Familial Essential Thrombocyteemia

E. Fernandez-Robles Department of Haematology, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, avenue Hippocrate 10, 1200, Brussels, Belgium

C. Vermylen Department of Haematology, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, avenue Hippocrate 10, 1200, Brussels, Belgium

P. Martiat Department of Haematology, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, avenue Hippocrate 10, 1200, Brussels, Belgium

J. Ninane Department of Haematology, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, avenue Hippocrate 10, 1200, Brussels, Belgium

G. Cornu Department of Haematology, Cliniques Universitaires Saint-Luc, Catholic University of Louvain, avenue Hippocrate 10, 1200, Brussels, Belgium

Abstract

We report three siblings (2 F, 1 M) aged 9, 12, and 15 years with a thrombocytosis, above 650 × 10⁹/l for at least 18 months and a leukocyte alkaline phosphatase score below 37. The diagnosis of essential thrombocythemia was based upon the exclusion of a reactive thrombocytosis or another myeloproliferative disease. Cytogenetic examination of marrow cells was normal.

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Familial Essential Thrombocyteemia

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Familial Essential Thrombocyteemia

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