Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 23
810
Views
18
CrossRef citations to date
0
Altmetric
Original Articles

Practical Synthesis of N‐Alkyl‐N‐alkyloxycarbonylaminomethyl Prodrug Derivatives of Acetaminophen, Theophylline, and 6‐Mercaptopurine

&
Pages 3537-3548 | Received 09 May 2006, Published online: 24 Nov 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

N. Hussain Basha, K. Narendra Babu, P. Siva Shanker, G. Dinneswara Reddy, A. Padmaja & V. Padmavathi. (2022) Synthesis of Pyrimidinyl Benzazolyl Urea Derivatives as Antimicrobial and Antioxidant Agents. Polycyclic Aromatic Compounds 42:10, pages 7321-7335.
Read now
Weike Su, Yiyi Weng, Cun Zheng, Ying Zhang, Fei Shi, Bin Hong, Zhiwei Chen, Jianjun Li & Zhenhua Li. (2009) Recent Developments in the Use of bis-(Trichloromethyl) Carbonate in Synthesis. Organic Preparations and Procedures International 41:2, pages 93-141.
Read now

Articles from other publishers (16)

Vladimir V. Kouznetsov. (2024) Exploring acetaminophen prodrugs and hybrids: a review. RSC Advances 14:14, pages 9691-9715.
Crossref
Narendra Babu Kayathi, Siva Sankar Panga, Padmaja Adivireddy & Padmavathi Venkatapuram. (2021) A green approach for the synthesis of benzazolyl pyrimidinyl carbamothioates under ultrasonication and their antimicrobial activity. Journal of the Iranian Chemical Society 18:11, pages 2931-2943.
Crossref
Kosuke Ohsawa, Shota Ochiai, Junya Kubota & Takayuki Doi. (2020) Gold-Catalyzed Amide/Carbamate-Linked N , O -Acetal Formation with Bulky Amides and Alcohols . The Journal of Organic Chemistry 86:1, pages 1281-1291.
Crossref
Alexandra Pastor, Arnaud Machelart, Xue Li, Nicolas Willand, Alain Baulard, Priscille Brodin, Ruxandra Gref & Didier Desmaële. (2019) A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation. Organic & Biomolecular Chemistry 17:20, pages 5129-5137.
Crossref
Kayathi Narendra Babu, Tamatam Rekha, G. Sravya, Putta Ramachandra Reddy, Venkatapuram Padmavathi & Grigory V. Zyryanov. Synthesis and antimicrobial activity of bis(azolyl) urea derivatives. Synthesis and antimicrobial activity of bis(azolyl) urea derivatives.
Robert V. Kolakowski, Karl T. Haelsig, Kim K. Emmerton, Chris I. Leiske, Jamie B. Miyamoto, Julia H. Cochran, Robert P. Lyon, Peter D. Senter & Scott C. Jeffrey. (2016) The Methylene Alkoxy Carbamate Self‐Immolative Unit: Utilization for the Targeted Delivery of Alcohol‐Containing Payloads with Antibody–Drug Conjugates. Angewandte Chemie International Edition 55:28, pages 7948-7951.
Crossref
Robert V. Kolakowski, Karl T. Haelsig, Kim K. Emmerton, Chris I. Leiske, Jamie B. Miyamoto, Julia H. Cochran, Robert P. Lyon, Peter D. Senter & Scott C. Jeffrey. (2016) The Methylene Alkoxy Carbamate Self‐Immolative Unit: Utilization for the Targeted Delivery of Alcohol‐Containing Payloads with Antibody–Drug Conjugates. Angewandte Chemie 128:28, pages 8080-8083.
Crossref
O. Andreea Cojocaru, Katharina Bica, Gabriela Gurau, Asako Narita, Parker D. McCrary, Julia L. Shamshina, Patrick S. Barber & Robin D. Rogers. (2013) Prodrug ionic liquids: functionalizing neutral active pharmaceutical ingredients to take advantage of the ionic liquid form. MedChemComm 4:3, pages 559.
Crossref
Susruta Majumdar, Maren Mueller-Spaeth & Kenneth B. Sloan. (2012) Prodrugs of Theophylline Incorporating Ethyleneoxy Groups in the Promoiety: Synthesis, Characterization, and Transdermal Delivery. AAPS PharmSciTech 13:3, pages 853-862.
Crossref
Nicholas C. Boaz, Nathaniel C. Bair, Thanh T. Le & Timothy J. Peelen. (2010) Activation of Fmoc-Protected N , O -Acetals Using Trimethylsilyl Halides: Mechanistic and Synthetic Studies . Organic Letters 12:11, pages 2464-2467.
Crossref
Jesús Hierrezuelo, J. Manuel López-Romero, Rodrigo Rico, José Brea, M. Isabel Loza, Chengzhi Cai & Manuel Algarra. (2010) Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors. Bioorganic & Medicinal Chemistry 18:6, pages 2081-2088.
Crossref
Venkataraman Subramanian. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Takushi Kaneko, Karina Romero, Bryan Li & Richard Buzon. (2007) Novel tethers in ketolide antibiotics. Bioorganic & Medicinal Chemistry Letters 17:18, pages 5049-5053.
Crossref
Susruta Majumdar & K.B. Sloan. (2007) Synthesis and topical delivery of N-alkyl-N-alkyloxycarbonylaminomethyl prodrugs of a model phenolic drug: Acetaminophen. International Journal of Pharmaceutics 337:1-2, pages 48-55.
Crossref
Susruta Majumdar & K.B. Sloan. (2007) Topical delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of theophylline (ThH). International Journal of Pharmaceutics 332:1-2, pages 64-71.
Crossref
Susruta Majumdar & Kenneth B. Sloan. (2007) N-Alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of carboxylic acid containing drugs. Bioorganic & Medicinal Chemistry Letters 17:5, pages 1447-1450.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.