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Review

Experimental pain in gastroenterology: a reappraisal of human studies

, &
Pages 1115-1130 | Received 13 Feb 2003, Accepted 26 May 2003, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Tine Maria Hansen, Esben Bolvig Mark, Søren Schou Olesen, Mikkel Gram, Jens Brøndum Frøkjær & Asbjørn Mohr Drewes. (2017) Characterization of cortical source generators based on electroencephalography during tonic pain. Journal of Pain Research 10, pages 1401-1409.
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Adam D Farmer, Christina Brock, Jens Brøndum Frøkjaer, Hans Gregersen, Sheeba Khan, Dina Lelic, Christian Lottrup & Asbjørn Mohr Drewes. (2016) Understanding the sensory irregularities of esophageal disease. Expert Review of Gastroenterology & Hepatology 10:8, pages 907-914.
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Lars Arendt-Nielsen & Hans Christian Hoeck. (2011) Optimizing the early phase development of new analgesics by human pain biomarkers. Expert Review of Neurotherapeutics 11:11, pages 1631-1651.
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Anne Lund Krarup, Gerda Elisabeth Villadsen, Else Mejlgaard, Søren Schou Olesen, Asbjørn Mohr Drewes & Peter Funch-Jensen. (2010) Acid hypersensitivity in patients with eosinophilic oesophagitis. Scandinavian Journal of Gastroenterology 45:3, pages 273-281.
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Hariprasad Reddy, Camilla Staahl, Lars Arendt-Nielsen, Hans Gregersen, Asbjørn Mohr Drewes & Peter Funch-Jensen. (2007) Sensory and biomechanical properties of the esophagus in non-erosive reflux disease. Scandinavian Journal of Gastroenterology 42:4, pages 432-440.
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Asbjørn Mohr Drewes, Jan Pedersen, Hariprasad Reddy, Klaus Rasmussen, Peter Funch-Jensen, Lars Arendt-Nielsen & Hans Gregersen. (2006) Central sensitization in patients with non-cardiac chest pain: A clinical experimental study. Scandinavian Journal of Gastroenterology 41:6, pages 640-649.
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p. g. dinning, j. w. arkwright, h. gregersen, g. o'grady & s. m. scott. (2010) Technical advances in monitoring human motility patterns. Neurogastroenterology & Motility 22:4, pages 366-380.
Crossref
Christina Brock, Trine Andresen, Jens Brøndum Frøkjær, Jeremy Gale, Anne Estrup Olesen, Lars Arendt‐Nielsen & Asbjørn Mohr Drewes. (2012) Central pain mechanisms following combined acid and capsaicin perfusion of the human oesophagus. European Journal of Pain 14:3, pages 273-281.
Crossref
Dag Arne Lihaug Hoff, Hans Gregersen, Svein Odegaard, Donghua Liao & Jan Gunnar Hatlebakk. (2009) Mechanosensation and Mucosal Blood Perfusion in the Esophagus of Healthy Volunteers Studied with a Multimodal Device Incorporating Laser Doppler Flowmetry and Endosonography. Digestive Diseases and Sciences 55:2, pages 312-320.
Crossref
S. S. Olesen, A. E. Olesen, F. Gravesen, J. L. Poulsen, P. Funch‐jensen, H. Gregersen & A. M. Drewes. (2009) An endoscopic method for thermal and chemical stimulation of the human oesophagus. Neurogastroenterology & Motility 21:12, pages 1250.
Crossref
Camilla Staahl, Anne Estrup Olesen, Trine Andresen, Lars Arendt‐Nielsen & Asbjørn Mohr Drewes. (2009) Assessing efficacy of non‐opioid analgesics in experimental pain models in healthy volunteers: an updated review. British Journal of Clinical Pharmacology 68:3, pages 322-341.
Crossref
Anne Estrup Olesen, Camilla Staahl, Christina Brock, Lars Arendt‐Nielsen & Asbjørn Mohr Drewes. (2009) Evoked Human Oesophageal Hyperalgesia: A Potential Tool for Analgesic Evaluation?. Basic & Clinical Pharmacology & Toxicology 105:2, pages 126-136.
Crossref
Camilla Staahl, Anne Estrup Olesen, Trine Andresen, Lars Arendt‐Nielsen & Asbjørn Mohr Drewes. (2009) Assessing analgesic actions of opioids by experimental pain models in healthy volunteers – an updated review. British Journal of Clinical Pharmacology 68:2, pages 149-168.
Crossref
Anne Estrup Olesen, Trine Andresen, Lona Louring Christrup & Richard N Upton. (2009) Translational pain research: Evaluating analgesic effect in experimental visceral pain models. World Journal of Gastroenterology 15:2, pages 177.
Crossref
Dong-Hua Liao, Jing-Bo Zhao & Hans Gregersen. (2009) Gastrointestinal tract modelling in health and disease. World Journal of Gastroenterology 15:2, pages 169.
Crossref
Christina Brock, Lars Arendt-Nielsen, Oliver Wilder-Smith & Asbjørn Mohr Drewes. (2009) Sensory testing of the human gastrointestinal tract. World Journal of Gastroenterology 15:2, pages 151.
Crossref
Donghua Liao, Dina Lelic, Feng Gao, Asbjørn Mohr Drewes & Hans Gregersen. (2008) Biomechanical functional and sensory modelling of the gastrointestinal tract. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 366:1879, pages 3281-3299.
Crossref
C. Brock, T. D. Nissen, F. H. Gravesen, J. B. Frøkjær, H. Omar, J. Gale, H. Gregersen, O. Svendsen & A. M. Drewes. (2008) Multimodal sensory testing of the rectum and rectosigmoid: development and reproducibility of a new method. Neurogastroenterology & Motility 20:8, pages 908-918.
Crossref
Martina Führer & Johann Hammer. (2008) Duodenal chemosensitivity and mechanosensitivity in humans during acid and ethanol perfusion. European Journal of Gastroenterology & Hepatology 20:6, pages 537-544.
Crossref
Camilla Staahl, Richard Upton, David J. R. Foster, Lona Louring Christrup, Kim Kristensen, Steen Honoré Hansen, Lars Arendt‐Nielsen & Asbjørn Mohr Drewes. (2013) Pharmacokinetic‐Pharmacodynamic Modeling of Morphine and Oxycodone Concentrations and Analgesic Effect in a Multimodal Experimental Pain Model. The Journal of Clinical Pharmacology 48:5, pages 619-631.
Crossref
D. Liao, J. B. Frøkjær, C. Brock, S. D. Andersen, A. M. Drewes & H. Gregersen. (2007) Oesophageal heat transfer properties indication of segmental blood flow changes during distension. Neurogastroenterology & Motility 20:4, pages 298-303.
Crossref
Michelle D. Smith, Anne Russell & Paul W. Hodges. (2008) How Common Is Back Pain in Women With Gastrointestinal Problems?. The Clinical Journal of Pain 24:3, pages 199-203.
Crossref
Asbjørn M Drewes, Maciej Gratkowski, Saber AK Sami, Georg Dimcevski, Peter Funch-Jensen & Lars Arendt-Nielsen. (2008) Is the pain in chronic pancreatitis of neuropathic origin? Support from EEG studies during experimental pain. World Journal of Gastroenterology 14:25, pages 4020.
Crossref
Willem Brinkert, Georg Dimcevski, Lars Arendt-Nielsen, Asbjørn M. Drewes & Oliver H.G. Wilder-Smith. (2007) Dysmenorrhoea is associated with hypersensitivity in the sigmoid colon and rectum. Pain 132:Supplement 1, pages S46-S51.
Crossref
Anne Estrup Olesen, Camilla Staahl, Zahid Ali, Asbjørn Mohr Drewes & Lars Arendt‐Nielsen. (2007) Effects of Paracetamol Combined with Dextromethorphan in Human Experimental Muscle and Skin Pain. Basic & Clinical Pharmacology & Toxicology 101:3, pages 172-176.
Crossref
Georg Dimcevski, Camilla Staahl, Søren Due Andersen, Niels Thorsgaard, Peter Funch-Jensen, Lars Arendt-Nielsen & Asbjørn Mohr Drewes. (2007) Assessment of Experimental Pain From Skin, Muscle, and Esophagus in Patients With Chronic Pancreatitis. Pancreas 35:1, pages 22-29.
Crossref
Joanna C. Murrell, Sheryl L. Mitchinson, Alastair C. Johnstone, Craig B. Johnson & Geoffrey R.G. Barnes. (2007) Is it possible to generate cerebral evoked potentials with a mechanical stimulus from the duodenum in rats?. Journal of Neuroscience Methods 162:1-2, pages 215-221.
Crossref
J. B. Frøkjær, D. Liao, E. Steffensen, G. Dimcevski, A. Bergmann, A. M. Drewes & H. Gregersen. (2007) Geometric and mechanosensory properties of the sigmoid colon evaluated with magnetic resonance imaging. Neurogastroenterology & Motility 19:4, pages 253-262.
Crossref
Georg Dimcevski, Saber A.K. Sami, Peter Funch–Jensen, Domenica Le Pera, Massimiliano Valeriani, Lars Arendt–Nielsen & Asbjørn M. Drewes. (2007) Pain in Chronic Pancreatitis: The Role of Reorganization in the Central Nervous System. Gastroenterology 132:4, pages 1546-1556.
Crossref
H. Gregersen, M. A. Kwiatek, W. Schwizer & R. Tutuian. (2007) Contribution of sensitivity, volume and tone to visceral perception in the upper gastrointestinal tract in man: emphasis on testing. Neurogastroenterology & Motility 19:s1, pages 47-61.
Crossref
T Ness. 2006. Chronic Abdominal and Visceral Pain. Chronic Abdominal and Visceral Pain 1 10 .
Asbjørn Mohr Drewes, Georg Dimcevski, Saber A. K. Sami, Peter Funch-Jensen, Khiem Dinh Huynh, Domenica Le Pera, Lars Arendt-Nielsen & Massimiliano Valeriani. (2006) The “human visceral homunculus” to pain evoked in the oesophagus, stomach, duodenum and sigmoid colon. Experimental Brain Research 174:3, pages 443-452.
Crossref
Jens Brøndum Frøkjær, Søren Due Andersen, Asbjørn Mohr Drewes & Hans Gregersen. (2006) Ultrasound-Determined Geometric and Biomechanical Properties of the Human Duodenum. Digestive Diseases and Sciences 51:9, pages 1662-1669.
Crossref
Georg Dimcevski, Klaus P. Schipper, Ulrik Tage-Jensen, Peter Funch-Jensen, Anne L. Krarup, Egon Toft, Niels Thorsgaard, Lars Arendt-Nielsen & Asbj??rn M. Drewes. (2006) Hypoalgesia to experimental visceral and somatic stimulation in painful chronic pancreatitis. European Journal of Gastroenterology & Hepatology 18:7, pages 755-764.
Crossref
Camilla Staahl, Lona Louring Christrup, Sren Due Andersen, Lars Arendt-Nielsen & Asbjrn Mohr Drewes. (2006) A comparative study of oxycodone and morphine in a multi-modal, tissue-differentiated experimental pain model. Pain 123:1, pages 28-36.
Crossref
. (2006) Laser Literature Watch. Photomedicine and Laser Surgery 24:3, pages 424-453.
Crossref
H. Gregersen, T. Hausken, J. Yang, S. Ødegaard & O. H. Gilja. (2006) Mechanosensory properties in the human gastric antrum evaluated using B-mode ultrasonography during volume-controlled antral distension. American Journal of Physiology-Gastrointestinal and Liver Physiology 290:5, pages G876-G882.
Crossref
Asbjrn Mohr Drewes, Jens Brndum Frkjær, Ejnar Larsen, Hariprasad Reddy, Lars Arendt-Nielsen & Hans Gregersen. (2006) Pain and mechanical properties of the rectum in patients with active ulcerative colitis. Inflammatory Bowel Diseases 12:4, pages 294-303.
Crossref
Camilla Staahl, Hariprasad Reddy, Søren Due Andersen, Lars Arendt‐Nielsen & Asbjørn Mohr Drewes. (2006) Multi‐Modal and Tissue‐Differentiated Experimental Pain Assessment: Reproducibility of a New Concept for Assessment of Analgesics. Basic & Clinical Pharmacology & Toxicology 98:2, pages 201-211.
Crossref
J. B. Frøkjær, S. D. Andersen, S. Lundbye‐christensen, P. Funch‐jensen, A. M. Drewes & H. Gregersen. (2006) Sensation and distribution of stress and deformation in the human oesophagus. Neurogastroenterology & Motility 18:2, pages 104-114.
Crossref
Ejnar Larsen. (2006) Ultrasonographic study of mechanosensory properties in human esophagus during mechanical distension. World Journal of Gastroenterology 12:28, pages 4517.
Crossref
Jing-Bo Zhao. (2006) Upper gastrointestinal sensory-motor dysfunction in diabetes mellitus. World Journal of Gastroenterology 12:18, pages 2846.
Crossref
Asbjørn Mohr Drewes. (2006) Experimental human pain models in gastro-esophageal reflux disease and unexplained chest pain. World Journal of Gastroenterology 12:18, pages 2806.
Crossref
Asbjørn Mohr Drewes. (2006) Multimodal pain stimulation of the gastrointestinal tract. World Journal of Gastroenterology 12:16, pages 2477.
Crossref
S.A.K. Sami, P. Rössel, G. Dimcevski, K. Dremstrup Nielsen, P. Funch-Jensen, M. Valeriani, L. Arendt-Nielsen & A.M. Drewes. (2006) Cortical changes to experimental sensitization of the human esophagus. Neuroscience 140:1, pages 269-279.
Crossref
Jens Brøndum Frøkjær, Søren Due Andersen, Jeremy Gale, Lars Arendt-Nielsen, Hans Gregersen & Asbjørn Mohr Drewes. (2005) An experimental study of viscero-visceral hyperalgesia using an ultrasound-based multimodal sensory testing approach. Pain 119:1-3, pages 191-200.
Crossref
Hariprasad Reddy, Lars Arendt-Nielsen, Camilla Staahl, Jan Pedersen, Peter Funch-Jensen, Hans Gregersen & Asbjørn Mohr Drewes. (2005) Gender Differences in Pain and Biomechanical Responses After Acid Sensitization of the Human Esophagus. Digestive Diseases and Sciences 50:11, pages 2050-2058.
Crossref
Asbjorn Mohr Drewes. (2005) Sensory-motor responses to mechanical stimulation of the esophagus after sensitization with acid. World Journal of Gastroenterology 11:28, pages 4367.
Crossref
Lars Arendt‐Nielsen, Priti Bajaj & Asbjørn Mohr Drewes. (2012) Visceral pain: gender differences in response to experimental and clinical pain. European Journal of Pain 8:5, pages 465-472.
Crossref
Camilla Staahl & Asbjørn Mohr Drewes. (2004) Experimental Human Pain Models: A Review of Standardised Methods for Preclinical Testing of Analgesics. Basic & Clinical Pharmacology & Toxicology 95:3, pages 97-111.
Crossref
Jan Pedersen, Hariprasad Reddy, Peter Funch-Jensen, Lars Arendt-Nielsen, Hans Gregersen & Asbjørn Mohr Drewes. (2004) Cold and heat pain assessment of the human oesophagus after experimental sensitisation with acid. Pain 110:1, pages 393-399.
Crossref
Xiaomin Huang, Jiali Chen, Xianglong Wang, Xuefei Zhang, Junqin Ma, Sishi Liu, Xinli Liu, Qiling Ou, Wenwei Tan & Wen Wu. (2022) The Excessive Generalization of Fear Affected by Perceptual Bias in Experimental Pain Individuals: Evidence from an Event-Related Potential Study. SSRN Electronic Journal.
Crossref

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