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Research Article

A meta-analysis of cerebrovascular disease and hyperhomocysteinaemia

Pages 491-500 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Qun Wang, Minghang Liu, Kai Zhao, Xinghua Xu, JiaShu Zhang & BaiNan Xu. (2023) Hyperhomocysteinemia increases the risk of vertebrobasilar dissecting aneurysm among the male Han Chinese population: a retrospective case-control study. International Journal of Neuroscience 0:0, pages 1-7.
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Steven F Werder. (2010) Cobalamin deficiency, hyperhomocysteinemia, and dementia. Neuropsychiatric Disease and Treatment 6, pages 159-195.
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Jutta Dierkes, Claus Luley & Sabine Westphal. (2007) Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels. Vascular Health and Risk Management 3:1, pages 99-108.
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L.-K. Yang, K.-C. Wong, M.-Y. Wu, S.-L. Liao, C.-S. Kuo & R.-F. S. Huang. (2007) Correlations Between Folate, B12, Homocysteine Levels, and Radiological Markers of Neuropathology in Elderly Post-Stroke Patients. Journal of the American College of Nutrition 26:3, pages 272-278.
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S. Raeder, S. Landaas, K. Laake, T. Lyberg & K. Engedal. (2006) Homocysteine measurements in geriatric patients. Scandinavian Journal of Clinical and Laboratory Investigation 66:4, pages 309-316.
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Articles from other publishers (50)

丹 王. (2024) Meta-Analysis of the Relationship between Homocysteine and White Matter Lesions. Advances in Clinical Medicine 14:04, pages 1143-1153.
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J. Eric Ahlskog. (2023) Levodopa, homocysteine and Parkinson's disease: What's the problem?. Parkinsonism & Related Disorders 109, pages 105357.
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Pramod Kumar, Aparna Mishra, Manoj K Prasad, Vivek Verma & Amit Kumar. (2022) Relationship of Methylenetetrahydrofolate Reductase (MTHFR) C677T Variation With Susceptibility of Patients With Ischemic Stroke: A Meta-Analysis. Cureus.
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Qun Wang, JiaShu Zhang, Kai Zhao & BaiNan Xu. (2019) Hyperhomocysteinemia is an independent risk factor for intracranial aneurysms: a case-control study in a Chinese Han population. Neurosurgical Review 43:4, pages 1127-1134.
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Ching-Yu Julius Chen, Tzu-Ching Yang, Christopher Chang, Shao-Chun Lu & Po-Yuan Chang. (2018) Homocysteine is a bystander for ST-segment elevation myocardial infarction: a case-control study. BMC Cardiovascular Disorders 18:1.
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Jin-Rui Ren, Shao-Hua Ren, Bo Ning, Jun Wu, Yong Cao, Xin-Min Ding, Zi-Gang Zhen, Xu-Dong Hao & Shuo Wang. (2017) Hyperhomocysteinemia as a Risk Factor for Saccular Intracranial Aneurysm: A Cohort Study in a Chinese Han Population. Journal of Stroke and Cerebrovascular Diseases 26:12, pages 2720-2726.
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Jibo Zhao, Ping Du, Xingyuan Sun & Hongbin Liu. (2017) Development of Electrochemical Sensor for Homocysteine Determination as a Cerebrovascular Disease Biomarker. International Journal of Electrochemical Science 12:9, pages 8642-8650.
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Yanli Song, Bohong Li, Chunjuan Wang, Penglian Wang, Xiang Gao & Gaifen Liu. (2016) Association between 5,10-Methylenetetrahydrofolate Reductase C677T Gene Polymorphism and Risk of Ischemic Stroke: A Meta-analysis. Journal of Stroke and Cerebrovascular Diseases 25:3, pages 679-687.
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Giel-Jan de Vries, Anja Lok, Roel Mocking, Johanna Assies, Aart Schene & Miranda Olff. (2015) Altered one-carbon metabolism in posttraumatic stress disorder. Journal of Affective Disorders 184, pages 277-285.
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Yusheng He, Yunxia Li, Yuhui Chen, Liang Feng & Zhiyu Nie. (2014) Homocysteine level and risk of different stroke types: A meta-analysis of prospective observational studies. Nutrition, Metabolism and Cardiovascular Diseases 24:11, pages 1158-1165.
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Shan Kang, Yili Wu, Lingling Liu, Xinxin Zhao & Dongfeng Zhang. (2014) Association of the A1298C polymorphism in MTHFR gene with ischemic stroke. Journal of Clinical Neuroscience 21:2, pages 198-202.
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Amit Kumar, Ram Sagar, Pradeep Kumar, Jitendra K Sahu, Ashoo Grover, Achal K Srivastava, S Vivekanandhan & Kameshwar Prasad. (2013) Identification of genetic contribution to ischemic stroke by screening of single nucleotide polymorphisms in stroke patients by using a case control study design. BMC Neurology 13:1.
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Jiunn-Tay Lee, Giia-Sheun Peng, Shao-Yuan Chen, Chang-Hung Hsu, Chun-Chieh Lin, Chun-An Cheng, Yaw-Don Hsu & Jiann-Chyun Lin. (2013) Homocysteine induces cerebral endothelial cell death by activating the acid sphingomyelinase ceramide pathway. Progress in Neuro-Psychopharmacology and Biological Psychiatry 45, pages 21-27.
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Najiba Fekih-Mrissa, Meriem Mrad, Sarra Klai, Malek Mansour, Brahim Nsiri, Nasreddine Gritli & Ridha Mrissa. (2013) Methylenetetrahydrofolate Reductase (C677T and A1298C) Polymorphisms, Hyperhomocysteinemia, and Ischemic Stroke in Tunisian Patients. Journal of Stroke and Cerebrovascular Diseases 22:4, pages 465-469.
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Rui Ding, Shilei Lin & Daojun Chen. (2012) The association of Cystathionine β Synthase (CBS) T833C polymorphism and the risk of stroke: A meta-analysis. Journal of the Neurological Sciences 312:1-2, pages 26-30.
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Hui-Qi Low, Christopher P. L. H. Chen, Katherine Kasiman, Anbupalam Thalamuthu, Seok-Shin Ng, Jia-Nee Foo, Hui-Meng Chang, Meng-Cheong Wong, E-Shyong Tai & Jianjun Liu. (2011) A Comprehensive Association Analysis of Homocysteine Metabolic Pathway Genes in Singaporean Chinese with Ischemic Stroke. PLoS ONE 6:9, pages e24757.
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Johan Hultdin, Bethany Van Guelpen, Anna Winkvist, Göran Hallmans, Lars Weinehall, Birgitta Stegmayr & Torbjörn K. Nilsson. (2011) Prospective study of first stroke in relation to plasma homocysteine and MTHFR 677C>T and 1298A>C genotypes and haplotypes – evidence for an association with hemorrhagic stroke. Clinical Chemistry and Laboratory Medicine 49:9.
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A. W. M. Janssen, F. E. de Leeuw & M. C. H. Janssen. (2010) Risk factors for ischemic stroke and transient ischemic attack in patients under age 50. Journal of Thrombosis and Thrombolysis 31:1, pages 85-91.
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Zhen-Guang Li, Zhan-Cai Yu, Yong-Peng Yu, Wei-Ping Ju, Dao-Zhen Wang, Xia Zhan, Xi-Juan Wu & Li Zhou. (2010) Lysophosphatidic Acid Level and the Incidence of Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation. International Journal of Molecular Sciences 11:10, pages 3988-3998.
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E. Malvino, D. Mcloughlin & O. López Gastón. (2009) Trombofilias y trombosis venosa cerebral en el puerperio. Clínica e Investigación en Ginecología y Obstetricia 36:5, pages 186-189.
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Rodica E. Petrea & Sudha Seshadri. 2009. Glutathione and Sulfur Amino Acids in Human Health and Disease. Glutathione and Sulfur Amino Acids in Human Health and Disease 441 469 .
Rajinder K. Dhamija, P. Gaba, S. Arora, A. Kaintura, M. Kumar & J. Bhattacharjee. (2009) Homocysteine and lipoprotein (a) correlation in ischemic stroke patients. Journal of the Neurological Sciences 281:1-2, pages 64-68.
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Anders Wallin & Tuula Pirttilä. 2009. Vascular Cognitive Impairment in Clinical Practice. Vascular Cognitive Impairment in Clinical Practice 77 92 .
MJ Haddaway & MWJ Davie. (2009) Bone health in stroke. Reviews in Clinical Gerontology 18:03, pages 199.
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Nongnuch Sirachainan, Werasak Sasanakul, Anannit Visudtibhan, Pornsri Tapanapruksakul, Pimlak Charoenkwan, Praguywan Kadegasem, Umaporn Udomsubpayakul & Ampaiwan Chuansumrit. (2008) The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children. Thrombosis Research 122:1, pages 33-37.
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Maged Y.Z. Youssef, Olusegun A. Mojiminiyi & Nabila A. Abdella. (2007) Plasma concentrations of C-reactive protein and total homocysteine in relation to the severity and risk factors for cerebrovascular disease. Translational Research 150:3, pages 158-163.
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Aliyah Rahemtullah & Elizabeth M. Van Cott. (2007) Hypercoagulation Testing in Ischemic Stroke. Archives of Pathology & Laboratory Medicine 131:6, pages 890-901.
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Hai Wei Huang, Ming Hui Guo, Rui Jin Lin, Ya Li Chen, Qin Luo, Ying Zhang & Ka Sing Wong. (2007) Hyperhomocysteinemia is a risk factor of middle cerebral artery stenosis. Journal of Neurology 254:3, pages 364-367.
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Nongnuch Sirachainan, Pornsri Tapanapruksakul, Anannit Visudtibhan, Ampaiwan Chuansumrit, Cheeraratana Cheeramakara, Kalayanee Atamasirikul, Sukanya Chotsuppakarn & Suvit Areekul. (2006) Homocysteine, MTHFR C677 T, Vitamin B12, and Folate Levels in Thai Children With Ischemic Stroke: A Case-control Study. Journal of Pediatric Hematology/Oncology 28:12, pages 803-808.
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R. Castro, I. Rivera, H. J. Blom, C. Jakobs & I. Tavares de Almeida. (2006) Homocysteine metabolism, hyperhomocysteinaemia and vascular disease: An overview. Journal of Inherited Metabolic Disease 29:1, pages 3-20.
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H.-K. Kuo, F. A. Sorond, J.-H. Chen, A. Hashmi, W. P. Milberg & L. A. Lipsitz. (2005) The Role of Homocysteine in Multisystem Age-Related Problems: A Systematic Review. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 60:9, pages 1190-1201.
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Anna B. Sobol, Edward Bald & Jerzy Loba. (2016) Fractions of Total Plasma Homocysteine in Patients with Ischemic Stroke Before the Age of 55 Years. Angiology 56:2, pages 201-209.
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Perminder Sachdev. (2004) Homocysteine, cerebrovascular disease and brain atrophy. Journal of the Neurological Sciences 226:1-2, pages 25-29.
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