Drug Delivery, Volume 23, Issue 4 (2016)

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Drug Delivery, Volume 23, Issue 4 (2016)

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Liposome- and lipid-based drug delivery

Review Article

Review
Liposomes in topical ophthalmic drug delivery: an update
Renu Agarwal, Igor Iezhitsa, Puneet Agarwal, Nurul Alimah Abdul Nasir, Norhafiza Razali, Renad Alyautdin & Nafeeza Mohd Ismail
Pages: 1075-1091
Published online: 12 Aug 2014
AbstractforLiposomes in topical ophthalmic drug delivery: an update | Full Text | References | PDF (1.4 MB)
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Critical Review

Review
Are PEGylated liposomes better than conventional liposomes? A special case for vincristine
Xuling Wang, Yanzhi Song, Yuqing Su, Qingjing Tian, Boqun Li, Jingjing Quan & Yihui Deng
Pages: 1092-1100
Published online: 29 May 2015
AbstractforAre PEGylated liposomes better than conventional liposomes? A special case for vincristine | Full Text | References | PDF (444.8 KB)
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Research Article

Article
EpCAM-targeted liposomal si-RNA delivery for treatment of epithelial cancer
Dhiraj Bhavsar, Krishnakumar Subramanian, Swaminathan Sethuraman & Uma Maheswari Krishnan
Pages: 1101-1114
Published online: 24 Nov 2014
AbstractforEpCAM-targeted liposomal si-RNA delivery for treatment of epithelial cancer | Full Text | References | PDF (2.4 MB)
  • 1919 Views
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Article
Elastic liposome-based gel for topical delivery of 5-fluorouracil: in vitro and in vivo investigation
Afzal Hussain, Abdus Samad, Mohammad Ramzan, Mohd Neyaz Ahsan, Zia Ur Rehman & Farhan Jalees Ahmad
Pages: 1115-1129
Published online: 07 Nov 2014
AbstractforElastic liposome-based gel for topical delivery of 5-fluorouracil: in vitro and in vivo investigation | Full Text | References | PDF (2.8 MB)
  • 3412 Views
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Article
Co-delivery of doxorubicin and P-gp inhibitor by a reduction-sensitive liposome to overcome multidrug resistance, enhance anti-tumor efficiency and reduce toxicity
Jie Tang, Li Zhang, Huile Gao, Yayuan Liu, Qianyu Zhang, Rui Ran, Zhirong Zhang & Qin He
Pages: 1130-1143
Published online: 10 Dec 2014
AbstractforCo-delivery of doxorubicin and P-gp inhibitor by a reduction-sensitive liposome to overcome multidrug resistance, enhance anti-tumor efficiency and reduce toxicity | Full Text | References | PDF (3.6 MB) | Supplemental
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Article
Preparation and ocular pharmacokinetics of hyaluronan acid-modified mucoadhesive liposomes
Jing Lin, Hongjie Wu, Yingjun Wang, Jianhong Lin, Qing Chen & Xuan Zhu
Pages: 1144-1151
Published online: 23 Dec 2014
AbstractforPreparation and ocular pharmacokinetics of hyaluronan acid-modified mucoadhesive liposomes | Full Text | References | PDF (1.5 MB)
  • 1748 Views
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Article
Surface-modified Epirubicin-HCl liposomes and its in vitro assessment in breast cancer cell-line: MCF-7
Ravi Gandhi, Nirav Khatri, Dipesh Baradia, Imran Vhora & Ambikanandan Misra
Pages: 1152-1162
Published online: 14 Jan 2015
AbstractforSurface-modified Epirubicin-HCl liposomes and its in vitro assessment in breast cancer cell-line: MCF-7 | Full Text | References | PDF (1.5 MB)
  • 1818 Views
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Article
Development of an anti-microbial peptide-mediated liposomal delivery system: a novel approach towards pH-responsive anti-microbial peptides
Qianyu Zhang, Jie Tang, Rui Ran, Yayuan Liu, Zhirong Zhang, Huile Gao & Qin He
Pages: 1163-1170
Published online: 19 Feb 2015
AbstractforDevelopment of an anti-microbial peptide-mediated liposomal delivery system: a novel approach towards pH-responsive anti-microbial peptides | Full Text | References | PDF (1.4 MB) | Supplemental
  • 1410 Views
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Article
Targeted delivery of transferrin and TAT co-modified liposomes encapsulating both paclitaxel and doxorubicin for melanoma
Mingqing Yuan, Yue Qiu, Li Zhang, Huile Gao & Qin He
Pages: 1171-1183
Published online: 03 Jun 2015
AbstractforTargeted delivery of transferrin and TAT co-modified liposomes encapsulating both paclitaxel and doxorubicin for melanoma | Full Text | References | PDF (2 MB)
  • 2723 Views
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Article
Tretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients
Salwa Abdel Rahman, Nevine Shawky Abdelmalak, Alia Badawi, Tahany Elbayoumy, Nermeen Sabry & Amany El Ramly
Pages: 1184-1193
Published online: 25 May 2015
AbstractforTretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients | Full Text | References | PDF (840.2 KB)
  • 3689 Views
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Article
Oleic acid derivative of polyethylenimine-functionalized proliposomes for enhancing oral bioavailability of extract of Ginkgo biloba
Bin Zheng, Shuang Yang, Chunyu Fan, Ye Bi, Lin Du, Lingzhi Zhao, Robert J. Lee, Lesheng Teng, Lirong Teng & Jing Xie
Pages: 1194-1203
Published online: 03 Dec 2015
AbstractforOleic acid derivative of polyethylenimine-functionalized proliposomes for enhancing oral bioavailability of extract of Ginkgo biloba | Full Text | References | PDF (1 MB)
  • 1062 Views
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Article
Liposomal fusidic acid as a potential delivery system: a new paradigm in the treatment of chronic plaque psoriasis
Sheetu Wadhwa, Bhupinder Singh, Gajanand Sharma, Kaisar Raza & Om Prakash Katare
Pages: 1204-1213
Published online: 23 Nov 2015
AbstractforLiposomal fusidic acid as a potential delivery system: a new paradigm in the treatment of chronic plaque psoriasis | Full Text | References | PDF (1.8 MB)
  • 3385 Views
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Article
Comparative study between simple and optimized liposomal dispersion of quetiapine fumarate for diffusion through nasal route
Pratik Upadhyay, Jatin Trivedi, Kilambi Pundarikakshudu & Navin Sheth
Pages: 1214-1221
Published online: 08 Dec 2015
AbstractforComparative study between simple and optimized liposomal dispersion of quetiapine fumarate for diffusion through nasal route | Full Text | References | PDF (1.2 MB)
  • 1588 Views
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Article
Preparation, characterization, and efficacy of thermosensitive liposomes containing paclitaxel
Zhi-Yuan Wang, Hui Zhang, Yang Yang, Xiang-Yang Xie, Yan-Fang Yang, Zhiping Li, Ying Li, Wei Gong, Fang-Lin Yu, Zhenbo Yang, Ming-Yuan Li & Xing-Guo Mei
Pages: 1222-1231
Published online: 15 Dec 2015
AbstractforPreparation, characterization, and efficacy of thermosensitive liposomes containing paclitaxel | Full Text | References | PDF (1.5 MB)
  • 2687 Views
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Article
Tumor neovasculature-targeted cationic PEGylated liposomes of gambogic acid for the treatment of triple-negative breast cancer
Ravi Doddapaneni, Ketan Patel, Ibtisam Hasan Owaid & Mandip Singh
Pages: 1232-1241
Published online: 24 Dec 2015
AbstractforTumor neovasculature-targeted cationic PEGylated liposomes of gambogic acid for the treatment of triple-negative breast cancer | Full Text | References | PDF (1.2 MB)
  • 1505 Views
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Article
Optimized permeation enhancer for topical delivery of 5-fluorouracil-loaded elastic liposome using Design Expert: part II
Afzal Hussain, Md Wasimul Haque, Sandeep Kumar Singh & Farhan Jalees Ahmed
Pages: 1242-1253
Published online: 24 Dec 2015
AbstractforOptimized permeation enhancer for topical delivery of 5-fluorouracil-loaded elastic liposome using Design Expert: part II | Full Text | References | PDF (2.7 MB)
  • 2226 Views
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Article
An alternative choice of lidocaine-loaded liposomes: lidocaine-loaded lipid–polymer hybrid nanoparticles for local anesthetic therapy
Jianguo Wang, Laizhu Zhang, Huimin Chi & Shilei Wang
Pages: 1254-1260
Published online: 16 Feb 2016
AbstractforAn alternative choice of lidocaine-loaded liposomes: lidocaine-loaded lipid–polymer hybrid nanoparticles for local anesthetic therapy | Full Text | References | PDF (695.9 KB)
  • 2498 Views
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Article
Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics
Sonali, Rahul Pratap Singh, Nitesh Singh, Gunjan Sharma, Mahalingam R. Vijayakumar, Biplob Koch, Sanjay Singh, Usha Singh, Debabrata Dash, Bajarangprasad L. Pandey & Madaswamy S. Muthu
Pages: 1261-1271
Published online: 31 Mar 2016
AbstractforTransferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics | Full Text | References | PDF (1.8 MB)
  • 4381 Views
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Article
Docetaxel prodrug liposomes for tumor therapy: characterization, in vitro and in vivo evaluation
Guolian Ren, Dan Liu, Weiling Guo, Menglin Wang, Chunnuan Wu, Mengran Guo, Xiaoyu Ai, Yongjun Wang & Zhonggui He
Pages: 1272-1281
Published online: 30 Mar 2016
AbstractforDocetaxel prodrug liposomes for tumor therapy: characterization, in vitro and in vivo evaluation | Full Text | References | PDF (2.2 MB) | Supplemental
  • 2675 Views
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Article
Pharmacokinetics and tissue distribution of docetaxel liposome mediated by a novel galactosylated cholesterol derivatives synthesized by lipase-catalyzed esterification in non-aqueous phase
Li-hua Luo, Pin-jing Zheng, Hua Nie, Yu-chao Chen, Dan Tong, Jin Chen & Yi Cheng
Pages: 1282-1290
Published online: 24 Nov 2014
AbstractforPharmacokinetics and tissue distribution of docetaxel liposome mediated by a novel galactosylated cholesterol derivatives synthesized by lipase-catalyzed esterification in non-aqueous phase | Full Text | References | PDF (369 KB)
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Review Article

Review
Lipid-based nanocarriers for breast cancer treatment – comprehensive review
Siddartha Venkata Talluri, Gowthamarajan Kuppusamy, Veera Venkata Satyanarayana Reddy Karri, Shashank Tummala & SubbaRao V. Madhunapantula
Pages: 1291-1305
Published online: 02 Oct 2015
AbstractforLipid-based nanocarriers for breast cancer treatment – comprehensive review | Full Text | References | PDF (927 KB)
  • 5608 Views
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Research Article

Article
Implications of formulation design on lipid-based nanostructured carrier system for drug delivery to brain
Sachin S. Salunkhe, Neela M. Bhatia & Manish S. Bhatia
Pages: 1306-1316
Published online: 31 Jul 2014
AbstractforImplications of formulation design on lipid-based nanostructured carrier system for drug delivery to brain | Full Text | References | PDF (601.1 KB) | Supplemental
  • 1519 Views
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Article
Formulation, characterization, and in vitro/vivo studies of aclacinomycin A-loaded solid lipid nanoparticles
Youpeng Jia, Jun Ji, Feng Wang, Liangang Shi, Jingbo Yu & Dong Wang
Pages: 1317-1325
Published online: 05 Nov 2014
AbstractforFormulation, characterization, and in vitro/vivo studies of aclacinomycin A-loaded solid lipid nanoparticles | Full Text | References | PDF (1.2 MB)
  • 1105 Views
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Article
Curcumin-loaded nanostructured lipid carriers (NLCs) for nasal administration: design, characterization, and in vivo study
Rohini G. Madane & Hitendra S. Mahajan
Pages: 1326-1334
Published online: 04 Nov 2014
AbstractforCurcumin-loaded nanostructured lipid carriers (NLCs) for nasal administration: design, characterization, and in vivo study | Full Text | References | PDF (999.5 KB)
  • 6852 Views
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Article
Development of lipid nanoparticles for a histone deacetylases inhibitor as a promising anticancer therapeutic
Tuan Hiep Tran, Duc Thanh Chu, Duy Hieu Truong, Jin Wook Tak, Jee-Heon Jeong, Van Luong Hoang, Chul Soon Yong & Jong Oh Kim
Pages: 1335-1343
Published online: 30 Dec 2014
AbstractforDevelopment of lipid nanoparticles for a histone deacetylases inhibitor as a promising anticancer therapeutic | Full Text | References | PDF (1.3 MB)
  • 1448 Views
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Article
Pharmacokinetics and tissue distribution study in mice of triptolide-loaded lipid emulsion and accumulation effect on pancreas
Xue Li, Yuling Mao, Kai Li, Tianyu Shi, Huimin Yao, Jianhua Yao & Shujun Wang
Pages: 1344-1354
Published online: 08 Apr 2015
AbstractforPharmacokinetics and tissue distribution study in mice of triptolide-loaded lipid emulsion and accumulation effect on pancreas | Full Text | References | PDF (1.3 MB)
  • 1681 Views
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Article
Albumin anchored docetaxel lipid nanoemulsion for improved targeting efficiency – preparation, characterization, cytotoxic, antitumor and in vivo imaging studies
Syed Muzammil Afzal, V. G. M Naidu, N. Harishankar & Veerabrahma Kishan
Pages: 1355-1363
Published online: 19 May 2015
AbstractforAlbumin anchored docetaxel lipid nanoemulsion for improved targeting efficiency – preparation, characterization, cytotoxic, antitumor and in vivo imaging studies | Full Text | References | PDF (1.3 MB)
  • 1279 Views
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Article
Co-delivery of baicalein and doxorubicin by hyaluronic acid decorated nanostructured lipid carriers for breast cancer therapy
Qian Liu, Jia Li, Gaobin Pu, Fang Zhang, Hongyan Liu & Yongqing Zhang
Pages: 1364-1368
Published online: 15 Apr 2015
AbstractforCo-delivery of baicalein and doxorubicin by hyaluronic acid decorated nanostructured lipid carriers for breast cancer therapy | Full Text | References | PDF (218 KB)
  • 2731 Views
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Article
Nanostructured lipid carriers based temozolomide and gene co-encapsulated nanomedicine for gliomatosis cerebri combination therapy
Zhihua Chen, Xianliang Lai, Shuxin Song, Xingen Zhu & Jianming Zhu
Pages: 1369-1373
Published online: 27 May 2015
AbstractforNanostructured lipid carriers based temozolomide and gene co-encapsulated nanomedicine for gliomatosis cerebri combination therapy | Full Text | References | PDF (354.4 KB)
  • 1744 Views
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Article
Targeted delivery of doxorubicin and vincristine to lymph cancer: evaluation of novel nanostructured lipid carriers in vitro and in vivo
Xiaoyuan Dong, Wen Wang, Hui Qu, Dong Han, Junmin Zheng & Guorui Sun
Pages: 1374-1378
Published online: 24 Jul 2015
AbstractforTargeted delivery of doxorubicin and vincristine to lymph cancer: evaluation of novel nanostructured lipid carriers in vitro and in vivo | Full Text | References | PDF (389.5 KB)
  • 1409 Views
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Article
Etoposide-loaded nanostructured lipid carriers for gastric cancer therapy
Hong Jiang, Lina Pei, Nannan Liu, Junsheng Li, Zhengrong Li & Shumei Zhang
Pages: 1379-1382
Published online: 10 Jul 2015
AbstractforEtoposide-loaded nanostructured lipid carriers for gastric cancer therapy | Full Text | References | PDF (197.3 KB)
  • 1404 Views
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Article
Nanostructured lipid carriers enhance the bioavailability and brain cancer inhibitory efficacy of curcumin both in vitro and in vivo
Yuhui Chen, Lizhen Pan, Ming Jiang, Dong Li & Lingjing Jin
Pages: 1383-1392
Published online: 11 Jun 2015
AbstractforNanostructured lipid carriers enhance the bioavailability and brain cancer inhibitory efficacy of curcumin both in vitro and in vivo | Full Text | References | PDF (2.3 MB)
  • 2993 Views
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Original Article

Article
Folate-modified, cisplatin-loaded lipid carriers for cervical cancer chemotherapy
Guilian Zhang, Fengying Liu, Erxia Jia, Lin Jia & Youzhong Zhang
Pages: 1393-1397
Published online: 13 Jul 2015
AbstractforFolate-modified, cisplatin-loaded lipid carriers for cervical cancer chemotherapy | Full Text | References | PDF (249.8 KB)
  • 1667 Views
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Research Article

Article
Lung cancer combination therapy: co-delivery of paclitaxel and doxorubicin by nanostructured lipid carriers for synergistic effect
Yawei Wang, Haiyan Zhang, Jing Hao, Bei Li, Ming Li & Wang Xiuwen
Pages: 1398-1403
Published online: 16 Jun 2015
AbstractforLung cancer combination therapy: co-delivery of paclitaxel and doxorubicin by nanostructured lipid carriers for synergistic effect | Full Text | References | PDF (497.5 KB)
  • 4376 Views
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Article
Novel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy
Shuxin Song, Guohua Mao, Jiansheng Du & Xingen Zhu
Pages: 1404-1408
Published online: 23 Jul 2015
AbstractforNovel RGD containing, temozolomide-loading nanostructured lipid carriers for glioblastoma multiforme chemotherapy | Full Text | References | PDF (340.9 KB)
  • 2749 Views
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Article
A new approach for treatment of precancerous lesions with curcumin solid–lipid nanoparticle-loaded gels: in vitro and clinical evaluation
Heba A. Hazzah, Ragwa M. Farid, Maha M. A. Nasra, Mennatallah Zakaria, Yousria Gawish, Magda A. El-Massik & Ossama Y. Abdallah
Pages: 1409-1419
Published online: 06 Jul 2015
AbstractforA new approach for treatment of precancerous lesions with curcumin solid–lipid nanoparticle-loaded gels: in vitro and clinical evaluation | Full Text | References | PDF (2.7 MB)
  • 3549 Views
  • 30 CrossRef citations
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Article
Curcumin-guided nanotherapy: a lipid-based nanomedicine for targeted drug delivery in breast cancer therapy
Mingzhen Lin, Lili Teng, Yang Wang, Jiaxin Zhang & Xianglian Sun
Pages: 1420-1425
Published online: 23 Jul 2015
AbstractforCurcumin-guided nanotherapy: a lipid-based nanomedicine for targeted drug delivery in breast cancer therapy | Full Text | References | PDF (542 KB)
  • 1776 Views
  • 41 CrossRef citations
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Article
Lipid composition has significant effect on targeted drug delivery properties of NGR-modified liposomes
Jun Chen, Aihua Lin, Pei Peng, Yong Wang, Wei Gu & Yiming Liu
Pages: 1426-1433
Published online: 16 Sep 2015
AbstractforLipid composition has significant effect on targeted drug delivery properties of NGR-modified liposomes | Full Text | References | PDF (892.4 KB)
  • 2281 Views
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Article
Galantamine-loaded solid–lipid nanoparticles for enhanced brain delivery: preparation, characterization, in vitro and in vivo evaluations
Shubham Misra, Kanwaljit Chopra, V. R. Sinha & Bikash Medhi
Pages: 1434-1443
Published online: 25 Sep 2015
AbstractforGalantamine-loaded solid–lipid nanoparticles for enhanced brain delivery: preparation, characterization, in vitro and in vivo evaluations | Full Text | References | PDF (1.3 MB)
  • 4230 Views
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Article
Development of an optimized hyaluronic acid-based lipidic nanoemulsion co-encapsulating two polyphenols for nose to brain delivery
Maha Nasr
Pages: 1444-1452
Published online: 24 Sep 2015
AbstractforDevelopment of an optimized hyaluronic acid-based lipidic nanoemulsion co-encapsulating two polyphenols for nose to brain delivery | Full Text | References | PDF (1,007.7 KB)
  • 5194 Views
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Article
Folic acid functionalized long-circulating co-encapsulated docetaxel and curcumin solid lipid nanoparticles: In vitro evaluation, pharmacokinetic and biodistribution in rats
Harish Pawar, Sunil Kumar Surapaneni, Kulbhushan Tikoo, Charan Singh, Rohani Burman, Manjinder Singh Gill & Sarasija Suresh
Pages: 1453-1468
Published online: 15 Feb 2016
AbstractforFolic acid functionalized long-circulating co-encapsulated docetaxel and curcumin solid lipid nanoparticles: In vitro evaluation, pharmacokinetic and biodistribution in rats | Full Text | References | PDF (2.4 MB)
  • 3656 Views
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Article
Lipids-based nanostructured lipid carriers (NLCs) for improved oral bioavailability of sirolimus
Qin Yu, Xiongwei Hu, Yuhua Ma, Yunchang Xie, Yi Lu, Jianping Qi, Li Xiang, Fengqian Li & Wei Wu
Pages: 1469-1475
Published online: 08 Mar 2016
AbstractforLipids-based nanostructured lipid carriers (NLCs) for improved oral bioavailability of sirolimus | Full Text | References | PDF (997.9 KB)
  • 2739 Views
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Article
Nanostructured lipid carrier in photodynamic therapy for the treatment of basal-cell carcinoma
Afreen Qidwai, Saba Khan, Shadab Md, Mohammad Fazil, Sanjula Baboota, Jasjeet K. Narang & Javed Ali
Pages: 1476-1485
Published online: 05 Apr 2016
AbstractforNanostructured lipid carrier in photodynamic therapy for the treatment of basal-cell carcinoma | Full Text | References | PDF (1.5 MB)
  • 2313 Views
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Article
Carvedilol nano lipid carriers: formulation, characterization and in-vivo evaluation
Akansha Mishra, Syed Sarim Imam, Mohammed Aqil, Abdul Ahad, Yasmin Sultana, Ameeduzzafar & Asgar Ali
Pages: 1486-1494
Published online: 05 Apr 2016
AbstractforCarvedilol nano lipid carriers: formulation, characterization and in-vivo evaluation | Full Text | References | PDF (886.3 KB)
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