When breast cancer cells start to fend the educational process of NK cells off

Abstract

The notion of natural killer (NK)-cell education has recently emerged, and accumulating evidence indicates that the terminal differentiation of NK cells can be achieved in the periphery. This means that the proper function of these lymphocytes is dependent on their environment, opening a new door through which cancer cells can escape immunosurveillance.

Keywords::

• TGFβ
• breast cancer
• NK cells
• anti-tumor immunity
• education
• Immunosurveillance