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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 11
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Original Articles

Application of Sulfinyl bis(2,4‐dihydroxythiobenzoyl) in the Synthesis of N‐Substituted 2‐Amino‐5‐(2,4‐dihydroxyphenyl)‐1,3,4‐thiadiazoles

Joanna Matysiak Department of Chemistry, Agricultural University, Lublin, PolandCorrespondence[email protected]
&
Andrzej Niewiadomy Department of Chemistry, Agricultural University, Lublin, Poland
Pages 1621-1630 | Received 10 Oct 2005, Published online: 21 Aug 2006

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Joanna Matysiak, Alicja Skrzypek, Monika Karpińska, Urszula Głaszcz, Andrzej Niewiadomy, Beata Paw, Bogusław Senczyna, Joanna Wietrzyk & Dagmara Kłopotowska. (2016) Synthesis and antiproliferative activity of some N′-substituted 2,4-dihydroxybenzothiohydrazides. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup3, pages 166-172.
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Alicja Skrzypek, Joanna Matysiak, Monika M. Karpińska & Andrzej Niewiadomy. (2013) Synthesis and anticholinesterase activities of novel 1,3,4-thiadiazole based compounds. Journal of Enzyme Inhibition and Medicinal Chemistry 28:4, pages 816-823.
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Mohamed A. Metwally, Samir Bondock, Hossam El-Azap & Ez-Eldin M. Kandeel. (2011) Thiosemicarbazides: synthesis and reactions. Journal of Sulfur Chemistry 32:5, pages 489-519.
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Articles from other publishers (26)

Aimar Gonzalo-Barquero, Bénédicte Lepoittevin, Jacques Rouden & Jérôme Baudoux. (2023) Synthesis and Reactivity of Fluorinated Dithiocarboxylates to Prepare Thioamides—Effective Access to a 4-Styrenylthioamide-Cinchona Alkaloid Monomer. Molecules 28:21, pages 7333.
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Alicja Skrzypek, Monika Karpińska, Małgorzata Juszczak, Aneta Grabarska, Joanna Wietrzyk, Elżbieta Krajewska-Kułak, Marek Studziński, Tadeusz Paszko & Joanna Matysiak. (2022) Cholinesterases Inhibition, Anticancer and Antioxidant Activity of Novel Benzoxazole and Naphthoxazole Analogs. Molecules 27:23, pages 8511.
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Alicja Skrzypek, Joanna Matysiak, Monika Karpińska, Kamila Czarnecka, Paweł Kręcisz, Dorota Stary, Jędrzej Kukułowicz, Beata Paw, Marek Bajda, Paweł Szymański & Andrzej Niewiadomy. (2021) Biological evaluation and molecular docking of novel 1,3,4-thiadiazole-resorcinol conjugates as multifunctional cholinesterases inhibitors. Bioorganic Chemistry 107, pages 104617.
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Alaa A. Hassan, Ashraf A. Aly, Nasr K. Mohamed, Lamiaa E. Abd El-Haleem, Stefan Bräse & Martin Nieger. (2020) Tetracyanoethylene as a building block in the facile synthesis of heteroyl-tetrasubstituted thiazoles. Monatshefte für Chemie - Chemical Monthly 151:9, pages 1425-1431.
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Joanna Matysiak, Alicja Skrzypek, Monika Karpińska, Kamila Czarnecka, Paweł Szymański, Marek Bajda & Andrzej Niewiadomy. (2019) Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1H- Benzimidazole Analogues. Biomolecules 9:12, pages 870.
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Joanna Matysiak, Monika M. Karpińska, Alicja Skrzypek, Joanna Wietrzyk, Dagmara Kłopotowska, Andrzej Niewiadomy, Beata Paw, Małgorzata Juszczak & Wojciech Rzeski. (2019) Design, synthesis and antiproliferative activity against human cancer cell lines of novel benzo-, benzofuro-, azolo- and thieno-1,3-thiazinone resorcinol hybrids. Arabian Journal of Chemistry 12:8, pages 2655-2667.
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J. Matysiak, A. Skrzypek, A. Niewiadomy, M. M. Karpińska, J. Wietrzyk, B. Paw & D. Kłopotowska. (2016) Synthesis of 4-(4-methylidene-4H-3,1-benzothiazin-2-yl)benzene1,3-diols and their antiproliferative activity against human cancer cell lines. Russian Journal of Bioorganic Chemistry 42:1, pages 93-99.
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Joanna Matysiak, Małgorzata Juszczak, Monika M. Karpińska, Ewa Langner, Katarzyna Walczak, Marta K. Lemieszek, Alicja Skrzypek, Andrzej Niewiadomy & Wojciech Rzeski. (2015) Synthesis of 2-(2,4-dihydroxyphenyl)thieno-1,3-thiazin-4-ones, their lipophilicity and anticancer activity in vitro. Molecular Diversity 19:4, pages 725-736.
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Joanna Matysiak, Małgorzata Juszczak, Monika M. Karpińska, Ewa Langner, Katarzyna Walczak, Marta Lemieszek, Alicja Skrzypek, Wojciech Rzeski & Andrzej Niewiadomy. (2015) Synthesis, characterization, and pharmacological evaluation of novel azolo- and azinothiazinones containing 2,4-dihydroxyphenyl substituent as anticancer agents. Monatshefte für Chemie - Chemical Monthly 146:8, pages 1315-1327.
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Jarogniew J. Luszczki, Monika Karpińska, Joanna Matysiak & Andrzej Niewiadomy. (2015) Characterization and preliminary anticonvulsant assessment of some 1,3,4-thiadiazole derivatives. Pharmacological Reports 67:3, pages 588-592.
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G. Raszewski, M. Juszczak, M. K. Lemieszek, J. Matysiak, A. Niewiadomy & W. Rzeski. (2014) A simple HPLC method for determining 2-(3-chlorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole in brain and plasma of animals: Application to a pharmacokinetic study. Acta Chromatographica 26:2, pages 255-266.
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Syeda Sohaila Naz, Nazar Ul Islam, Muhammad Raza Shah, Syed Sartaj Alam, Zafar Iqbal, Massimo Bertino, Louis Franzel & Afifa Ahmed. (2013) Enhanced biocidal activity of Au nanoparticles synthesized in one pot using 2, 4-dihydroxybenzene carbodithioic acid as a reducing and stabilizing agent. Journal of Nanobiotechnology 11:1.
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Wafaa S. Hamama, Moustafa A. Gouda, Marwa H. Badr & Hanafi H. Zoorob. (2012) Synthesis, antioxidant, and antitumor evaluation of certain new N-substituted-2-amino-1,3,4-thiadiazoles. Medicinal Chemistry Research 22:8, pages 3556-3565.
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Alicja Skrzypek, Joanna Matysiak, Andrzej Niewiadomy, Marek Bajda & Paweł Szymański. (2013) Synthesis and biological evaluation of 1,3,4-thiadiazole analogues as novel AChE and BuChE inhibitors. European Journal of Medicinal Chemistry 62, pages 311-319.
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Monika M. Karpińska, Joanna Matysiak, Andrzej Niewiadomy, Joanna Wietrzyk & Dagmara Kłopotowska. (2011) Synthesis and biological activity of novel 4- and 6-(1-alkyl/aryl-1H-benzimidazol-2-yl)benzene-1,3-diols. Monatshefte für Chemie - Chemical Monthly 143:2, pages 269-276.
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Renata Los, Marta Wesołowska‐Trojanowska, Anna Malm, Monika M. Karpińska, Joanna Matysiak, Andrzej Niewiadomy & Urszula Głaszcz. (2012) A new approach to the synthesis of 2‐aryl‐substituted benzimidazoles, quinazolines, and other related compounds and their antibacterial activity. Heteroatom Chemistry 23:3, pages 265-275.
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Joanna Matysiak, Monika M. Karpińska, Andrzej Niewiadomy, Joanna Wietrzyk & Dagmara Kłopotowska. (2012) One-Pot Synthesis of New (1,3-Thiazolo[5,4-b]pyridin-2-yl)benzenediols and Their Antiproliferative Activities against Human Cancer Cell Lines. Chemistry & Biodiversity 9:1, pages 48-57.
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Monika M. Karpińka, Joanna Matysiak & Andrzej Niewiadomy. (2011) Synthesis of novel 4-(1H-benzimidazol-2-yl)benzene-1,3-diols and their cytotoxic activity against human cancer cell lines. Archives of Pharmacal Research 34:10, pages 1639-1647.
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Alaa A. Hassan & Ahmed M. Shawky. (2011) Thiosemicarbazides in heterocyclization. Journal of Heterocyclic Chemistry 48:3, pages 495-516.
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Xi Cun Wang, Xiao Mei Ding, Sheng Qing Wang, Xue Fei Chen & Zheng Jun Quan. (2010) Synthesis of 2-(N-formyl)-5-aryl/aryloxymethyl-1,3,4-thiadiazoles with potential bioactivity in PEG-400. Chinese Chemical Letters 21:3, pages 301-304.
Crossref
Joanna Matysiak, Alicja Skrzypek & Andrzej Niewiadomy. (2010) Synthesis and antifungal activity of novel 5‐substituted 4‐(1,3,4‐thiadiazol‐2‐yl)benzene‐1,3‐diols. Heteroatom Chemistry 21:7, pages 533-540.
Crossref
Joanna Matysiak. (2008) QSAR of Antiproliferative Activity of N ‐Substituted 2‐Amino‐5‐(2,4‐dihydroxyphenyl)‐1,3,4‐thiadiazoles in Various Human Cancer Cells . QSAR & Combinatorial Science 27:5, pages 607-617.
Crossref
J. Matysiak & Z. Malinski. (2007) 2-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole analogues: Antifungal activity in vitro against Candida species. Russian Journal of Bioorganic Chemistry 33:6, pages 594-601.
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Wojciech Rzeski, Joanna Matysiak & Martyna Kandefer-Szerszeń. (2007) Anticancer, neuroprotective activities and computational studies of 2-amino-1,3,4-thiadiazole based compound. Bioorganic & Medicinal Chemistry 15:9, pages 3201-3207.
Crossref
Joanna Matysiak & Andrzej Niewiadomy. (2006) Application of Sulfinyl Bis(2,4‐dihydroxythiobenzoyl) in the Synthesis of N‐Substituted 2‐Amino‐5‐(2,4‐dihydroxyphenyl)‐1,3,4‐thiadiazoles.. ChemInform 37:43.
Crossref
Joanna Matysiak. (2006) Evaluation of Antiproliferative Effect in Vitro of Some 2-Amino-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole Derivatives. Chemical and Pharmaceutical Bulletin 54:7, pages 988-991.
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