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Research Article

Effects of Intratympanic Injection of Steroids on Changes in Rat Inner Ear Aquaporin Expression

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Pages 600-606 | Published online: 08 Jul 2009

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Read on this site (6)

Tatjana Tomanovic. (2023) Intratympanic dexamethasone in Manières disease and symptom control. Acta Oto-Laryngologica 143:8, pages 681-686.
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Jin Su Park, So Yean Kim & Min-Beom Kim. (2018) Effect of intratympanic steroid injection in light cupula. Acta Oto-Laryngologica 138:9, pages 769-774.
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Hironao Otake, Hiroshi Yamamoto, Masaaki Teranishi, Michihiko Sone & Tsutomu Nakashima. (2009) Cochlear blood flow during occlusion and reperfusion of the anterior inferior cerebellar artery – effect of topical application of dexamethasone to the round window. Acta Oto-Laryngologica 129:2, pages 127-131.
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Daizo Taguchi, Taizo Takeda, Akinobu Kakigi, Teruhiko Okada, Rie Nishioka & Hiroya Kitano. (2008) Expression and immunolocalization of aquaporin-6 (Aqp6) in the rat inner ear. Acta Oto-Laryngologica 128:8, pages 832-840.
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Munehisa Fukushima, Tadashi Kitahara, Yuka Fuse, Yoshihiro Uno, Katsumi Doi & Takeshi Kubo. (2004) Changes in aquaporin expression in the inner ear of the rat after i.p. injection of steroids. Acta Oto-Laryngologica 124:sup553, pages 13-18.
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Vincent Couloigner, Dominique Berrebi, Marie Teixeira, Régine Paris, Agnès Florentin, Alexis Bozorg Grayeli, Françoise Cluzeaud, Olivier Sterkers, Michel Peuchmaur & Evelyne Ferrary. (2004) Aquaporin-2 in the human endolymphatic sac. Acta Oto-Laryngologica 124:4, pages 449-453.
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Articles from other publishers (40)

Robin Mom, Stéphane Réty, Vincent Mocquet & Daniel Auguin. (2023) In silico pharmacological study of AQP2 inhibition by steroids contextualized to Ménière’s disease treatments. Frontiers in Neurology 14.
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Dao-Gong Zhang, Wen-Qian Yu, Jia-Hui Liu, Li-Gang Kong, Na Zhang, Yong-Dong Song, Xiao-Fei Li, Zhao-Min Fan, Ya-Feng Lyu, Na Li & Hai-Bo Wang. (2023) Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model. Nature Communications 14:1.
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Robin Mom, Julien Robert-Paganin, Thierry Mom, Christian Chabbert, Stéphane Réty & Daniel Auguin. (2022) A Perspective for Ménière’s Disease: In Silico Investigations of Dexamethasone as a Direct Modulator of AQP2. Biomolecules 12:4, pages 511.
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Lacey Nelson, Braeden Lovett, J. Dixon Johns, Shoujun Gu, Dongseok Choi, Dennis Trune & Michael Hoa. (2022) In silico Single-Cell Analysis of Steroid-Responsive Gene Targets in the Mammalian Cochlea. Frontiers in Neurology 12.
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Weiming Hao, Huiqian Yu & Huawei Li. (2021) Effects of intratympanic gentamicin and intratympanic glucocorticoids in Ménière’s disease: a network meta-analysis. Journal of Neurology 269:1, pages 72-86.
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Ji-A Kim & Sung-Won Choi. (2021) A Review of Intratympanic Corticosteroid Injection for Meniere’s Disease. Journal of Clinical Otolaryngology Head and Neck Surgery 32:3, pages 189-201.
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Su-lin Zhang, E. Tian, Wen-chao Xu, Yu-ting Zhu & Wei-jia Kong. (2020) Light Cupula: To Be Or Not to Be?. Current Medical Science 40:3, pages 455-462.
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Anita Bhandari & Satish Jain. (2019) Early Intratympanic Methylprednisolone in Sudden SNHL: A Frequency-wise Analysis. Indian Journal of Otolaryngology and Head & Neck Surgery 71:3, pages 390-395.
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Jaimin Patel, Mikhaylo Szczupak, Suhrud Rajguru, Carey Balaban & Michael E. Hoffer. (2019) Inner Ear Therapeutics: An Overview of Middle Ear Delivery. Frontiers in Cellular Neuroscience 13.
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N. V. Boiko, V. V. Kiselev, T. S. Kolmakova, I. V. Stagnieva & V. V. Bykova. (2018) The influence of corticosteroids on the frequency of vestibular crises. Vestnik otorinolaringologii 83:6, pages 27.
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Mitesh Patel. (2017) Intratympanic corticosteroids in Ménière's disease: A mini-review. Journal of Otology 12:3, pages 117-124.
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Y Dai, L Lu, J Hou, X Yang, H Li, Y Yang & W She. (2017) Intratympanic methylprednisolone perfusion as a salvage treatment for profound idiopathic sudden sensorineural hearing loss. The Journal of Laryngology & Otology 131:5, pages 404-410.
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Mejd Jumaily, Farhoud Faraji & Anthony A. Mikulec. (2017) Intratympanic Triamcinolone and Dexamethasone in the Treatment of Ménière's Syndrome. Otology & Neurotology 38:3, pages 386-391.
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Mitesh Patel, Kiran Agarwal, Qadeer Arshad, Mohamed Hariri, Peter Rea, Barry M Seemungal, John F Golding, Jonny P Harcourt & Adolfo M Bronstein. (2016) Intratympanic methylprednisolone versus gentamicin in patients with unilateral Ménière's disease: a randomised, double-blind, comparative effectiveness trial. The Lancet 388:10061, pages 2753-2762.
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Zachary Farhood & Paul R. Lambert. (2016) The physiologic role of corticosteroids in Ménière's disease. American Journal of Otolaryngology 37:5, pages 455-458.
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Naoya Egami, Shinichi Iwasaki, Chisato Fujimoto, Atsushi Kinoshita, Teru Kamogashira, Munetaka Ushio, Keiko Sugasawa & Tatsuya Yamasoba. (2015) Intratympanic steroid injection for the treatment of intractable vertigo in Meniere's disease.. Equilibrium Research 74:4, pages 290-298.
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Ryan A. Crane, Marc Camilon, Shaun Nguyen & Ted A. Meyer. (2014) Steroids for treatment of sudden sensorineural hearing loss: A meta‐analysis of randomized controlled trials. The Laryngoscope 125:1, pages 209-217.
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CHENJIE YU, XINYAN CUI, FENG CHEN, JUN YANG, XIAOYUN QIAN & XIA GAO. (2013) Effect of glucocorticoids on aquaporin-1 in guinea pigs with otitis media with effusion. Experimental and Therapeutic Medicine 5:6, pages 1589-1592.
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Setsuko Morinaka-Nakamura. (2013) Vertigo and acid-base imbalance. Equilibrium Research 72:3, pages 145-155.
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Raphael Richard Ciuman. (2013) Inner ear symptoms and disease: Pathophysiological understanding and therapeutic options. Medical Science Monitor 19, pages 1195-1210.
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Setsuko Morinaka-Nakamura. (2012) Vertigo and acid-base balance. Equilibrium Research 71:3, pages 182-184.
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Stefan K. Plontke. 2011. Vertigo — Kontroverses und Bewährtes. Vertigo — Kontroverses und Bewährtes 175 181 .
R. Nishioka, T. Takeda, A. Kakigi, T. Okada, S. Takebayashi, D. Taguchi, M. Nishimura & M. Hyodo. (2010) Expression of aquaporins and vasopressin type 2 receptor in the stria vascularis of the cochlea. Hearing Research 260:1-2, pages 11-19.
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Paola Perin, Simona Tritto, Laura Botta, Jacopo Maria Fontana, Giulia Gastaldi, Sergio Masetto, Marisa Tosco & Umberto Laforenza. (2010) Aquaporin-6 Expression in the Cochlear Sensory Epithelium Is Downregulated by Salicylates. Journal of Biomedicine and Biotechnology 2010, pages 1-8.
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Iacopo Dallan, Andrea De Vito, Bruno Fattori, Augusto Pietro Casani, Erica Panicucci, Stefano Berrettini, Manuela Marchetti & Andrea Nacci. (2010) Intratympanic Methylprednisolone in Refractory Sudden Hearing Loss. Otology & Neurotology 31:1, pages 25-30.
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M Topak, A Sahin-Yilmaz, T Ozdoganoglu, H B Yilmaz, M Ozbay & M Kulekci. (2009) Intratympanic methylprednisolone injections for subjective tinnitus. The Journal of Laryngology & Otology 123:11, pages 1221-1225.
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Seok Min Hong, Chan Hum Park & Jun Ho Lee. (2009) Hearing outcomes of daily intratympanic dexamethasone alone as a primary treatment modality for ISSHL. Otolaryngology–Head and Neck Surgery 141:5, pages 579-583.
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R R Ciuman. (2008) Stria vascularis and vestibular dark cells: characterisation of main structures responsible for inner-ear homeostasis, and their pathophysiological relations. The Journal of Laryngology & Otology 123:2, pages 151-162.
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Taizo Takeda & Daizo Taguchi. 2009. Aquaporins. Aquaporins 171 184 .
Mohamed Hamid & Dennis Trune. (2008) Issues, indications, and controversies regarding intratympanic steroid perfusion. Current Opinion in Otolaryngology & Head & Neck Surgery 16:5, pages 434-440.
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Philip A. Bird, Evan J. Begg, Mei Zhang, Allan T. Keast, Daran P. Murray & Thomas J. Balkany. (2007) Intratympanic Versus Intravenous Delivery of Methylprednisolone to Cochlear Perilymph. Otology & Neurotology 28:8, pages 1124-1130.
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Jixiang Chen & Hui Li. (2007) Effects of dexamthasone with different doses on aquaporin-4 in brain of intracerebral hemorrhage rats. Journal of Nanjing Medical University 21:5, pages 302-306.
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David S. Haynes, Matthew O'Malley, Seth Cohen, Kenneth Watford & Robert F. Labadie. (2009) Intratympanic Dexamethasone for Sudden Sensorineural Hearing Loss After Failure of Systemic Therapy. The Laryngoscope 117:1, pages 3-15.
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M. J. R. C Alles, M. A. Gaag & R. J. Stokroos. (2006) Intratympanic steroid therapy for inner ear diseases, a review of the literature. European Archives of Oto-Rhino-Laryngology 263:9, pages 791-797.
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Christopher A. Hargunani, J. Beth Kempton, Jacqueline M. DeGagne & Dennis R. Trune. (2006) Intratympanic Injection of Dexamethasone. Otology & Neurotology 27:4, pages 564-569.
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Christopher A. Hargunani, J. Beth Kempton, Jacqueline M. DeGagne & Dennis R. Trune. (2006) Intratympanic Injection of Dexamethasone. Otology & Neurotology 27:4, pages 564-569.
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Huishu Liu & E Marelyn Wintour. (2005) Aquaporins in development – a review. Reproductive Biology and Endocrinology 3:1.
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Avik Banerjee & Lorne S. Parnes. (2004) The biology of intratympanic drug administration and pharmacodynamics of round window drug absorption. Otolaryngologic Clinics of North America 37:5, pages 1035-1051.
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Piero Portincasa, Antonio Moschetta, Amelia Mazzone, Giuseppe Palasciano, Maria Svelto & Giuseppe Calamita. (2003) Water handling and aquaporins in bile formation: recent advances and research trends. Journal of Hepatology 39:5, pages 864-874.
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Taizo Takeda, Shoichi Sawada, Setsuko Takeda, Hiroya Kitano, Mikio Suzuki, Akinobu Kakigi & Shunji Takeuchi. (2003) The effects of V2 antagonist (OPC-31260) on endolymphatic hydrops. Hearing Research 182:1-2, pages 9-18.
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