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Original Articles

Effect of Phosgene on Rat Lungs after Single High-Level Exposure

I. Biochemical Alterations

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Pages 271-277 | Published online: 16 Apr 2013

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Stephen T. Hobson, Richard A. Richieri & Missag H. Parseghian. (2021) Phosgene: toxicology, animal models, and medical countermeasures. Toxicology Mechanisms and Methods 31:4, pages 293-307.
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Dorian S. Olivera, Heidi Hoard-Fruchey & Alfred M. Sciuto. (2017) Evaluation of an in vitro screening model to assess phosgene inhalation injury. Toxicology Mechanisms and Methods 27:1, pages 45-51.
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Jürgen Pauluhn. (2011) Acute nose-only inhalation exposure of rats to di- and triphosgene relative to phosgene. Inhalation Toxicology 23:2, pages 65-73.
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Annetta Watson, Linda Hall, Ellen Raber, VeroniqueD. Hauschild, Fredrick Dolislager, AdamH. Love & M. Leslie Hanna. (2011) Developing Health-Based Pre-Planning Clearance Goals for Airport Remediation Following Chemical Terrorist Attack: Introduction and Key Assessment Considerations. Human and Ecological Risk Assessment: An International Journal 17:1, pages 2-56.
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J. Pauluhn, A. Carson, D. L. Costa, T. Gordon, U. Kodavanti, J. A. Last, M. A. Matthay, K. E. Pinkerton & A. M. Sciuto. (2007) Workshop Summary: Phosgene-Induced Pulmonary Toxicity Revisited: Appraisal of Early and Late Markers of Pulmonary Injury From Animal Models With Emphasis on Human Significance. Inhalation Toxicology 19:10, pages 789-810.
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Alfred M. Sciuto & Holcombe H. Hurt. (2004) Therapeutic Treatments of Phosgene-Induced Lung Injury. Inhalation Toxicology 16:8, pages 565-580.
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Alfred M. Sciuto, Theodore S. Moran. (1999) BHA DIET ENHANCES THE SURVIVAL OF MICE EXPOSED TO PHOSGENE: The Effect of BHA on Glutathione Levels in the Lung. Inhalation Toxicology 11:9, pages 855-871.
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Alfred M. Sciuto, Paul T. Strickland, Thomas P. Kennedy & Gail H. Gurtner. (1997) Postexposure Treatment with Aminophylline Protects Against Phosgene-Induced Acute Lung Injury. Experimental Lung Research 23:4, pages 317-332.
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JeffreyP. Ehrlich & GaryR. Burleson. (1991) Enhanced and prolonged pulmonary influenza virus infection following phosgene inhalation. Journal of Toxicology and Environmental Health 34:2, pages 259-273.
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Michael C. Madden, Mitchell Friedrnan, Lynette L. Keyes, Hillel S. Koren & Gary R. Burleson. (1991) Effects of Phosgene Exposure on Lung Arachidonic Acid Metabolism. Inhalation Toxicology 3:1, pages 73-90.
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Serafino Franch & GaryE. Hatch. (1986) Pulmonary biochemical effects of inhaled phosgene in rats. Journal of Toxicology and Environmental Health 19:3, pages 413-423.
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R. Pawlowski & M. F Frosolono. (1977) Effect of Phosgene on Rat Lungs after Single High-Level Exposure. Archives of Environmental Health: An International Journal 32:6, pages 278-283.
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Articles from other publishers (7)

Wesley W. Holmes, Brian M. Keyser, Danielle C. Paradiso, Radharaman Ray, Devon K. Andres, Betty J. Benton, Cristin C. Rothwell, Heidi M. Hoard-Fruchey, James F. Dillman, Alfred M. Sciuto & Dana R. Anderson. (2016) Conceptual approaches for treatment of phosgene inhalation-induced lung injury. Toxicology Letters 244, pages 8-20.
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Robert L. Maynard & Robert P. Chilcott. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Alfred Sciuto. 2005. Inhalation Toxicology, Second Edition. Inhalation Toxicology, Second Edition 457 483 .
R. F. R. Brown, B. J. A. Jugg, F. M. J. Harban, Z. Ashley, C. E. Kenward, J. Platt, A. Hill, P. Rice & P. E. Watkins. (2002) Pathophysiological responses following phosgene exposure in the anaesthetized pig. Journal of Applied Toxicology 22:4, pages 263-269.
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Peter H. Wald & John R. Balmes. (2016) Respiratory Effects of Short-Term, High-Intensity Toxic Inhalations: Smoke, Gases, and Fumes. Journal of Intensive Care Medicine 2:5, pages 260-278.
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William D. Currie, Gary E. Hatch & Michael F. Frosolono. (2006) Changes in lung ATP concentration in the rat after low‐level phosgene exposure. Journal of Biochemical Toxicology 2:2, pages 105-114.
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M.F. Frosolono. (2016) Prophylactic and Antidotal Effects of Hexamethylenetetramine Against Phosgene Poisoning in Rabbits. Toxicology and Industrial Health 1:2, pages 101-116.
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