA Calverley, Kerstine Carter, Emmanuelle Clerisme-Beaty, Norbert Metzdorf & Antonio Anzueto
Pages: 605-616
Published online: 14 Feb 2018
AbstractforSeasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial | Full Text | References | PDF (903.2 KB)
  • 236 Views
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Article
Safety and effectiveness of the high-frequency chest wall oscillation vs intrapulmonary percussive ventilation in patients with severe COPD
Antonello Nicolini, Bruna Grecchi, Maura Ferrari-Bravo & Cornelius Barlascini
Pages: 617-625
Published online: 16 Feb 2018
AbstractforSafety and effectiveness of the high-frequency chest wall oscillation vs intrapulmonary percussive ventilation in patients with severe COPD | Full Text | References | PDF (1.1 MB)
  • 405 Views
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Article
TNF promoter polymorphisms are associated with genetic susceptibility in COPD secondary to tobacco smoking and biomass burning
Juan Manuel Reséndiz-Hernández, Enrique Ambrocio-Ortiz, Gloria Pérez-Rubio, Luis Alberto López-Flores, Edgar Abarca-Rojano, Gandhi Fernando Pavón-Romero, Fernando Flores-Trujillo, Rafael de Jesús Hernández-Zenteno, Ángel Camarena, Martha Pérez-Rodríguez, Ana María Salazar, Alejandra Ramírez-Venegas & Ramcés Falfán-Valencia
Pages: 627-637
Published online: 16 Feb 2018
AbstractforTNF promoter polymorphisms are associated with genetic susceptibility in COPD secondary to tobacco smoking and biomass burning | Full Text | References | PDF (864.6 KB)
  • 75 Views
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Article
Relationship of annual change in bone mineral density with extent of emphysematous lesions and pulmonary function in patients with COPD
Kenichi Goto, Emiko Ogawa, Kaoruko Shimizu, Hironi Makita, Hidenobu Suzuki, Yoshiki Kawata, Noboru Niki, Masaharu Nishimura & Yasutaka Nakano
Pages: 639-644
Published online: 20 Feb 2018
AbstractforRelationship of annual change in bone mineral density with extent of emphysematous lesions and pulmonary function in patients with COPD | Full Text | References | PDF (612.9 KB)
  • 48 Views
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Article
The outcome and the influencing factors of the age of onset in post-mortem of chronic bronchitis patients: a retrospective study
Linyun Zhu, Zhenhua Ni, Xuming Luo, Zhuhua Zhang, Shiqiang Wang, Ziyu Meng, Xiandong Gu & Xiongbiao Wang
Pages: 645-652
Published online: 20 Oct 2022
AbstractforThe outcome and the influencing factors of the age of onset in post-mortem of chronic bronchitis patients: a retrospective study | Full Text | References | PDF (921.9 KB)
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Article
Real-life evaluation of COPD treatment in a Bulgarian population: a 1-year prospective, observational, noninterventional study
Yavor Ivanov, Ivan Nikolaev & Imola Nemeth
Pages: 653-663
Published online: 22 Feb 2018
AbstractforReal-life evaluation of COPD treatment in a Bulgarian population: a 1-year prospective, observational, noninterventional study | Full Text | References | PDF (1.2 MB)
  • 74 Views
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Article
Obstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005–2008 National Health and Nutrition Examination Survey
Wei Du, Jun Liu, Jianlong Zhou, Dan Ye, Yan OuYang & Qingnan Deng
Pages: 665-674
Published online: 27 Feb 2018
AbstractforObstructive sleep apnea, COPD, the overlap syndrome, and mortality: results from the 2005–2008 National Health and Nutrition Examination Survey | Full Text | References | PDF (463.1 KB)
  • 298 Views
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Article
Co-existence of COPD and bronchiectasis: a risk factor for a high ratio of main pulmonary artery to aorta diameter (PA:A) from computed tomography in COPD patients
Shuang Dou, Chunyan Zheng, Xiuli Ji, Wei Wang, Mengshuang Xie, Liwei Cui & Wei Xiao
Pages: 675-681
Published online: 26 Feb 2018
AbstractforCo-existence of COPD and bronchiectasis: a risk factor for a high ratio of main pulmonary artery to aorta diameter (PA:A) from computed tomography in COPD patients | Full Text | References | PDF (684.4 KB)
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Review

Review Article
Early life insults as determinants of chronic obstructive pulmonary disease in adult life
Osman Savran & Charlotte Suppli Ulrik
Pages: 683-693
Published online: 20 Oct 2022
AbstractforEarly life insults as determinants of chronic obstructive pulmonary disease in adult life | Full Text | References | PDF (346.9 KB)
  • 169 Views
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Original Research

Article
Factors associated with appropriate inhaler use in patients with COPD – lessons from the REAL survey
David Price, Dorothy L Keininger, Boomi Viswanad, Matthias Gasser, Susann Walda & Florian S Gutzwiller
Pages: 695-702
Published online: 26 Feb 2018
AbstractforFactors associated with appropriate inhaler use in patients with COPD – lessons from the REAL survey | Full Text | References | PDF (532.8 KB)
  • 332 Views
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Article
Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
Zhilin Zeng, Miao Li, Jinkun Chen, Qinghai Li, Qin Ning, Jianping Zhao, Yongjian Xu, Jungang Xie & Jun Yu
Pages: 703-715
Published online: 28 Feb 2018
AbstractforReduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD | Full Text | References | PDF (4.5 MB)
  • 77 Views
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Article
The relationship between exercise capacity and different functional markers in pulmonary rehabilitation for COPD
Maria Kerti, Zsuzsanna Balogh, Krisztina Kelemen & Janos T Varga
Pages: 717-724
Published online: 28 Feb 2018
AbstractforThe relationship between exercise capacity and different functional markers in pulmonary rehabilitation for COPD | Full Text | References | PDF (5.3 MB)
  • 533 Views
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Article
Effect of the economic crisis on the use of health and home care services among Spanish COPD patients
Javier de Miguel-Diez, Ana Lopez-de-Andres, Valentin Herandez-Barrera, Isabel Jimenez-Trujillo, Luis Puente-Maestu, Alicia Cerezo-Lajas & Rodrigo Jimenez-Garcia
Pages: 725-739
Published online: 20 Oct 2022
AbstractforEffect of the economic crisis on the use of health and home care services among Spanish COPD patients | Full Text | References | PDF (487.7 KB)
  • 50 Views
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Article
The effect of environmental factors on the differential expression of miRNAs in patients with chronic obstructive pulmonary disease: a pilot clinical study
Peng-Fei Liu, Peng Yan, Da-Hui Zhao, Wen-Fang Shi, Song Meng, Yang Liu, Bin Liu, Guo-Feng Li & Li-Xin Xie
Pages: 741-751
Published online: 28 Feb 2018
AbstractforThe effect of environmental factors on the differential expression of miRNAs in patients with chronic obstructive pulmonary disease: a pilot clinical study | Full Text | References | PDF (935 KB)
  • 55 Views
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Review

Review Article
Home noninvasive ventilatory support for patients with chronic obstructive pulmonary disease: patient selection and perspectives
Jan Hendrik Storre, Jens Callegari, Friederike Sophie Magnet, Sarah Bettina Schwarz, Marieke Leontine Duiverman, Peter Jan Wijkstra & Wolfram Windisch
Pages: 753-760
Published online: 20 Oct 2022
AbstractforHome noninvasive ventilatory support for patients with chronic obstructive pulmonary disease: patient selection and perspectives | Full Text | References | PDF (528.4 KB)
  • 110 Views
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Original Research

Article
Relationship between the presence of bronchiectasis and acute exacerbation in Thai COPD patients
Theerasuk Kawamatawong, Jitsupa Onnipa & Thitiporn Suwatanapongched
Pages: 761-769
Published online: 02 Mar 2018
AbstractforRelationship between the presence of bronchiectasis and acute exacerbation in Thai COPD patients | Full Text | References | PDF (2.7 MB)
  • 101 Views
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Article
The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages
Simon R Lea, Sophie L Reynolds, Manminder Kaur, Karen D Simpson, Simon R Hall, Edith M Hessel & Dave Singh
Pages: 771-780
Published online: 02 Mar 2018
AbstractforThe effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages | Full Text | References | PDF (947.4 KB)
  • 57 Views
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Article
Factors influencing treatment escalation from long-acting muscarinic antagonist monotherapy to triple therapy in patients with COPD: a retrospective THIN-database analysis
John R Hurst, Maria Dilleen, Kevin Morris, Siân Hills, Birol Emir & Rupert Jones
Pages: 781-792
Published online: 05 Mar 2018
AbstractforFactors influencing treatment escalation from long-acting muscarinic antagonist monotherapy to triple therapy in patients with COPD: a retrospective THIN-database analysis | Full Text | References | PDF (652.8 KB)
  • 93 Views
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Article
Metformin use and health care utilization in patients with coexisting chronic obstructive pulmonary disease and diabetes mellitus
Raju Bishwakarma, Wei Zhang, Yu-Li Lin, Yong-Fang Kuo, Victor J Cardenas & Gulshan Sharma
Pages: 793-800
Published online: 05 Mar 2018
AbstractforMetformin use and health care utilization in patients with coexisting chronic obstructive pulmonary disease and diabetes mellitus | Full Text | References | PDF (371.6 KB)
  • 147 Views
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Article
Distinct pain profiles in patients with chronic obstructive pulmonary disease
Signe B Bentsen, Christine Miaskowski, Bruce A Cooper, Vivi L Christensen, Anne H Henriksen, Are M Holm & Tone Rustøen
Pages: 801-811
Published online: 06 Mar 2018
AbstractforDistinct pain profiles in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (528.9 KB)
  • 86 Views
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Article
Use of a 4-week up-titration regimen of roflumilast in patients with severe COPD
Henrik Watz, Nitin Bagul, Klaus F Rabe, Stephen Rennard, Vijay KT Alagappan, Jonas Román, Axel Facius & Peter MA Calverley
Pages: 813-822
Published online: 06 Mar 2018
AbstractforUse of a 4-week up-titration regimen of roflumilast in patients with severe COPD | Full Text | References | PDF (1.3 MB)
  • 78 Views
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Article
Depressive status explains a significant amount of the variance in COPD assessment test (CAT) scores
Marc Miravitlles, Jesús Molina, José Antonio Quintano, Anna Campuzano, Joselín Pérez, Carlos Roncero & On behalf of the DEPREPOC study investigators
Pages: 823-831
Published online: 06 Mar 2018
AbstractforDepressive status explains a significant amount of the variance in COPD assessment test (CAT) scores | Full Text | References | PDF (1.1 MB)
  • 136 Views
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Clinical Trial Report

Article
Changes in ventilation–perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling
Bita Hajian, Jan De Backer, Wim Vos, Wouter H van Geffen, Paul De Winter, Omar Usmani, Tony Cahn, Huib AM Kerstjens, Massimo Pistolesi & Wilfried De Backer
Pages: 833-842
Published online: 06 Mar 2018
AbstractforChanges in ventilation–perfusion during and after an COPD exacerbation: an assessment using fluid dynamic modeling | Full Text | References | PDF (1.1 MB)
  • 207 Views
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Original Research

Article
Clinical impact of episodic nocturnal hypercapnia and its treatment with noninvasive positive pressure ventilation in patients with stable advanced COPD
Takamasa Kitajima, Satoshi Marumo, Hiroshi Shima, Masahiro Shirata, Satoru Kawashima, Daiki Inoue, Yuko Katayama, Ryo Itotani, Minoru Sakuramoto & Motonari Fukui
Pages: 843-853
Published online: 20 Oct 2022
AbstractforClinical impact of episodic nocturnal hypercapnia and its treatment with noninvasive positive pressure ventilation in patients with stable advanced COPD | Full Text | References | PDF (1.4 MB)
  • 65 Views
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Article
Excess risk of major vascular diseases associated with airflow obstruction: a 9-year prospective study of 0.5 million Chinese adults
Om P Kurmi, Liming Li, Kourtney J Davis, Jenny Wang, Derrick A Bennett, Ka Hung Chan, Ling Yang, Yiping Chen, Yu Guo, Zheng Bian, Junshi Chen, Liuping Wei, Donghui Jin, Rory Collins, Richard Peto, Zhengming Chen & On behalf of the China Kadoorie Biobank collaborative group
Pages: 855-865
Published online: 08 Mar 2018
AbstractforExcess risk of major vascular diseases associated with airflow obstruction: a 9-year prospective study of 0.5 million Chinese adults | Full Text | References | PDF (579 KB)
  • 51 Views
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Article
Comparative effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on the risk of pneumonia and severe exacerbations in patients with COPD
Chih-Cheng Lai, Ya-Hui Wang, Cheng-Yi Wang, Hao-Chien Wang, Chong-Jen Yu, Likwang Chen & On behalf of the Taiwan Clinical Trial Consortium for Respiratory Diseases (TCORE)
Pages: 867-874
Published online: 08 Mar 2018
AbstractforComparative effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on the risk of pneumonia and severe exacerbations in patients with COPD | Full Text | References | PDF (415.8 KB)
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Letter

Letter
Perspectives on narrative medicine
Amir-Seena Saberi-Movahed, Syed Waqar & Ahmad Salha
Pages: 875-877
Published online: 09 Mar 2018
First Page PreviewforPerspectives on narrative medicine | Full Text | References | PDF (211.6 KB)
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Original Research

Article
Knowledge and pharmaceutical care practice regarding inhaled therapy among registered and unregistered pharmacists: an urgent need for a patient-oriented health care educational program in Iraq
Shaymaa Abdalwahed Abdulameer
Pages: 879-888
Published online: 12 Mar 2018
AbstractforKnowledge and pharmaceutical care practice regarding inhaled therapy among registered and unregistered pharmacists: an urgent need for a patient-oriented health care educational program in Iraq | Full Text | References | PDF (349.3 KB)
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Article
Use of clinical characteristics to predict spirometric classification of obstructive lung disease
Steven J Pascoe, Wei Wu, Kathryn A Collison, Linda M Nelsen, Keele E Wurst & Laurie A Lee
Pages: 889-902
Published online: 12 Mar 2018
AbstractforUse of clinical characteristics to predict spirometric classification of obstructive lung disease | Full Text | References | PDF (2.2 MB)
  • 88 Views
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Article
Comparison of the fixed ratio and the Z-score of FEV1/FVC in the elderly population: a long-term mortality analysis from the Third National Health and Nutritional Examination Survey
Dong Kyu Oh, Seunghee Baek, Sei Won Lee, Jae Seung Lee, Sang-Do Lee & Yeon-Mok Oh
Pages: 903-915
Published online: 14 Mar 2018
AbstractforComparison of the fixed ratio and the Z-score of FEV1/FVC in the elderly population: a long-term mortality analysis from the Third National Health and Nutritional Examination Survey | Full Text | References | PDF (4.5 MB)
  • 88 Views
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Article
A functional SNP upstream of the ADRB2 gene is associated with COPD
Jin-Xiu Li, Wei-Ping Fu, Jing Zhang, Xiao-Hua Zhang, Chang Sun, Lu-Ming Dai, Li Zhong, Li Yu & Ya-Ping Zhang
Pages: 917-925
Published online: 16 Mar 2018
AbstractforA functional SNP upstream of the ADRB2 gene is associated with COPD | Full Text | References | PDF (812.9 KB)
  • 87 Views
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Article
Maintenance inhaler preference, attribute importance, and satisfaction in prescribing physicians and patients with asthma, COPD, or asthma–COPD overlap syndrome consulting for routine care
Bo Ding, Mark Small, Gina Scheffel & Ulf Holmgren
Pages: 927-936
Published online: 16 Mar 2018
AbstractforMaintenance inhaler preference, attribute importance, and satisfaction in prescribing physicians and patients with asthma, COPD, or asthma–COPD overlap syndrome consulting for routine care | Full Text | References | PDF (565.6 KB)
  • 231 Views
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Article
Lack of association between airflow limitation and recurrence of venous thromboembolism among cancer patients with pulmonary embolism
Sun Hye Shin, Danbee Kang, Juhee Cho, Haseong Chang, Min Sun Kim, Su Yeon Lee, Hyun Lee, Hojoong Kim, Duk-Kyung Kim, Eun Kyoung Kim & Hye Yun Park
Pages: 937-943
Published online: 20 Mar 2018
AbstractforLack of association between airflow limitation and recurrence of venous thromboembolism among cancer patients with pulmonary embolism | Full Text | References | PDF (459.8 KB)
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Article
Pharmacokinetics of glycopyrronium/formoterol fumarate dihydrate delivered via metered dose inhaler using co-suspension delivery technology in patients with moderate-to-very severe COPD
Gary T Ferguson, Roberto Rodriguez-Roisin, Colin Reisner, Andrea Maes, Shahid Siddiqui & Ubaldo J Martin
Pages: 945-953
Published online: 21 Mar 2018
AbstractforPharmacokinetics of glycopyrronium/formoterol fumarate dihydrate delivered via metered dose inhaler using co-suspension delivery technology in patients with moderate-to-very severe COPD | Full Text | References | PDF (791.7 KB)
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Research Letter

Article
A high COPD assessment test score may predict anxiety in COPD
Hilman Harryanto, Sally Burrows & Yuben Moodley
Pages: 955-957
Published online: 21 Mar 2018
First Page PreviewforA high COPD assessment test score may predict anxiety in COPD | Full Text | References | PDF (217.4 KB)
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Original Research

Article
Cigarette smoke exposure promotes differentiation of CD4+ T cells toward Th17 cells by CD40–CD40L costimulatory pathway in mice
Yi Liang, Ying Shen, Liangjian Kuang, Guang Zhou, Longju Zhang, Xiaoning Zhong, Jianquan Zhang & Jifeng Liu
Pages: 959-968
Published online: 21 Mar 2018
AbstractforCigarette smoke exposure promotes differentiation of CD4+ T cells toward Th17 cells by CD40–CD40L costimulatory pathway in mice | Full Text | References | PDF (1.5 MB)
  • 68 Views
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Article
Do patients and carers agree on symptom burden in advanced COPD?
Emma Mi, Ella Mi, Gail Ewing, Patrick White, Ravi Mahadeva, A Carole Gardener, Morag Farquhar & On behalf of the Living with Breathlessness Study Team
Pages: 969-977
Published online: 22 Mar 2018
AbstractforDo patients and carers agree on symptom burden in advanced COPD? | Full Text | References | PDF (337 KB)
  • 67 Views
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Article
Long-term oxygen therapy in COPD patients: population-based cohort study on mortality
Nikolay Pavlov, Alan Gary Haynes, Armin Stucki, Peter Jüni & Sebastian Robert Ott
Pages: 979-988
Published online: 22 Mar 2018
AbstractforLong-term oxygen therapy in COPD patients: population-based cohort study on mortality | Full Text | References | PDF (634.2 KB)
  • 432 Views
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Article
The effect of electronic cigarette and tobacco smoke exposure on COPD bronchial epithelial cell inflammatory responses
Andrew Higham, Declan Bostock, George Booth, Josiah V Dungwa & Dave Singh
Pages: 989-1000
Published online: 23 Mar 2018
AbstractforThe effect of electronic cigarette and tobacco smoke exposure on COPD bronchial epithelial cell inflammatory responses | Full Text | References | PDF (1.9 MB)
  • 344 Views
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Article
Long-term evolution of lung function in individuals with alpha-1 antitrypsin deficiency from the Spanish registry (REDAAT)
Cristina Esquinas, Sonia Serreri, Miriam Barrecheguren, Esther Rodriguez, Alexa Nuñez, Francisco Casas-Maldonado, Ignacio Blanco, Pietro Pirina, Beatriz Lara & Marc Miravitlles
Pages: 1001-1007
Published online: 20 Oct 2022
AbstractforLong-term evolution of lung function in individuals with alpha-1 antitrypsin deficiency from the Spanish registry (REDAAT) | Full Text | References | PDF (372.7 KB)
  • 75 Views
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Article
The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial
Naimish R Patel, Danen M Cunoosamy, Malin Fagerås, Ziad Taib, Sara Asimus, Tove Hegelund-Myrbäck, Sofia Lundin, Katerina Pardali, Nisha Kurian, Eva Ersdal, Cecilia Kristensson, Katarina Korsback, Robert Palmér, Mary N Brown, Steven Greenaway, Leonard Siew, Graham W Clarke, Stephen I Rennard, Barry J Make, Robert A Wise & Paul Jansson
Pages: 1009-1019
Published online: 27 Mar 2018
AbstractforThe development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial | Full Text | References | PDF (1.2 MB)
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Review

Review Article
Support needs of patients with COPD: a systematic literature search and narrative review
A Carole Gardener, Gail Ewing, Isla Kuhn & Morag Farquhar
Pages: 1021-1035
Published online: 26 Mar 2018
AbstractforSupport needs of patients with COPD: a systematic literature search and narrative review | Full Text | References | PDF (396.8 KB)
  • 1339 Views
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Original Research

Article
Respiratory parameters predict poor outcome in COPD patients, category GOLD 2017 B
Kristian Brat, Marek Plutinsky, Karel Hejduk, Michal Svoboda, Patrice Popelkova, Jaromir Zatloukal, Eva Volakova, Miroslava Fecaninova, Lucie Heribanova & Vladimir Koblizek
Pages: 1037-1052
Published online: 26 Mar 2018
AbstractforRespiratory parameters predict poor outcome in COPD patients, category GOLD 2017 B | Full Text | References | PDF (744.4 KB)
  • 143 Views
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Article
Harmful impact of air pollution on severe acute exacerbation of chronic obstructive pulmonary disease: particulate matter is hazardous
Juwhan Choi, Jee Youn Oh, Young Seok Lee, Kyung Hoon Min, Gyu Young Hur, Sung Yong Lee, Kyung Ho Kang & Jae Jeong Shim
Pages: 1053-1059
Published online: 28 Mar 2018
AbstractforHarmful impact of air pollution on severe acute exacerbation of chronic obstructive pulmonary disease: particulate matter is hazardous | Full Text | References | PDF (563.7 KB)
  • 216 Views
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Article
Risk factors for respiratory hospitalizations in a population of patients with a clinical diagnosis of COPD
Jovica Veljanovski & Daniel R Ouellette
Pages: 1061-1069
Published online: 28 Mar 2018
AbstractforRisk factors for respiratory hospitalizations in a population of patients with a clinical diagnosis of COPD | Full Text | References | PDF (464.4 KB)
  • 40 Views
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Article
Description of nighttime cough epochs in patients with stable COPD GOLD II–IV
Patrick Fischer, Volker Gross, Johannes Kroenig, Andreas Weissflog, Olaf Hildebrandt, Keywan Sohrabi & Ulrich Koehler
Pages: 1071-1078
Published online: 03 Apr 2018
AbstractforDescription of nighttime cough epochs in patients with stable COPD GOLD II–IV | Full Text | References | PDF (1.4 MB)
  • 94 Views
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Article
Cost-effectiveness analysis of a fixed-dose combination of indacaterol and glycopyrronium as maintenance treatment for COPD
Ming-Cheng Chan, Elise Chia-Hui Tan & Ming-Chin Yang
Pages: 1079-1088
Published online: 04 Apr 2018
AbstractforCost-effectiveness analysis of a fixed-dose combination of indacaterol and glycopyrronium as maintenance treatment for COPD | Full Text | References | PDF (914.3 KB)
  • 58 Views
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Review

Review Article
Practical considerations when prescribing a long-acting muscarinic antagonist for patients with COPD
Anthony D D’Urzo, Peter Kardos & Russell Wiseman
Pages: 1089-1104
Published online: 04 Apr 2018
AbstractforPractical considerations when prescribing a long-acting muscarinic antagonist for patients with COPD | Full Text | References | PDF (445.5 KB)
  • 69 Views
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Original Research

Article
Prediction of severe exacerbations and mortality in COPD: the role of exacerbation history and inspiratory capacity/total lung capacity ratio
João Cardoso, Ricardo Coelho, Carla Rocha, Constança Coelho, Luísa Semedo & A Bugalho Almeida
Pages: 1105-1113
Published online: 05 Apr 2018
AbstractforPrediction of severe exacerbations and mortality in COPD: the role of exacerbation history and inspiratory capacity/total lung capacity ratio | Full Text | References | PDF (553.9 KB)
  • 128 Views
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Article
Geographic variations of the prevalence and distribution of COPD phenotypes in Spain: “the ESPIRAL-ES study”
Bernardino Alcázar-Navarrete, Juan Antonio Trigueros, Juan Antonio Riesco, Anna Campuzano & Joselín Pérez
Pages: 1115-1124
Published online: 20 Oct 2022
AbstractforGeographic variations of the prevalence and distribution of COPD phenotypes in Spain: “the ESPIRAL-ES study” | Full Text | References | PDF (1.9 MB)
  • 83 Views
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Article
Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study
Claus F Vogelmeier, Kenneth R Chapman, Marc Miravitlles, Nicolas Roche, Jørgen Vestbo, Chau Thach, Donald Banerji, Robert Fogel, Francesco Patalano, Petter Olsson, Konstantinos Kostikas & Jadwiga A Wedzicha
Pages: 1125-1134
Published online: 10 Apr 2018
AbstractforExacerbation heterogeneity in COPD: subgroup analyses from the FLAME study | Full Text | References | PDF (593.2 KB)
  • 63 Views
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Article
Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline
Chun-Yu Lo, Hung-Yu Huang, Jung-Ru He, Tzu-Ting Huang, Chih-Chen Heh, Te-Fang Sheng, Kian Fan Chung, Han-Pin Kuo & Chun-Hua Wang
Pages: 1135-1144
Published online: 11 Apr 2018
AbstractforIncreased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline | Full Text | References | PDF (771.9 KB)
  • 95 Views
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Article
Critical regulation of inflammation via class A scavenger receptor
Liang Xie, Qingmin Li, Ran Dong, Kaishun Zhao, Yun Feng, Zhiyao Bao & Min Zhou
Pages: 1145-1155
Published online: 13 Apr 2018
AbstractforCritical regulation of inflammation via class A scavenger receptor | Full Text | References | PDF (1.7 MB)
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Commentary

Article Commentary
Chest pain in patients with COPD: the fascia’s subtle silence
Bruno Bordoni, Fabiola Marelli, Bruno Morabito & Roberto Castagna
Pages: 1157-1165
Published online: 12 Apr 2018
AbstractforChest pain in patients with COPD: the fascia’s subtle silence | Full Text | References | PDF (732.3 KB)
  • 377 Views
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Original Research

Article
The link between chronic obstructive pulmonary disease phenotypes and histological subtypes of lung cancer: a case–control study
Wei Wang, Mengshuang Xie, Shuang Dou, Liwei Cui, Chunyan Zheng & Wei Xiao
Pages: 1167-1175
Published online: 13 Apr 2018
AbstractforThe link between chronic obstructive pulmonary disease phenotypes and histological subtypes of lung cancer: a case–control study | Full Text | References | PDF (337.7 KB)
  • 103 Views
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Article
The association of neuron-derived orphan receptor 1 with pulmonary vascular remodeling in COPD patients
Chang-Guo Wang, Chang Li, Wei Lei, Jun-Hong Jiang, Jian-An Huang & Da-Xiong Zeng
Pages: 1177-1186
Published online: 13 Apr 2018
AbstractforThe association of neuron-derived orphan receptor 1 with pulmonary vascular remodeling in COPD patients | Full Text | References | PDF (1.1 MB)
  • 54 Views
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Article
Randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD
Yasushi Fukushima, Yuji Nakatani, Yumiko Ide, Hisakuni Sekino, Earl St Rose, Shahid Siddiqui, Andrea Maes & Colin Reisner
Pages: 1187-1194
Published online: 13 Apr 2018
AbstractforRandomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD | Full Text | References | PDF (392.1 KB)
  • 62 Views
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Clinical Trial Report

Article
Long-term effects of oxygen-enriched high-flow nasal cannula treatment in COPD patients with chronic hypoxemic respiratory failure
Line Hust Storgaard, Hans-Ulrich Hockey, Birgitte Schantz Laursen & Ulla Møller Weinreich
Pages: 1195-1205
Published online: 16 Apr 2018
AbstractforLong-term effects of oxygen-enriched high-flow nasal cannula treatment in COPD patients with chronic hypoxemic respiratory failure | Full Text | References | PDF (844.1 KB)
  • 575 Views
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Review

Review Article
Prevalence of osteoarthritis in individuals with COPD: a systematic review
Adnan Wshah, Sara JT Guilcher, Roger Goldstein & Dina Brooks
Pages: 1207-1216
Published online: 16 Apr 2018
AbstractforPrevalence of osteoarthritis in individuals with COPD: a systematic review | Full Text | References | PDF (373.6 KB)
  • 266 Views
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Original Research

Article
Bioinformatics-based identification of potential microRNA biomarkers in frequent and non-frequent exacerbators of COPD
Xiao Liu, Jingge Qu, Weixiao Xue, Liangai He, Jun Wang, Xuejiao Xi, Xiaoxia Liu, Yunhong Yin & Yiqing Qu
Pages: 1217-1228
Published online: 20 Oct 2022
AbstractforBioinformatics-based identification of potential microRNA biomarkers in frequent and non-frequent exacerbators of COPD | Full Text | References | PDF (4 MB)
  • 110 Views
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Article
Indacaterol/glycopyrronium reduces the risk of clinically important deterioration after direct switch from baseline therapies in patients with moderate COPD: a post hoc analysis of the CRYSTAL study
Timm Greulich, Konstantinos Kostikas, Mina Gaga, Maryam Aalamian-Mattheis, Nadine S Lossi, Francesco Patalano, Xavier Nunez, Veronica A Pagano, Robert Fogel, Claus F Vogelmeier & Andreas Clemens
Pages: 1229-1237
Published online: 16 Apr 2018
AbstractforIndacaterol/glycopyrronium reduces the risk of clinically important deterioration after direct switch from baseline therapies in patients with moderate COPD: a post hoc analysis of the CRYSTAL study | Full Text | References | PDF (525.1 KB)
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Review

Review Article
Effectiveness of meditative movement on COPD: a systematic review and meta-analysis
Lu-Ling Wu, Zheng-Kun Lin, Hui-Dan Weng, Qiao-Fang Qi, Jun Lu & Kai-Xiong Liu
Pages: 1239-1250
Published online: 17 Apr 2018
AbstractforEffectiveness of meditative movement on COPD: a systematic review and meta-analysis | Full Text | References | PDF (959.8 KB)
  • 353 Views
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Original Research

Article
Heterogeneity of asthma and COPD overlap
Min-Hye Kim, Chin Kook Rhee, Kyungjoo Kim, Sang Hyun Kim, Jung Yeon Lee, Yee Hyung Kim, Kwang Ha Yoo, Young-Joo Cho, Ki-Suck Jung & Jin Hwa Lee
Pages: 1251-1260
Published online: 17 Apr 2018
AbstractforHeterogeneity of asthma and COPD overlap | Full Text | References | PDF (476.4 KB)
  • 75 Views
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Article
The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
Birsen Ocakli, Eylem Acarturk, Emine Aksoy, Sinem Gungor, Fulya Ciyiltepe, Selahattin Oztas, Ipek Ozmen, Meltem Coban Agca, Cuneyt Salturk, Nalan Adiguzel & Zuhal Karakurt
Pages: 1261-1267
Published online: 18 Apr 2018
AbstractforThe impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure | Full Text | References | PDF (323.2 KB)
  • 121 Views
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Article
Static and dynamic hyperinflation during severe acute exacerbations of chronic obstructive pulmonary disease
Wouter H van Geffen & Huib AM Kerstjens
Pages: 1269-1277
Published online: 20 Oct 2022
AbstractforStatic and dynamic hyperinflation during severe acute exacerbations of chronic obstructive pulmonary disease | Full Text | References | PDF (551.4 KB)
  • 140 Views
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Article
Differential anti-inflammatory effects of budesonide and a p38 MAPK inhibitor AZD7624 on COPD pulmonary cells
Andrew Higham, Pradeep Karur, Natalie Jackson, Danen M Cunoosamy, Paul Jansson & Dave Singh
Pages: 1279-1288
Published online: 19 Apr 2018
AbstractforDifferential anti-inflammatory effects of budesonide and a p38 MAPK inhibitor AZD7624 on COPD pulmonary cells | Full Text | References | PDF (1.6 MB)
  • 76 Views
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Article
Influence of deprivation on health care use, health care costs, and mortality in COPD
Peter F Collins, Rebecca J Stratton, Ramesh J Kurukulaaratchy & Marinos Elia
Pages: 1289-1296
Published online: 19 Apr 2018
AbstractforInfluence of deprivation on health care use, health care costs, and mortality in COPD | Full Text | References | PDF (409 KB)
  • 573 Views
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Article
Treatment of exacerbations as a predictor of subsequent outcomes in patients with COPD
Peter MA Calverley, Antonio R Anzueto, Daniel Dusser, Achim Mueller, Norbert Metzdorf & Robert A Wise
Pages: 1297-1308
Published online: 20 Oct 2022
AbstractforTreatment of exacerbations as a predictor of subsequent outcomes in patients with COPD | Full Text | References | PDF (719.2 KB)
  • 138 Views
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Article
Misuse of inhalers among COPD patients in a community hospital in Taiwan
Chi-Yen Liang, Yi-Jen Chen, Shew-Meei Sheu, Ching-Fang Tsai & Wei Chen
Pages: 1309-1316
Published online: 23 Apr 2018
AbstractforMisuse of inhalers among COPD patients in a community hospital in Taiwan | Full Text | References | PDF (314.9 KB)
  • 96 Views
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Article
Dietary resilience in patients with severe COPD at the start of a pulmonary rehabilitation program
Lies ter Beek, Hester van der Vaart, Johan B Wempe, Aliaksandra O Dzialendzik, Jan LN Roodenburg, Cees P van der Schans, Heather H Keller & Harriët Jager-Wittenaar
Pages: 1317-1324
Published online: 23 Apr 2018
AbstractforDietary resilience in patients with severe COPD at the start of a pulmonary rehabilitation program | Full Text | References | PDF (322.9 KB)
  • 184 Views
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Article
The impact of patient education and shared decision making on hospital readmissions for COPD
Ashley W Collinsworth, Rachel M Brown, Cameron S James, Richard H Stanford, Daniel Alemayehu & Elisa L Priest
Pages: 1325-1332
Published online: 24 Apr 2018
AbstractforThe impact of patient education and shared decision making on hospital readmissions for COPD | Full Text | References | PDF (543.5 KB)
  • 770 Views
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Article
Physical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease
Rie Tanaka, Hisatoshi Sugiura, Mitsuhiro Yamada, Tomohiro Ichikawa, Akira Koarai, Naoya Fujino, Satoru Yanagisawa, Katsuhiro Onodera, Tadahisa Numakura, Kei Sato, Yorihiko Kyogoku, Hirohito Sano, Shun Yamanaka, Tatsuma Okazaki, Tsutomu Tamada, Motohiko Miura, Tsuneyuki Takahashi & Masakazu Ichinose
Pages: 1333-1342
Published online: 24 Apr 2018
AbstractforPhysical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease | Full Text | References | PDF (1.6 MB)
  • 88 Views
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Article
Chronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity
Katiany Thays Lopes Zangrando, Renata Trimer, Luiz Carlos Soares de Carvalho Jr, Guilherme Peixoto Tinoco Arêas, Flávia Cristina Rossi Caruso, Ramona Cabiddu, Meliza Goi Roscani, Fabíola Paula Galhardo Rizzatti & Audrey Borghi-Silva
Pages: 1343-1351
Published online: 26 Apr 2018
AbstractforChronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity | Full Text | References | PDF (364.3 KB)
  • 158 Views
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Review

Review Article
Disease burden of COPD in China: a systematic review
Bifan Zhu, Yanfang Wang, Jian Ming, Wen Chen & Luying Zhang
Pages: 1353-1364
Published online: 27 Apr 2018
AbstractforDisease burden of COPD in China: a systematic review | Full Text | References | PDF (813 KB)
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Original Research

Article
Symptomatic burden of COPD for patients receiving dual or triple therapy
Stephanie Chen, Mark Small, Leandro Lindner & Xiao Xu
Pages: 1365-1376
Published online: 27 Apr 2018
AbstractforSymptomatic burden of COPD for patients receiving dual or triple therapy | Full Text | References | PDF (664.4 KB)
  • 95 Views
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Article
Adherence to COPD treatment in Turkey and Saudi Arabia: results of the ADCARE study
Nurdan Kokturk, Mehmet Polatli, I Kivilcim Oguzulgen, Sarfraz Saleemi, Mohammed Al Ghobain, Javed Khan, Adam Doble, Luqman Tariq, Fayaz Aziz & Abdelkader El Hasnaoui
Pages: 1377-1388
Published online: 27 Apr 2018
AbstractforAdherence to COPD treatment in Turkey and Saudi Arabia: results of the ADCARE study | Full Text | References | PDF (531 KB)
  • 227 Views
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Article
The influence of disease severity and lifestyle factors on the peak annual 25(OH)D value of COPD patients
Magnus Kentson, Per Leanderson, Petra Jacobson & Hans Lennart Persson
Pages: 1389-1398
Published online: 27 Apr 2018
AbstractforThe influence of disease severity and lifestyle factors on the peak annual 25(OH)D value of COPD patients | Full Text | References | PDF (691.2 KB)
  • 81 Views
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Article
Validation of the French version of the London Chest Activity of Daily Living scale and the Dyspnea-12 questionnaire
Marc Beaumont, Francis Couturaud, Florence Jego, Romain Pichon, Catherine Le Ber, Loïc Péran, Christophe Rogé, David Renault, Swathi Narayan & Gregory Reychler
Pages: 1399-1405
Published online: 20 Oct 2022
AbstractforValidation of the French version of the London Chest Activity of Daily Living scale and the Dyspnea-12 questionnaire | Full Text | References | PDF (389.5 KB)
  • 186 Views
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Article
Efficacy of tiotropium/olodaterol on lung volume, exercise capacity, and physical activity
Masakazu Ichinose, Yoshiaki Minakata, Takashi Motegi, Jun Ueki, Yasuhiro Gon, Tetsuo Seki, Tatsuhiko Anzai, Shuhei Nakamura & Kazuto Hirata
Pages: 1407-1419
Published online: 01 May 2018
AbstractforEfficacy of tiotropium/olodaterol on lung volume, exercise capacity, and physical activity | Full Text | References | PDF (607 KB)
  • 96 Views
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Article
Quantitative computed tomography features and clinical manifestations associated with the extent of bronchiectasis in patients with moderate-to-severe COPD
So Hyeon Bak, Soohyun Kim, Yoonki Hong, Jeongwon Heo, Myoung-Nam Lim & Woo Jin Kim
Pages: 1421-1431
Published online: 01 May 2018
AbstractforQuantitative computed tomography features and clinical manifestations associated with the extent of bronchiectasis in patients with moderate-to-severe COPD | Full Text | References | PDF (1.7 MB)
  • 73 Views
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Article
Mortality in COPD patients according to clinical phenotypes
Rafael Golpe, María Suárez-Valor, Irene Martín-Robles, Pilar Sanjuán-López, Esteban Cano-Jiménez, Olalla Castro-Añón & Luis A Pérez de Llano
Pages: 1433-1439
Published online: 01 May 2018
AbstractforMortality in COPD patients according to clinical phenotypes | Full Text | References | PDF (774.2 KB)
  • 134 Views
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Article
Validation of exhaled volatile organic compounds analysis using electronic nose as index of COPD severity
Panaiotis Finamore, Claudio Pedone, Simone Scarlata, Alessandra Di Paolo, Simone Grasso, Marco Santonico, Giorgio Pennazza & Raffaele Antonelli Incalzi
Pages: 1441-1448
Published online: 01 May 2018
AbstractforValidation of exhaled volatile organic compounds analysis using electronic nose as index of COPD severity | Full Text | References | PDF (352.8 KB)
  • 99 Views
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Clinical Trial Report

Article
The effect of conjugated linoleic acid on oxidative stress and matrix metalloproteinases 2 and 9 in patients with COPD
Somaieh Matin, Ali Nemati, Hassan Ghobadi, Reza Alipanah-Moghadam & Lotfollah Rezagholizadeh
Pages: 1449-1454
Published online: 03 May 2018
AbstractforThe effect of conjugated linoleic acid on oxidative stress and matrix metalloproteinases 2 and 9 in patients with COPD | Full Text | References | PDF (261.5 KB)
  • 132 Views
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Original Research

Article
Health status in patients with COPD treated with roflumilast: two large noninterventional real-life studies: DINO and DACOTA
Peter Kardos, Ingo Mokros, Rüdiger Sauer & Claus F Vogelmeier
Pages: 1455-1468
Published online: 03 May 2018
AbstractforHealth status in patients with COPD treated with roflumilast: two large noninterventional real-life studies: DINO and DACOTA | Full Text | References | PDF (8 MB)
  • 67 Views
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Article
Tiotropium inhibits methacholine-induced extracellular matrix production via β-catenin signaling in human airway smooth muscle cells
Yating Huo, Lili Guan, Jiawen Xu, Luqian Zhou & Rongchang Chen
Pages: 1469-1481
Published online: 03 May 2018
AbstractforTiotropium inhibits methacholine-induced extracellular matrix production via β-catenin signaling in human airway smooth muscle cells | Full Text | References | PDF (3.4 MB)
  • 57 Views
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Article
Efficacy, safety, and pharmacokinetics of budesonide/formoterol fumarate delivered via metered dose inhaler using innovative co-suspension delivery technology in patients with moderate-to-severe COPD
Edward M Kerwin, Thomas M Siler, Samir Arora, Patrick Darken, Earl Rose St & Colin Reisner
Pages: 1483-1494
Published online: 08 May 2018
AbstractforEfficacy, safety, and pharmacokinetics of budesonide/formoterol fumarate delivered via metered dose inhaler using innovative co-suspension delivery technology in patients with moderate-to-severe COPD | Full Text | References | PDF (769.1 KB)
  • 71 Views
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Article
Severity of acidosis affects long-term survival in COPD patients with hypoxemia after intensive care unit discharge
Sinem Gungor, Feyza Kargin, Ilim Irmak, Fulya Ciyiltepe, Eylem Acartürk Tunçay, Pinar Atagun Guney, Emine Aksoy, Birsen Ocakli, Nalan Adiguzel & Zuhal Karakurt
Pages: 1495-1506
Published online: 09 May 2018
AbstractforSeverity of acidosis affects long-term survival in COPD patients with hypoxemia after intensive care unit discharge | Full Text | References | PDF (968.7 KB)
  • 186 Views
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Article
Gender-specific estimates of COPD prevalence: a systematic review and meta-analysis
Georgios Ntritsos, Jacob Franek, Lazaros Belbasis, Maria A Christou, Georgios Markozannes, Pablo Altman, Robert Fogel, Tobias Sayre, Evangelia E Ntzani & Evangelos Evangelou
Pages: 1507-1514
Published online: 10 May 2018
AbstractforGender-specific estimates of COPD prevalence: a systematic review and meta-analysis | Full Text | References | PDF (447.8 KB)
  • 1196 Views
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Article
Exacerbation recovery patterns in newly diagnosed or maintenance treatment-naïve patients with COPD: secondary analyses of TICARI 1 trial data
David M Mannino, Emmanuelle M Clerisme-Beaty, Joanne Franceschina, Naitee Ting & Nancy K Leidy
Pages: 1515-1525
Published online: 20 Oct 2022
AbstractforExacerbation recovery patterns in newly diagnosed or maintenance treatment-naïve patients with COPD: secondary analyses of TICARI 1 trial data | Full Text | References | PDF (697.3 KB)
  • 61 Views
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Article
Experiences of a health coaching self-management program in patients with COPD: a qualitative content analysis
Lan Wang, Jan Mårtensson, Yue Zhao & Annette Nygårdh
Pages: 1527-1536
Published online: 11 May 2018
AbstractforExperiences of a health coaching self-management program in patients with COPD: a qualitative content analysis | Full Text | References | PDF (325.2 KB)
  • 130 Views
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Article
Chinese version of the severe respiratory insufficiency questionnaire for patients with COPD receiving long-term oxygen therapy
Lili Guan, Jiawen Xu, Weiliang Wu, Jianhua Chen, Xiaoying Li, Bingpeng Guo, Yuqiong Yang, Yating Huo, Luqian Zhou & Rongchang Chen
Pages: 1537-1543
Published online: 11 May 2018
AbstractforChinese version of the severe respiratory insufficiency questionnaire for patients with COPD receiving long-term oxygen therapy | Full Text | References | PDF (286.2 KB)
  • 97 Views
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Article
Respiratory medication used in COPD patients from seven Latin American countries: the LASSYC study
Alejandro Casas, Maria Montes de Oca, Ana MB Menezes, Fernando C Wehrmeister, Maria Victorina Lopez Varela, Laura Mendoza, Larissa Ramírez, Marc Miravitlles & On behalf of the LASSYC team
Pages: 1545-1556
Published online: 11 May 2018
AbstractforRespiratory medication used in COPD patients from seven Latin American countries: the LASSYC study | Full Text | References | PDF (776.9 KB)
  • 135 Views
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Article
The impacts of morning, daytime, and nighttime symptoms on disease burden in real-world patients with COPD
Anna Muñoz, Mark Small, Robert Wood, Anna Ribera & Javier Nuevo
Pages: 1557-1568
Published online: 15 May 2018
AbstractforThe impacts of morning, daytime, and nighttime symptoms on disease burden in real-world patients with COPD | Full Text | References | PDF (1.2 MB)
  • 67 Views
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Article
Reliability and validity of the test of incremental respiratory endurance measures of inspiratory muscle performance in COPD
Magno F Formiga, Kathryn E Roach, Isabel Vital, Gisel Urdaneta, Kira Balestrini, Rafael A Calderon-Candelario, Michael A Campos & Lawrence P Cahalin
Pages: 1569-1576
Published online: 15 May 2018
AbstractforReliability and validity of the test of incremental respiratory endurance measures of inspiratory muscle performance in COPD | Full Text | References | PDF (1,003.7 KB)
  • 148 Views
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Article
The effects of home oxygen therapy on energy metabolism in patients with COPD
Nurcan Kırıcı Berber, Özkan Yetkin, Talat Kılıç, Ilhami Berber & Mehmet Özgel
Pages: 1577-1582
Published online: 15 May 2018
AbstractforThe effects of home oxygen therapy on energy metabolism in patients with COPD | Full Text | References | PDF (945.4 KB)
  • 77 Views
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Article
Clinical characteristics and related risk factors of depression in patients with early COPD
Ji-Hoon Lee, Min A Park, Myung Jae Park & Yong Suk Jo
Pages: 1583-1590
Published online: 15 May 2018
AbstractforClinical characteristics and related risk factors of depression in patients with early COPD | Full Text | References | PDF (669.5 KB)
  • 105 Views
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Article
Effectiveness of a perioperative pulmonary rehabilitation program following coronary artery bypass graft surgery in patients with and without COPD
Jui-O Chen, Jui-Fang Liu, Yu-qi Liu, Yu-Mu Chen, Mei-Lien Tu, Hong-Ren Yu, Meng-Chih Lin, Chiu-Chu Lin & Shih-Feng Liu
Pages: 1591-1597
Published online: 16 May 2018
AbstractforEffectiveness of a perioperative pulmonary rehabilitation program following coronary artery bypass graft surgery in patients with and without COPD | Full Text | References | PDF (459.7 KB)
  • 222 Views
  • 9 CrossRef citations
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Article
Hemoglobin and mortality in patients with COPD: a nationwide population-based cohort study
Seon Cheol Park, Young Sam Kim, Young Ae Kang, Eun Cheol Park, Cheung Soo Shin, Dong Wook Kim & Chin Kook Rhee
Pages: 1599-1605
Published online: 16 May 2018
AbstractforHemoglobin and mortality in patients with COPD: a nationwide population-based cohort study | Full Text | References | PDF (550.3 KB)
  • 147 Views
  • 20 CrossRef citations
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Article
Exercise response to oxygen supplementation is not associated with survival in hypoxemic patients with obstructive lung disease
Ahmed S Sadaka, Andrew J Montgomery, Sahar M Mourad, Michael I Polkey & Nicholas S Hopkinson
Pages: 1607-1612
Published online: 17 May 2018
AbstractforExercise response to oxygen supplementation is not associated with survival in hypoxemic patients with obstructive lung disease | Full Text | References | PDF (652.3 KB)
  • 49 Views
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Article
Distribution and characteristics of COPD phenotypes – results from the Polish sub-cohort of the POPE study
Aleksander Kania, Rafał Krenke, Krzysztof Kuziemski, Małgorzata Czajkowska-Malinowska, Natalia Celejewska-Wójcik, Barbara Kuźnar-Kamińska, Małgorzata Farnik, Juliusz Bokiej, Marta Miszczuk, Iwona Damps-Konstańska, Marcin Grabicki, Marzena Trzaska-Sobczak, Krzysztof Sładek, Halina Batura-Gabryel & Adam Barczyk
Pages: 1613-1621
Published online: 17 May 2018
AbstractforDistribution and characteristics of COPD phenotypes – results from the Polish sub-cohort of the POPE study | Full Text | References | PDF (461.3 KB)
  • 95 Views
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Article
Case-finding for COPD in primary care: a qualitative study of patients’ perspectives
Alexandra Enocson, Kate Jolly, Rachel Elizabeth Jordan, David A Fitzmaurice, SM Greenfield, Peymane Adab & On behalf of the BLISS research team
Pages: 1623-1632
Published online: 17 May 2018
AbstractforCase-finding for COPD in primary care: a qualitative study of patients’ perspectives | Full Text | References | PDF (420.8 KB)
  • 159 Views
  • 7 CrossRef citations
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Article
Evaluation of the psychometric properties of the Early Morning Symptoms of COPD Instrument (EMSCI)
Asha Hareendran, Barry J Make, Erica Zaiser & Esther Garcia Gil
Pages: 1633-1645
Published online: 18 May 2018
AbstractforEvaluation of the psychometric properties of the Early Morning Symptoms of COPD Instrument (EMSCI) | Full Text | References | PDF (742.2 KB)
  • 71 Views
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Article
Emergency department management of acute exacerbations of chronic obstructive pulmonary disease: factors predicting readmission
Wiebke Bartels, Simon Adamson, Lisa Leung, Don D Sin & Stephan F van Eeden
Pages: 1647-1654
Published online: 23 May 2018
AbstractforEmergency department management of acute exacerbations of chronic obstructive pulmonary disease: factors predicting readmission | Full Text | References | PDF (425.8 KB)
  • 189 Views
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Article
Role of diaphragmatic rapid shallow breathing index in predicting weaning outcome in patients with acute exacerbation of COPD
Ahmad Abbas, Sameh Embarak, Mohammad Walaa & Samah Mohamed Lutfy
Pages: 1655-1661
Published online: 21 May 2018
AbstractforRole of diaphragmatic rapid shallow breathing index in predicting weaning outcome in patients with acute exacerbation of COPD | Full Text | References | PDF (760.8 KB)
  • 161 Views
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Article
Is the 6-minute pegboard and ring test valid to evaluate upper limb function in hospitalized patients with acute exacerbation of COPD?
Rosimeire Marcos Felisberto, Cassia Fabiane de Barros, Kelly Cristina Albanezi Nucci, Andre Luis Pereira de Albuquerque, Elaine Paulin, Christina May Moran de Brito & Wellington Pereira Yamaguti
Pages: 1663-1673
Published online: 22 May 2018
AbstractforIs the 6-minute pegboard and ring test valid to evaluate upper limb function in hospitalized patients with acute exacerbation of COPD? | Full Text | References | PDF (1 MB)
  • 204 Views
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Article
A comparison of the assessment of health status between CCQ and CAT in a Chinese COPD clinical population: a cross-sectional analysis
Zijing Zhou, Aiyuan Zhou, Yiyang Zhao, Jiaxi Duan & Ping Chen
Pages: 1675-1682
Published online: 24 May 2018
AbstractforA comparison of the assessment of health status between CCQ and CAT in a Chinese COPD clinical population: a cross-sectional analysis | Full Text | References | PDF (1 MB)
  • 82 Views
  • 9 CrossRef citations
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Article
Association between poor therapy adherence to inhaled corticosteroids and tiotropium and morbidity and mortality in patients with COPD
Kirsten Koehorst-ter Huurne, Catharina GM Groothuis-Oudshoorn, Paul DLPM vanderValk, Kris LL Movig, Job van der Palen & Marjolein Brusse-Keizer
Pages: 1683-1690
Published online: 24 May 2018
AbstractforAssociation between poor therapy adherence to inhaled corticosteroids and tiotropium and morbidity and mortality in patients with COPD | Full Text | References | PDF (315.7 KB)
  • 72 Views
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Article
Blood MCP-1 levels are increased in chronic obstructive pulmonary disease patients with prevalent emphysema
Antonino Di Stefano, Teresa Coccini, Elisa Roda, Cinzia Signorini, Bruno Balbi, Giuseppe Brunetti & Piero Ceriana
Pages: 1691-1700
Published online: 24 May 2018
AbstractforBlood MCP-1 levels are increased in chronic obstructive pulmonary disease patients with prevalent emphysema | Full Text | References | PDF (1.2 MB)
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Clinical Trial Report

Article
Dose–response of an extrafine dry powder inhaler formulation of glycopyrronium bromide: randomized, double-blind, placebo-controlled, dose-ranging study (GlycoNEXT)
Kai M Beeh, Aida Emirova, Hélène Prunier, Debora Santoro & Marie Anna Nandeuil
Pages: 1701-1711
Published online: 20 Oct 2022
AbstractforDose–response of an extrafine dry powder inhaler formulation of glycopyrronium bromide: randomized, double-blind, placebo-controlled, dose-ranging study (GlycoNEXT) | Full Text | References | PDF (1.3 MB)
  • 66 Views
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Original Research

Article
Effectiveness of water-based Liuzijue exercise on respiratory muscle strength and peripheral skeletal muscle function in patients with COPD
Weibing Wu, Xiaodan Liu, Jingxin Liu, Peijun Li & Zhenwei Wang
Pages: 1713-1726
Published online: 25 May 2018
AbstractforEffectiveness of water-based Liuzijue exercise on respiratory muscle strength and peripheral skeletal muscle function in patients with COPD | Full Text | References | PDF (2.6 MB)
  • 192 Views
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Open Access
Article
Prevalence of COPD and respiratory symptoms associated with biomass smoke exposure in a suburban area
Alejandra Ramírez-Venegas, Mónica Velázquez-Uncal, Rosaura Pérez-Hernández, Nicolás Eduardo Guzmán-Bouilloud, Ramcés Falfán-Valencia, María Eugenia Mayar-Maya, Adrian Aranda-Chávez & Raúl H Sansores
Pages: 1727-1734
Published online: 25 May 2018
AbstractforPrevalence of COPD and respiratory symptoms associated with biomass smoke exposure in a suburban area | Full Text | References | PDF (505 KB)
  • 152 Views
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Article
Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study
Yanan Zhang, Jie Qiu, Peng Zhang, Jin Zhang, Min Jiang & Zhanbing Ma
Pages: 1735-1745
Published online: 25 May 2018
AbstractforGenetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study | Full Text | References | PDF (495.8 KB)
  • 91 Views
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Methodology

Article
Chronic obstructive lung disease “expert system”: validation of a predictive tool for assisting diagnosis
Fulvio Braido, Pierachille Santus, Angelo Guido Corsico, Fabiano Di Marco, Giovanni Melioli, Nicola Scichilone & Paolo Solidoro
Pages: 1747-1753
Published online: 28 May 2018
AbstractforChronic obstructive lung disease “expert system”: validation of a predictive tool for assisting diagnosis | Full Text | References | PDF (372.8 KB)
  • 158 Views
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Original Research

Article
Disconnection of pulmonary and systemic arterial stiffness in COPD
Jonathan R Weir-McCall, Patrick SK Liu-Shiu-Cheong, Allan D Struthers, Brian J Lipworth & J Graeme Houston
Pages: 1755-1765
Published online: 28 May 2018
AbstractforDisconnection of pulmonary and systemic arterial stiffness in COPD | Full Text | References | PDF (616 KB)
  • 72 Views
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Article
Acute exacerbation of COPD during pulmonary rehabilitation: outcomes and risk prediction
Bertrand Herer & Thierry Chinet
Pages: 1767-1774
Published online: 20 Oct 2022
AbstractforAcute exacerbation of COPD during pulmonary rehabilitation: outcomes and risk prediction | Full Text | References | PDF (461.7 KB)
  • 113 Views
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Article
Socioeconomic inequality in the use of prescription medications for smoking cessation among patients with COPD: a nationwide study
Sandra Søgaard Tøttenborg, Alice Jessie Clark, Reimar Wernich Thomsen, Søren Paaske Johnsen & Peter Lange
Pages: 1775-1781
Published online: 29 May 2018
AbstractforSocioeconomic inequality in the use of prescription medications for smoking cessation among patients with COPD: a nationwide study | Full Text | References | PDF (257.8 KB)
  • 67 Views
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Article
Functional respiratory imaging: heterogeneity of acute exacerbations of COPD
Wouter H van Geffen, Bita Hajian, Wim Vos, Jan De Backer, Anthony Cahn, Omar S Usmani, Cedric Van Holsbeke, Massimo Pistolesi, Huib AM Kerstjens & Wilfried De Backer
Pages: 1783-1792
Published online: 30 May 2018
AbstractforFunctional respiratory imaging: heterogeneity of acute exacerbations of COPD | Full Text | References | PDF (2.5 MB)
  • 94 Views
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Article
Chronic cough as a novel phenotype of chronic obstructive pulmonary disease
Hyeon-Kyoung Koo, Sung-Woo Park, Jeong-Woong Park, Hye Sook Choi, Tae-Hyung Kim, Hyoung Kyu Yoon, Kwang Ha Yoo, Ki-Suck Jung & Deog Kyeom Kim
Pages: 1793-1801
Published online: 20 Oct 2022
AbstractforChronic cough as a novel phenotype of chronic obstructive pulmonary disease | Full Text | References | PDF (867.7 KB)
  • 212 Views
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Article
Serum levels of trace minerals and heavy metals in severe COPD patients with and without pulmonary hypertension
Selvi Asker, Muntecep Asker, Asli Cilingir Yeltekin, Mehmet Aslan, Bulent Ozbay, Halit Demir & Hakan Turan
Pages: 1803-1808
Published online: 20 Oct 2022
AbstractforSerum levels of trace minerals and heavy metals in severe COPD patients with and without pulmonary hypertension | Full Text | References | PDF (259.1 KB)
  • 87 Views
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Article
Increased urinary l-histidine in patients with asthma–COPD overlap: a pilot study
Jee Youn Oh, Young Seok Lee, Kyung Hoon Min, Gyu Young Hur, Sung Yong Lee, Kyung Ho Kang, Chin Kook Rhee, Seoung Ju Park, Adnan Khan, Jinhyuk Na, Youngja H Park & Jae Jeong Shim
Pages: 1809-1818
Published online: 05 Jun 2018
AbstractforIncreased urinary l-histidine in patients with asthma–COPD overlap: a pilot study | Full Text | References | PDF (1.9 MB)
  • 79 Views
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Article
Long-term safety of tiotropium/olodaterol Respimat® in patients with moderate-to-very severe COPD and renal impairment in the TONADO® studies
Craig LaForce, Eric Derom, Ulrich Bothner, Isabel M Kloer, Matthias Trampisch & Roland Buhl
Pages: 1819-1831
Published online: 01 Jun 2018
AbstractforLong-term safety of tiotropium/olodaterol Respimat® in patients with moderate-to-very severe COPD and renal impairment in the TONADO® studies | Full Text | References | PDF (757.5 KB)
  • 58 Views
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Article
Factors associated with lung cancer in COPD patients
Martin Sandelin, Stéphanie Mindus, Marcus Thuresson, Karin Lisspers, Björn Ställberg, Gunnar Johansson, Kjell Larsson & Christer Janson
Pages: 1833-1839
Published online: 20 Oct 2022
AbstractforFactors associated with lung cancer in COPD patients | Full Text | References | PDF (379.1 KB)
  • 165 Views
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Article
Diversity of respiratory impedance based on quantitative computed tomography in patients with COPD
Yosuke Wada, Yoshiaki Kitaguchi, Masanori Yasuo, Fumika Ueno, Satoshi Kawakami, Kiyoyasu Fukushima, Keisaku Fujimoto & Masayuki Hanaoka
Pages: 1841-1849
Published online: 05 Jun 2018
AbstractforDiversity of respiratory impedance based on quantitative computed tomography in patients with COPD | Full Text | References | PDF (637.7 KB)
  • 88 Views
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Article
BMI–mortality association: shape independent of smoking status but different for chronic lung disease and lung cancer
David Faeh, Marco Kaufmann, Sarah R Haile, Matthias Bopp & On behalf of the Swiss National Cohort Study Group
Pages: 1851-1855
Published online: 06 Jun 2018
AbstractforBMI–mortality association: shape independent of smoking status but different for chronic lung disease and lung cancer | Full Text | References | PDF (564.6 KB)
  • 58 Views
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Article
Evaluation of central and peripheral neuropathy in patients with chronic obstructive pulmonary disease
Yeşim Güzey Aras, Yusuf Aydemir, Belma Doğan Güngen & Adil Can Güngen
Pages: 1857-1862
Published online: 07 Jun 2018
AbstractforEvaluation of central and peripheral neuropathy in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (306.4 KB)
  • 67 Views
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Article
Pharmacists’ training to improve inhaler technique of patients with COPD in Vietnam
Tu-Son Nguyen, Thi Lien Huong Nguyen, Thi Thuy Van Pham, Susan Hua, Quy Chau Ngo & Shu Chuen Li
Pages: 1863-1872
Published online: 11 Jun 2018
AbstractforPharmacists’ training to improve inhaler technique of patients with COPD in Vietnam | Full Text | References | PDF (1.5 MB)
  • 228 Views
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Review

Review Article
Inhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease
Donald P Tashkin & Nicholas J Gross
Pages: 1873-1888
Published online: 12 Jun 2018
AbstractforInhaled glycopyrrolate for the treatment of chronic obstructive pulmonary disease | Full Text | References | PDF (914 KB)
  • 284 Views
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Editorial

Editorial
Are blood eosinophils a prime-time biomarker for COPD management decisions?
Ioanna Tsiligianni & Alan G Kaplan
Pages: 1889-1891
Published online: 12 Jun 2018
First Page PreviewforAre blood eosinophils a prime-time biomarker for COPD management decisions? | Full Text | References | PDF (223.8 KB)
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Original Research

Article
Alternative definitions of chronic bronchitis and their correlation with CT parameters
Jeong Uk Lim, Ji-Hyun Lee, Tae-Hyung Kim, Jae Seung Lee, Sang-Do Lee, Yeon-Mok Oh & Chin Kook Rhee
Pages: 1893-1899
Published online: 20 Oct 2022
AbstractforAlternative definitions of chronic bronchitis and their correlation with CT parameters | Full Text | References | PDF (307.4 KB)
  • 101 Views
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Article
Can CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment?
Nancy K Leidy, Fernando J Martinez, Karen G Malley, David M Mannino, MeiLan K Han, Elizabeth D Bacci, Randall W Brown, Julia F Houfek, Wassim W Labaki, Barry J Make, Catherine A Meldrum, Wilson Quezada, Stephen Rennard, Byron Thomashow & Barbara P Yawn
Pages: 1901-1912
Published online: 13 Jun 2018
AbstractforCan CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment? | Full Text | References | PDF (740.7 KB)
  • 109 Views
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Article
Comorbidities, mortality, and management of chronic obstructive pulmonary disease patients who required admissions to public hospitals in Hong Kong – computerized data collection and analysis
Hok Sum Chan, Fanny Wai San Ko, Johnny Wai Man Chan, Loletta Kit Ying So, David Chi Leung Lam, Veronica Lee Chan, Cheuk Yin Tam & Wai Cho Yu
Pages: 1913-1925
Published online: 13 Jun 2018
AbstractforComorbidities, mortality, and management of chronic obstructive pulmonary disease patients who required admissions to public hospitals in Hong Kong – computerized data collection and analysis | Full Text | References | PDF (520.6 KB)
  • 120 Views
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Article
Prediction models for the development of COPD: a systematic review
Melanie C Matheson, Gayan Bowatte, Jennifer L Perret, Adrian J Lowe, Chamara V Senaratna, Graham L Hall, Nick de Klerk, Louise A Keogh, Christine F McDonald, Nilakshi T Waidyatillake, Peter D Sly, Deborah Jarvis, Michael J Abramson, Caroline J Lodge & Shyamali C Dharmage
Pages: 1927-1935
Published online: 14 Jun 2018
AbstractforPrediction models for the development of COPD: a systematic review | Full Text | References | PDF (399.6 KB)
  • 283 Views
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Article
Significance of prolonged QTc in acute exacerbations of COPD requiring hospitalization
Oliver Van Oekelen, Kristina Vermeersch, Stephanie Everaerts, Bert Vandenberk, Rik Willems & Wim Janssens
Pages: 1937-1947
Published online: 20 Oct 2022
AbstractforSignificance of prolonged QTc in acute exacerbations of COPD requiring hospitalization | Full Text | References | PDF (1 MB)
  • 119 Views
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Article
Satisfaction, preference and error occurrence of three dry powder inhalers as assessed by a cohort naïve to inhaler operation
Kwun Nok Mimi Man, Zhipeng Tian, David Chi-Leung Lam, Jennifer Man Fan Wan & Kian Cheng Tan-Un
Pages: 1949-1963
Published online: 20 Oct 2022
AbstractforSatisfaction, preference and error occurrence of three dry powder inhalers as assessed by a cohort naïve to inhaler operation | Full Text | References | PDF (1 MB)
  • 85 Views
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Article
Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD
Colin Reisner, James Pearle, Edward M Kerwin, Earl St Rose & Patrick Darken
Pages: 1965-1977
Published online: 19 Jun 2018
AbstractforEfficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe COPD | Full Text | References | PDF (701.9 KB)
  • 50 Views
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Article
Clinical characteristics of patients newly diagnosed with COPD by the fixed ratio and lower limit of normal criteria: a cross-sectional analysis of the TargetCOPD trial
Martin R Miller, Shamil Haroon, Rachel E Jordan, Alice J Sitch, Andrew P Dickens, Alexandra Enocson, David A Fitzmaurice & Peymané Adab
Pages: 1979-1986
Published online: 21 Jun 2018
AbstractforClinical characteristics of patients newly diagnosed with COPD by the fixed ratio and lower limit of normal criteria: a cross-sectional analysis of the TargetCOPD trial | Full Text | References | PDF (501.1 KB)
  • 62 Views
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Article
Role of accelerated aging in limb muscle wasting of patients with COPD
Ramzi Lakhdar, Dagmara McGuinness, Ellen M Drost, Paul G Shiels, Ricardo Bastos, William MacNee & Roberto A Rabinovich
Pages: 1987-1998
Published online: 20 Oct 2022
AbstractforRole of accelerated aging in limb muscle wasting of patients with COPD | Full Text | References | PDF (1.8 MB)
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Article
Coronary lesions in patients with COPD (Global Initiative for Obstructive Lung Disease stages I–III) and suspected or confirmed coronary arterial disease
Igor Larchert Mota, Antônio Carlos Sobral Sousa, Maria Luiza Doria Almeida, Enaldo Vieira de Melo, Eduardo José Pereira Ferreira, José Barreto Neto, Carlos José Oliveira Matos, Caio José Coutinho Leal Telino, Maria Júlia Silveira Souto & Joselina Luzia Menezes Oliveira
Pages: 1999-2006
Published online: 26 Jun 2018
AbstractforCoronary lesions in patients with COPD (Global Initiative for Obstructive Lung Disease stages I–III) and suspected or confirmed coronary arterial disease | Full Text | References | PDF (311 KB)
  • 74 Views
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Article
Trends in intensive care unit admissions of COPD patients from 2003 to 2013 in Taiwan
Kuang-Ming Liao, Yi-Chen Chen, Kuo-Chen Cheng, Jhi-Joung Wang & Chung-Han Ho
Pages: 2007-2012
Published online: 26 Jun 2018
AbstractforTrends in intensive care unit admissions of COPD patients from 2003 to 2013 in Taiwan | Full Text | References | PDF (541.9 KB)
  • 115 Views
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Review

Review Article
Exercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review
Yuqin Zeng, Fen Jiang, Yan Chen, Ping Chen & Shan Cai
Pages: 2013-2023
Published online: 26 Jun 2018
AbstractforExercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review | Full Text | References | PDF (301.1 KB)
  • 1726 Views
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Original Research

Article
Clinical impact of nasal budesonide treatment on COPD patients with coexistent rhinitis
Cecilia Calabrese, Adriano Costigliola, Marianna Maffei, Vittorio Simeon, Francesco Perna, Eugenio Tremante, Elena Merola, Carlo Antonio Leone & Andrea Bianco
Pages: 2025-2032
Published online: 27 Jun 2018
AbstractforClinical impact of nasal budesonide treatment on COPD patients with coexistent rhinitis | Full Text | References | PDF (575.8 KB)
  • 65 Views
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Open Access
Article
The Efficiency Index (EFFi), based on volumetric capnography, may allow for simple diagnosis and grading of COPD
Linnea Jarenbäck, Ellen Tufvesson, Jaro Ankerst, Leif Bjermer & Björn Jonson
Pages: 2033-2039
Published online: 27 Jun 2018
AbstractforThe Efficiency Index (EFFi), based on volumetric capnography, may allow for simple diagnosis and grading of COPD | Full Text | References | PDF (738.5 KB)
  • 72 Views
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Article
High prevalence of bronchiectasis in emphysema-predominant COPD patients
Shuang Dou, Chunyan Zheng, Liwei Cui, Mengshuang Xie, Wei Wang, Hui Tian, Kang Li, Kaidi Liu, Xinyu Tian, Xin Wang, Qun Zhang, Xin Ai, Junchao Che, Qixiao Liu, Haijun Li & Wei Xiao
Pages: 2041-2047
Published online: 27 Jun 2018
AbstractforHigh prevalence of bronchiectasis in emphysema-predominant COPD patients | Full Text | References | PDF (514 KB)
  • 137 Views
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Article
The relationship between sleep disturbance and health status in patients with COPD
Woo Ho Ban, Hyonsoo Joo, Jeong Uk Lim, Hyeon Hui Kang, Hwa Sik Moon & Sang Haak Lee
Pages: 2049-2055
Published online: 20 Oct 2022
AbstractforThe relationship between sleep disturbance and health status in patients with COPD | Full Text | References | PDF (927.1 KB)
  • 185 Views
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Article
Relationship between airway obstruction and incidence of metabolic syndrome in Korea: a community-based cohort study
Chi Young Kim, Youngmok Park, Ah Young Leem, Kyung Soo Chung, Ji Ye Jung, Moo Suk Park & Young Sam Kim
Pages: 2057-2063
Published online: 28 Jun 2018
AbstractforRelationship between airway obstruction and incidence of metabolic syndrome in Korea: a community-based cohort study | Full Text | References | PDF (448.5 KB)
  • 82 Views
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Article
Community pharmacists’ knowledge of COPD, and practices and perceptions of medication counseling of COPD patients
Juha Markus Heikkilä, Stina Parkkamäki, Johanna Salimäki, Sari Westermarck & Marika Pohjanoksa-Mäntylä
Pages: 2065-2074
Published online: 03 Jul 2018
AbstractforCommunity pharmacists’ knowledge of COPD, and practices and perceptions of medication counseling of COPD patients | Full Text | References | PDF (295.2 KB)
  • 134 Views
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Article
COPD transitions in health and self-management: service users’ experiences from everyday life
Anne-Grethe Halding, Evy Irene Aarsheim, Nina Marie Dolmen, Aud Jenny Jensen, Sissel Stavøstrand & Ellen Karine Grov
Pages: 2075-2088
Published online: 04 Jul 2018
AbstractforCOPD transitions in health and self-management: service users’ experiences from everyday life | Full Text | References | PDF (312.9 KB)
  • 285 Views
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Review

Review Article
Overuse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice
Didier Cataldo, Eric Derom, Giuseppe Liistro, Eric Marchand, Vincent Ninane, Rudi Peché, Hans Slabbynck, Walter Vincken & Wim Janssens
Pages: 2089-2099
Published online: 05 Jul 2018
AbstractforOveruse of inhaled corticosteroids in COPD: five questions for withdrawal in daily practice | Full Text | References | PDF (493.9 KB)
  • 134 Views
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Letter

Letter
Impact of air pollution on severe acute exacerbation of COPD
Miqdad Haider, Muhammad Nabeel Shafqat & Mariam Zafar
Pages: 2101-2103
Published online: 20 Oct 2022
First Page PreviewforImpact of air pollution on severe acute exacerbation of COPD | Full Text | References | PDF (209.5 KB)
  • 60 Views
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Original Research

Article
The impact of atrial fibrillation in patients with COPD during hospitalization
Chung-Yu Chen & Kuang-Ming Liao
Pages: 2105-2112
Published online: 20 Oct 2022
AbstractforThe impact of atrial fibrillation in patients with COPD during hospitalization | Full Text | References | PDF (390.6 KB)
  • 113 Views
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Article
Feasibility and challenges of using multiple breath washout in COPD
Alan S Bell, Philip J Lawrence, Dave Singh & Alexander Horsley
Pages: 2113-2119
Published online: 10 Jul 2018
AbstractforFeasibility and challenges of using multiple breath washout in COPD | Full Text | References | PDF (621.5 KB)
  • 94 Views
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Article
Development and validation of a predictive model to identify patients at risk of severe COPD exacerbations using administrative claims data
Srinivas Annavarapu, Seth Goldfarb, Melissa Gelb, Chad Moretz, Andrew Renda & Shuchita Kaila
Pages: 2121-2130
Published online: 20 Oct 2022
AbstractforDevelopment and validation of a predictive model to identify patients at risk of severe COPD exacerbations using administrative claims data | Full Text | References | PDF (526.5 KB)
  • 140 Views
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Article
Over-expression of nuclear factor-κB family genes and inflammatory molecules is related to chronic obstructive pulmonary disease
Liting Zhou, Ying Liu, Xin Chen, Shuyue Wang, Hongbo Liu, Tianrong Zhang, Yuezhu Zhang, Qi Xu, Xu Han, Yaming Zhao, Xinyue Song & Lin Ye
Pages: 2131-2138
Published online: 20 Oct 2022
AbstractforOver-expression of nuclear factor-κB family genes and inflammatory molecules is related to chronic obstructive pulmonary disease | Full Text | References | PDF (853.1 KB)
  • 60 Views
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Article
Overall survival of driver mutation-negative non-small cell lung cancer patients with COPD under chemotherapy compared to non-COPD non-small cell lung cancer patients
Jeong Uk Lim, Chang Dong Yeo, Chin Kook Rhee, Yong Hyun Kim, Chan Kwon Park, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Hyoung Kyu Yoon & Sang Haak Lee
Pages: 2139-2146
Published online: 12 Jul 2018
AbstractforOverall survival of driver mutation-negative non-small cell lung cancer patients with COPD under chemotherapy compared to non-COPD non-small cell lung cancer patients | Full Text | References | PDF (557.1 KB)
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Clinical Trial Report

Article
Tiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study
Masakazu Ichinose, Masaharu Nishimura, Manabu Akimoto, Yasuhiro Kurotori, Yihua Zhao, Alberto de la Hoz & Michiaki Mishima
Pages: 2147-2156
Published online: 13 Jul 2018
AbstractforTiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study | Full Text | References | PDF (2.1 MB)
  • 73 Views
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Original Research

Article
T wave peak-to-end interval in COPD
Seda Tural Onur, Samim Emet, Sinem Nedime Sokucu & Imran Onur
Pages: 2157-2162
Published online: 13 Jul 2018
AbstractforT wave peak-to-end interval in COPD | Full Text | References | PDF (638.3 KB)
  • 53 Views
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Article
Long-term safety of bilateral targeted lung denervation in patients with COPD
Arschang Valipour, Sherwin Asadi, Christophe Pison, Marie Jondot, Romain Kessler, Khaled Benneddif, Gaetan Deslee, Margaux Verdier, Dirk-Jan Slebos & Martin Mayse
Pages: 2163-2172
Published online: 16 Jul 2018
AbstractforLong-term safety of bilateral targeted lung denervation in patients with COPD | Full Text | References | PDF (1.2 MB)
  • 156 Views
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Article
Altered community compositions of Proteobacteria in adults with bronchiectasis
Wei-Jie Guan, Jing-Jing Yuan, Hui-Min Li, Yong-Hua Gao, Chun-Lan Chen, Yan Huang, Rong-Chang Chen & Nan-Shan Zhong
Pages: 2173-2182
Published online: 17 Jul 2018
AbstractforAltered community compositions of Proteobacteria in adults with bronchiectasis | Full Text | References | PDF (1.6 MB)
  • 59 Views
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Article
Community-acquired versus hospital-acquired acute kidney injury in patients with acute exacerbation of COPD requiring hospitalization in China
Chang-chun Cao, Da-wei Chen, Jing Li, Meng-qing Ma, Yu-bao Chen, Yi-zhi Cao, Xi Hua, Wei Shao & Xin Wan
Pages: 2183-2190
Published online: 17 Jul 2018
AbstractforCommunity-acquired versus hospital-acquired acute kidney injury in patients with acute exacerbation of COPD requiring hospitalization in China | Full Text | References | PDF (1.3 MB)
  • 74 Views
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Article
Hypercapnic COPD patients and NIV at home: is there any benefit? Using the CAT and BODE index in an effort to prove benefits of NIV in these patients
Andriani Zikyri, Chaido Pastaka & Konstantinos I Gourgoulianis
Pages: 2191-2198
Published online: 17 Jul 2018
AbstractforHypercapnic COPD patients and NIV at home: is there any benefit? Using the CAT and BODE index in an effort to prove benefits of NIV in these patients | Full Text | References | PDF (453.1 KB)
  • 83 Views
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Article
The association between daily exacerbation symptoms and physical activity in patients with chronic obstructive pulmonary disease
Sarah Crook, Gilbert Büsching, Stephan Keusch, Stephan Wieser, Alexander Turk, Martin Frey, Milo A Puhan & Anja Frei
Pages: 2199-2206
Published online: 18 Jul 2018
AbstractforThe association between daily exacerbation symptoms and physical activity in patients with chronic obstructive pulmonary disease | Full Text | References | PDF (1.3 MB)
  • 105 Views
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Article
Relationship between depression and lung function in the general population in Korea: a retrospective cross-sectional study
Youngmok Park, Ji Ye Jung, Young Sam Kim, Kyung Soo Chung, Joo Han Song, Song Yee Kim, Eun Young Kim, Young Ae Kang, Moo Suk Park, Joon Chang & Ah Young Leem
Pages: 2207-2213
Published online: 18 Jul 2018
AbstractforRelationship between depression and lung function in the general population in Korea: a retrospective cross-sectional study | Full Text | References | PDF (343.8 KB)
  • 130 Views
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Article
Clinical and quantitative computed tomography predictors of response to endobronchial lung volume reduction therapy using coils
Konstantina Kontogianni, Kanoe Russell, Ralf Eberhardt, Maren Schuhmann, Claus Peter Heussel, Susan Wood, Felix JF Herth & Daniela Gompelmann
Pages: 2215-2223
Published online: 20 Jul 2018
AbstractforClinical and quantitative computed tomography predictors of response to endobronchial lung volume reduction therapy using coils | Full Text | References | PDF (1.3 MB)
  • 58 Views
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Article
The COPDnet integrated care model
Eleonore H Koolen, Philip J van der Wees, Gert P Westert, Richard Dekhuijzen, Yvonne F Heijdra & Alex J van ’t Hul
Pages: 2225-2235
Published online: 19 Jul 2018
AbstractforThe COPDnet integrated care model | Full Text | References | PDF (470.8 KB)
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Study Protocol

Article
Evaluation of the COPDnet integrated care model in patients with COPD: the study protocol
Eleonore H Koolen, Philip J van der Wees, Gert P Westert, Richard Dekhuijzen, Yvonne F Heijdra & Alex J van ’t Hul
Pages: 2237-2244
Published online: 19 Jul 2018
AbstractforEvaluation of the COPDnet integrated care model in patients with COPD: the study protocol | Full Text | References | PDF (316.7 KB)
  • 85 Views
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Original Research

Article
COPD phenotypes: differences in survival
Julio Hernández Vázquez, Ismael Ali García, Rodrigo Jiménez-García, Alejandro Álvaro Meca, Ana López de Andrés, Carmen Matesanz Ruiz, María Jesús Buendía García & Javier de Miguel Díez
Pages: 2245-2251
Published online: 20 Jul 2018
AbstractforCOPD phenotypes: differences in survival | Full Text | References | PDF (438.8 KB)
  • 82 Views
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Erratum

Correction
Factors associated with appropriate inhaler use in patients with COPD – lessons from the REAL survey [Erratum]
Pages: 2253-2254
Published online: 25 Jul 2018
CitationforFactors associated with appropriate inhaler use in patients with COPD – lessons from the REAL survey [Erratum] | Full Text | PDF (442 KB)
  • 36 Views
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Original Research

Article
Identification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease
Lena Heinbockel, Sebastian Marwitz, Andra B Schromm, Henrik Watz, Christian Kugler, Ole Ammerpohl, Karoline Schnepf, Klaus F Rabe, Daniel Droemann & Torsten Goldmann
Pages: 2255-2259
Published online: 20 Oct 2022
AbstractforIdentification of novel target genes in human lung tissue involved in chronic obstructive pulmonary disease | Full Text | References | PDF (1.3 MB)
  • 72 Views
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Article
Impact of BMI on exacerbation and medical care expenses in subjects with mild to moderate airflow obstruction
Yong Suk Jo, Yee Hyung Kim, Jung Yeon Lee, Kyungjoo Kim, Ki-Suck Jung, Kwang Ha Yoo & Chin Kook Rhee
Pages: 2261-2269
Published online: 27 Jul 2018
AbstractforImpact of BMI on exacerbation and medical care expenses in subjects with mild to moderate airflow obstruction | Full Text | References | PDF (479.9 KB)
  • 65 Views
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Article
The use of a standardized order set reduces systemic corticosteroid dose and length of stay for individuals hospitalized with acute exacerbations of COPD: a cohort study
Swati Gulati, Aline N Zouk, Jonathan P Kalehoff, Christopher S Wren, Peter N Davison, Denay Porter Kirkpatrick, Surya P Bhatt, Mark T Dransfield & James Michael Wells
Pages: 2271-2278
Published online: 27 Jul 2018
AbstractforThe use of a standardized order set reduces systemic corticosteroid dose and length of stay for individuals hospitalized with acute exacerbations of COPD: a cohort study | Full Text | References | PDF (473.6 KB)
  • 96 Views
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Article
Determinants of medical prescriptions for COPD care: an analysis of the EPOCONSUL clinical audit
Jose Luis Lopez-Campos, Bernardino Alcázar Navarrete, Joan B Soriano, Juan J Soler-Cataluña, José Miguel Rodríguez González-Moro, Manuel E Fuentes Ferrer, Myriam Calle Rubio & On behalf of the EPOCONSUL study group
Pages: 2279-2288
Published online: 27 Jul 2018
AbstractforDeterminants of medical prescriptions for COPD care: an analysis of the EPOCONSUL clinical audit | Full Text | References | PDF (646.6 KB)
  • 107 Views
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Article
Symptom-related sputum microbiota in stable chronic obstructive pulmonary disease
Wenqi Diao, Ning Shen, Yipeng Du, John R Erb-Downward, Xiaoyan Sun, Chenxia Guo, Qian Ke, Gary B Huffnagle, Margaret R Gyetko & Bei He
Pages: 2289-2299
Published online: 30 Jul 2018
AbstractforSymptom-related sputum microbiota in stable chronic obstructive pulmonary disease | Full Text | References | PDF (6.5 MB)
  • 65 Views
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Article
COPD affects worker productivity and health care costs
Jeetvan G Patel, Anna D Coutinho, Orsolya E Lunacsek & Anand A Dalal
Pages: 2301-2311
Published online: 30 Jul 2018
AbstractforCOPD affects worker productivity and health care costs | Full Text | References | PDF (1.1 MB)
  • 275 Views
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Article
Morphometric analysis of mitochondria in lymphocytes of patients with exacerbations of chronic obstructive pulmonary disease – pilot study
Adam J Białas, Paweł P Liberski, Anna Zielińska, Anna Kumor-Kisielewska, Karolina Szewczyk, Joanna Miłkowska-Dymanowska, Przemysław Sitarek, Wojciech J Piotrowski & Paweł Górski
Pages: 2313-2318
Published online: 30 Jul 2018
AbstractforMorphometric analysis of mitochondria in lymphocytes of patients with exacerbations of chronic obstructive pulmonary disease – pilot study | Full Text | References | PDF (1 MB)
  • 61 Views
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Review

Review Article
Management of severe COPD exacerbations: focus on beclomethasone dipropionate/formoterol/glycopyrronium bromide
Marco Mantero, Dejan Radovanovic, Pierachille Santus & Francesco Blasi
Pages: 2319-2333
Published online: 30 Jul 2018
AbstractforManagement of severe COPD exacerbations: focus on beclomethasone dipropionate/formoterol/glycopyrronium bromide | Full Text | References | PDF (609.3 KB)
  • 118 Views
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Letter

Letter
Impact of bronchiectasis on the frequency and severity of respiratory exacerbations in COPD
Wassim W Labaki & MeiLan K Han
Pages: 2335-2338
Published online: 31 Jul 2018
First Page PreviewforImpact of bronchiectasis on the frequency and severity of respiratory exacerbations in COPD | Full Text | References | PDF (222.3 KB)
  • 53 Views
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Original Research

Article
PM2.5 downregulates miR-194-3p and accelerates apoptosis in cigarette-inflamed bronchial epithelium by targeting death-associated protein kinase 1
Tianyu Zhou, Yijue Zhong, Yan Hu, Chao Sun, Yunxia Wang & Guangfa Wang
Pages: 2339-2349
Published online: 01 Aug 2018
AbstractforPM2.5 downregulates miR-194-3p and accelerates apoptosis in cigarette-inflamed bronchial epithelium by targeting death-associated protein kinase 1 | Full Text | References | PDF (1.6 MB)
  • 79 Views
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Clinical Trial Report

Article
The accuracy of a handheld “disposable pneumotachograph device” in the spirometric diagnosis of airway obstruction in a Chinese population
Guojun Chen, Longyuan Jiang, Liwen Wang, Wei Zhang, Carlos Castillo & Xiangshao Fang
Pages: 2351-2360
Published online: 02 Aug 2018
AbstractforThe accuracy of a handheld “disposable pneumotachograph device” in the spirometric diagnosis of airway obstruction in a Chinese population | Full Text | References | PDF (1.5 MB)
  • 60 Views
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Original Research

Article
Factors associated with hospital mortality in critically ill patients with exacerbation of COPD
Hamish Brown, Stefan Dodic, Sheen Sern Goh, Cameron Green, Wei C Wang, Sameer Kaul & Ravindranath Tiruvoipati
Pages: 2361-2366
Published online: 02 Aug 2018
AbstractforFactors associated with hospital mortality in critically ill patients with exacerbation of COPD | Full Text | References | PDF (275.6 KB)
  • 238 Views
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Article
Prospective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients
Esra Ertan Yazar, Tevfik Özlü, Muzaffer Sarıaydın, Mahşuk Taylan, Aydanur Ekici, Derya Aydın, İbrahim Güven Coşgun, Nagihan Durmuş Koçak & On behalf of the COHOV Study Group
Pages: 2367-2374
Published online: 10 Aug 2018
AbstractforProspective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients | Full Text | References | PDF (346.1 KB)
  • 90 Views
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Article
Does pulmonary rehabilitation alter patients’ experiences of living with chronic respiratory disease? A qualitative study
Rupert Jones, Herbert Muyinda, Grace Nyakoojo, Bruce Kirenga, Winceslaus Katagira & Jillian Pooler
Pages: 2375-2385
Published online: 08 Aug 2018
AbstractforDoes pulmonary rehabilitation alter patients’ experiences of living with chronic respiratory disease? A qualitative study | Full Text | References | PDF (429.6 KB)
  • 305 Views
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Article
Systematic analysis of transcriptomic profiles of COPD airway epithelium using next-generation sequencing and bioinformatics
Wei-An Chang, Ming-Ju Tsai, Shu-Fang Jian, Chau-Chyun Sheu & Po-Lin Kuo
Pages: 2387-2398
Published online: 10 Aug 2018
AbstractforSystematic analysis of transcriptomic profiles of COPD airway epithelium using next-generation sequencing and bioinformatics | Full Text | References | PDF (3.7 MB)
  • 115 Views
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Article
3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation
Rintaro Onoe, Tsuneo Yamashiro, Hiroshi Handa, Shinya Azagami, Shin Matsuoka, Takeo Inoue, Teruomi Miyazawa & Masamichi Mineshita
Pages: 2399-2407
Published online: 10 Aug 2018
Abstractfor3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation | Full Text | References | PDF (1.5 MB)
  • 62 Views
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Article
A randomized trial of symptom-based management in Japanese patients with COPD
Tomoko Betsuyaku, Motokazu Kato, Keisaku Fujimoto, Akihiro Kobayashi, Tomoyuki Hayamizu, Hideki Hitosugi, Gerald Hagan, Mark H James & Paul W Jones
Pages: 2409-2423
Published online: 13 Aug 2018
AbstractforA randomized trial of symptom-based management in Japanese patients with COPD | Full Text | References | PDF (1.6 MB)
  • 69 Views
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Article
Burden of disease associated with a COPD eosinophilic phenotype
Hector Ortega, Jean-Pierre Llanos, Marie-Hélène Lafeuille, Guillaume Germain, Mei Sheng Duh, Christopher F Bell, Susan R Sama & Beth Hahn
Pages: 2425-2433
Published online: 13 Aug 2018
AbstractforBurden of disease associated with a COPD eosinophilic phenotype | Full Text | References | PDF (1.8 MB)
  • 67 Views
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Article
ACE gene polymorphism is associated with COPD and COPD with pulmonary hypertension: a meta-analysis
Yao Ma, Xiang Tong, Ying Liu, Sitong Liu, Hai Xiong & Hong Fan
Pages: 2435-2446
Published online: 13 Aug 2018
AbstractforACE gene polymorphism is associated with COPD and COPD with pulmonary hypertension: a meta-analysis | Full Text | References | PDF (1.3 MB)
  • 73 Views
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Article
Early and late do-not-resuscitate (DNR) decisions in patients with terminal COPD: a retrospective study in the last year of life
Pin-Kuei Fu, Yu-Chi Tung, Chen-Yu Wang, Sheau-Feng Hwang, Shin-Pin Lin, Chiann-Yi Hsu & Duan-Rung Chen
Pages: 2447-2454
Published online: 14 Aug 2018
AbstractforEarly and late do-not-resuscitate (DNR) decisions in patients with terminal COPD: a retrospective study in the last year of life | Full Text | References | PDF (456.8 KB)
  • 208 Views
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Article
Adherence to GOLD guidelines in real-life COPD management in the Puglia region of Italy
Giuseppe Antonio Palmiotti, Donato Lacedonia, Vito Liotino, Pietro Schino, Francesco Satriano, Pier Luigi Di Napoli, Eugenio Sabato, Vincenzo Mastrosimone, Alfredo Scoditti, Mauro Carone, Elio Costantino, Emanuela Resta, Ettore Attolini & Maria Pia Foschino Barbaro
Pages: 2455-2462
Published online: 15 Aug 2018
AbstractforAdherence to GOLD guidelines in real-life COPD management in the Puglia region of Italy | Full Text | References | PDF (473.2 KB)
  • 140 Views
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Article
Effect of dyspnea on frailty stages and related factors in Taiwanese men with COPD
Pei-Ju Chen, Kuang-Yao Yang, Wann-Cherng Perng, Kuan-Chia Lin & Kwua-Yun Wang
Pages: 2463-2469
Published online: 15 Aug 2018
AbstractforEffect of dyspnea on frailty stages and related factors in Taiwanese men with COPD | Full Text | References | PDF (294.1 KB)
  • 86 Views
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Corrigendum

Correction
Predicting frequent COPD exacerbations using primary care data [Corrigendum]
Page: 2471
Published online: 20 Oct 2022
CitationforPredicting frequent COPD exacerbations using primary care data [Corrigendum] | Full Text | PDF (147.5 KB)
  • 40 Views
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Original Research

Article
Barriers and enablers of COPD telerehabilitation – a frontline staff perspective
Christina Sadolin Damhus, Christina Emme & Henrik Hansen
Pages: 2473-2482
Published online: 17 Aug 2018
AbstractforBarriers and enablers of COPD telerehabilitation – a frontline staff perspective | Full Text | References | PDF (380 KB)
  • 235 Views
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Article
Increased serum IL-17 and decreased serum IL-10 and IL-35 levels correlate with the progression of COPD
Shenghua Jiang, Fenglian Shan, Youwen Zhang, Luning Jiang & Zhaozhong Cheng
Pages: 2483-2494
Published online: 20 Aug 2018
AbstractforIncreased serum IL-17 and decreased serum IL-10 and IL-35 levels correlate with the progression of COPD | Full Text | References | PDF (13.3 MB)
  • 115 Views
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Article
COPD as a risk factor of the complications in lower limb arthroplasty: a patient-matched study
Antonio Klasan, Philipp Dworschak, Thomas Jan Heyse, Steffen Ruchholtz, Peter Alter, Claus Franz Vogelmeier & Patrick Schwarz
Pages: 2495-2499
Published online: 21 Aug 2018
AbstractforCOPD as a risk factor of the complications in lower limb arthroplasty: a patient-matched study | Full Text | References | PDF (307.8 KB)
  • 130 Views
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Article
Social economic costs of COPD in Extremadura (Spain): an observational study
María Merino, Renata Villoro, Álvaro Hidalgo-Vega & Concepción Carmona
Pages: 2501-2514
Published online: 21 Aug 2018
AbstractforSocial economic costs of COPD in Extremadura (Spain): an observational study | Full Text | References | PDF (609.7 KB)
  • 93 Views
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Article
A randomized, open-label, single-visit, crossover study simulating triple-drug delivery with Ellipta compared with dual inhaler combinations in patients with COPD
Job van der Palen, Wendy Moeskops-van Beurden, Carolyn M Dawson, Wai-Yee James, Andrew Preece, Dawn Midwinter, Neil Barnes & Raj Sharma
Pages: 2515-2523
Published online: 21 Aug 2018
AbstractforA randomized, open-label, single-visit, crossover study simulating triple-drug delivery with Ellipta compared with dual inhaler combinations in patients with COPD | Full Text | References | PDF (615.4 KB)
  • 79 Views
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Article
Clinical utility of fractional exhaled nitric oxide and blood eosinophils counts in the diagnosis of asthma–COPD overlap
Yusuke Takayama, Hiroshi Ohnishi, Fumiya Ogasawara, Kosuke Oyama, Tetsuya Kubota & Akihito Yokoyama
Pages: 2525-2532
Published online: 21 Aug 2018
AbstractforClinical utility of fractional exhaled nitric oxide and blood eosinophils counts in the diagnosis of asthma–COPD overlap | Full Text | References | PDF (741.5 KB)
  • 78 Views
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Article
Health effects in COPD smokers who switch to electronic cigarettes: a retrospective-prospective 3-year follow-up
Riccardo Polosa, Jaymin Bhagwanji Morjaria, Umberto Prosperini, Cristina Russo, Alfio Pennisi, Rosario Puleo, Massimo Caruso & Pasquale Caponnetto
Pages: 2533-2542
Published online: 22 Aug 2018
AbstractforHealth effects in COPD smokers who switch to electronic cigarettes: a retrospective-prospective 3-year follow-up | Full Text | References | PDF (929.8 KB)
  • 215 Views
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Article
A novel CT-emphysema index/FEV1 approach of phenotyping COPD to predict mortality
Li-Cher Loh, Choo-Khoon Ong, Hyun-Jung Koo, Sang Min Lee, Jae-Seung Lee, Yeon-Mok Oh, Joon-Beom Seo & Sang-Do Lee
Pages: 2543-2550
Published online: 22 Aug 2018
AbstractforA novel CT-emphysema index/FEV1 approach of phenotyping COPD to predict mortality | Full Text | References | PDF (524.7 KB)
  • 56 Views
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Article
Influence of body mass on predicted values of static hyperinflation in COPD
Peter Alter, Klaus F Rabe, Holger Schulz, Claus F Vogelmeier & Rudolf A Jörres
Pages: 2551-2555
Published online: 23 Aug 2018
AbstractforInfluence of body mass on predicted values of static hyperinflation in COPD | Full Text | References | PDF (912.8 KB)
  • 50 Views
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Clinical Trial Report

Article
Dual bronchodilation vs triple therapy in the “real-life” COPD DACCORD study
Roland Buhl, Carl-Peter Criée, Peter Kardos, Claus F Vogelmeier, Konstantinos Kostikas, Nadine S Lossi & Heinrich Worth
Pages: 2557-2568
Published online: 24 Aug 2018
AbstractforDual bronchodilation vs triple therapy in the “real-life” COPD DACCORD study | Full Text | References | PDF (1.5 MB)
  • 145 Views
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Original Research

Article
IL-26 in the induced sputum is associated with the level of systemic inflammation, lung functions and body weight in COPD patients
Lesia Savchenko, Marina Mykytiuk, Mathieu Cinato, Helene Tronchere, Oxana Kunduzova & Igor Kaidashev
Pages: 2569-2575
Published online: 24 Aug 2018
AbstractforIL-26 in the induced sputum is associated with the level of systemic inflammation, lung functions and body weight in COPD patients | Full Text | References | PDF (614.1 KB)
  • 78 Views
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Article
Prediction of severe acute exacerbation using changes in breathing pattern of COPD patients on home noninvasive ventilation
Sophie Blouet, Jasmine Sutter, Emeline Fresnel, Adrien Kerfourn, Antoine Cuvelier & Maxime Patout
Pages: 2577-2586
Published online: 27 Aug 2018
AbstractforPrediction of severe acute exacerbation using changes in breathing pattern of COPD patients on home noninvasive ventilation | Full Text | References | PDF (2.1 MB)
  • 158 Views
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Review

Review Article
Inhaled corticosteroids for chronic obstructive pulmonary disease: what is their role in therapy?
Donald P Tashkin & Charlie Strange
Pages: 2587-2601
Published online: 27 Aug 2018
AbstractforInhaled corticosteroids for chronic obstructive pulmonary disease: what is their role in therapy? | Full Text | References | PDF (665.2 KB)
  • 631 Views
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Original Research

Article
Relationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea National Health and Nutrition Examination Survey, 2007–2010
Sung Woo Moon, Song Yee Kim, Ji Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Joon Chang, Jun Soo Ro, Yong-Ho Lee & Sang Hoon Lee
Pages: 2603-2611
Published online: 28 Aug 2018
AbstractforRelationship between obstructive lung disease and non-alcoholic fatty liver disease in the Korean population: Korea National Health and Nutrition Examination Survey, 2007–2010 | Full Text | References | PDF (364.8 KB)
  • 117 Views
  • 19 CrossRef citations
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Open Access
Article
Vitamin D status is associated with muscle strength and quality of life in patients with COPD: a seasonal prospective observation study
Emma L Carson, L Kirsty Pourshahidi, Sharon M Madigan, Francina R Baldrick, Martin G Kelly, Eamon Laird, Martin Healy, JJ Strain & Maria S Mulhern
Pages: 2613-2622
Published online: 28 Aug 2018
AbstractforVitamin D status is associated with muscle strength and quality of life in patients with COPD: a seasonal prospective observation study | Full Text | References | PDF (458.3 KB)
  • 98 Views
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Article
Daily duration of long-term oxygen therapy and risk of hospitalization in oxygen-dependent COPD patients
Josefin Sundh, Zainab Ahmadi & Magnus Ekström
Pages: 2623-2628
Published online: 28 Aug 2018
AbstractforDaily duration of long-term oxygen therapy and risk of hospitalization in oxygen-dependent COPD patients | Full Text | References | PDF (532.5 KB)
  • 65 Views
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Article
COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan
Ataru Igarashi, Yoshinosuke Fukuchi, Kazuto Hirata, Masakazu Ichinose, Atsushi Nagai, Masaharu Nishimura, Hajime Yoshisue, Kenichi Ohara & Jean-Bernard Gruenberger
Pages: 2629-2641
Published online: 28 Aug 2018
AbstractforCOPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan | Full Text | References | PDF (659 KB)
  • 112 Views
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Article
Gene expression profile of human lung in a relatively early stage of COPD with emphysema
Ina Jeong, Jae-Hyun Lim, Dong Kyu Oh, Woo Jin Kim & Yeon-Mok Oh
Pages: 2643-2655
Published online: 20 Oct 2022
AbstractforGene expression profile of human lung in a relatively early stage of COPD with emphysema | Full Text | References | PDF (12.2 MB)
  • 198 Views
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Article
Effect of tele–health care on quality of life in patients with severe COPD: a randomized clinical trial
Oliver D Tupper, Thorbjørn L Gregersen, Thomas Ringbaek, Eva Brøndum, Ejvind Frausing, Allan Green & Charlotte S Ulrik
Pages: 2657-2662
Published online: 29 Aug 2018
AbstractforEffect of tele–health care on quality of life in patients with severe COPD: a randomized clinical trial | Full Text | References | PDF (352.2 KB)
  • 215 Views
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Clinical Trial Report

Article
Oropharyngeal swallow physiology and swallowing-related quality of life in underweight patients with concomitant advanced chronic obstructive pulmonary disease
Kendrea L Garand, Charlie Strange, Luca Paoletti, Theresa Hopkins-Rossabi & Bonnie Martin-Harris
Pages: 2663-2671
Published online: 29 Aug 2018
AbstractforOropharyngeal swallow physiology and swallowing-related quality of life in underweight patients with concomitant advanced chronic obstructive pulmonary disease | Full Text | References | PDF (568.2 KB)
  • 235 Views
  • 32 CrossRef citations
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Original Research

Article
A randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD
Wilfried De Backer, Jan De Backer, Wim Vos, Ilse Verlinden, Cedric Van Holsbeke, Johan Clukers, Bita Hajian, Shahid Siddiqui, Martin Jenkins, Colin Reisner & Ubaldo J Martin
Pages: 2673-2684
Published online: 30 Aug 2018
AbstractforA randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using co-suspension delivery technology in patients with COPD | Full Text | References | PDF (1.1 MB)
  • 98 Views
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Article
Determining the minimally important difference in quadriceps strength in individuals with COPD using a fixed dynamometer
Trija Vaidya, Marc Beaumont, Claire de Bisschop, Lucie Bazerque, Camille Le Blanc, Anne Vincent, Hakima Ouksel & Arnaud Chambellan
Pages: 2685-2693
Published online: 30 Aug 2018
AbstractforDetermining the minimally important difference in quadriceps strength in individuals with COPD using a fixed dynamometer | Full Text | References | PDF (544.2 KB)
  • 144 Views
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Review

Review Article
Exhaled nitric oxide in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
Zhiyu Lu, Weina Huang, Linfeng Wang, Ning Xu, Qunli Ding & Chao Cao
Pages: 2695-2705
Published online: 30 Aug 2018
AbstractforExhaled nitric oxide in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis | Full Text | References | PDF (1,014.5 KB)
  • 131 Views
  • 36 CrossRef citations
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Original Research

Article
Cost-effectiveness of roflumilast as an add-on to triple inhaled therapy vs triple inhaled therapy in patients with severe and very severe COPD associated with chronic bronchitis in the UK
Chris Kiff, Sandrine Ruiz, Nebibe Varol, Danny Gibson, Andrew Davies & Debasree Purkayastha
Pages: 2707-2720
Published online: 03 Sep 2018
AbstractforCost-effectiveness of roflumilast as an add-on to triple inhaled therapy vs triple inhaled therapy in patients with severe and very severe COPD associated with chronic bronchitis in the UK | Full Text | References | PDF (1.4 MB)
  • 77 Views
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Article
Neutrophil to lymphocyte ratio is a better indicator of COPD exacerbation severity in neutrophilic endotypes than eosinophilic endotypes
Emine Aksoy, Zuhal Karakurt, Sinem Gungor, Birsen Ocakli, İpek Ozmen, Elif Yildirim, Eylem Tuncay, Meltem Coban Agca, Nezihe Ciftaslan Goksenoglu & Nalan Adigüzel
Pages: 2721-2730
Published online: 04 Sep 2018
AbstractforNeutrophil to lymphocyte ratio is a better indicator of COPD exacerbation severity in neutrophilic endotypes than eosinophilic endotypes | Full Text | References | PDF (1.4 MB)
  • 252 Views
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Original Article

Article
Life-Space mobility and clinical outcomes in COPD
Anand S Iyer, James M Wells, Surya P Bhatt, deNay P Kirkpatrick, Patricia Sawyer, Cynthia J Brown, Richard M Allman, Marie A Bakitas & Mark T Dransfield
Pages: 2731-2738
Published online: 04 Sep 2018
AbstractforLife-Space mobility and clinical outcomes in COPD | Full Text | References | PDF (517.5 KB)
  • 236 Views
  • 18 CrossRef citations
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Review

Review Article
A time for everything and everything in its time – exploring the mechanisms underlying seasonality of COPD exacerbations
Alexander Hicks, Eugene Healy, Natasha Sandeman, Martin Feelisch & Tom Wilkinson
Pages: 2739-2749
Published online: 05 Sep 2018
AbstractforA time for everything and everything in its time – exploring the mechanisms underlying seasonality of COPD exacerbations | Full Text | References | PDF (547.1 KB)
  • 120 Views
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Original Research

Article
A case scenario study for the assessment of physician’s behavior in the management of COPD: the WHY study
Oguz Kilinc, Aylin Konya, Metin Akgun, Esra Uzaslan & Abdullah Sayiner
Pages: 2751-2758
Published online: 20 Oct 2022
AbstractforA case scenario study for the assessment of physician’s behavior in the management of COPD: the WHY study | Full Text | References | PDF (434.4 KB)
  • 67 Views
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Article
Prevalence of undiagnosed COPD in male patients with coronary artery disease: a cross-sectional study in Jordan
Basheer Y Khassawneh, Shaher M Samrah, Mohamad I Jarrah, Rasheed K Ibdah, Ali M Ibnian, Abdelhameed W Almistarehi, Aseel A Zghayer, Saddam I Abuqudairi & Yousef S Khader
Pages: 2759-2766
Published online: 05 Sep 2018
AbstractforPrevalence of undiagnosed COPD in male patients with coronary artery disease: a cross-sectional study in Jordan | Full Text | References | PDF (366.8 KB)
  • 134 Views
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Article
COPD: understanding patients’ adherence to inhaled medications
António Duarte-de-Araújo, Pedro Teixeira, Venceslau Hespanhol & Jaime Correia-de-Sousa
Pages: 2767-2773
Published online: 06 Sep 2018
AbstractforCOPD: understanding patients’ adherence to inhaled medications | Full Text | References | PDF (267.4 KB)
  • 395 Views
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Article
Blood eosinophils and inhaled corticosteroids in patients with COPD: systematic review and meta-analysis
Shih-Lung Cheng
Pages: 2775-2784
Published online: 06 Sep 2018
AbstractforBlood eosinophils and inhaled corticosteroids in patients with COPD: systematic review and meta-analysis | Full Text | References | PDF (585.5 KB)
  • 208 Views
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Article
Functional performance in patients with COPD: association with treatment regimen, GOLD group, lung function, and symptom burden in a cross-sectional study
Bo Ding, Davneet Judge, Mark Small, Nawal Bent-Ennakhil & Shahid Siddiqui
Pages: 2785-2796
Published online: 07 Sep 2018
AbstractforFunctional performance in patients with COPD: association with treatment regimen, GOLD group, lung function, and symptom burden in a cross-sectional study | Full Text | References | PDF (3.3 MB)
  • 79 Views
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Article
Prevalence of smoking in a psychiatric hospital and its relationship with respiratory symptoms and the prevalence of COPD
Luis Lores, Alfonso Monje, Manel Bergada, Elisabeth Arellano, Julian Rodríguez-Larrea & Marc Miravitlles
Pages: 2797-2804
Published online: 07 Sep 2018
AbstractforPrevalence of smoking in a psychiatric hospital and its relationship with respiratory symptoms and the prevalence of COPD | Full Text | References | PDF (367 KB)
  • 84 Views
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Review

Review Article
New developments in optimizing bronchodilator treatment of COPD: a focus on glycopyrrolate/formoterol combination formulated by co-suspension delivery technology
Anthony D D’Urzo, Mario Cazzola, Nicola A Hanania, Roland Buhl & M Reza Maleki-Yazdi
Pages: 2805-2819
Published online: 07 Sep 2018
AbstractforNew developments in optimizing bronchodilator treatment of COPD: a focus on glycopyrrolate/formoterol combination formulated by co-suspension delivery technology | Full Text | References | PDF (441.2 KB)
  • 74 Views
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Original Research

Article
Nucleosides isolated from Ophiocordyceps sinensis inhibit cigarette smoke extract-induced inflammation via the SIRT1–nuclear factor-κB/p65 pathway in RAW264.7 macrophages and in COPD mice
Xiao Sun, Zhonghua Dong, Nan Li, Xiuli Feng, Yan Liu, Ang Li, Xiaosong Zhu, Chunyan Li & Zhongxi Zhao
Pages: 2821-2832
Published online: 10 Sep 2018
AbstractforNucleosides isolated from Ophiocordyceps sinensis inhibit cigarette smoke extract-induced inflammation via the SIRT1–nuclear factor-κB/p65 pathway in RAW264.7 macrophages and in COPD mice | Full Text | References | PDF (1.8 MB)
  • 116 Views
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Article
A comparative study of the five-repetition sit-to-stand test and the 30-second sit-to-stand test to assess exercise tolerance in COPD patients
Qin Zhang, Yan-xia Li, Xue-lian Li, Yan Yin, Rui-lan Li, Xin Qiao, Wei Li, Hai-feng Ma, Wen-hui Ma, Yu-feng Han, Guang-qiao Zeng, Qiu-yue Wang, Jian Kang & Gang Hou
Pages: 2833-2839
Published online: 10 Sep 2018
AbstractforA comparative study of the five-repetition sit-to-stand test and the 30-second sit-to-stand test to assess exercise tolerance in COPD patients | Full Text | References | PDF (582.6 KB)
  • 957 Views
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Article
Instability of nocturnal parasympathetic nerve function in patients with chronic lung disease with or without nocturnal desaturation
Keisaku Fujimoto, Haruna Yamazaki & Akikazu Uematsu
Pages: 2841-2848
Published online: 11 Sep 2018
AbstractforInstability of nocturnal parasympathetic nerve function in patients with chronic lung disease with or without nocturnal desaturation | Full Text | References | PDF (519.3 KB)
  • 49 Views
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Article
The role of CAT in evaluating the response to treatment of patients with AECOPD
Aiyuan Zhou, Zijing Zhou, Yating Peng, Yiyang Zhao, Jiaxi Duan & Ping Chen
Pages: 2849-2858
Published online: 20 Oct 2022
AbstractforThe role of CAT in evaluating the response to treatment of patients with AECOPD | Full Text | References | PDF (1.1 MB)
  • 158 Views
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Article
Health characteristics of patients with asthma, COPD and asthma–COPD overlap in the NHANES database
Jean-Pierre Llanos, Hector Ortega, Guillaume Germain, Mei Sheng Duh, Marie-Helene Lafeuille, Sean Tiggelaar, Christopher F Bell & Beth Hahn
Pages: 2859-2868
Published online: 20 Oct 2022
AbstractforHealth characteristics of patients with asthma, COPD and asthma–COPD overlap in the NHANES database | Full Text | References | PDF (850.3 KB)
  • 183 Views
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Article
Sociodemographic and clinical factors affecting the quality of life of patients with chronic obstructive pulmonary disease
Joanna Rosińczuk, Maria Przyszlak & Izabella Uchmanowicz
Pages: 2869-2882
Published online: 12 Sep 2018
AbstractforSociodemographic and clinical factors affecting the quality of life of patients with chronic obstructive pulmonary disease | Full Text | References | PDF (520.4 KB)
  • 206 Views
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Article
Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function
Kylie BR Belchamber, Catherine MR Thomas, Amy E Dunne, Peter J Barnes & Louise E Donnelly
Pages: 2883-2897
Published online: 17 Sep 2018
AbstractforComparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function | Full Text | References | PDF (1.7 MB)
  • 82 Views
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Article
The association between COPD and outcomes of patients with advanced chronic kidney disease
Chih-Cheng Lai, Che-Hsiung Wu, Ya-Hui Wang, Cheng-Yi Wang, Vin-Cent Wu & Likwang Chen
Pages: 2899-2905
Published online: 17 Sep 2018
AbstractforThe association between COPD and outcomes of patients with advanced chronic kidney disease | Full Text | References | PDF (410.6 KB)
  • 207 Views
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Article
Proton pump inhibitors use is associated with a lower risk of acute exacerbation and mortality in patients with coexistent COPD and GERD
Vincent Yi-Fong Su, Han-Fang Liao, Diahn-Warng Perng, Yueh-Ching Chou, Chia-Chen Hsu, Chia-Lin Chou, Yuh-Lih Chang, Jiin-Cherng Yen, Tzeng-Ji Chen & Ting-Chun Chou
Pages: 2907-2915
Published online: 19 Sep 2018
AbstractforProton pump inhibitors use is associated with a lower risk of acute exacerbation and mortality in patients with coexistent COPD and GERD | Full Text | References | PDF (454.7 KB)
  • 107 Views
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Article
Effect of background long-acting beta2-agonist therapy on the efficacy and safety of a novel, nebulized glycopyrrolate in subjects with moderate-to-very-severe COPD
Edward M Kerwin, Robert Tosiello, Barry Price, Shahin Sanjar & Thomas Goodin
Pages: 2917-2929
Published online: 19 Sep 2018
AbstractforEffect of background long-acting beta2-agonist therapy on the efficacy and safety of a novel, nebulized glycopyrrolate in subjects with moderate-to-very-severe COPD | Full Text | References | PDF (2.7 MB)
  • 53 Views
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Article
The role of plasma N-terminal brain natriuretic pro-peptide in diagnosing elderly patients with acute exacerbation of COPD concurrent with left heart failure
Xuxue Guo, Hanxiang Nie, Qianhui Chen, Shuo Chen, Nishan Deng, Ruiyun Li, Xuhong Ding, Suping Hu & Ailing Wang
Pages: 2931-2940
Published online: 20 Oct 2022
AbstractforThe role of plasma N-terminal brain natriuretic pro-peptide in diagnosing elderly patients with acute exacerbation of COPD concurrent with left heart failure | Full Text | References | PDF (1.1 MB)
  • 49 Views
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Article
A comparative analysis of errors in inhaler technique among COPD versus asthma patients
Birsen Ocakli, Ipek Ozmen, Eylem Acartürk Tunçay, Sinem Gungor, Hilal Altinoz, Nalan Adiguzel, Zafer Ali Sak, Gokay Gungor, Zuhal Karakurt & Peri Arbak
Pages: 2941-2947
Published online: 24 Sep 2018
AbstractforA comparative analysis of errors in inhaler technique among COPD versus asthma patients | Full Text | References | PDF (287.2 KB)
  • 224 Views
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Article
The impact of 2011 and 2017 Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guidelines on allocation and pharmacological management of patients with COPD in Taiwan: Taiwan Obstructive Lung Disease (TOLD) study
Meng-Jer Hsieh, Shu-Yi Huang, Tsung-Ming Yang, Chi-Wei Tao, Shih-Lung Cheng, Chao-Hsien Lee, Ping-Hung Kuo, Yao-Kuang Wu, Ning-Hung Chen, Wu-Huei Hsu, Jeng-Yuan Hsu, Ming-Shian Lin, Chin-Chou Wang, Yu-Feng Wei & Ying-Huang Tsai
Pages: 2949-2959
Published online: 25 Sep 2018
AbstractforThe impact of 2011 and 2017 Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guidelines on allocation and pharmacological management of patients with COPD in Taiwan: Taiwan Obstructive Lung Disease (TOLD) study | Full Text | References | PDF (498.9 KB)
  • 148 Views
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Article
Bispectral index in hypercapnic encephalopathy associated with COPD exacerbation: a pilot study
Roberto Chalela, Lluis Gallart, Sergi Pascual-Guardia, Antonio Sancho-Muñoz, Joaquim Gea & Mauricio Orozco-Levi
Pages: 2961-2967
Published online: 26 Sep 2018
AbstractforBispectral index in hypercapnic encephalopathy associated with COPD exacerbation: a pilot study | Full Text | References | PDF (681.5 KB)
  • 116 Views
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Article
Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA
Brian J Lipworth, David J Collier, Yasuhiro Gon, Nanshan Zhong, Koichi Nishi, Rongchang Chen, Samir Arora, Andrea Maes, Shahid Siddiqui, Colin Reisner & Ubaldo J Martin
Pages: 2969-2984
Published online: 26 Sep 2018
AbstractforImproved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA | Full Text | References | PDF (547.2 KB)
  • 97 Views
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Article
1H-NMR-based metabolic profiling of healthy individuals and high-resolution CT-classified phenotypes of COPD with treatment of tiotropium bromide
Li-Chuan Tan, Wen-Jie Yang, Wei-Ping Fu, Ping Su, Jing-Kui Shu & Lu-Ming Dai
Pages: 2985-2997
Published online: 27 Sep 2018
Abstractfor1H-NMR-based metabolic profiling of healthy individuals and high-resolution CT-classified phenotypes of COPD with treatment of tiotropium bromide | Full Text | References | PDF (4.3 MB)
  • 60 Views
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Article
Longitudinal stability of blood eosinophil count strata in the COPD COSYCONET cohort
Timm Greulich, Sina Mager, Tanja Lucke, Andreas Rembert Koczulla, Robert Bals, Sebastian Fähndrich, Rudolf A Jörres, Peter Alter, Anne Kirsten, Claus Franz Vogelmeier & Henrik Watz
Pages: 2999-3002
Published online: 28 Sep 2018
First Page PreviewforLongitudinal stability of blood eosinophil count strata in the COPD COSYCONET cohort | Full Text | References | PDF (319.1 KB)
  • 52 Views
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Editorial

Editorial
Current appraisal of single inhaler triple therapy in COPD
Brian Lipworth, Chris RuiWen Kuo & Sunny Jabbal
Pages: 3003-3009
Published online: 28 Sep 2018
AbstractforCurrent appraisal of single inhaler triple therapy in COPD | Full Text | References | PDF (2.6 MB)
  • 212 Views
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Original Research

Article
Comparison of the clinical characteristics and comprehensive assessments of the 2011 and 2017 GOLD classifications for patients with COPD in China
Yu-He Hu, Zhen-Yu Liang, Li-Mei Xu, Wen-Hui Xu, Hao Liao, Rui Li, Kai Wang, Ying Xu, Chun-Quan Ou & Xin Chen
Pages: 3011-3019
Published online: 28 Sep 2018
AbstractforComparison of the clinical characteristics and comprehensive assessments of the 2011 and 2017 GOLD classifications for patients with COPD in China | Full Text | References | PDF (556.2 KB)
  • 67 Views
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Article
Women manifest more severe COPD symptoms across the life course
Dawn L DeMeo, Sreeram Ramagopalan, Abhishek Kavati, Ashok Vegesna, Meilan K Han, Anthony Yadao, Teresa K Wilcox, Barry J Make & On behalf of COPDGene Investigators
Pages: 3021-3029
Published online: 01 Oct 2018
AbstractforWomen manifest more severe COPD symptoms across the life course | Full Text | References | PDF (1.5 MB)
  • 296 Views
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Article
Significances of spirometry and impulse oscillometry for detecting small airway disorders assessed with endobronchial optical coherence tomography in COPD
Zhu-Quan Su, Wei-Jie Guan, Shi-Yue Li, Ming Ding, Yu Chen, Mei Jiang, Xiao-Bo Chen, Chang-Hao Zhong, Chun-Li Tang & Nan-Shan Zhong
Pages: 3031-3044
Published online: 01 Oct 2018
AbstractforSignificances of spirometry and impulse oscillometry for detecting small airway disorders assessed with endobronchial optical coherence tomography in COPD | Full Text | References | PDF (4.1 MB)
  • 166 Views
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Article
Eosinophil counts in first COPD hospitalizations: a comparison of health service utilization
Maryse Bélanger, Simon Couillard, Josiane Courteau, Pierre Larivée, Thomas G Poder, Nathalie Carrier, Kim Girard, Felix-Antoine Vézina & Alain Vanasse
Pages: 3045-3054
Published online: 01 Oct 2018
AbstractforEosinophil counts in first COPD hospitalizations: a comparison of health service utilization | Full Text | References | PDF (781.5 KB)
  • 71 Views
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Article
Validity of ICD9-CM codes to diagnose chronic obstructive pulmonary disease from National Health Insurance claim data in Taiwan
Te-Wei Ho, Sheng-Yuan Ruan, Chun-Ta Huang, Yi-Ju Tsai, Feipei Lai & Chong-Jen Yu
Pages: 3055-3063
Published online: 02 Oct 2018
AbstractforValidity of ICD9-CM codes to diagnose chronic obstructive pulmonary disease from National Health Insurance claim data in Taiwan | Full Text | References | PDF (494.1 KB)
  • 199 Views
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Article
Eosinophil counts in first COPD hospitalizations: a 1-year cost analysis in Quebec, Canada
Thomas G Poder, Nathalie Carrier, Maryse Bélanger, Simon Couillard, Josiane Courteau, Pierre Larivée & Alain Vanasse
Pages: 3065-3076
Published online: 08 Oct 2018
AbstractforEosinophil counts in first COPD hospitalizations: a 1-year cost analysis in Quebec, Canada | Full Text | References | PDF (533.7 KB)
  • 68 Views
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Article
Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
Juwhan Choi, Jee Youn Oh, Young Seok Lee, Gyu Young Hur, Sung Yong Lee, Jae Jeong Shim, Kyung Ho Kang & Kyung Hoon Min
Pages: 3077-3083
Published online: 02 Oct 2018
AbstractforPseudomonas aeruginosa infection increases the readmission rate of COPD patients | Full Text | References | PDF (354.4 KB)
  • 122 Views
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Article
Use of medicines and health services for chronic obstructive pulmonary disease among a cohort of Australians over 50 years
Renly Lim, Mhairi Kerr & Elizabeth E Roughead
Pages: 3085-3093
Published online: 04 Oct 2018
AbstractforUse of medicines and health services for chronic obstructive pulmonary disease among a cohort of Australians over 50 years | Full Text | References | PDF (308.9 KB)
  • 92 Views
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Article
Enlightening chronic obstructive pulmonary disease through patients’ and caregivers’ narratives
Valeria Gatti, Paolo Banfi, Stefano Centanni, Salvatore D’Antonio, Saffi Giustini, Alessio Piraino, Marco Zibellini & Maria Giulia Marini
Pages: 3095-3105
Published online: 05 Oct 2018
AbstractforEnlightening chronic obstructive pulmonary disease through patients’ and caregivers’ narratives | Full Text | References | PDF (301.4 KB)
  • 87 Views
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Clinical Trial Report

Article
Effects of YuPingFeng granules on acute exacerbations of COPD: a randomized, placebo-controlled study
Jinfang Ma, Jinping Zheng, Nanshan Zhong, Chunxue Bai, Haoyan Wang, Juan Du, Fenglei Li, Yanwei Chen, Zhe Shi, Xin Li & Pingyan Chen
Pages: 3107-3114
Published online: 04 Oct 2018
AbstractforEffects of YuPingFeng granules on acute exacerbations of COPD: a randomized, placebo-controlled study | Full Text | References | PDF (586.8 KB)
  • 108 Views
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Review

Review Article
LABA/LAMA fixed-dose combinations in patients with COPD: a systematic review
Paola Rogliani, Luigino Calzetta, Fulvio Braido, Mario Cazzola, Enrico Clini, Girolamo Pelaia, Andrea Rossi, Nicola Scichilone & Fabiano Di Marco
Pages: 3115-3130
Published online: 04 Oct 2018
AbstractforLABA/LAMA fixed-dose combinations in patients with COPD: a systematic review | Full Text | References | PDF (499.2 KB)
  • 249 Views
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Original Research

Article
Utility of ultrasound assessment of diaphragmatic function before and after pulmonary rehabilitation in COPD patients
Claudia Crimi, Enrico Heffler, Teresa Augelletti, Raffaele Campisi, Alberto Noto, Carlo Vancheri & Nunzio Crimi
Pages: 3131-3139
Published online: 08 Oct 2018
AbstractforUtility of ultrasound assessment of diaphragmatic function before and after pulmonary rehabilitation in COPD patients | Full Text | References | PDF (840.7 KB)
  • 241 Views
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Article
Effects of a single long-acting muscarinic antagonist agent and a long-acting muscarinic antagonist/long-acting β2-adrenoceptor agonist combination on lung function and symptoms in untreated COPD patients in Japan
Hideyasu Yamada, Norihito Hida & Nobuyuki Hizawa
Pages: 3141-3147
Published online: 08 Oct 2018
AbstractforEffects of a single long-acting muscarinic antagonist agent and a long-acting muscarinic antagonist/long-acting β2-adrenoceptor agonist combination on lung function and symptoms in untreated COPD patients in Japan | Full Text | References | PDF (636.8 KB)
  • 42 Views
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Article
COPD assessment test and FEV1: do they predict oxygen uptake in COPD?
Luiz Carlos S Carvalho-Jr, Renata Trimer, Guilherme PT Arêas, Flávia CR Caruso, Katiany TL Zangrando, Soraia Pilon Jürgensen, José C Bonjorno Jr, Cláudio Ricardo de Oliveira, Ramona Cabiddu, Renata G Mendes & Audrey Borghi-Silva
Pages: 3149-3156
Published online: 08 Oct 2018
AbstractforCOPD assessment test and FEV1: do they predict oxygen uptake in COPD? | Full Text | References | PDF (454.4 KB)
  • 127 Views
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Article
Increased serum levels of S100A1, ZAG, and adiponectin in cachectic patients with COPD
Amin Mokari-Yamchi, Akbar Sharifi & Sorayya Kheirouri
Pages: 3157-3163
Published online: 08 Oct 2018
AbstractforIncreased serum levels of S100A1, ZAG, and adiponectin in cachectic patients with COPD | Full Text | References | PDF (519.5 KB)
  • 88 Views
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Review

Review Article
Autophagy, selective autophagy, and necroptosis in COPD
Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu & Yasuhiro Gon
Pages: 3165-3172
Published online: 09 Oct 2018
AbstractforAutophagy, selective autophagy, and necroptosis in COPD | Full Text | References | PDF (1.5 MB)
  • 85 Views
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Original Research

Article
Differential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients
Luca Ricciardi, Jessica Dal Col, Paolo Casolari, Domenico Memoli, Valeria Conti, Alessandro Vatrella, Becky M Vonakis, Alberto Papi, Gaetano Caramori & Cristiana Stellato
Pages: 3173-3190
Published online: 12 Oct 2018
AbstractforDifferential expression of RNA-binding proteins in bronchial epithelium of stable COPD patients | Full Text | References | PDF (5.7 MB)
  • 98 Views
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Article
Glucagon-like peptide-1 receptor (GLP-1R) signaling ameliorates dysfunctional immunity in COPD patients
Jingwen Huang, Huahua Yi, Chunliu Zhao, Yifan Zhang, Liying Zhu, Bing Liu, Ping He & Min Zhou
Pages: 3191-3202
Published online: 09 Oct 2018
AbstractforGlucagon-like peptide-1 receptor (GLP-1R) signaling ameliorates dysfunctional immunity in COPD patients | Full Text | References | PDF (1.8 MB)
  • 150 Views
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Review

Review Article
Comparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis
Mohamed Ismail Abdul Aziz, Ling Eng Tan, David Bin-Chia Wu, Fiona Pearce, Gerald Seng Wee Chua, Liang Lin, Ping-Tee Tan & Kwong Ng
Pages: 3203-3231
Published online: 09 Oct 2018
AbstractforComparative efficacy of inhaled medications (ICS/LABA, LAMA, LAMA/LABA and SAMA) for COPD: a systematic review and network meta-analysis | Full Text | References | PDF (1.6 MB)
  • 335 Views
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Original Research

Article
Which GOLD B patients progress to GOLD D with the new classification?
Hye Sook Choi, Ju Ock Na, Jong Deog Lee, Kyeong-Cheol Shin, Chin Kook Rhee, Yong Il Hwang, Seong Yong Lim, Kwang Ha Yoo, Ki Suck Jung & Yong Bum Park
Pages: 3233-3241
Published online: 12 Oct 2018
AbstractforWhich GOLD B patients progress to GOLD D with the new classification? | Full Text | References | PDF (562.3 KB)
  • 60 Views
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Article
Whole-body vibration training – better care for COPD patients: a systematic review and meta-analysis
Jian Zhou, Long Pang, Nan Chen, Zihuai Wang, Chengdi Wang, Yang Hai, Mengyuan Lyu, Hongjin Lai & Feng Lin
Pages: 3243-3254
Published online: 10 Oct 2018
AbstractforWhole-body vibration training – better care for COPD patients: a systematic review and meta-analysis | Full Text | References | PDF (2 MB)
  • 130 Views
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Open Access
Article
Validation of ACCESS: an automated tool to support self-management of COPD exacerbations
Lonneke M Boer, Maarten van der Heijden, Nathalie ME van Kuijk, Peter JF Lucas, Jan H Vercoulen, Willem JJ Assendelft, Erik W Bischoff & Tjard R Schermer
Pages: 3255-3267
Published online: 10 Oct 2018
AbstractforValidation of ACCESS: an automated tool to support self-management of COPD exacerbations | Full Text | References | PDF (1.1 MB)
  • 125 Views
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Open Access
Article
Gender difference on the knowledge, attitude, and practice of COPD diagnosis and treatment: a national, multicenter, cross-sectional survey in China
Guohua Jia, Ming Lu, Rui Wu, Yahong Chen & Wanzhen Yao
Pages: 3269-3280
Published online: 10 Oct 2018
AbstractforGender difference on the knowledge, attitude, and practice of COPD diagnosis and treatment: a national, multicenter, cross-sectional survey in China | Full Text | References | PDF (412.2 KB)
  • 243 Views
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Article
Forced oscillation technique for early detection of the effects of smoking and COPD: contribution of fractional-order modeling
Caroline Oliveira Ribeiro, Alvaro Camilo Dias Faria, Agnaldo José Lopes & Pedro Lopes de Melo
Pages: 3281-3295
Published online: 11 Oct 2018
AbstractforForced oscillation technique for early detection of the effects of smoking and COPD: contribution of fractional-order modeling | Full Text | References | PDF (3 MB)
  • 111 Views
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Article
A systematic diagnostic evaluation combined with an internet-based self-management support system for patients with asthma or COPD
Amanda R van Buul, Thomas S Wildschut, Tobias N Bonten, Marise J Kasteleyn, Annelies M Slats, Niels H Chavannes & Christian Taube
Pages: 3297-3306
Published online: 12 Oct 2018
AbstractforA systematic diagnostic evaluation combined with an internet-based self-management support system for patients with asthma or COPD | Full Text | References | PDF (433.8 KB)
  • 55 Views
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Article
Prevalence of malnutrition in COPD and its relationship with the parameters related to disease severity
Burak Mete, Erkan Pehlivan, Gazi Gülbaş & Hakan Günen
Pages: 3307-3312
Published online: 11 Oct 2018
AbstractforPrevalence of malnutrition in COPD and its relationship with the parameters related to disease severity | Full Text | References | PDF (328.1 KB)
  • 767 Views
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Article
The impact on health status in short- and long-terms of a novel and non-orthodox real-world COPD rehabilitation effort in rural India: an appraisal
Parthasarathi Bhattacharyya, Rupak Ghosh, Dipanjan Saha, Bodhisattwa Chakraborty, Pallav Bhattacharyya, Madan Sarma, Saibal Mazumdar, Kajal Chatterjee & Avijit Chowdhury
Pages: 3313-3319
Published online: 15 Oct 2018
AbstractforThe impact on health status in short- and long-terms of a novel and non-orthodox real-world COPD rehabilitation effort in rural India: an appraisal | Full Text | References | PDF (407.1 KB)
  • 108 Views
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Article
Validation of lung density indices by cardiac CT for quantification of lung emphysema
Andreas Ronit, Thomas Kristensen, Yunus Çolak, Jørgen Tobias Kühl, Anna Kalhauge, Peter Lange, Børge G Nordestgaard, Jørgen Vestbo, Susanne D Nielsen & Klaus F Kofoed
Pages: 3321-3330
Published online: 11 Oct 2018
AbstractforValidation of lung density indices by cardiac CT for quantification of lung emphysema | Full Text | References | PDF (1.3 MB)
  • 65 Views
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Article
Ectopic adiposity and cardiometabolic health in COPD
Valérie Coats, Jean-Pierre Després, Natalie Alméras, Mickaël Martin, Don D Sin, Rémi Rabasa-Lhoret, Éric Larose, Wan C Tan, Jean Bourbeau, François Maltais & On behalf of the CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network
Pages: 3331-3340
Published online: 15 Oct 2018
AbstractforEctopic adiposity and cardiometabolic health in COPD | Full Text | References | PDF (471.9 KB)
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Review

Review Article
Role of inflammatory cells in airway remodeling in COPD
Yujie Wang, Jiayan Xu, Yaqi Meng, Ian M Adcock & Xin Yao
Pages: 3341-3348
Published online: 12 Oct 2018
AbstractforRole of inflammatory cells in airway remodeling in COPD | Full Text | References | PDF (457.1 KB)
  • 723 Views
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Original Research

Article
Factors contributing to hospitalization costs for patients with COPD in China: a retrospective analysis of medical record data
Meng Li, Fengyan Wang, Rongchang Chen, Zhenyu Liang, Yumin Zhou, Yuqiong Yang, Shengqi Chen, Carolina Oi Lam Ung & Hao Hu
Pages: 3349-3357
Published online: 12 Oct 2018
AbstractforFactors contributing to hospitalization costs for patients with COPD in China: a retrospective analysis of medical record data | Full Text | References | PDF (308 KB)
  • 160 Views
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Open Access
Article
The impact of pulmonary rehabilitation on severe physical inactivity in patients with chronic obstructive pulmonary disease: a pilot study
Mimi Thyregod, Anders Løkke & Uffe Bodtger
Pages: 3359-3365
Published online: 12 Oct 2018
AbstractforThe impact of pulmonary rehabilitation on severe physical inactivity in patients with chronic obstructive pulmonary disease: a pilot study | Full Text | References | PDF (337.7 KB)
  • 109 Views
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Open Access
Article
Serum endocan levels in patients with stable COPD
Aylin Pihtili, Zuleyha Bingol & Esen Kiyan
Pages: 3367-3372
Published online: 20 Oct 2022
AbstractforSerum endocan levels in patients with stable COPD | Full Text | References | PDF (377.3 KB)
  • 101 Views
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Open Access
Article
How whole-body vibration can help our COPD patients. Physiological changes at different vibration frequencies
Eulogio Pleguezuelos, Paula Casarramona, Lluis Guirao, Beatriz Samitier, Pilar Ortega, Xavier Vila, Amin Del Carmen, Laura Ovejero, Eva Moreno, Noemi Serra, Manuel Gomís, Manuel V Garnacho-Castaño & Marc Miravitlles
Pages: 3373-3380
Published online: 18 Oct 2018
AbstractforHow whole-body vibration can help our COPD patients. Physiological changes at different vibration frequencies | Full Text | References | PDF (490.7 KB)
  • 80 Views
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Open Access
Article
Difference in systemic inflammation and predictors of acute exacerbation between smoking-associated COPD and tuberculosis-associated COPD
Jee Youn Oh, Young Seok Lee, Kyung Hoon Min, Gyu Young Hur, Sung Yong Lee, Kyung Ho Kang, Chin Kook Rhee, Seoung Ju Park & Jae Jeong Shim
Pages: 3381-3387
Published online: 18 Oct 2018
AbstractforDifference in systemic inflammation and predictors of acute exacerbation between smoking-associated COPD and tuberculosis-associated COPD | Full Text | References | PDF (779 KB)
  • 109 Views
  • 8 CrossRef citations
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Open Access
Article
Predictors of mortality in patients with COPD after 9 years
Robson Prudente, Estefânia Aparecida Thomé Franco, Carolina Bonfanti Mesquita, Renata Ferrari, Irma de Godoy & Suzana Erico Tanni
Pages: 3389-3398
Published online: 17 Oct 2018
AbstractforPredictors of mortality in patients with COPD after 9 years | Full Text | References | PDF (828.2 KB)
  • 128 Views
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Open Access
Article
Safety, tolerability, and pharmacokinetics of single and repeat ascending doses of CHF6001, a novel inhaled phosphodiesterase-4 inhibitor: two randomized trials in healthy volunteers
Fabrizia Mariotti, Mirco Govoni, Germano Lucci, Debora Santoro & Marie Anna Nandeuil
Pages: 3399-3410
Published online: 18 Oct 2018
AbstractforSafety, tolerability, and pharmacokinetics of single and repeat ascending doses of CHF6001, a novel inhaled phosphodiesterase-4 inhibitor: two randomized trials in healthy volunteers | Full Text | References | PDF (711.7 KB)
  • 77 Views
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Open Access
Article
Decreased serum club cell secretory protein in asthma and chronic obstructive pulmonary disease overlap: a pilot study
Jee Youn Oh, Young Seok Lee, Kyung Hoon Min, Gyu Young Hur, Sung Yong Lee, Kyung Ho Kang, Chin Kook Rhee, Seoung Ju Park & Jae Jeong Shim
Pages: 3411-3417
Published online: 18 Oct 2018
AbstractforDecreased serum club cell secretory protein in asthma and chronic obstructive pulmonary disease overlap: a pilot study | Full Text | References | PDF (464.8 KB)
  • 51 Views
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Editorial

Editorial
Toward effective prescription of inhaled corticosteroids in chronic airway disease
Zuzana Diamant, Guy Brusselle & Richard E Russell
Pages: 3419-3424
Published online: 18 Oct 2018
First Page PreviewforToward effective prescription of inhaled corticosteroids in chronic airway disease | Full Text | References | PDF (265.7 KB)
  • 45 Views
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Original Research

Article
Validation of the GOLD 2017 and new 16 subgroups (1A–4D) classifications in predicting exacerbation and mortality in COPD patients
Meng-Zhi Han, Tzuen-Ren Hsiue, Sheng-Han Tsai, Tang-Hsiu Huang, Xin-Min Liao & Chiung-Zuei Chen
Pages: 3425-3433
Published online: 18 Oct 2018
AbstractforValidation of the GOLD 2017 and new 16 subgroups (1A–4D) classifications in predicting exacerbation and mortality in COPD patients | Full Text | References | PDF (3.1 MB)
  • 62 Views
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Open Access
Article
Is COPD associated with periodontal disease? A population-based study in Spain
Ana Lopez-de-Andrés, Luis Vazquez-Vazquez, Maria A Martinez-Huedo, Valentín Hernández-Barrera, Isabel Jimenez-Trujillo, Miguel A Tapias-Ledesma, Javier de Miguel-Diez & Rodrigo Jiménez-García
Pages: 3435-3445
Published online: 18 Oct 2018
AbstractforIs COPD associated with periodontal disease? A population-based study in Spain | Full Text | References | PDF (376.5 KB)
  • 129 Views
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Open Access
Article
Intra- and inter-rater reproducibility of the 6-minute walk test and the 30-second sit-to-stand test in patients with severe and very severe COPD
Henrik Hansen, Nina Beyer, Anne Frølich, Nina Godtfredsen & Theresa Bieler
Pages: 3447-3457
Published online: 18 Oct 2018
AbstractforIntra- and inter-rater reproducibility of the 6-minute walk test and the 30-second sit-to-stand test in patients with severe and very severe COPD | Full Text | References | PDF (600.8 KB)
  • 440 Views
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Review

Review Article
Understanding low COPD exacerbation rates in Japan: a review and comparison with other countries
Takeo Ishii, Masaharu Nishimura, Asako Akimoto, Mark H James & Paul Jones
Pages: 3459-3471
Published online: 26 Oct 2018
AbstractforUnderstanding low COPD exacerbation rates in Japan: a review and comparison with other countries | Full Text | References | PDF (801.9 KB)
  • 104 Views
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Open Access

Original Research

Article
Clinical impacts of the classification by 2017 GOLD guideline comparing previous ones on outcomes of COPD in real-world cohorts
Jin Hwa Song, Chang-Hoon Lee, Soo-Jung Um, Yong Bum Park, Kwang Ha Yoo, Ki Suck Jung, Sang-Do Lee, Yon-Mok Oh, Ji Hyun Lee, Eun Kyung Kim, Deog Kyeom Kim & On behalf of KOLD, KOCOSS, and SNU airway registry investigators
Pages: 3473-3484
Published online: 23 Oct 2018
AbstractforClinical impacts of the classification by 2017 GOLD guideline comparing previous ones on outcomes of COPD in real-world cohorts | Full Text | References | PDF (600 KB)
  • 75 Views
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Open Access
Article
What is the impact of GOLD 2017 recommendations in primary care? – a descriptive study of patient classifications, treatment burden and costs
Alicia Gayle, Scott Dickinson, Kevin Morris, Chris Poole, Alexander G Mathioudakis & Jørgen Vestbo
Pages: 3485-3492
Published online: 23 Oct 2018
AbstractforWhat is the impact of GOLD 2017 recommendations in primary care? – a descriptive study of patient classifications, treatment burden and costs | Full Text | References | PDF (573.2 KB)
  • 88 Views
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Open Access
Article
Increased vulnerability of COPD patient groups to urban climate in view of global warming
Christina Hoffmann, Marc Hanisch, Jana B Heinsohn, Vanessa Dostal, Melissa Jehn, Uta Liebers, Wulf Pankow, Gavin C Donaldson & Christian Witt
Pages: 3493-3501
Published online: 23 Oct 2018
AbstractforIncreased vulnerability of COPD patient groups to urban climate in view of global warming | Full Text | References | PDF (1.7 MB)
  • 170 Views
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Article
Inhaled corticosteroids might not increase the risk of pneumonia in patients with chronic obstructive pulmonary disease in Japan
Ryosuke Hirano, Masaki Fujita, Takemasa Matsumoto, Rintaro On & Kentaro Watanabe
Pages: 3503-3509
Published online: 23 Oct 2018
AbstractforInhaled corticosteroids might not increase the risk of pneumonia in patients with chronic obstructive pulmonary disease in Japan | Full Text | References | PDF (344.3 KB)
  • 69 Views
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Editorial

Editorial
Bronchodilator responsiveness or reversibility in asthma and COPD – a need for clarity
Igor Barjaktarevic, Robert Kaner, Russell G Buhr & Christopher B Cooper
Pages: 3511-3513
Published online: 23 Oct 2018
First Page PreviewforBronchodilator responsiveness or reversibility in asthma and COPD – a need for clarity | Full Text | References | PDF (204.1 KB)
  • 103 Views
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Original Research

Article
The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance
Christian R Osadnik, Matthias Loeckx, Zafeiris Louvaris, Heleen Demeyer, Daniel Langer, Fernanda M Rodrigues, Wim Janssens, Ioannis Vogiatzis & Thierry Troosters
Pages: 3515-3527
Published online: 24 Oct 2018
AbstractforThe likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance | Full Text | References | PDF (2.3 MB)
  • 177 Views
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Open Access
Article
Exercise performance and symptoms in lowlanders with COPD ascending to moderate altitude: randomized trial
Michael Furian, Deborah Flueck, Tsogyal D Latshang, Philipp M Scheiwiller, Sebastian Daniel Segitz, Séverine Mueller-Mottet, Christian Murer, Adrian Steiner, Silvia Ulrich, Thomas Rothe, Malcolm Kohler & Konrad E Bloch
Pages: 3529-3538
Published online: 26 Oct 2018
AbstractforExercise performance and symptoms in lowlanders with COPD ascending to moderate altitude: randomized trial | Full Text | References | PDF (502.1 KB)
  • 140 Views
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Review

Review Article
The dose of inhaled corticosteroids in patients with COPD: when less is better
José Luis Izquierdo & Borja G Cosio
Pages: 3539-3547
Published online: 25 Oct 2018
AbstractforThe dose of inhaled corticosteroids in patients with COPD: when less is better | Full Text | References | PDF (593.2 KB)
  • 163 Views
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Original Research

Article
Outcomes for symptomatic non-obstructed individuals and individuals with mild (GOLD stage 1) COPD in a population based cohort
Rogelio Perez-Padilla, Fernando C Wehrmeister, Maria Montes de Oca, Maria Victorina Lopez, Jose R Jardim, Adriana Muiño, Gonzalo Valdivia, Ana Maria B Menezes & On behalf of the PLATINO group
Pages: 3549-3561
Published online: 26 Oct 2018
AbstractforOutcomes for symptomatic non-obstructed individuals and individuals with mild (GOLD stage 1) COPD in a population based cohort | Full Text | References | PDF (637.6 KB)
  • 69 Views
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Open Access

Original Researc

Article
Influence of the type of emphysema in the relationship between COPD and lung cancer
Cecilia Mouronte-Roibás, Alberto Fernández-Villar, Alberto Ruano-Raviña, Cristina Ramos-Hernández, Amara Tilve-Gómez, Paula Rodríguez-Fernández, Adriana Carolina Caldera Díaz, Míriam García Vázquez-Noguerol, Sara Fernández-García & Virginia Leiro-Fernández
Pages: 3563-3570
Published online: 29 Oct 2018
AbstractforInfluence of the type of emphysema in the relationship between COPD and lung cancer | Full Text | References | PDF (445.9 KB)
  • 235 Views
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Open Access

Review

Review Article
Interventions to increase referral and uptake to pulmonary rehabilitation in people with COPD: a systematic review
Frances Early, Ian Wellwood, Isla Kuhn, Christi Deaton & Jonathan Fuld
Pages: 3571-3586
Published online: 29 Oct 2018
AbstractforInterventions to increase referral and uptake to pulmonary rehabilitation in people with COPD: a systematic review | Full Text | References | PDF (452.3 KB)
  • 410 Views
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Open Access

Corrigendum

Correction
Tiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study [Corrigendum]
Page: 3587
Published online: 30 Oct 2018
CitationforTiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study [Corrigendum] | Full Text | PDF (282.1 KB)
  • 38 Views
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Original Research

Article
Blood eosinophil count as a prognostic biomarker in COPD
Yeon-Mok Oh, Keu Sung Lee, Yoonki Hong, Sung Chul Hwang, Jae Yeol Kim, Deog Keom Kim, Kwang Ha Yoo, Ji-Hyun Lee, Tae-Hyung Kim, Seong Yong Lim, Chin Kook Rhee, Hyoung Kyu Yoon, Sang Yeub Lee, Yong Bum Park, Jin Hee Jung, Woo Jin Kim, Sang-Do Lee & Joo Hun Park
Pages: 3589-3596
Published online: 31 Oct 2018
AbstractforBlood eosinophil count as a prognostic biomarker in COPD | Full Text | References | PDF (603.8 KB)
  • 172 Views
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Open Access

Corrigendum

Correction
The impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: a quantitative synthesis [Corrigendum]
Page: 3597
Published online: 31 Oct 2018
CitationforThe impact of dual bronchodilation on cardiovascular serious adverse events and mortality in COPD: a quantitative synthesis [Corrigendum] | Full Text | PDF (140.2 KB)
  • 38 Views
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Open Access

Original Research

Article
Exercise capacity in COPD patients with exercise-induced pulmonary hypertension
Ingunn Skjørten, Janne Mykland Hilde, Morten Nissen Melsom, Jonny Hisdal, Viggo Hansteen, Kjetil Steine & Sjur Humerfelt
Pages: 3599-3610
Published online: 31 Oct 2018
AbstractforExercise capacity in COPD patients with exercise-induced pulmonary hypertension | Full Text | References | PDF (5.9 MB)
  • 82 Views
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Open Access
Article
Cholinergic mechanisms in an organic dust model simulating an acute exacerbation in patients with COPD
Lena Palmberg, Britt-Marie Sundblad, Jie Ji, Jakob Karén & Kjell Larsson
Pages: 3611-3624
Published online: 01 Nov 2018
AbstractforCholinergic mechanisms in an organic dust model simulating an acute exacerbation in patients with COPD | Full Text | References | PDF (1.1 MB)
  • 54 Views
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Open Access
Article
Improvement in hypercapnia does not predict survival in COPD patients on chronic noninvasive ventilation
Tim Raveling, Gerrie Bladder, Judith M Vonk, Jellie A Nieuwenhuis, Fransien M Verdonk-Struik, Peter J Wijkstra & Marieke L Duiverman
Pages: 3625-3634
Published online: 01 Nov 2018
AbstractforImprovement in hypercapnia does not predict survival in COPD patients on chronic noninvasive ventilation | Full Text | References | PDF (477.9 KB)
  • 93 Views
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Open Access
Article
Nasal high flow, but not supplemental O2, reduces peripheral vascular sympathetic activity during sleep in COPD patients
K Fricke, H Schneider, P Biselli, NN Hansel, ZG Zhang, MO Sowho & L Grote
Pages: 3635-3643
Published online: 02 Nov 2018
AbstractforNasal high flow, but not supplemental O2, reduces peripheral vascular sympathetic activity during sleep in COPD patients | Full Text | References | PDF (935.6 KB)
  • 66 Views
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Open Access

Case Series

Endobronchial coil treatment in severe emphysema patients with alpha-1 antitrypsin deficiency
Jeanne Marie Perotin, Sylvie Leroy, Charles Hugo Marquette, Hervé Mal, Hervé Dutau, Arnaud Bourdin, Jean Michel Vergnon, Christophe Pison, Coralie Barbe, Gaëtan Deslee & On behalf of the REVOLENS Study Group
Pages: 3645-3649
Published online: 05 Nov 2018
AbstractforEndobronchial coil treatment in severe emphysema patients with alpha-1 antitrypsin deficiency | Full Text | References | PDF (244.5 KB)
  • 69 Views
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Open Access

Review

Review Article
Defining the role of neutrophil-to-lymphocyte ratio in COPD: a systematic literature review
Yuliana Pascual-González, Marta López-Sánchez, Jordi Dorca & Salud Santos
Pages: 3651-3662
Published online: 05 Nov 2018
AbstractforDefining the role of neutrophil-to-lymphocyte ratio in COPD: a systematic literature review | Full Text | References | PDF (569.8 KB)
  • 340 Views
  • 27 CrossRef citations
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Open Access

Short Report

Brief Report
Sputum Moraxella catarrhalis strains exhibit diversity within and between COPD subjects
Leena M George, Richard D Haigh, Vijay Mistry, Koirobi Haldar, Michael R Barer, Marco R Oggioni & Christopher E Brightling
Pages: 3663-3667
Published online: 08 Nov 2018
AbstractforSputum Moraxella catarrhalis strains exhibit diversity within and between COPD subjects | Full Text | References | PDF (653 KB)
  • 54 Views
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Open Access

Original Research

Article
Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids
Salman H Siddiqui, Ian D Pavord, Neil C Barnes, Alessandro Guasconi, Sally Lettis, Steven Pascoe & Stefano Petruzzelli
Pages: 3669-3676
Published online: 06 Nov 2018
AbstractforBlood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids | Full Text | References | PDF (2.6 MB)
  • 99 Views
  • 24 CrossRef citations
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Open Access
Article
Effects of a COPD self-management support intervention: a randomized controlled trial
Heidi B Bringsvor, Eva Langeland, Bjørg Frøysland Oftedal, Knut Skaug, Jörg Assmus & Signe Berit Bentsen
Pages: 3677-3688
Published online: 20 Oct 2022
AbstractforEffects of a COPD self-management support intervention: a randomized controlled trial | Full Text | References | PDF (434.5 KB)
  • 454 Views
  • 16 CrossRef citations
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Open Access
Article
Lung function and CT lung densitometry in 37- to 39-year-old individuals with alpha-1-antitrypsin deficiency
Behrouz Mostafavi, Sandra Diaz, Eeva Piitulainen, Berend C Stoel, Per Wollmer & Hanan A Tanash
Pages: 3689-3698
Published online: 08 Nov 2018
AbstractforLung function and CT lung densitometry in 37- to 39-year-old individuals with alpha-1-antitrypsin deficiency | Full Text | References | PDF (772 KB)
  • 66 Views
  • 13 CrossRef citations
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Open Access
Article
The association of elevated circulating endocan levels with lung function decline in COPD patients
Luqi Dai, Junyun He, Jun Chen, Tao Wang, Lian Liu, Yongchun Shen, Lei Chen & Fuqiang Wen
Pages: 3699-3706
Published online: 09 Nov 2018
AbstractforThe association of elevated circulating endocan levels with lung function decline in COPD patients | Full Text | References | PDF (670.1 KB)
  • 94 Views
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Open Access
Article
Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study
Adam J Białas, Karolina Siewiera, Cezary Watała, Anna Rybicka, Bartłomiej Grobelski, Leon Kośmider, Jolanta Kurek, Joanna Miłkowska-Dymanowska, Wojciech J Piotrowski & Paweł Górski
Pages: 3707-3717
Published online: 20 Oct 2022
AbstractforMitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study | Full Text | References | PDF (2.2 MB)
  • 53 Views
  • 3 CrossRef citations
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Open Access
Article
Validation of clinical control in COPD as a new tool for optimizing treatment
Juan José Soler-Cataluña, Maribel Marzo, Pablo Catalán, Cristina Miralles, Bernardino Alcazar & Marc Miravitlles
Pages: 3719-3731
Published online: 14 Nov 2018
AbstractforValidation of clinical control in COPD as a new tool for optimizing treatment | Full Text | References | PDF (737.1 KB)
  • 113 Views
  • 33 CrossRef citations
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Open Access
Article
Identification of novel candidate genes involved in the progression of emphysema by bioinformatic methods
Wei-Ping Hu, Ying-Ying Zeng, Yi-Hui Zuo & Jing Zhang
Pages: 3733-3747
Published online: 20 Oct 2022
AbstractforIdentification of novel candidate genes involved in the progression of emphysema by bioinformatic methods | Full Text | References | PDF (4.8 MB)
  • 125 Views
  • 9 CrossRef citations
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Open Access
Article
Role of microparticles derived from monocytes, endothelial cells and platelets in the exacerbation of COPD
Margit Tőkés-Füzesi, István Ruzsics, Orsolya Rideg, Péter Kustán, Gábor L Kovács & Tihamér Molnár
Pages: 3749-3757
Published online: 20 Oct 2022
AbstractforRole of microparticles derived from monocytes, endothelial cells and platelets in the exacerbation of COPD | Full Text | References | PDF (1.3 MB)
  • 74 Views
  • 10 CrossRef citations
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Open Access
Article
Enhancing our understanding of the time course of acute exacerbations of COPD managed on an outpatient basis
Ana Oliveira, Vera Afreixo & Alda Marques
Pages: 3759-3766
Published online: 20 Nov 2018
AbstractforEnhancing our understanding of the time course of acute exacerbations of COPD managed on an outpatient basis | Full Text | References | PDF (505.3 KB)
  • 58 Views
  • 4 CrossRef citations
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Open Access
Article
Impact of COPD on prognosis of lung cancer: from a perspective on disease heterogeneity
Wei Wang, Shuang Dou, Wenyan Dong, Mengshuang Xie, Liwei Cui, Chunyan Zheng & Wei Xiao
Pages: 3767-3776
Published online: 20 Nov 2018
AbstractforImpact of COPD on prognosis of lung cancer: from a perspective on disease heterogeneity | Full Text | References | PDF (1.2 MB)
  • 158 Views
  • 19 CrossRef citations
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Open Access
Article
miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension
Jing Jiang, Yimeng Xia, Yi Liang, Meiling Yang, Wen Zeng & Xiaocong Zeng
Pages: 3777-3790
Published online: 20 Nov 2018
AbstractformiR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension | Full Text | References | PDF (3.7 MB)
  • 72 Views
  • 18 CrossRef citations
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Open Access
Article
Correlation of serum levels of HIF-1α and IL-19 with the disease progression of COPD: a retrospective study
Biaoxue Rong, Yufang Liu, Min Li, Tian Fu, Wenlong Gao & Hua Liu
Pages: 3791-3803
Published online: 21 Nov 2018
AbstractforCorrelation of serum levels of HIF-1α and IL-19 with the disease progression of COPD: a retrospective study | Full Text | References | PDF (13.3 MB)
  • 62 Views
  • 18 CrossRef citations
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Open Access
Article
Impact of chemotherapy in the prognosis of non-small-cell lung cancer patients with severe to very severe COPD
Weigang Dong, Yan Du & Shuping Ma
Pages: 3805-3812
Published online: 21 Nov 2018
AbstractforImpact of chemotherapy in the prognosis of non-small-cell lung cancer patients with severe to very severe COPD | Full Text | References | PDF (485.9 KB)
  • 55 Views
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Open Access

Review

Review Article
Long-term macrolide treatment for the prevention of acute exacerbations in COPD: a systematic review and meta-analysis
Yanan Cui, Lijuan Luo, Chenbei Li, Ping Chen & Yan Chen
Pages: 3813-3829
Published online: 22 Nov 2018
AbstractforLong-term macrolide treatment for the prevention of acute exacerbations in COPD: a systematic review and meta-analysis | Full Text | References | PDF (1.4 MB)
  • 212 Views
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Open Access

Original Research

Article
Digitalizing multidisciplinary pulmonary rehabilitation in COPD with a smartphone application: an international observational pilot study
Frank Rassouli, David Boutellier, Jonas Duss, Stephan Huber & Martin H Brutsche
Pages: 3831-3836
Published online: 23 Nov 2018
AbstractforDigitalizing multidisciplinary pulmonary rehabilitation in COPD with a smartphone application: an international observational pilot study | Full Text | References | PDF (876.6 KB)
  • 239 Views
  • 30 CrossRef citations
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Open Access
Article
Evaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire
Alexa Núñez, Cristina Esquinas, Miriam Barrecheguren, Myriam Calle, Ricard Casamor & Marc Miravitlles
Pages: 3837-3844
Published online: 26 Nov 2018
AbstractforEvaluating the impact of morning symptoms in COPD using the Capacity of Daily Living during the Morning (CDLM) questionnaire | Full Text | References | PDF (754.1 KB)
  • 63 Views
  • 3 CrossRef citations
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Open Access
Article
Continuous quantitative measurement of the main bronchial dimensions and lung density in the lateral position by four-dimensional dynamic-ventilation CT in smokers and COPD patients
Yukihiro Nagatani, Masayuki Hashimoto, Norihisa Nitta, Yasuhiko Oshio, Tsuneo Yamashiro, Shigetaka Sato, Shinsuke Tsukagoshi, Hiroshi Moriya, Tatsuya Kimoto, Tomoyuki Igarashi, Noritoshi Ushio, Akinaga Sonoda, Hideji Otani, Jun Hanaoka, Kiyoshi Murata & On behalf of investigators of the ACTIve Study Group
Pages: 3845-3856
Published online: 27 Nov 2018
AbstractforContinuous quantitative measurement of the main bronchial dimensions and lung density in the lateral position by four-dimensional dynamic-ventilation CT in smokers and COPD patients | Full Text | References | PDF (1.3 MB)
  • 57 Views
  • 1 CrossRef citations
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Open Access
Article
Influence of comorbid heart disease on dyspnea and health status in patients with COPD – a cohort study
Maaike Giezeman, Mikael Hasselgren, Karin Lisspers, Björn Ställberg, Scott Montgomery, Christer Janson & Josefin Sundh
Pages: 3857-3865
Published online: 28 Nov 2018
AbstractforInfluence of comorbid heart disease on dyspnea and health status in patients with COPD – a cohort study | Full Text | References | PDF (592 KB)
  • 57 Views
  • 9 CrossRef citations
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Open Access
Article
Cost-effectiveness of twice-daily indacaterol/glycopyrrolate inhalation powder for the treatment of moderate to severe COPD in the US
Krithika Rajagopalan, Lisa Bloudek, Jessica Marvel, Carole Dembek & Abhishek Kavati
Pages: 3867-3877
Published online: 28 Nov 2018
AbstractforCost-effectiveness of twice-daily indacaterol/glycopyrrolate inhalation powder for the treatment of moderate to severe COPD in the US | Full Text | References | PDF (629.8 KB)
  • 77 Views
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Open Access

Short Report

Brief Report
The usefulness of soluble receptor for advanced glycation end-products in the identification of COPD frequent exacerbator phenotype
Joanna Miłkowska-Dymanowska, Adam J Białas, Karolina Szewczyk, Zofia Kurmanowska, Paweł Górski & Wojciech J Piotrowski
Pages: 3879-3884
Published online: 29 Nov 2018
AbstractforThe usefulness of soluble receptor for advanced glycation end-products in the identification of COPD frequent exacerbator phenotype | Full Text | References | PDF (363 KB)
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Original Research

Article
The Manchester Respiratory-related Sleep Symptoms scale for patients with COPD: development and validation
Naimat Khan, Jørgen Vestbo, Adam Garrow, Pradeep Karur, Umme Kolsum, Sarah Tyson, Dave Singh & Janelle Yorke
Pages: 3885-3894
Published online: 29 Nov 2018
AbstractforThe Manchester Respiratory-related Sleep Symptoms scale for patients with COPD: development and validation | Full Text | References | PDF (490.3 KB)
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Open Access

Research Letter

Article
Nasal high-flow in acute hypercapnic exacerbation of COPD
Jens Bräunlich & Hubert Wirtz
Pages: 3895-3897
Published online: 30 Nov 2018
First Page PreviewforNasal high-flow in acute hypercapnic exacerbation of COPD | Full Text | References | PDF (429.6 KB)
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Open Access

Erratum

Correction
What is the impact of GOLD 2017 recommendations in primary care? – a descriptive study of patient classifications, treatment burden and costs [Erratum]
Page: 3899
Published online: 05 Dec 2018
CitationforWhat is the impact of GOLD 2017 recommendations in primary care? – a descriptive study of patient classifications, treatment burden and costs [Erratum] | Full Text | PDF (158 KB)
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Original Research

Article
Characteristics of 2017 GOLD COPD group A: a multicenter cross-sectional CAP study in Japan
Keiji Oishi, Tsunahiko Hirano, Kazuki Hamada, Sho Uehara, Ryo Suetake, Yoshikazu Yamaji, Kosuke Ito, Maki Asami-Noyama, Nobutaka Edakuni & Kazuto Matsunaga
Pages: 3901-3907
Published online: 05 Dec 2018
AbstractforCharacteristics of 2017 GOLD COPD group A: a multicenter cross-sectional CAP study in Japan | Full Text | References | PDF (1.2 MB)
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Open Access
Article
Preliminary study: comparative effects of lung volume therapy between slow and fast deep-breathing techniques on pulmonary function, respiratory muscle strength, oxidative stress, cytokines, 6-minute walking distance, and quality of life in persons with COPD
Jirakrit Leelarungrayub, Rungthip Puntumetakul, Thanyaluck Sriboonreung, Yothin Pothasak & Jakkrit Klaphajone
Pages: 3909-3921
Published online: 05 Dec 2018
AbstractforPreliminary study: comparative effects of lung volume therapy between slow and fast deep-breathing techniques on pulmonary function, respiratory muscle strength, oxidative stress, cytokines, 6-minute walking distance, and quality of life in persons with COPD | Full Text | References | PDF (656.4 KB)
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Article
Indacaterol acetate/mometasone furoate provides sustained improvements in lung function compared with salmeterol xinafoate/fluticasone propionate in patients with moderate-to-very-severe COPD: results from a Phase II randomized, double-blind 12-week study
Kai Michael Beeh, Anne-Marie Kirsten, Ana-Maria Tanase, Alexia Richard, Weihua Cao, Bettina Hederer, Jutta Beier, Oliver Kornmann & Richard N van Zyl-Smit
Pages: 3923-3936
Published online: 06 Dec 2018
AbstractforIndacaterol acetate/mometasone furoate provides sustained improvements in lung function compared with salmeterol xinafoate/fluticasone propionate in patients with moderate-to-very-severe COPD: results from a Phase II randomized, double-blind 12-week study | Full Text | References | PDF (765.1 KB)
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Article
Physiological predictors Of peak inspiRatory flow using Observed lung function resultS (POROS): evaluation at discharge among patients hospitalized for a COPD exacerbation
David B Price, Sen Yang, Simon Wan Yau Ming, Antony Hardjojo, Claudia Cabrera, Andriana I Papaioannou, Stelios Loukides, Vicky Kritikos, Sinthia Z Bosnic-Anticevich, Victoria Carter & Paul M Dorinsky
Pages: 3937-3946
Published online: 13 Dec 2018
AbstractforPhysiological predictors Of peak inspiRatory flow using Observed lung function resultS (POROS): evaluation at discharge among patients hospitalized for a COPD exacerbation | Full Text | References | PDF (300.2 KB)
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Article
Clinical characteristics and outcomes in Japanese patients with COPD according to the 2017 GOLD classification: the Ishinomaki COPD Network Registry
Seiichi Kobayashi, Masakazu Hanagama, Masatsugu Ishida, Hikari Sato, Manabu Ono, Shinsuke Yamanda, Mitsuhiro Yamada, Hiroyuki Aizawa & Masaru Yanai
Pages: 3947-3955
Published online: 06 Dec 2018
AbstractforClinical characteristics and outcomes in Japanese patients with COPD according to the 2017 GOLD classification: the Ishinomaki COPD Network Registry | Full Text | References | PDF (402.4 KB)
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Article
New evaluation of trunk movement and balance during walking in COPD patients by a triaxial accelerometer
Yoshino Terui, Masahiro Iwakura, Eriko Suto, Atsuyoshi Kawagoshi, Keiyu Sugawara, Hitomi Takahashi, Kouichi Hasegawa, Sachiko Uemura, Masahiro Satake & Takanobu Shioya
Pages: 3957-3962
Published online: 07 Dec 2018
AbstractforNew evaluation of trunk movement and balance during walking in COPD patients by a triaxial accelerometer | Full Text | References | PDF (761.3 KB)
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Article
Reassessing the BODE score as a criterion for listing COPD patients for lung transplantation
Lionel Pirard & Eric Marchand
Pages: 3963-3970
Published online: 20 Oct 2022
AbstractforReassessing the BODE score as a criterion for listing COPD patients for lung transplantation | Full Text | References | PDF (529.2 KB)
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Review

Review Article
Triple therapy (ICS/LABA/LAMA) in COPD: time for a reappraisal
Lowie Vanfleteren, Leonardo M Fabbri, Alberto Papi, Stefano Petruzzelli & Bartolome Celli
Pages: 3971-3981
Published online: 12 Dec 2018
AbstractforTriple therapy (ICS/LABA/LAMA) in COPD: time for a reappraisal | Full Text | References | PDF (936.3 KB)
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Original Research

Article
Heterogeneity in the respiratory symptoms of patients with mild-to-moderate COPD
Kate M Johnson, Abdollah Safari, Wan C Tan, Jean Bourbeau, J Mark FitzGerald, Mohsen Sadatsafavi, On behalf of the Canadian Cohort of Obstructive Lung Disease (CanCOLD) study & the Canadian Respiratory Research Network
Pages: 3983-3995
Published online: 13 Dec 2018
AbstractforHeterogeneity in the respiratory symptoms of patients with mild-to-moderate COPD | Full Text | References | PDF (1.1 MB)
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Article
Automated oxygen control with O2matic® during admission with exacerbation of COPD
Ejvind Frausing Hansen, Jens Dahlgaard Hove, Charlotte Sandau Bech, Jens-Ulrik Stæhr Jensen, Thomas Kallemose & Jørgen Vestbo
Pages: 3997-4003
Published online: 14 Dec 2018
AbstractforAutomated oxygen control with O2matic® during admission with exacerbation of COPD | Full Text | References | PDF (1.7 MB)
  • 149 Views
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Article
Post-discharge extended care contributes to the disease control of patients with COPD: a Chinese study
Min Li, Rong Hu, Xiaoyang Liu, Shuping Tao & Biaoxue Rong
Pages: 4005-4013
Published online: 14 Dec 2018
AbstractforPost-discharge extended care contributes to the disease control of patients with COPD: a Chinese study | Full Text | References | PDF (1.5 MB)
  • 44 Views
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