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Journal of Taibah University for Science Volume 11, 2017 - Issue 6
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Review Article

Proficient synthesis of bioactive annulated pyrimidine derivatives: A reviewFootnote

Ajmal R. BhatDepartment of Chemistry, R.T.M. Nagpur University, Nagpur, 44003, IndiaCorrespondence[email protected] [email protected]
,
Rajendra S. DongreDepartment of Chemistry, R.T.M. Nagpur University, Nagpur, 44003, India
,
Gowhar A. NaikooDepartment of Mathematics and Sciences, College of Arts and Applied Sciences Dhofar University, Salalah, 2112509, Sultanate of Oman
,
Israr U. HassanDepartment of Mathematics and Sciences, College of Arts and Applied Sciences Dhofar University, Salalah, 2112509, Sultanate of Oman
&
Tabassum AraDepartment of Chemistry, N. I. T. Hazratbal, Kashmir, Srinagar, 190006, India
Pages 1047-1069 | Received 15 Jul 2015, Accepted 21 May 2017, Published online: 02 Nov 2018

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Ravindra R. Shinde & Mazahar Farooqui. (2022) One-Pot and Solvent Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones Using Recyclable Resin Purolite CT275DR as a Heterogeneous Catalyst via Three-Component Biginelli-Like Reactions. Polycyclic Aromatic Compounds 42:9, pages 6475-6484.
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Nitin Rode, Aafaq Tantray, Amruta Shelar, Rajendra Patil & Santosh Terdale. (2022) Amino acid ionic liquid-catalyzed synthesis, anti-Leishmania activity, molecular docking, molecular dynamic simulation, and ADME study of 3,4-dihydropyrimidin-2(1H)-(thio)ones. Synthetic Communications 52:2, pages 190-204.
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Articles from other publishers (27)

Sharmil N. Anjirwala & Saurabh K. Patel. (2024) Ceric ammonium nitrate catalyzed one-pot three-component microwave-assisted synthesis of indole-substituted fused pyrimidine and pyridine derivatives. Tetrahedron 155, pages 133883.
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Elshimaa Mohmed Eid. (2024) Sustainable Green Synthesis of Pyrimidine Derivatives: Review on Multicomponent Synthesis, Catalysts and Techniques. Current Organic Synthesis 21:2, pages 127-139.
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Navin B. Patel, Pratik N. Maisuria, Akash V. Gujarati & Divyesh K. Patel. (2024) Synthesis of Benzothiazole and Pyrimidine Based Fused Derivatives and Their Biological Evaluation. Russian Journal of Organic Chemistry 59:S1, pages S140-S149.
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Pradnya Patil, Afrin Ansari, Savita. J. Tauro & Sahaya Nadar. (2023) Green Recipes for Pyrimidine. Current Organic Synthesis 20:6, pages 678-705.
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Akshun Vyas, Bhaskar Sahu, Shelly Pathania, Nilay Kumar Nandi, Gaurav Chauhan, Vivek Asati & Bhupinder Kumar. (2022) An insight on medicinal attributes of pyrimidine scaffold: An updated review. Journal of Heterocyclic Chemistry 60:7, pages 1081-1121.
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Himanshu Kumar Singh, Arsala Kamal, Suresh Kumar Maury, Ambuj Kumar Kushwaha, Vandana Srivastava & Sundaram Singh. (2023) A green synthesis of pyrimido[4,5- b ]quinolines and pyrido[2,3- d ]pyrimidines via a mechanochemical approach . Organic & Biomolecular Chemistry 21:23, pages 4854-4862.
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Biswa Mohan Sahoo, Bimal Krishna Banik, Bera Venkata Varaha Ravi Kumar, Krishna Chandra Panda, Abhishek Tiwari, Varsha Tiwari, Sunil Singh & Manish Kumar. (2023) Microwave Induced Green Synthesis: Sustainable Technology for Efficient Development of Bioactive Pyrimidine Scaffolds. Current Medicinal Chemistry 30:9, pages 1029-1059.
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Mehul P. Parmar, Ruturajsinh M. Vala & Hitendra M. Patel. (2023) Importance of Hybrid Catalysts toward the Synthesis of 5 H -Pyrano[2,3- d ]pyrimidine-2-ones/2,4-diones (Thiones) . ACS Omega 8:2, pages 1759-1816.
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M. Akiful Haque, Akash Marathakam, Ritesh Rana, Samar J Almehmadi, Vishal B. Tambe, Manoj S. Charde, Fahadul Islam, Falak A. Siddiqui, Giulia Culletta, Anna Maria Almerico, Marco Tutone & Sharuk L. Khan. (2023) Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors. Molecules 28:2, pages 501.
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Sahaya Nadar & Tabassum Khan. (2021) Pyrimidine: An elite heterocyclic leitmotif in drug discovery‐synthesis and biological activity. Chemical Biology & Drug Design 100:6, pages 818-842.
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Mayur I. Morja & Kishor H. Chikhalia. (2022) Iron-catalyzed intermolecular cross-dehydrogenative C(sp3)–H/C(sp)–H coupling of pyrimidine bearing 4-thiazolidinones with terminal alkynes. Molecular Diversity 26:6, pages 3037-3045.
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Ayushi Sethiya, Priyanka Kalal, Pankaj Teli, Nusrat Sahiba, Jay Soni, Deepkumar Joshi & Shikha Agarwal. (2022) Highly efficient and diversity-oriented solvent-free synthesis of biologically active fused heterocycles using glycerol-based sulfonic acid. Research on Chemical Intermediates 48:11, pages 4711-4727.
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Wenjun Lan, Xuemei Tang, Jia Yu, Qiang Fei, Wenneng Wu, Pei Li & Heng Luo. (2022) Design, Synthesis, and Bioactivities of Novel Trifluoromethyl Pyrimidine Derivatives Bearing an Amide Moiety. Frontiers in Chemistry 10.
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M. S. Bhosale & K. Saravanan. (2022) Comparative synthetic study, in silico screening and biological evaluation of some substituted tetrahydropyrimidine-2-one derivatives as potential DHFR inhibitors. International journal of health sciences, pages 2814-2834.
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Ashish Anand, Netravati Khanapurmath, Manohar V. Kulkarni & Tayur N. Guru Row. (2022) Biheterocyclic Coumarins: A Simple Yet Versatile Resource for Futuristic Design and Applications in Bio-molecular and Material Chemistry. Current Organic Chemistry 26:5, pages 444-506.
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A. A. Babushkina, Yu. L. Piterskaya, A. A. Shtro, Yu. V. Nikolaeva, A. V. Galochkina, A. M. Klabukov & D. M. Egorov. (2022) Synthesis, Phosphonylation, and Anti-Viral Activity of Some 6-Aryl-5-cyano-2-thiouracils. Russian Journal of General Chemistry 92:1, pages 18-23.
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Asmaa H. Mohamed, Hager S. Abdelmeged, Raafat M. Shaker & Fathy F. Abdel‐Latif. (2021) One‐pot three‐component reaction; synthesis of new symmetrically bridge 4,4′‐(1,4‐phenylene)di‐pyrimidines under solvent free conditions. Journal of Heterocyclic Chemistry 58:12, pages 2372-2380.
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Ayushi Sethiya, Jay Soni, Anu Manhas, Prakash Chandra Jha & Shikha Agarwal. (2021) Green and highly efficient MCR strategy for the synthesis of pyrimidine analogs in water via C–C and C–N bond formation and docking studies. Research on Chemical Intermediates 47:11, pages 4477-4496.
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Atefeh Bakhtiari, Javad Safaei‐Ghomi & Raheleh Teymuri. (2021) Green sonosynthesis of pyridopyrimidines using heterogeneous Pd‐containing catalysts anchored on a hybrid organic–inorganic surface of SBA ‐15 . Journal of the Chinese Chemical Society 68:9, pages 1748-1760.
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Saba Farooq & Zainab Ngaini. (2021) One‐pot and two‐pot methods for chalcone derived pyrimidines synthesis and applications . Journal of Heterocyclic Chemistry 58:6, pages 1209-1224.
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Fatma Bassyouni, Mohammad Tarek, Abeer Salama, Bassant Ibrahim, Sawsan Salah El Dine, Nemat Yassin, Amina Hassanein, Maysa Moharam & Mohamed Abdel-Rehim. (2021) Promising Antidiabetic and Antimicrobial Agents Based on Fused Pyrimidine Derivatives: Molecular Modeling and Biological Evaluation with Histopathological Effect. Molecules 26:8, pages 2370.
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Sumaiya Tabassum, K.R. Sunaja Devi & Santhosh Govindaraju. (2021) Nano ZnO@PEG catalyzed one-pot green synthesis of pyrano[2,3-d]pyrimidines in ethanol via one-pot multicomponent approach. Materials Today: Proceedings 45, pages 3716-3721.
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Mohammed Hussen Bule, Roghaieh Esfandyari, Tadesse Bekele Tafesse, Mohsen Amini, Mohammad Ali Faramarzi & Mohammad Abdollahi. (2020) Synthesis, Molecular Docking and α-Glucosidase Inhibitory Activity Study of 2,4,6-triaryl Pyrimidine Derivatives. Letters in Drug Design & Discovery 17:10, pages 1216-1226.
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Rashmi Sharma & Anil Kumar. 2020. Green Sustainable Process for Chemical and Environmental Engineering and Science. Green Sustainable Process for Chemical and Environmental Engineering and Science 43 70 .
Mohamed A. Abozeid, Mohamed R. El‐Kholany, Laila A. Abouzeid, Abdel‐Rahman H. Abdel‐Rahman & El‐Sayed I. El‐Desoky. (2019) Synthesis and Computational Analysis of New Antioxidant and Antimicrobial Angular Chromenopyrimidines. Journal of Heterocyclic Chemistry 56:10, pages 2922-2933.
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Nguyen Dinh Thanh, Do Son Hai, Nguyen Thi Thu Ha, Do Tien Tung, Cao Thi Le, Hoang Thi Kim Van, Vu Ngoc Toan, Duong Ngoc Toan & Le Hai Dang. (2019) Synthesis, biological evaluation and molecular docking study of 1,2,3-1H-triazoles having 4H-pyrano[2,3-d]pyrimidine as potential Mycobacterium tuberculosis protein tyrosine phosphatase B inhibitors. Bioorganic & Medicinal Chemistry Letters 29:2, pages 164-171.
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Ricardo D. Enriz, Rodrigo D. Tosso, Sebastián A. Andújar, Nuria Cabedo, Diego Cortés, Manuel Nogueras, Justo Cobo, Didier F. Vargas & Jorge Trilleras. (2018) Indole-substituted 2,4-diamino-5,8-dihydropyrido[2,3-d]pyrimidines from one-pot process and evaluation of their ability to bind dopamine receptors. Tetrahedron 74:49, pages 7047-7057.
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