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Scandinavian Journal of Gastroenterology Volume 39, 2004 - Issue 12
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Research Article

Ghrelin enhances gastric motility through direct stimulation of intrinsic neural pathways and capsaicin-sensitive afferent neurones in rats

H. Fukuda Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
Y. Mizuta Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
H. Isomoto Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
F. Takeshima Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
K. Ohnita Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
K. Ohba Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
K. Omagari Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
,
K. Taniyama Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
&
S. Kohno Second Depts. of Internal Medicine and Pharmacology Nagasaki University School of Medicine Nagasaki Japan
 show all
Pages 1209-1214 | Published online: 08 Jul 2009

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Hsien-Hao Huang, Liang-Yu Chen, Ming-Luen Doong, Shi-Chuan Chang & Chih-Yen Chen. (2017) α-melanocyte stimulating hormone modulates the central acyl ghrelin-induced stimulation of feeding, gastrointestinal motility, and colonic secretion. Drug Design, Development and Therapy 11, pages 2377-2386.
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Mark Malamood, Henry Parkman & Ron Schey. (2015) Current advances in treatment of gastroparesis. Expert Opinion on Pharmacotherapy 16:13, pages 1997-2008.
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Yan Wang, Lei Dong, Yan Cheng & Ping Zhao. (2007) Effects of ghrelin on feeding regulation and interdigestive migrating complex in rats. Scandinavian Journal of Gastroenterology 42:4, pages 447-453.
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Articles from other publishers (88)

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Mario Perelló, María P. Cornejo, Pablo N. De Francesco, Gimena Fernandez, Laurent Gautron & Lesly S. Valdivia. (2022) The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond. IBRO Neuroscience Reports 12, pages 228-239.
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Sara L. Deschaine & Lorenzo Leggio. (2022) From “Hunger Hormone” to “It’s Complicated”: Ghrelin Beyond Feeding Control. Physiology 37:1, pages 5-15.
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Joyce James, Stuart Mair, Walter Doll, Erik Sandefer, David Wurtman, Alan Maurer, Adam M Deane & M. Scott Harris. (2020) The effects of ulimorelin, a ghrelin agonist, on liquid gastric emptying and colonic transit in humans. Neurogastroenterology & Motility 32:3.
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Hsien-Hao Huang & Chih-Yen Chen. (2019) Alpha-melanocyte stimulating hormone in ghrelin-elicited feeding and gut motility. Journal of the Chinese Medical Association 82:2, pages 87-91.
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Ehsan N. Mohammadi, Claudio Pietra, Claudio Giuliano, Li Fugang & Beverley Greenwood-Van Meerveld. (2019) A Comparison of the Central versus Peripheral Gastrointestinal Prokinetic Activity of Two Novel Ghrelin Mimetics. Journal of Pharmacology and Experimental Therapeutics 368:1, pages 116-124.
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Gai Mei Du, Bi Ping Luo, Zhi Hua Hu, Jie Ge Wu, Wen Mei Yan, Zheng Qiang Han, Yu Hong Zhang & Mao Jun Liu. (2018) The effect of ghrelin O-acyltransferase inhibitor on gastric H+–K+-ATPase activity and GOAT/ghrelin system in gastric mucosal cells in vitro. General and Comparative Endocrinology 267, pages 167-171.
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E. M. Besecker, A. R. White & G. M. Holmes. (2017) Diminished gastric prokinetic response to ghrelin in a rat model of spinal cord injury. Neurogastroenterology & Motility 30:4.
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Ken Howick, Brendan Griffin, John Cryan & Harriët Schellekens. (2017) From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation. International Journal of Molecular Sciences 18:2, pages 273.
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Takio Kitazawa, Hiroki Teraoka & Hiroyuki Kaiya. (2017) The chicken is an interesting animal for study of the functional role of ghrelin in the gastrointestinal tract. Endocrine Journal 64:Suppl., pages S5-S9.
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Gintautas Grabauskas & Chung Owyang. (2017) Plasticity of vagal afferent signaling in the gut. Medicina 53:2, pages 73-84.
Crossref
S. A. Mard, I. Ahmadi, A. Ahangarpour, M. K. Gharib‐Naseri & M. Badavi. (2016) Delayed gastric emptying in diabetic rats caused by decreased expression of cystathionine gamma lyase and H 2 S synthesis: in vitro and in vivo studies . Neurogastroenterology & Motility 28:11, pages 1677-1689.
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Takio Kitazawa, Misato Shimazaki, Ayumi Kikuta, Noriko Yaosaka, Hiroki Teraoka & Hiroyuki Kaiya. (2016) Effects of ghrelin and motilin on smooth muscle contractility of the isolated gastrointestinal tract from the bullfrog and Japanese fire belly newt. General and Comparative Endocrinology 232, pages 51-59.
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Gai M. Du, Jie G. Wu, Bi P. Luo, Zhi H. Hu, Liu A. Li & Mao J. Liu. (2016) RNAi-mediated Ghrelin affects gastric H+–K+-ATPase activity and expression of GOAT–Ghrelin system in vitro. General and Comparative Endocrinology 228, pages 48-52.
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Ziru Li, Michael Mulholland & Weizhen Zhang. (2016) Ghrelin O-acyltransferase (GOAT) and energy metabolism. Science China Life Sciences 59:3, pages 281-291.
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Emanuele Sinagra, Giancarlo Pompei, Giovanni Tomasello, Francesco Cappello, Gaetano Cristian Morreale, Georgios Amvrosiadis, Francesca Rossi, Attilio Ignazio Lo Monte, Aroldo Gabriele Rizzo & Dario Raimondo. (2016) Inflammation in irritable bowel syndrome: Myth or new treatment target?. World Journal of Gastroenterology 22:7, pages 2242-2255.
Crossref
Magdy El-Salhy & Doris Gundersen. (2015) Diet in irritable bowel syndrome. Nutrition Journal 14:1.
Crossref
Yan Wang, Fenrong Chen, Haitao Shi, Jiong Jiang, Hong Li, Bin Qin & Yong Li. (2015) Extrinsic ghrelin in the paraventricular nucleus increases small intestinal motility in rats by activating central growth hormone secretagogue and enteric cholinergic receptors. Peptides 74, pages 43-49.
Crossref
Soad Shaker Ali, Enas Ahmed Hamed, Nasra Naeim Ayuob, Ahmed Shaker Ali & Mansour Ibrahem Suliman. (2015) Effects of different routes of nicotine administration on gastric morphology and hormonal secretion in rats. Experimental Physiology 100:8, pages 881-895.
Crossref
Bitoku Takahashi, Hideaki Funami, Takehiko Iwaki, Hiroshi Maruoka, Asako Nagahira, Makoto Koyama, Yoshiyuki Kamiide, Tsuyoshi Matsuo, Tsuyoshi Muto & Hirokazu Annoura. (2015) 2-Aminoalkyl nicotinamide derivatives as pure inverse agonists of the ghrelin receptor. Bioorganic & Medicinal Chemistry Letters 25:13, pages 2707-2712.
Crossref
T Mazzawi, T Hausken, D Gundersen & M El-Salhy. (2014) Effect of dietary management on the gastric endocrine cells in patients with irritable bowel syndrome. European Journal of Clinical Nutrition 69:4, pages 519-524.
Crossref
Takio Kitazawa, Takeo Hiraga, Hiroki Teraoka, Noriko Yaosaka & Hiroyuki Kaiya. (2015) Correlation of ghrelin concentration and ghrelin, ghrelin-O-acetyltransferase (GOAT) and growth hormone secretagogue receptor 1a mRNAs expression in the proventriculus and brain of the growing chicken. Peptides 63, pages 134-142.
Crossref
J. Broad, A. Góralczyk, K. Mannur, G. E. Dukes & G. J. Sanger. (2014) Drugs acting at 5‐ HT 4 , D 2 , motilin, and ghrelin receptors differ markedly in how they affect neuromuscular functions in human isolated stomach . Neurogastroenterology & Motility 26:6, pages 851-861.
Crossref
G. J. Sanger. (2014) Ghrelin and motilin receptor agonists: time to introduce bias into drug design. Neurogastroenterology & Motility 26:2, pages 149-155.
Crossref
Magdy El-Salhy. (2014) Endocrine cells in the oxyntic mucosa of the stomach in patients with irritable bowel syndrome. World Journal of Gastrointestinal Endoscopy 6:5, pages 176.
Crossref
Hiroyuki Ariyasu, Hiroshi Iwakura, Naoichiro Yukawa, Toshinori Murayama, Masayuki Yokode, Harue Tada, Kenichi Yoshimura, Satoshi Teramukai, Tatsuya Ito, Akira Shimizu, Atsushi Yonezawa, Kenji Kangawa, Tsuneyo Mimori & Takashi Akamizu. (2014) Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis. Endocrine Journal 61:7, pages 735-742.
Crossref
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Crossref
Magdy El-Salhy, Doris Gundersen, Jan Gunnar Hatlebakk & Trygve Hausken. 2014. Nutrition in the Prevention and Treatment of Abdominal Obesity. Nutrition in the Prevention and Treatment of Abdominal Obesity 5 16 .
B. Avau, F. Carbone, J. Tack & I. Depoortere. (2013) Ghrelin signaling in the gut, its physiological properties, and therapeutic potential. Neurogastroenterology & Motility 25:9, pages 720-732.
Crossref
B. Avau, B. De Smet, T. Thijs, A. Geuzens, J. Tack, P. Vanden Berghe & I. Depoortere. (2013) Ghrelin is involved in the paracrine communication between neurons and glial cells. Neurogastroenterology & Motility 25:9.
Crossref
G.M. Du, M.J. Liu, N. Parvizi & R.Q. Zhao. (2013) Ectopic expression of ghrelin affects gastric H+–K+-ATPase activity and expression of GHR/IGF-1 system in weaned mice. Regulatory Peptides 186, pages 12-17.
Crossref
Takio Kitazawa, Akiko Yoshida, Takuya Tamano, Hiroki Teraoka & Hiroyuki Kaiya. (2013) Age-dependent reduction of ghrelin- and motilin-induced contractile activity in the chicken gastrointestinal tract. Peptides 43, pages 88-95.
Crossref
Anupom Mondal, Sayaka Aizawa, Ichiro Sakata, Chayon Goswami, Sen-ichi Oda & Takafumi Sakai. (2013) Mechanism of Ghrelin-Induced Gastric Contractions in Suncus murinus (House Musk Shrew): Involvement of Intrinsic Primary Afferent Neurons. PLoS ONE 8:4, pages e60365.
Crossref
N. Ejskjaer, J. M. Wo, T. Esfandyari, M. Mazen Jamal, G. Dimcevski, L. Tarnow, R. A. Malik, P. M. Hellström, E. Mondou, J. Quinn, F. Rousseau & R. W. McCallum. (2012) A phase 2a, randomized, double‐blind 28‐day study of TZP‐102 a ghrelin receptor agonist for diabetic gastroparesis. Neurogastroenterology & Motility 25:2.
Crossref
Christine Delporte. (2013) Structure and Physiological Actions of Ghrelin. Scientifica 2013, pages 1-25.
Crossref
Hiroyuki Kaiya, Kenji Kangawa & Mikiya Miyazato. (2013) What is the general action of ghrelin for vertebrates? – Comparisons of ghrelin’s effects across vertebrates. General and Comparative Endocrinology 181, pages 187-191.
Crossref
Lisa K. Chopin, Inge Seim, Carina M. Walpole & Adrian C. Herington. (2012) The Ghrelin Axis—Does It Have an Appetite for Cancer Progression?. Endocrine Reviews 33:6, pages 849-891.
Crossref
Magdy El-Salhy. (2012) Irritable bowel syndrome: Diagnosis and pathogenesis. World Journal of Gastroenterology 18:37, pages 5151-5163.
Crossref
Paul J. Wellman, P. Shane Clifford, Juan A. Rodriguez, Samuel Hughes, Carla Di Francesco, Sergio Melotto, Michela Tessari, Mauro Corsi, Angelo Bifone & Alessandro Gozzi. (2011) Brain reinforcement system function is ghrelin dependent: studies in the rat using pharmacological fMRI and intracranial self‐stimulation. Addiction Biology 17:5, pages 908-919.
Crossref
Takio Kitazawa, Kentaro Itoh, Noriko Yaosaka, Keisuke Maruyama, Kouhei Matsuda, Hiroki Teraoka & Hiroyuki Kaiya. (2012) Ghrelin does not affect gastrointestinal contractility in rainbow trout and goldfish in vitro. General and Comparative Endocrinology 178:3, pages 539-545.
Crossref
Miwa NahataShuichi Muto, Nobuhiko Oridate, Shunsuke Ohnishi, Koji NakagawaChiharu SadakaneYayoi SaegusaTomohisa HattoriMasahiro AsakaHiroshi Takeda. (2012) Impaired ghrelin signaling is associated with gastrointestinal dysmotility in rats with gastroesophageal reflux disease. American Journal of Physiology-Gastrointestinal and Liver Physiology 303:1, pages G42-G53.
Crossref
Sara Janssen, Jorien Laermans, Hiroshi Iwakura, Jan Tack & Inge Depoortere. (2012) Sensing of Fatty Acids for Octanoylation of Ghrelin Involves a Gustatory G-Protein. PLoS ONE 7:6, pages e40168.
Crossref
L. Wang, N. P. Murphy, A. Stengel, M. Goebel‐Stengel, D. H. St Pierre, N. T. Maidment & Y. Taché. (2012) Ghrelin prevents levodopa‐induced inhibition of gastric emptying and increases circulating levodopa in fasted rats. Neurogastroenterology & Motility 24:5.
Crossref
Hajime Ariga, Kenji Imai, Kirk Ludwig & Toku Takahashi. (2012) Gastric emptying, plasma ghrelin and autonomic nerve activity in diabetic rats. Neuroscience Letters 514:1, pages 77-81.
Crossref
Takio Kitazawa, Tatsuro Nakamura, Atsuki Saeki, Hiroki Teraoka, Takeo Hiraga & Hiroyuki Kaiya. (2011) Molecular identification of ghrelin receptor (GHS-R1a) and its functional role in the gastrointestinal tract of the guinea-pig. Peptides 32:9, pages 1876-1886.
Crossref
J. M. Wo, N. Ejskjaer, P. M. Hellström, R. A. Malik, J. C. Pezzullo, L. Shaughnessy, P. Charlton, G. Kosutic & R. W. McCallum. (2011) Randomised clinical trial: ghrelin agonist TZP-101 relieves gastroparesis associated with severe nausea and vomiting - randomised clinical study subset data. Alimentary Pharmacology & Therapeutics 33:6, pages 679-688.
Crossref
N. Ejskjaer, G. Dimcevski, J. Wo, P. M. Hellström, L. C. Gormsen, I. Sarosiek, E. Søfteland, T. Nowak, J. C. Pezzullo, L. Shaughnessy, G. Kosutic & R. Mccallum. (2010) Safety and efficacy of ghrelin agonist TZP-101 in relieving symptoms in patients with diabetic gastroparesis: a randomized, placebo-controlled study. Neurogastroenterology & Motility 22:10, pages 1069-e281.
Crossref
Hanaa S. Sallam, Hermes M. Oliveira, Suhuan Liu & Jiande D. Z. Chen. (2010) Mechanisms of burn-induced impairment in gastric slow waves and emptying in rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 299:1, pages R298-R305.
Crossref
Ignacio A Gómez de Segura, María Teresa Vallejo-Cremades, Jesús Lomas, Miriam F Sánchez, María Isabel Caballero, Carlota Largo & Enrique De Miguel. (2010) Exogenous ghrelin regulates proliferation and apoptosis in the hypotrophic gut mucosa of the rat. Experimental Biology and Medicine 235:4, pages 463-469.
Crossref
t. nakamura, t. onaga & t. kitazawa. (2010) Ghrelin stimulates gastric motility of the guinea pig through activation of a capsaicin-sensitive neural pathway: in vivo and in vitro functional studies . Neurogastroenterology & Motility 22:4, pages 446-e107.
Crossref
Yong Wang & Jingang Liu. (2009) Combination of Bypassing Stomach and Vagus Dissection in High-Fat Diet-Induced Obese Rats—A Long-Term Investigation. Obesity Surgery 20:3, pages 375-379.
Crossref
Hanaa S. Sallam & Jiande D. Z. Chen. (2010) The Prokinetic Face of Ghrelin. International Journal of Peptides 2010, pages 1-11.
Crossref
T.R. Castañeda, J. Tong, R. Datta, M. Culler & M.H. Tschöp. (2010) Ghrelin in the regulation of body weight and metabolism. Frontiers in Neuroendocrinology 31:1, pages 44-60.
Crossref
Chih-Yen Chen, Akihiro Asakawa, Mineko Fujimiya, Shou-Dong Lee & Akio Inui. (2009) Ghrelin Gene Products and the Regulation of Food Intake and Gut Motility. Pharmacological Reviews 61:4, pages 430-481.
Crossref
Betty De Smet, Anna Mitselos & Inge Depoortere. (2009) Motilin and ghrelin as prokinetic drug targets. Pharmacology & Therapeutics 123:2, pages 207-223.
Crossref
Soratree Charoenthongtrakul, Derek Giuliana, Kenneth A. Longo, Elizabeth K. Govek, Anna Nolan, Samantha Gagne, Kristen Morgan, Jeffrey Hixon, Neil Flynn, Brian J. Murphy, Andres S. Hernández, Jun Li, Joseph A. Tino, David A. Gordon, Peter S. DiStefano & Brad J. Geddes. (2009) Enhanced Gastrointestinal Motility with Orally Active Ghrelin Receptor Agonists. Journal of Pharmacology and Experimental Therapeutics 329:3, pages 1178-1186.
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N. EJSKJAER, E. T. VESTERGAARD, P. M. HELLSTRÖM, L. C. GORMSEN, S. MADSBAD, J. L. MADSEN, T. A. JENSEN, J. C. PEZZULLO, J. S. CHRISTIANSEN, L. SHAUGHNESSY & G. KOSUTIC. (2009) Ghrelin receptor agonist (TZP‐101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis. Alimentary Pharmacology & Therapeutics 29:11, pages 1179-1187.
Crossref
Yogendra B. Shrestha, Kathie Wickwire & Silvia Q. Giraudo. (2009) Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats. Peptides 30:6, pages 1187-1191.
Crossref
Astrid J. Smeets & Margriet S. Westerterp-Plantenga. (2009) The acute effects of a lunch containing capsaicin on energy and substrate utilisation, hormones, and satiety. European Journal of Nutrition 48:4, pages 229-234.
Crossref
William Wargin, Helmut Thomas, Lilian Clohs, Carl St-Louis, Niels Ejskjaer, Maria Gutierrez, Laura Shaughnessy & Gordana Kosutic. (2009) Contribution of Protein Binding to the Pharmacokinetics of the Ghrelin Receptor Agonist TZP-101 in Healthy Volunteers and Adults with Symptomatic Gastroparesis. Clinical Drug Investigation 29:6, pages 409-418.
Crossref
Yong Wang & Jingang Liu. (2008) Plasma Ghrelin Modulation in Gastric Band Operation and Sleeve Gastrectomy. Obesity Surgery 19:3, pages 357-362.
Crossref
Hiroshi Taniguchi, Hajime Ariga, Jun Zheng, Kirk Ludwig, Christopher Mantyh, Theodore N. Pappas & Toku Takahashi. (2008) Endogenous ghrelin and 5-HT regulate interdigestive gastrointestinal contractions in conscious rats. American Journal of Physiology-Gastrointestinal and Liver Physiology 295:2, pages G403-G411.
Crossref
Hajime Ariga, Kenji Imai, Cindy Chen, Christopher Mantyh, Theodore N. Pappas & Toku Takahashi. (2008) Does ghrelin explain accelerated gastric emptying in the early stages of diabetes mellitus?. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 294:6, pages R1807-R1812.
Crossref
Hajime Ariga, Kenji Imai, Cindy Chen, Christopher Mantyh, Theodore N. Pappas & Toku Takahashi. (2008) Fixed feeding potentiates interdigestive gastric motor activity in rats: importance of eating habits for maintaining interdigestive MMC. American Journal of Physiology-Gastrointestinal and Liver Physiology 294:3, pages G655-G659.
Crossref
Hajime Ariga, Yukiomi Nakade, Kiyoshi Tsukamoto, Kenji Imai, Cindy Chen, Christopher Mantyh, Theodore N. Pappas & Toku Takahashi. (2008) Ghrelin accelerates gastric emptying via early manifestation of antro-pyloric coordination in conscious rats. Regulatory Peptides 146:1-3, pages 112-116.
Crossref
Cemil Tümer, Hüda Diken Oflazoğlu, Basra Deniz Obay, Mustafa Kelle & Ezel Taşdemir. (2008) Effect of ghrelin on gastric myoelectric activity and gastric emptying in rats. Regulatory Peptides 146:1-3, pages 26-32.
Crossref
Wen-Cai Qiu, Zhi-Gang Wang, Ran Lv, Wei-Gang Wang, Xiao-Dong Han, Jun Yan, Yu Wang, Qi Zheng & Kai-Xing Ai. (2008) Ghrelin improves delayed gastrointestinal transit in alloxan-induced diabetic mice. World Journal of Gastroenterology 14:16, pages 2572.
Crossref
Kalina Venkova, Graeme Fraser, Hamid R. Hoveyda & Beverley Greenwood-Van Meerveld. (2007) Prokinetic Effects of a New Ghrelin Receptor Agonist TZP-101 in a Rat Model of Postoperative Ileus. Digestive Diseases and Sciences 52:9, pages 2241-2248.
Crossref
H. Ariga, K. Tsukamoto, C. Chen, C. Mantyh, T. N. Pappas & T. Takahashi. (2007) Endogenous acyl ghrelin is involved in mediating spontaneous phase III‐like contractions of the rat stomach. Neurogastroenterology & Motility 19:8, pages 675-680.
Crossref
Valerio Cigaina & Angelica Lindén Hirschberg. (2007) Plasma ghrelin and gastric pacing in morbidly obese patients. Metabolism 56:8, pages 1017-1021.
Crossref
Daniela Z. Dimitrova, Deyan N. Mihov, Rui Wang, Kiril L. Hristov, Lazar I. Rizov, Thomas B. Bolton & Dessislava B. Duridanova. (2007) Contractile effect of ghrelin on isolated guinea-pig renal arteries. Vascular Pharmacology 47:1, pages 31-40.
Crossref
Ken-ichi Takamori, Yohei Mizuta, Fuminao Takeshima, Yuko Akazawa, Hajime Isomoto, Ken Ohnita, Kazuo Ohba, Katsuhisa Omagari, Saburo Shikuwa & Shigeru Kohno. (2007) Relation Among Plasma Ghrelin Level, Gastric Emptying, and Psychologic Condition in Patients With Functional Dyspepsia. Journal of Clinical Gastroenterology 41:5, pages 477-483.
Crossref
Takio Kitazawa, Hiroyuki Kaiya & Tetsuro Taneike. (2007) Contractile effects of ghrelin-related peptides on the chicken gastrointestinal tract in vitro. Peptides 28:3, pages 617-624.
Crossref
H. S. Sallam, H. M. Oliveira, H. T. Gan, D. N. Herndon & J. D. Z. Chen. (2007) Ghrelin improves burn-induced delayed gastrointestinal transit in rats. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 292:1, pages R253-R257.
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Yohei Mizuta, Saburo Shikuwa, Hajime Isomoto, Ryosuke Mishima, Yuko Akazawa, Jun-ichi Masuda, Katsuhisa Omagari, Fuminao Takeshima & Shigeru Kohno. (2006) Recent insights into digestive motility in functional dyspepsia. Journal of Gastroenterology 41:11, pages 1025-1040.
Crossref
Yasutake Shimizu, Ed C. Chang, Anthony D. Shafton, Dorota M. Ferens, Gareth J. Sanger, Jason Witherington & John B. Furness. (2006) Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat. The Journal of Physiology 576:1, pages 329-338.
Crossref
Anna K. Bassil, Narinder B. Dass & Gareth J. Sanger. (2006) The prokinetic-like activity of ghrelin in rat isolated stomach is mediated via cholinergic and tachykininergic motor neurones. European Journal of Pharmacology 544:1-3, pages 146-152.
Crossref
Susumu Suzuki, Eduardo J.B. Ramos, Carolina G. Goncalves, Chung Chen & Michael M. Meguid. (2005) Changes in GI hormones and their effect on gastric emptying and transit times after Roux-en-Y gastric bypass in rat model. Surgery 138:2, pages 283-290.
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