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Scandinavian Journal of Gastroenterology Volume 53, 2018 - Issue 7
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Original Article

Direct acting antiviral treatment of chronic hepatitis C in Denmark: factors associated with and barriers to treatment initiation

Christina SølundDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark; ;Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; ORCID Iconhttp://orcid.org/0000-0001-8149-3780View further author information
ORCID Icon,
Sofie HallagerDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark; View further author information
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Martin S. PedersenCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; ;Department of Clinical Microbiology, Copenhagen University Hospital, Hvidovre, Denmark; ;Department of Science and Environment, Roskilde University, Roskilde, Denmark; View further author information
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Ulrik FahnøeCopenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
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Anja ErnstDepartment of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark; View further author information
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Henrik B. KrarupDepartment of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark; ;Department of Medical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark; View further author information
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Birgit T. RøgeDepartment of Medicine, Lillebaelt Hospital, Kolding, Denmark; View further author information
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Peer B. ChristensenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark; ;Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark; View further author information
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Alex L. LaursenDepartment of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark; View further author information
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Jan GerstoftDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; ;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
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Erika BélardDepartment of Gastroenterology, Copenhagen University Hospital, Herlev, Denmark; View further author information
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Lone G. MadsenDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; ;Department of Medical Gastroenterology, Zealand University Hospital, Køge, Denmark; View further author information
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Kristian SchønningDepartment of Clinical Microbiology, Copenhagen University Hospital, Hvidovre, Denmark; ;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
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Anders G. PedersenDTU Bioinformatics, Technical University of Denmark, Lyngby, DenmarkView further author information
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Jens BukhDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark; ;Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
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Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark; ;Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Correspondence[email protected]
View further author information
& The DANHEP group show all
Pages 849-856 | Received 06 Feb 2018, Accepted 25 Mar 2018, Published online: 02 May 2018

Citations (16)

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Rafael A. Leiva, Bente M. Bergersen, Ane-Kristine Finbråten, Per Kristian Sandvei, Øystein Simonsen, Carola M. Rosseland, Karin Hagen, Lital Young, R. Scott Roberts, Yngve Mikkelsen, Ravinder Singh, Martin Lagging & Olav Dalgard. (2023) High real-world effectiveness of 12-week elbasvir/grazoprevir without resistance testing in the treatment of patients with HCV genotype 1a infection in Norway. Scandinavian Journal of Gastroenterology 58:3, pages 264-268.
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Leith Morris, Linda Selvey, Owain Williams, Charles Gilks & Andrew Smirnov. (2021) Reasons for Not Seeking Hepatitis C Treatment among People Who Inject Drugs. Substance Use & Misuse 56:2, pages 175-184.
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Articles from other publishers (14)

Anna V. Sherwood, Lizandro R. Rivera-Rangel, Line A. Ryberg, Helena S. Larsen, Klara M. Anker, Rui Costa, Cathrine B. Vågbø, Eva Jakljevič, Long V. Pham, Carlota Fernandez-Antunez, Gabriele Indrisiunaite, Agnieszka Podolska-Charlery, Julius E. R. Grothen, Nicklas W. Langvad, Nicolas Fossat, Anna Offersgaard, Amal Al-Chaer, Louise Nielsen, Anna Kuśnierczyk, Christina Sølund, Nina Weis, Judith M. Gottwein, Kenn Holmbeck, Sandro Bottaro, Santseharay Ramirez, Jens Bukh, Troels K. H. Scheel & Jeppe Vinther. (2023) Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide. Nature 619:7971, pages 811-818.
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Allison E. Wang, Eric Hsieh, Barbara J. Turner & Norah Terrault. (2022) Integrating Management of Hepatitis C Infection into Primary Care: the Key to Hepatitis C Elimination Efforts. Journal of General Internal Medicine 37:13, pages 3435-3443.
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Li-Jen Chang, Han-Cheng Chang, Po-Yueh Chen, Chi-Yi Chen, Kun-Feng Tsai, Koh-Kok Yean, Hsin-Yi Yang, Tsung-Hsien Chen, Pao-Ta Yu, Chu-Kuang Chou & Sheng-Hsuan Chen. (2022) Factors Associated with the Refusal of Direct-Acting Antiviral Agents for the Treatment of Hepatitis C in Taiwan. Medicina 58:4, pages 521.
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Sandra Dröse, Anne Lindebo Holm Øvrehus, Dorte Kinggaard Holm, Lone Wulff Madsen, Belinda Klemmensen Mössner, Jacob Søholm, Janne Fuglsang Hansen, Birgit Thorup Røge & Peer Brehm Christensen. (2022) A multi-level intervention to eliminate hepatitis C from the Region of Southern Denmark: the C-Free-South project. BMC Infectious Diseases 22:1.
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Daan W. Von den Hoff, Floor A. C. Berden, Femke Atsma, Arnt F. A. Schellekens & Joost P. H. Drenth. (2022) Against All Odds? Addiction History Associated with Better Viral Hepatitis Care: A Dutch Nationwide Claims Data Study. Journal of Clinical Medicine 11:4, pages 1146.
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Jorge Valencia, Jeffrey V. Lazarus, Francisco C. Ceballos, Jesús Troya, Guillermo Cuevas, Salvador Resino, Juan Torres‐Macho & Pablo Ryan. (2021) Differences in the hepatitis C virus cascade of care and time to initiation of therapy among vulnerable subpopulations using a mobile unit as point‐of‐care. Liver International 42:2, pages 309-319.
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Philippe J. ZamorAshley BrownDouglas E. DyllaJohn F. DillonAnne F. LuetkemeyerJordan J. FeldDavid MutimerReem GhalibEric CrownSandra S. LovellYiran HuChristophe MorenoDavid R. NelsonMassimo ColomboGeorgios PapatheodoridisJuergen K. RockstrohRichard SkoienEric LawitzIra M. Jacobson. (2021) High Sustained Virologic Response Rates of Glecaprevir/Pibrentasvir in Patients With Dosing Interruption or Suboptimal Adherence. American Journal of Gastroenterology 116:9, pages 1896-1904.
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Peter Buggisch, Hans Heiken, Stefan Mauss, Bernd Weber, Maria-Christina Jung, Herbert Görne, Renate Heyne, Holger Hinrichsen, Dennis Hidde, Bettina König, Ana Gabriela Pires dos Santos, Claus Niederau & Thomas Berg. (2021) Barriers to initiation of hepatitis C virus therapy in Germany: A retrospective, case-controlled study. PLOS ONE 16:5, pages e0250833.
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Ulrik Fahnøe, Martin S. Pedersen, Christina Sølund, Anja Ernst, Henrik B. Krarup, Birgit T. Røge, Peer B. Christensen, Alex L. Laursen, Jan Gerstoft, Peter Thielsen, Lone G. Madsen, Anders G. Pedersen, Kristian Schønning, Nina Weis & Jens Bukh. (2020) Global evolutionary analysis of chronic hepatitis C patients revealed significant effect of baseline viral resistance, including novel non‐target sites, for DAA‐based treatment and retreatment outcome. Journal of Viral Hepatitis 28:2, pages 302-316.
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Marjan Javanbakht, Roxanne Archer & Jeffrey Klausner. (2020) Will prior health insurance authorization for medications continue to hinder hepatitis C treatment delivery in the United States? Perspectives from hepatitis C treatment providers in a large urban healthcare system. PLOS ONE 15:11, pages e0241615.
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Jeffrey Victor Lazarus, Anne Øvrehus, Jonas Demant, Louise Krohn-Dehli & Nina Weis. (2020) The Copenhagen test and treat hepatitis C in a mobile clinic study: a protocol for an intervention study to enhance the HCV cascade of care for people who inject drugs (T’N’T HepC). BMJ Open 10:11, pages e039724.
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Davoud Pourmarzi, Lisa Hall, Andrew Smirnov, Julie Hepworth, Tony Rahman & Gerard FitzGerald. (2020) Framework for community-based models for treating hepatitis C virus. Australian Health Review 44:3, pages 459.
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Iuliia Makarenko, Adelina Artenie, Stine Hoj, Nanor Minoyan, Brendan Jacka, Geng Zang, Gillian Barlett, Didier Jutras-Aswad, Valerie Martel-Laferriere & Julie Bruneau. (2019) Transitioning from interferon-based to direct antiviral treatment options: A potential shift in barriers and facilitators of treatment initiation among people who use drugs?. International Journal of Drug Policy 72, pages 69-76.
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Sanne Brun Jensen, Ulrik Fahnøe, Long V. Pham, Stéphanie Brigitte Nelly Serre, Qi Tang, Lubna Ghanem, Martin Schou Pedersen, Santseharay Ramirez, Daryl Humes, Anne Finne Pihl, Jonathan Filskov, Christina Søhoel Sølund, Julia Dietz, Slim Fourati, Jean‐Michel Pawlotsky, Christoph Sarrazin, Nina Weis, Kristian Schønning, Henrik Krarup, Jens Bukh & Judith Margarete Gottwein. (2019) Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants. Hepatology 70:3, pages 771-787.
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