Evaluation of Biogenic Silver Nanoparticles Synthesized from Vegetable Waste

Abstract

Introduction

Vegetable waste has numerous essential values and can be used for various purposes. Unfortunately, it is often discarded worldwide due to a lack of awareness regarding its nutritional and practical significance. Even the nutrient-rich peels of fruits and vegetables are commonly wasted, despite their numerous useful applications. Utilizing vegetable waste to produce silver nanoparticles through green synthesis is an advantageous, economical, and environmentally friendly method for producing valuable products while addressing waste management concerns. The main emphasis of this study was to synthesize silver nanoparticles (AgNPs) by using vegetable waste from Solanum tuberosum (potato) and Coriander sativum (coriander).

Methods

The stems of Coriander sativum and peels of Solanum tuberosum were used as extracts for the synthesis of AgNPs. The characterization of the synthesized AgNPs involved UV-spectroscopy, scanning electron microscopy (SEM), and X-ray diffraction (XRD). The phytochemical analysis was performed to analyze antimicrobial, cytotoxic, antidiabetic, antitumor, antioxidant, alpha-amylase, and protein inhibition activities.

Results

The change in the color of the reaction mixture from yellowish green to brown following the addition of extracts to the silver nitrate solution confirmed nanoparticle synthesis. UV analysis has shown peaks in the range of 300–400nm. SEM confirmed the spherical and agglomerated morphology and size of 64nm for potato peel and 70nm for coriander stem. XRD confirmed the crystalline structure of silver nanoparticles. The phytochemical assays confirmed that silver nanoparticles had higher total phenolic and flavonoid contents. The biosynthesized silver nanoparticles showed promising antimicrobial, cytotoxic, antidiabetic, antitumor, and antioxidant properties and significant alpha-amylase and protein inhibition activities in comparison with the crude extracts.

Conclusion

The bioactivity of the plant suggests that it could be a suitable option for therapeutic purposes. This study demonstrates a potential method for sustainable nanoparticle synthesis and the therapeutic applications of AgNPs derived from vegetable waste. By utilizing the potential of vegetable waste, we can contribute to both environmental sustainability and the development of innovative, valuable products in fields such as medicine, agriculture, and materials science. These findings encourage further research on agricultural byproducts, promoting environmentally friendly and economically advantageous research and development efforts.

Graphical Abstract

Keywords:

• silver nanoparticles
• vegetable waste
• antimicrobial
• antidiabetic
• Coriander sativum
• Solanum tuberosum

Ethics Approval

The present study followed national guidelines of Pakistan National Bioethics Committee for Research for animal treatment. The Pakistan National Bioethics committee and Institutional Review Board and Ethics Committee of International Islamic University, Islamabad reviewed and approved this study under relevant legislation from Pakistan’s Prevention of Cruelty to Animals Act 1890.

No additional approvals were required to conduct research with plant material, in accordance with institutional/local regulations.

Acknowledgment

The authors extend their appreciation to the Researchers Supporting Project number (RSPD2023R725) King Saud University, Riyadh, Saudi Arabia.

Author Contributions

All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.

Disclosure

The authors report no conflicts of interest in this work.

Additional information

Funding

The funding for this project was provided by the Researchers Supporting Project number (RSPD2023R725) King Saud University, Riyadh, Saudi Arabia.