OncoImmunology, Volume 2, Issue 11 (2013)

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OncoImmunology, Volume 2, Issue 11 (2013)

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Editorial

Editorial
Immune effectors required for the therapeutic activity of vorinostat
Oliver Kepp, Lorenzo Galluzzi & Guido Kroemer
Article: e27157
Published online: 13 Nov 2013
First Page PreviewforImmune effectors required for the therapeutic activity of vorinostat | Full Text | References | PDF (214.3 KB)
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Editorial
An allogeneic NK cell line engineered to express chimeric antigen receptors
A novel strategy of cellular immunotherapy against cancer
Cécile Badoual, Pierre-Louis Bastier, Hélène Roussel, Marion Mandavit & Eric Tartour
Article: e27156
Published online: 14 Nov 2013
CitationforAn allogeneic NK cell line engineered to express chimeric antigen receptors | Full Text | References | PDF (180.1 KB)
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Original Research

Article
Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer
Andrea Schietinger, Ainhoa Arina, Rebecca B Liu, Sam Wells, Jianhua Huang, Boris Engels, Vytas Bindokas, Todd Bartkowiak, David Lee, Andreas Herrmann, David W Piston, Mikael J Pittet, P Charles Lin, Tomasz Zal & Hans Schreiber
Article: e26677
Published online: 04 Nov 2013
AbstractforLongitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer | Full Text | References | PDF (2.7 MB) | Supplemental
  • 2671 Views
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Article
Immunological responses to a multi-peptide vaccine targeting cancer-testis antigens and VEGFRs in advanced pancreatic cancer patients
Ryuji Okuyama, Atsushi Aruga, Takashi Hatori, Kazuyoshi Takeda & Masakazu Yamamoto
Article: e27010
Published online: 05 Nov 2013
AbstractforImmunological responses to a multi-peptide vaccine targeting cancer-testis antigens and VEGFRs in advanced pancreatic cancer patients | Full Text | References | PDF (515.4 KB) | Supplemental
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Article
Murine leukemia virus envelope gp70 is a shared biomarker for the high-sensitivity quantification of murine tumor burden
Francesca Scrimieri, David Askew, David J Corn, Saada Eid, Iuliana D Bobanga, Jaclyn A Bjelac, Matthew L Tsao, Frederick Allen, Youmna S Othman, Shih-Chung G Wang & Alex Y Huang
Article: e26889
Published online: 22 Nov 2013
AbstractforMurine leukemia virus envelope gp70 is a shared biomarker for the high-sensitivity quantification of murine tumor burden | Full Text | References | PDF (896.1 KB) | Supplemental
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Article
CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses
Zulkarnain Harfuddin, Shaqireen Kwajah, Adrian Chong Nyi Sim, Paul Anthony MacAry & Herbert Schwarz
Article: e26859
Published online: 11 Nov 2013
AbstractforCD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses | Full Text | References | PDF (1,014.4 KB) | Supplemental
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Brief Report

Brief Report
Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells
Giovanna Bossi, Andrew B Gerry, Samantha J Paston, Deborah H Sutton, Namir J Hassan & Bent K Jakobsen
Article: e26840
Published online: 21 Oct 2013
AbstractforExamining the presentation of tumor-associated antigens on peptide-pulsed T2 cells | Full Text | References | PDF (565.5 KB)
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Review

Review Article
Trial Watch: Lenalidomide-based immunochemotherapy
Michaela Semeraro, Erika Vacchelli, Alexander Eggermont , Jerome Galon, L Zitvogel, G Kroemer & Lorenzo Galluzzi
Article: e26494
Published online: 21 Oct 2013
AbstractforTrial Watch: Lenalidomide-based immunochemotherapy | PDF (603.6 KB)
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Review Article
Myeloid-derived suppressor cells
Cellular missiles to target tumors
Dinesh Chandra & Claudia Gravekamp
Article: e26967
Published online: 06 Nov 2013
AbstractforMyeloid-derived suppressor cells | Full Text | References | PDF (321.1 KB)
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Review Article
Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation
Lotte Spel, Jaap-Jan Boelens, Stefan Nierkens & Marianne Boes
Article: e26403
Published online: 21 Oct 2013
AbstractforAntitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation | PDF (671.7 KB)
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Review Article
Role of lymphocytes in liver cancer
Jana C Mossanen & Frank Tacke
Article: e26468
Published online: 21 Oct 2013
AbstractforRole of lymphocytes in liver cancer | Full Text | References | PDF (571.7 KB)
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Review Article
Role of non-classical MHC class I molecules in cancer immunosuppression
Grazyna Kochan, David Escors, Karine Breckpot & David Guerrero-Setas
Article: e26491
Published online: 21 Oct 2013
AbstractforRole of non-classical MHC class I molecules in cancer immunosuppression | PDF (570.5 KB)
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Review Article
The interplay between regulatory T cells and metabolism in immune regulation
Hu Zeng & Hongbo Chi
Article: e26586
Published online: 21 Oct 2013
AbstractforThe interplay between regulatory T cells and metabolism in immune regulation | Full Text | References | PDF (402.3 KB)
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Point of View

Immune response to mutant neo-antigens
Cancer's lessons for aging
Rory J Geyer, Rebecca Tobet, Richard D Berlin & Pramod K Srivastava
Article: e26382
Published online: 15 Oct 2013
AbstractforImmune response to mutant neo-antigens | Full Text | References | PDF (517.6 KB)
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Author's View

Non-replicating Toxoplasma gondii reverses tumor-associated immunosuppression
Barbara Fox, Kiah Sanders & David Bzik
Article: e26296
Published online: 09 Oct 2013
AbstractforNon-replicating Toxoplasma gondii reverses tumor-associated immunosuppression | PDF (368.2 KB)
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The relationship between malignant and tumor-associated cells provides a new strategy for targeted diagnosis and therapy
Xiaoling Lu, Jian He, Xia Li & yongxiang zhao
Article: e26295
Published online: 09 Oct 2013
AbstractforThe relationship between malignant and tumor-associated cells provides a new strategy for targeted diagnosis and therapy | PDF (496.9 KB)
  • 201 Views
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Survivin-3B promotes chemoresistance and immune escape by inhibiting caspase-8 and -6 in cancer cells
Frédérique Végran & Romain Boidot
Article: e26328
Published online: 09 Oct 2013
AbstractforSurvivin-3B promotes chemoresistance and immune escape by inhibiting caspase-8 and -6 in cancer cells | Full Text | References | PDF (304.3 KB)
  • 540 Views
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hTERT deficiency in naïve T cells affects lymphocyte homeostasis in myelodysplastic syndrome patients
Lili Yang, Erika A Eksioglu & Sheng Wei
Article: e26329
Published online: 09 Oct 2013
AbstractforhTERT deficiency in naïve T cells affects lymphocyte homeostasis in myelodysplastic syndrome patients | Full Text | References | PDF (267.2 KB)
  • 971 Views
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Tumor-derived lactate and myeloid-derived suppressor cells: Linking metabolism to cancer immunology
Zaheed Husain, Pankaj Seth & Vikas Sukhatme
Article: e26383
Published online: 09 Oct 2013
AbstractforTumor-derived lactate and myeloid-derived suppressor cells: Linking metabolism to cancer immunology | PDF (234.7 KB)
  • 819 Views
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Crucial role of inflammatory monocytes in antitumor immunity
Arnaud Pommier, Bruno Lucas & Armelle Prévost-Blondel
Article: e26384
Published online: 09 Oct 2013
AbstractforCrucial role of inflammatory monocytes in antitumor immunity | Full Text | References | PDF (378.3 KB)
  • 547 Views
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REG3β contributes to the immunosuppressive microenvironment of pancreatic cancer
Emma Folch-Puy
Article: e26404
Published online: 09 Oct 2013
AbstractforREG3β contributes to the immunosuppressive microenvironment of pancreatic cancer | Full Text | References | PDF (387.4 KB)
  • 606 Views
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Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI
Marie Vincent, Agnès Quéméner & Yannick Jacques
Article: e26441
Published online: 09 Oct 2013
AbstractforAntitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI | Full Text | References | PDF (316.5 KB)
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The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8+ T cells into innate-like effector cells with antitumor activity
Hing C Wong, Emily K Jeng & Peter R Rhode
Article: e26442
Published online: 09 Oct 2013
AbstractforThe IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8+ T cells into innate-like effector cells with antitumor activity | Full Text | References | PDF (469.5 KB)
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Monocyte-derived dendritic cells
Emerging players in the antitumor immune response
Sabine Kuhn & Franca Ronchese
Article: e26443
Published online: 09 Oct 2013
AbstractforMonocyte-derived dendritic cells | Full Text | References | PDF (354.2 KB)
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Oxysterols recruit tumor-supporting neutrophils within the tumor microenvironment
The many facets of tumor-derived oxysterols
Laura Raccosta, Raffaella Fontana, Catia Traversari & Vincenzo Russo
Article: e26469
Published online: 10 Oct 2013
AbstractforOxysterols recruit tumor-supporting neutrophils within the tumor microenvironment | Full Text | References | PDF (382.7 KB)
  • 602 Views
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Regulation of tumor-associated high-endothelial venules by dendritic cells
A new opportunity to promote lymphocyte infiltration into breast cancer?
Ludovic Martinet & Jean-Philippe Girard
Article: e26470
Published online: 10 Oct 2013
AbstractforRegulation of tumor-associated high-endothelial venules by dendritic cells | Full Text | References | PDF (323.9 KB)
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Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells: Re-tuning your CAR before hitting a rocky road
Liang-Chuan Wang, Matthew Riese, Edmund Moon & Steven M. Albelda
Article: e26492
Published online: 10 Oct 2013
AbstractforOvercoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells: Re-tuning your CAR before hitting a rocky road | PDF (292.2 KB)
  • 254 Views
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Local immunomodulation for cancer therapy: Providing treatment where needed
Marieke Fransen, Ferry Ossendorp, Ramon Arens & Cornelis J. Melief
Article: e26493
Published online: 10 Oct 2013
AbstractforLocal immunomodulation for cancer therapy: Providing treatment where needed | PDF (350.1 KB)
  • 417 Views
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FSTL1 promotes bone metastasis by causing immune dysfunction
Chie Kudo-Saito
Article: e26528
Published online: 10 Oct 2013
AbstractforFSTL1 promotes bone metastasis by causing immune dysfunction | Full Text | References | PDF (292.2 KB)
  • 1006 Views
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NK-cell fratricide: Dynamic crosstalk between NK and cancer cells
Kyohei Nakamura, Masafumi Nakayama, Mitsuko Kawano, Tomonori Ishii, Hideo Harigae & Kouetsu Ogasawara
Article: e26529
Published online: 10 Oct 2013
AbstractforNK-cell fratricide: Dynamic crosstalk between NK and cancer cells | PDF (276.5 KB)
  • 593 Views
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Dendritic cell-based vaccines
Shining the spotlight on signal 3
Gerald P Linette & Beatriz M Carreno
Article: e26512
Published online: 10 Oct 2013
AbstractforDendritic cell-based vaccines | Full Text | References | PDF (248.6 KB)
  • 673 Views
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Boosting leukemia-specific T cell responses in patients following stem cell transplantation
Ute E Burkhardt & Catherine J Wu
Article: e26587
Published online: 10 Oct 2013
AbstractforBoosting leukemia-specific T cell responses in patients following stem cell transplantation | Full Text | References | PDF (462.3 KB)
  • 514 Views
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Preventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination
Lee-Hwa Tai, Jiqing Zhang & Rebecca C. Auer
Article: e26618
Published online: 10 Oct 2013
AbstractforPreventing surgery-induced NK cell dysfunction and cancer metastases with influenza vaccination | PDF (339.8 KB)
  • 417 Views
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Membrane-anchored chemokine fusion proteins
A novel class of adjuvants for immunotherapy
Peter J Nelson & Niklas Muenchmeier
Article: e26619
Published online: 10 Oct 2013
AbstractforMembrane-anchored chemokine fusion proteins | Full Text | References | PDF (439.7 KB)
  • 611 Views
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