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Review Article

Lipid-based nanocarriers for breast cancer treatment – comprehensive review

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Pages 1291-1305 | Received 17 Jul 2015, Accepted 06 Sep 2015, Published online: 02 Oct 2015
 

Abstract

Breast cancer is the second leading cancer-related disease as the most common non-cutaneous malignancy among women. Curative options for breast cancer are limited, therapeutically substantial and associated with toxicities. Emerging nanotechnologies exhibited the possibility to treat or target breast cancer. Among the nanoparticles, various lipid nanoparticles namely, liposomes, solid lipid nanoparticles, nanostructured lipid carriers and lipid polymer hybrid nanoparticles have been developed over the years for the breast cancer therapy and evidences are documented. Concepts are confined in lab scale, which needs to be transferred to large scale to develop active targeting nanomedicine for the clinical utility. So, the present review highlights the recently published studies in the development of lipid-based nanocarriers for breast cancer treatment.

Acknowldgements

The authors are thankful to Shashank Tummala, Shashank Mulukutla, Research scholars, JSS College of Pharmacy, Udhagamandalam for giving valuable time and suggestions in preparation of this manuscript.

Declaration of interest

All the authors have no competing interests.

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