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Original Research

RETRACTED ARTICLE: Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling

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Pages 6619-6632 | Published online: 07 Dec 2021
 

Abstract

Yao Y, Li C, Qian F, et al. J Inflamm Res. 2021;14:6619–6632.

The Editor and Publisher of the Journal of Inflammation Research are retracting the published article. The authors requested to correct errors with images from Figure 3, however it was found that some of the images had been duplicated with those from Yao YY, Li R, Guo YJ, et al. Gastrodin Attenuates Lipopolysaccharide-Induced Inflammatory Response and Migration via the Notch-1 Signaling Pathway in Activated Microglia. Neuromol Med. 2022;24:139–154. https://doi.org/10.1007/s12017-021-08671-1. Specifically,

  • The images for Figure 3C, Control; p-STAT3; Lectin; Merge and LPS+Rg1(60µM); p-STAT3; Lectin; Merge have been duplicated with the images for Figure 3C, Control; NICD, Lectin; Merge and LPS; NICD, Lectin, Merge, respectively, from Yao YY et al (2022).

The authors cooperated with our queries and explained the errors were made during the assembly of the figures and discovered following an internal academic review. The authors also provided the journal with original data from their study. However, the errors did raise concerns over the reliability and validity of the findings and the Editor and Publisher made the decision to retract the article and the authors do not agree with this decision.

We have been informed in our decision-making by our editorial policies and the COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

View retraction statement:
Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling [Retraction]

Additional information

Funding

This study was supported by the National Natural Sciences Foundation of China (Grants No. 81960251, 81460210, 81360200), Department project of Science and Technology of Yunnan Province (Grants No. 2018FE001(-029), 202001AY070001-174) and the Department project of Education of Yunnan Province (Grant No. 2019J1214).