Remediable shortcomings in applying clinical pharmacology to neurological practice

Abstract

The application of the clinical pharmacological approach to prescribing antiepileptic drugs has enhanced the efficiency of the drug treatment of epilepsy considerably. However, it would be possible to take the approach further in relation to this disorder by applying it to the more recently introduced antiepileptic drugs, to specific epileptic seizure syndromes and to seizure disorders of different degrees of activity. Similarly, the approach could be applied to the drug treatment of migraine attacks, to migraine prophylactic therapy and to the treatments of multiple sclerosis and Parkinsonism, with reasonable expectations that it would enhance the therapy of these disorders.

Keywords: :

• drug concentration
• epilepsy
• migraine
• multiple sclerosis
• parkinsonism
• pharmacokinetics
• therapeutic range