Crucial role of inflammatory monocytes in antitumor immunity

Abstract

Although the role of myeloid cells in oncogenesis and tumor progression remains poorly understood, these cells are mainly ascribed with pro-tumor properties. We have recently unveiled a tumoricidal activity of inflammatory monocytes that can be counteracted by CD4⁺ regulatory T cells.

Keywords: :

• inflammatory monocytes
• inflammatory DCs
• ROS
• CD4⁺ regulatory T cells
• immunosurveillance
• melanoma
• vitiligo

Citation: Pommier A, Lucas B, Prevost-Blondel A. Crucial role of inflammatory monocytes in antitumor immunity. OncoImmunology 2013; 2:e26384; 10.4161/onci.26384

Disclosure of Potential Conflicts of Interest

No potential conflicts of interest were disclosed.