Metabolomics in paediatric oncology: a potential still to be exploited

Laura SpigaNeonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, University of Cagliari CagliariItaly

Luigi AtzoriDepartment of Biomedical Sciences, University of Cagliari CagliariItaly

Antonio NotoNeonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, University of Cagliari CagliariItaly

Corrado MorettiPediatric Emergency and Intensive Care Unit, Department of Pediatrics, Sapienza University of Rome RomeItaly

Michele MussapDepartment of Laboratory Medicine, IRCCS San Martino-IST, University-Hospital Genova, GenovaItalyCorrespondence[email protected] [email protected]

Alice MasileNeonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, University of Cagliari CagliariItaly

Milena LussuNeonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, University of Cagliari CagliariItaly

Vassilios FanosNeonatal Intensive Care Unit, Puericulture Institute and Neonatal Section, University of Cagliari CagliariItaly

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Abstract

Oncology is a branch of medicine in rapid evolution in the attempt to find innovative methods for early diagnosis and a better understanding of tumoral processes leading to the development of new therapies. Metabolomics is the emerging discipline among the “omics” sciences which makes it possible to further expand our knowledge concerning cancer biology. Different studies have revealed the potential role of metabolomics in gaining an understanding of pathophysiological processes in cancer, improving tumor staging, characterizing tumors and searching for biomarkers predictive of therapeutic responses. However, to date there are few works aimed at gaining deeper insights into infantile oncology through metabolomics.

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Metabolomics in paediatric oncology: a potential still to be exploited

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Metabolomics in paediatric oncology: a potential still to be exploited

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