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Scandinavian Journal of Clinical and Laboratory Investigation Volume 61, 2001 - Issue 2
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Research Article

Trypsinogen-1, -2 and tumour-associated trypsin-inhibitor in bile and biliary tract tissues from patients with biliary tract diseases and pancreatic carcinomas

J. Hedström, C. Haglund, J. Leinonen, S. Nordling, U.-H. Stenman Department of Clinical Chemistry and Department of Otorhinolaryngology, University of Helsinki, Finland; Department of Surgery and Department of Pathology, University of Helsinki, Finland; Department of Clinical Chemistry, University of Helsinki, Finland; Department of Pathology, University of Helsinki, Finland
Pages 111-118 | Published online: 08 Jul 2009

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Ulf-Håkan Stenman. (2016) Biomarker development, from bench to bedside. Critical Reviews in Clinical Laboratory Sciences 53:2, pages 69-86.
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Annukka Paju & Ulf-Håkan Stenman. (2006) Biochemistry and Clinical Role of Trypsinogens and Pancreatic Secretory Trypsin Inhibitor. Critical Reviews in Clinical Laboratory Sciences 43:2, pages 103-142.
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Qiang Xu, Ziyang Yu, Qiteng Mei, Kejun Shi, Jiaofeng Shen, Guangyu Gao, Songtao Liu & Ming Li. (2024) Keratin 6A (KRT6A) promotes radioresistance, invasion, and metastasis in lung cancer via p53 signaling pathway. Aging.
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Haifeng Qin, Shushu Zhang, Linling Shen, Chenjian Mao, Guangyu Gao & Hui Wang. (2023) High expression of serine protease 2 (PRSS2) associated with invasion, metastasis, and proliferation in gastric cancer. Aging 15:7, pages 2473-2484.
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Hannu Koistinen, Sonja Boyd, Johanna Arola, Kalle Jokelainen, Riitta Koistinen, Anna Lempiäinen, Kristina Hotakainen, Ulf-Håkan Stenman & Martti Färkkilä. (2021) Biliary hCGβ Is a Potential Novel Marker for Prediction of Biliary Neoplasia in Primary Sclerosing Cholangitis Patients. Livers 1:4, pages 322-329.
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Robert S O'Neill & Alina Stoita. (2021) Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?. World Journal of Gastroenterology 27:26, pages 4045-4087.
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Kjetil SøreideMarcus RoalsøJan Rune Aunan. (2020) Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis. Journal of Pancreatic Cancer 6:1, pages 12-20.
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Hai Yan Ying, Chao Jie Gong, Yi Feng, Da Dao Jing & Lun Gen Lu. (2017) Serine protease inhibitor Kazal type 1 ( SPINK 1 ) downregulates E‐cadherin and induces EMT of hepatoma cells to promote hepatocellular carcinoma metastasis via the MEK/ERK signaling pathway . Journal of Digestive Diseases 18:6, pages 349-358.
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Kati Räsänen, Outi Itkonen, Hannu Koistinen & Ulf-Håkan Stenman. (2016) Emerging Roles of SPINK1 in Cancer. Clinical Chemistry 62:3, pages 449-457.
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Outi Itkonen & Ulf-Håkan Stenman. (2014) TATI as a biomarker. Clinica Chimica Acta 431, pages 260-269.
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Sari Räty, Juhani Sand, Johanna Laukkarinen, Kaija Vasama, Claudio Bassi, Roberto Salvia & Isto Nordback. (2013) Cyst fluid SPINK1 may help to differentiate benign and potentially malignant cystic pancreatic lesions. Pancreatology 13:5, pages 530-533.
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Aileen Marshall, Margus Lukk, Claudia Kutter, Susan Davies, Graeme Alexander & Duncan T. Odom. (2013) Global Gene Expression Profiling Reveals SPINK1 as a Potential Hepatocellular Carcinoma Marker. PLoS ONE 8:3, pages e59459.
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Alexander Gaber, Björn Nodin, Kristina Hotakainen, Elise Nilsson, Ulf-Håkan Stenman, Anders Bjartell, Helgi Birgisson & Karin Jirström. (2010) Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients. BMC Cancer 10:1.
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Sakhawat H. Rahman, Krishna V. Menon, John H. M. Holmfield, Michael J. McMahon & J Pierre Guillou. (2007) Serum Macrophage Migration Inhibitory Factor Is an Early Marker of Pancreatic Necrosis in Acute Pancreatitis. Annals of Surgery 245:2, pages 282-289.
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Akihiko Tonouchi, Masayuki Ohtsuka, Hiroshi Ito, Fumio Kimura, Hiroaki Shimizu, Masaki Kato, Yoshinori Nimura, Katsuro Iwase, Takaki Hiwasa, Naohiko Seki, Masaki Takiguchi & Masaru Miyazaki. (2006) Relationship Between Pancreatic Secretory Trypsin Inhibitor and Early Recurrence of Intrahepatic Cholangiocarcinoma Following Surgical Resection. The American Journal of Gastroenterology 101:7, pages 1601-1610.
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Sari Räty, Juhani Sand, Henrik Alfthan, Caj Haglund & Isto Nordback. (2004) Cyst fluid tumor-associated trypsin inhibitor may be helpful in the differentiation of cystic pancreatic lesions. Journal of Gastrointestinal Surgery 8:5, pages 569-574.
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Ulf-Håkan Stenman. (2002) Tumor-associated Trypsin Inhibitor. Clinical Chemistry 48:8, pages 1206-1209.
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