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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 1
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Original Articles

Convenient One‐Pot Heterogeneous Catalytic Method for the Preparation of 3,4‐Dihydropyrimidin‐2(1H)‐ones

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Pages 129-136 | Received 01 Jun 2005, Published online: 21 Aug 2006

Keep up to date with the latest research on this topic with citation updates for this article.

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Fatemeh Samandi Zadeh, Mohammad Kazem Mohammadi, Ayeh Rayatzadeh & Neda Hasanzadeh. (2023) One pot synthesis of bis (dihydropyrimidinone) and tetrahydro-4H-chromenes derivatives using Ag2O/GO/TiO2 composite nanostructure. Inorganic and Nano-Metal Chemistry 53:1, pages 8-18.
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Susheel Gulati, Rajvir Singh, Jayant Sindhu & Suman Sangwan. (2020) Eco-friendly Preparations of Heterocycles Using Fruit Juices as Catalysts: A Review. Organic Preparations and Procedures International 52:5, pages 381-395.
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Anna Takács, Anna Fodor, János Németh & Zoltán Hell. (2014) Zeolite-Catalyzed Method for the Preparation of 2,3-Dihydroquinazolin-4(1H)-ones. Synthetic Communications 44:15, pages 2269-2275.
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M. Syamala. (2009) Recent Progress in Three-Component Reactions. An Update. Organic Preparations and Procedures International 41:1, pages 1-68.
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Sirirat Chancharunee, Pilaiwan Pinhom, Manat Pohmakotr & Patrick Perlmutter. (2009) One-Pot Synthesis of 3,4-Dihydropyrimidine-2-(1H)-ones Using CsF–Celite as Catalyst. Synthetic Communications 39:5, pages 880-886.
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Articles from other publishers (26)

Vinay Kumar, Rituparna Saha, Satyaki Chatterjee & Vivek Mishra. (2023) From traditional to greener alternatives: potential of plant resources as a biotransformation tool in organic synthesis. Reaction Chemistry & Engineering 8:11, pages 2677-2688.
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Tejas M. Dhameliya, Prinsa R. Nagar, Kaushikkumar A. Bhakhar, Hevankumar R. Jivani, Bhavya J. Shah, Khushi M. Patel, Vaishnavi S. Patel, Archita H. Soni, Lipi P. Joshi & Normi D. Gajjar. (2022) Recent advancements in applications of ionic liquids in synthetic construction of heterocyclic scaffolds: A spotlight. Journal of Molecular Liquids 348, pages 118329.
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Vinod K. Tiwari, Abhijeet Kumar, Sanchayita Rajkhowa, Garima Tripathi & Anil Kumar SinghVinod K. Tiwari, Abhijeet Kumar, Sanchayita Rajkhowa, Garima Tripathi & Anil Kumar Singh. 2022. Green Chemistry. Green Chemistry 207 260 .
Shima Zangeneh Yousef Abadi, Mohammad Kazem Mohammadi & Haman Tavakkoli. (2021) Tri Oxometallic Zeolite Composite Nanostructures: New and Efficient Catalyst for Solvent Free Synthesis of Bis (Dihydropyrimidinone) Derivatives. Journal of Inorganic and Organometallic Polymers and Materials 31:7, pages 2949-2958.
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Elon F. Freitas, Roberto Y. Souza, Saulo T. A. Passos, José A. Dias, Silvia C. L. Dias & Brenno A. D. Neto. (2019) Tuning the Biginelli reaction mechanism by the ionic liquid effect: the combined role of supported heteropolyacid derivatives and acidic strength. RSC Advances 9:46, pages 27125-27135.
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Rajendra V. Patil, Jagdish U. Chavan, Dipak S. Dalal, Vaishali S. Shinde & Anil G. Beldar. (2019) Biginelli Reaction: Polymer Supported Catalytic Approaches. ACS Combinatorial Science 21:3, pages 105-148.
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Mohammad Taqi Jafari‐Chermahini & Hossein Tavakol. (2019) Immobilized Gelatin–λ–Carrageenan on Magnetite Nanoparticles as an Efficient Organocatalyst for Enantioselective Biginelli Reaction. ChemistrySelect 4:6, pages 1895-1902.
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Samira Kazemi, Akbar Mobinikhaledi & Mojgan Zendehdel. (2017) NaY Zeolite Functionalized by Sulfamic Acid/Cu(OAc) 2 as a Novel and Reusable Heterogeneous Hybrid Catalyst in Efficient Synthesis of Bis, Tris, and Tetrakis(indolyl)methanes, 3,4-Dihydropyrimidin-2(1 H )-ones, and 2-Aryl-1 H -benzothiazoles . Journal of the Chinese Chemical Society 64:7, pages 764-776.
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M. Afradi, N. Foroughifar, H. Pasdar & H. Moghanian. (2016) l -proline N-sulfonic acid-functionalized magnetic nanoparticles: a novel and magnetically reusable catalyst for one-pot synthesis of 3,4-dihydropyrimidine-2-(1H)-thiones under solvent-free conditions . RSC Advances 6:64, pages 59343-59351.
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Zarrin Ghasemi, Farzaneh Farshbaf Orafa, Mahtab Pirouzmand, Gholamreza Zarrini, Behnaz Nikzad Kojanag & Roya Salehi. (2015) Zn2+/MCM-41 catalyzed Biginelli reaction of heteroaryl aldehydes and evaluation of the antimicrobial activity and cytotoxicity of the pyrimidone products. Tetrahedron Letters 56:46, pages 6393-6396.
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B. Karami, K. Eskandari, Z. Zare & S. Gholipour. (2014) A New Access to 1,8-Dioxooctahydroxanthenes Using Yttrium(III) Nitrate Hexahydrate and Tin(II) Chloride Dihydrate as Effective and Reusable Catalysts. Chemistry of Heterocyclic Compounds 49:12, pages 1715-1722.
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Luciana M. Ramos, Adrian Y. Ponce de Leon y Tobio, Marcelo R. dos Santos, Heibbe C. B. de Oliveira, Alexandre F. Gomes, Fabio C. Gozzo, Aline L. de Oliveira & Brenno A. D. Neto. (2012) Mechanistic Studies on Lewis Acid Catalyzed Biginelli Reactions in Ionic Liquids: Evidence for the Reactive Intermediates and the Role of the Reagents. The Journal of Organic Chemistry 77:22, pages 10184-10193.
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Maria José Climent, Avelino Corma & Sara Iborra. (2012) Homogeneous and heterogeneous catalysts for multicomponent reactions. RSC Adv. 2:1, pages 16-58.
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Kawaljit Singh & Kamaljit Singh. 2012. 223 308 .
Gopalakrishnan Aridoss & Yeon-Tae Jeong. (2010) A Convenient One-Pot Biginelli Reaction Catalyzed by Y(OAc) 3 : An Improved Protocol for the Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and Their Sulfur Analogues . Bulletin of the Korean Chemical Society 31:4, pages 863-868.
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Maria Mar Sanchez del Duque, Christophe Allais, Nicolas Isambert, Thierry Constantieux & Jean Rodriguez. 2010. Synthesis of Heterocycles via Multicomponent Reactions I. Synthesis of Heterocycles via Multicomponent Reactions I 227 277 .
Vinod Tribhuvannathji Kamble, Dnyanoba Baburao Muley, Sandeep Tukaram Atkore & Sharad Digambarrao Dakore. (2010) Three Component Reaction: An Efficient Synthesis of 3,4‐Dihydropyrimidin‐2(1 H )‐ones and Thiones Using Heterogeneous Catalyst . Chinese Journal of Chemistry 28:3, pages 388-392.
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Maksim A. Kolosov, Valeriy D. Orlov, Dmitriy A. Beloborodov & Victor V. Dotsenko. (2008) A chemical placebo: NaCl as an effective, cheapest, non-acidic and greener catalyst for Biginelli-type 3,4-dihydropyrimidin-2(1H)-ones (-thiones) synthesis. Molecular Diversity 13:1, pages 5-25.
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Okram Mukherjee Singh, Sarangthem Joychandra Singh, Mutum Babita Devi, Laitonjam Nalini Devi, Nameirakpam Irabanta Singh & Sang-Gyeong Lee. (2008) Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones. Bioorganic & Medicinal Chemistry Letters 18:24, pages 6462-6467.
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Mojgan Zendehdel, A. Mobinikhaledi & A. Asgari. (2008) Zeolite an efficient catalyst for the Biginelli condensation reaction. Journal of Inclusion Phenomena and Macrocyclic Chemistry 60:3-4, pages 353-357.
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Adrienn Hegedüs, Zoltán Hell, Tamás Vargadi, Attila Potor & Iván Gresits. (2007) A new, simple synthesis of 1,2-dihydroquinolines via cyclocondensation using zeolite catalyst. Catalysis Letters 117:3-4, pages 99-101.
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Raman Gupta, Monika Gupta, Satya Paul & Rajive Gupta. (2007) Silica-supported ZnCl 2 — A highly active and reusable heterogeneous catalyst for the one-pot synthesis of dihydropyrimidinones–thiones . Canadian Journal of Chemistry 85:3, pages 197-201.
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Herman van Bekkum & Herman W. Kouwenhoven. 2007. Introduction to Zeolite Science and Practice. Introduction to Zeolite Science and Practice 947 998 .
Adrienn Hegedüs & Zoltán Hell. (2006) Zeolite-catalyzed Pechmann synthesis of coumarins. Catalysis Letters 112:1-2, pages 105-108.
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Adrienn Hegedues, Zoltan Hell & Ilona Vigh. (2006) Convenient One‐Pot Heterogeneous Catalytic Method for the Preparation of 3,4‐Dihydropyrimidin‐2(1H)‐ones.. ChemInform 37:22.
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Adrienn Hegedüs & Zoltán Hell. (2006) Zeolite-catalyzed simple synthesis of isochromans via the oxa-Pictet–Spengler reaction. Organic & Biomolecular Chemistry 4:7, pages 1220.
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