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Research Article

Diagnostic value of the mean corpuscular volume in the detection of vitamin B12 deficiency

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Pages 9-18 | Published online: 08 Jul 2009

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Ülgen S. Fideli, Ann I. Scher, Cara Olsen & Elizabeth Hisle-Gorman. (2023) Assessing mean corpuscular volume as a screening tool for gestational vitamin B12 deficiency based on NHANES. International Journal for Vitamin and Nutrition Research.
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Gökçe CELEP & Sümeyye EVSİLE. (2023) VITAMIN B12 DEFICIENCY IN CHILDOOD: A SINGLE CENTRE EXPERIENCE. Sabuncuoglu Serefeddin Health Sciences 5:1, pages 34-43.
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Muhammad Asif, Saima Siddiqui, Shabnam Dildar, Rehana Ahmed & Tahir Shamsi. (2023) The catch in complete blood count when vitamin B12 deficiency is hiding behind microcytic anemia. The Egyptian Journal of Haematology 48:3, pages 210-214.
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Tesfaye Madebo, Mitra Bemanian, Jørn Henrik Vold, Ranadip Chowdhury, Christer Frode Aas, Karl Trygve Druckrey-Fiskaaen, Kjell Arne Johansson & Lars Thore Fadnes. (2022) Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics among People with Severe Substance Use Disorders: A Cohort Study from Western Norway. Nutrients 14:9, pages 1941.
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Amer Abu-Shanab, Malek Zihlif, Momen N. Rbeihat, Zakaria W. Shkoukani, Alia Khamis, Ula Isleem & Latefa A. Dardas. (2021) Vitamin B12 Deficiency Among the Healthy Jordanian Adult Population: Diagnostic Levels, Symptomology and Risk Factors. Endocrine, Metabolic & Immune Disorders - Drug Targets 21:6, pages 1107-1114.
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Jennifer Davila & Maria C. Velez-Yanguas. 2020. Hematology in the Adolescent Female. Hematology in the Adolescent Female 195 201 .
Sualeh Muslim Khan & Muhammad Akbar Agha. (2018) Mean cell volume of reticulocyte—A new parameter for diagnosing sub‐clinical cobalamin deficiency in blood donors. International Journal of Laboratory Hematology 41:1.
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Dominic J. Harrington. 2019. Laboratory Assessment of Vitamin Status. Laboratory Assessment of Vitamin Status 265 299 .
Antonia FH Smelt, Jacobijn Gussekloo, Lynette W Bermingham, Elizabeth Allen, Alan D Dangour, Simone JPM Eussen, Bernard Favrat, Lisette CPGM De Groot, Frans J Kok, Timothy Kwok, Arduino A Mangoni, George Ntaios, Ondine Van De Rest, Eric Seal, Paul Vaucher, Petra Verhoef, Theo Stijnen & Wendy PJ Den Elzen. (2018) The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis. European Journal of Clinical Nutrition 72:6, pages 785-795.
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Farhanah Yousaf, Bruce Spinowitz, Chaim Charytan & Marilyn Galler. (2017) Pernicious Anemia Associated Cobalamin Deficiency and Thrombotic Microangiopathy: Case Report and Review of the Literature. Case Reports in Medicine 2017, pages 1-8.
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Chit Wai Wong. 2017. Nutrition and Functional Foods for Healthy Aging. Nutrition and Functional Foods for Healthy Aging 159 166 .
D. Totoskovic, V. Dopsaj & J. Martinovic. (2016) Methylmalonic acid and neutrophil morphometric index in laboratory diagnosis of cobalamin deficiency without macrocytosis. International Journal of Laboratory Hematology 38:3, pages 265-272.
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A. F. Remacha, I. Wright, M. C. Fernández‐Jiménez, L. Toxqui, R. Blanco‐Rojo, G. Moreno & M. P. Vaquero. (2015) Vitamin B12 and folate levels increase during treatment of iron deficiency anaemia in young adult woman. International Journal of Laboratory Hematology 37:5, pages 641-648.
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C.W. Wong, C.Y. Ip, C.P. Leung, C.S. Leung, J.N. Cheng & C.Y. Siu. (2015) Vitamin B12 deficiency in the institutionalized elderly: A regional study. Experimental Gerontology 69, pages 221-225.
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Eric Earl, Renee Wong & Michael W. C. Payne. (2014) Low Vitamin B 12 in Patients on Admission to an Amputation Rehabilitation Unit . Nutrition in Clinical Practice 30:1, pages 122-127.
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G J Mearns, J Koziol-McLain, V Obolonkin & E C Rush. (2014) Preventing vitamin B12 deficiency in South Asian women of childbearing age: a randomised controlled trial comparing an oral vitamin B12 supplement with B12 dietary advice. European Journal of Clinical Nutrition 68:8, pages 870-875.
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Aída Gil Díaz, Alicia Conde Martel, Belén Alonso Ortíz & María Eugenia Arkuch Saade. (2014) Prevalencia de déficit de vitamina B12 en pacientes con anemia ferropénica remitidos para estudio a Medicina Interna. Medicina Clínica 142:1, pages 41-42.
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Angel F. Remacha, M. P. Sardà, C. Canals, J. M. Queraltò, E. Zapico, J. Remacha & C. Carrascosa. (2012) Combined cobalamin and iron deficiency anemia: a diagnostic approach using a model based on age and homocysteine assessment. Annals of Hematology 92:4, pages 527-531.
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C. RISCH, P. MEDINA, U. E. NYDEGGER, Z. BAHADOR, T. BRINKMANN, P. Von LANDENBERG, M. RISCH & L. RISCH. (2011) The relationship of leukocyte anisocytosis to holotranscobalamin, a marker of cobalamin deficiency. International Journal of Laboratory Hematology 34:2, pages 192-200.
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Rohit Jain, Menka Kapil & Gajendra Nath Gupta. (2012) M.C.V. should not be the only criteria to order vitamin B12 for anemia under evaluation. Open Journal of Gastroenterology 02:04, pages 187-190.
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Edward Valente, John M Scott, Per-Magne Ueland, Conal Cunningham, Miriam Casey & Anne M Molloy. (2011) Diagnostic Accuracy of Holotranscobalamin, Methylmalonic Acid, Serum Cobalamin, and Other Indicators of Tissue Vitamin B12 Status in the Elderly. Clinical Chemistry 57:6, pages 856-863.
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Wendy PJ den Elzen, Gerda M van der Weele, Jacobijn Gussekloo, Rudi GJ Westendorp & Willem JJ Assendelft. (2010) Subnormal vitamin B12 concentrations and anaemia in older people: a systematic review. BMC Geriatrics 10:1.
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Jack Metz. (2008) A High Prevalence of Biochemical Evidence of Vitamin B 12 or Folate Deficiency does not Translate into a Comparable Prevalence of Anemia . Food and Nutrition Bulletin 29:2_suppl1, pages S74-S85.
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Geraldine J. Cuskelly, Kathleen M. Mooney & Ian S. Young. (2007) Folate and vitamin B 12 : friendly or enemy nutrients for the elderly . Proceedings of the Nutrition Society 66:4, pages 548-558.
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Majid Moridani & Shana Ben-Poorat. (2006) Laboratory Investigation of Vitamin B 12 Deficiency . Laboratory Medicine 37:3, pages 166-174.
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T. Kwok, G. Cheng, J. Woo, W.K. Lai & C.P. Pang. (2002) Independent effect of vitamin B 12 deficiency on hematological status in older Chinese vegetarian women . American Journal of Hematology 70:3, pages 186-190.
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Elizabeth Cyran. (2002) Vitamin B12 Deficiency: Recognition and Management. Primary Care Case Reviews 5:2, pages 53-60.
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Chung Hin Chui, Fung Yi Lau, Raymond Wong, Oi Yan Soo, Chuk Kwan Lam, Pui Wai Lee, Ho Kei Leung, Chiu Kui So, Wai Chiu Tsoi, Nelson Tang, Wai Kei Lam & Gregory Cheng. (2001) Vitamin B12 deficiency—need for a new guideline. Nutrition 17:11-12, pages 917-920.
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