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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 13
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Original Articles

Knoevenagel Condensation of Aromatic Aldehydes with Active Methylene Compounds using a Catalytic Amount of Iodine and K2CO3 at Room Temperature

Yi‐Ming Ren Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, China
&
Chun Cai Chemical Engineering College, Nanjing University of Science and Technology, Nanjing, ChinaCorrespondence[email protected]
Pages 2209-2213 | Received 27 Sep 2006, Published online: 03 Jul 2007

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Xiaoyu Zhang, Xiaoyan He & Sanhu Zhao. (2021) Preparation of a novel Fe3O4@SiO2@propyl@DBU magnetic core–shell nanocatalyst for Knoevenagel reaction in aqueous medium. Green Chemistry Letters and Reviews 14:1, pages 85-98.
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Sanhu Zhao, Dan Meng, Lingling Wei, Yongsheng Qiao & Fugui Xi. (2019) Novel DBU-based hydroxyl ionic liquid for efficient Knoevenagel reaction in water. Green Chemistry Letters and Reviews 12:3, pages 271-277.
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Faryal Chaudhry, Nadia Asif, Syed Salman Shafqat, Amir Azam Khan, Munawar Ali Munawar & Misbahul Ain Khan. (2016) Efficient ecofriendly synthesis of pyrazole acryloyl analogs by amino acid catalysis. Synthetic Communications 46:8, pages 701-709.
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M.B. Deshmukh, SureshS. Patil, S.D. Jadhav & P.B. Pawar. (2012) Green Approach for Knoevenagel Condensation of Aromatic Aldehydes with Active Methylene Group. Synthetic Communications 42:8, pages 1177-1183.
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Zhongqiang Zhou & Yong Sun. (2011) Simple, Efficient, and Green Procedure for the Knoevenagel Condensation Catalyzed by Ethylenediammonium Diacetate Under Solvent-Free Conditions. Synthetic Communications 41:21, pages 3162-3168.
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Zhongqiang Zhou, Jiangyong Yuan & Rong Yang. (2009) Efficient Knoevenagel Condensation Catalyzed by 2-Hydroxyethylammonium Acetate Under Solvent-Free Conditions at Room Temperature. Synthetic Communications 39:11, pages 2001-2007.
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Martin Breugst & Daniel von der Heiden. (2018) Mechanisms in Iodine Catalysis. Chemistry – A European Journal 24:37, pages 9187-9199.
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João Batista M. de Resende Filho, Gilvan P. Pires, João Marcos Gomes de Oliveira Ferreira, Ercules E. S. Teotonio & Juliana A. Vale. (2016) Knoevenagel Condensation of Aldehydes and Ketones with Malononitrile Catalyzed by Amine Compounds-Tethered Fe3O4@SiO2 Nanoparticles. Catalysis Letters 147:1, pages 167-180.
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SURESH PATIL, SWATI D JADHAV & M B DESHMUKH. (2013) Calcined eggshell (CES): An efficient natural catalyst for Knoevenagel condensation under aqueous condition. Journal of Chemical Sciences 125:4, pages 851-857.
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BANDITA DATTA & MOHAMED AFZAL PASHA. (2013) I2/K2CO3: An efficient catalyst for the synthesis of 5-aryl-2,6-dicyano-3-methylanilines. Journal of Chemical Sciences 125:2, pages 291-294.
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R. Motamedi. (2013) Solvent-free synthesis of novel 5-oxo-5H-chromeno[4,3-b]pyridine derivatives. Chemistry of Heterocyclic Compounds 48:12, pages 1839-1843.
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Sanhu Zhao, Xiaoju Wang & Liwei Zhang. (2013) Rapid and efficient Knoevenagel condensation catalyzed by a novel protic ionic liquid under ultrasonic irradiation. RSC Advances 3:29, pages 11691.
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Zeba N. Siddiqui, T. N. Mohammed Musthafa, Shagufta Praveen & Farheen Farooq. (2010) Zn(Proline)2-catalyzed Knoevenagel condensation under solvent-free/aqueous conditions and biological evaluation of products. Medicinal Chemistry Research 20:9, pages 1438-1444.
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Yi-Ming Ren & Chun Cai. (2011) The Michael Addition of Active Methylene Compounds to Chalcone Derivatives using a Catalytic Amount of Iodine and K 2 CO 3 at Room Temperature . Journal of Chemical Research 35:3, pages 176-178.
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Sadok LetaiefYun LiuChristian Detellier. (2011) Zirconium oxide nanoparticles coated on sepiolite by sol–gel process — Their application as a solvent-free catalyst for condensation reactions. Canadian Journal of Chemistry 89:3, pages 280-288.
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Marjan Jereb, Dejan Vražič & Marko Zupan. (2011) Iodine-catalyzed transformation of molecules containing oxygen functional groups. Tetrahedron 67:7, pages 1355-1387.
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Zhong-Xian Li, Xiao-Pei Liu, Zhen Qiu, Dan Xu & Xue-Jun Yu. (2011) An Efficient Iodine-Catalysed Knoevenagel Condensation Reaction in the Presence of Acetic Anhydride. Journal of Chemical Research 35:1, pages 35-36.
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Li-Yan Zeng & Chun Cai. (2009) Iodine Catalyzed One-Pot Multicomponent Synthesis of a Library of Compounds Containing Tetrazolo[1,5- a ]pyrimidine Core . Journal of Combinatorial Chemistry 12:1, pages 35-40.
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An-Guo Ying, Li-Min Wang, Le-Le Wang, Xin-Zhi Chen & Wei-Dong Ye. (2010) Green and Efficient Knoevenagel Condensation Catalysed by a DBU Based ionic Liquid in Water. Journal of Chemical Research 34:1, pages 30-33.
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Manas Chakrabarty, Ajanta Mukherji, Shiho Arima, Yoshihiro Harigaya & Guillaume Pilet. (2008) Expeditious reaction of ninhydrin with active methylene compounds on montmorillonite K10 clay. Monatshefte für Chemie - Chemical Monthly 140:2, pages 189-197.
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Manas Chakrabarty, Ratna Mukherjee, Shiho Arima & Yoshihiro Harigaya. (2009) Reaction of Isatins with Active Methylene Compounds on Neutral Alumina: Formation of Knoevenagel Condensates and Other Interesting Products. HETEROCYCLES 78:1, pages 139.
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Yi-Ming Ren & Chun Cai. (2008) Three-components condensation catalyzed by molecular iodine for the synthesis of 2,4,6-triarylpyridines and 5-unsubstituted-3,4-dihydropyrimidin-2(1H)-ones under solvent-free conditions. Monatshefte für Chemie - Chemical Monthly 140:1, pages 49-52.
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Yi-Ming Ren & Chun Cai. (2008) Convenient and efficient method for synthesis of substituted 2-amino-2-chromenes using catalytic amount of iodine and K2CO3 in aqueous medium. Catalysis Communications 9:6, pages 1017-1020.
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Yi-Ming Ren, Yi-Zhong Zhu & Chun Cai. (2008) Iodine/aqueous NH 4 OAc: An Improved Reaction System for Direct Oxidative Conversion of Aldehydes and Alcohols Into Nitriles . Journal of Chemical Research 2008:1, pages 18-19.
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Yi‐Ming Ren & Chun Cai. (2007) ChemInform Abstract: Knoevenagel Condensation of Aromatic Aldehydes with Active Methylene Compounds Using a Catalytic Amount of Iodine and K 2 CO 3 at Room Temperature. . ChemInform 39:1.
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