Financial & competing interests disclosure
This work was supported by the NIH (USA; GM089866 and CA176854) and the National Science Foundation (USA; CBET 0941055, 1510895). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.