Synthesis of 2[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-yl)propyl]-4-[4-tetrafluoropropoxy)phenyl]-3-(2H,4H)-1,2,4-triazol-3-thione—A Novel and Potent Azole Antifungal Agent

Jitendra A. Sattigeri Medicinal Chemistry, New Drug Discovery Research, Ranbaxy Research Laboratory, Haryana, IndiaCorrespondence[email protected]

Sachin Sethi Medicinal Chemistry, New Drug Discovery Research, Ranbaxy Research Laboratory, Haryana, India

Mohammad Salman Ranbaxy Inc., Princeton, New Jersey, USA

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Jyothis Devasia, Aatika Nizam & Vasantha V. L.. (2022) Azole-Based Antibacterial Agents: A Review on Multistep Synthesis Strategies and Biology. Polycyclic Aromatic Compounds 42:8, pages 5474-5495.
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Elham Ghobadi, Shahnaz Saednia & Saeed Emami. (2022) Synthetic approaches and structural diversity of triazolylbutanols derived from voriconazole in the antifungal drug development. European Journal of Medicinal Chemistry 231, pages 114161.
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Jitendra A. Sattigeri, Sachin Sethi & Mohammad Salman. (2010) ChemInform Abstract: Synthesis of 2[(1R,2R)‐2‐(2,4‐difluorophenyl)‐2‐hydroxy‐1‐methyl‐3‐ (1H‐1,2,4‐triazol‐yl)propyl]‐4‐ [4‐tetrafluoropropoxyphenyl]‐3‐(2H,4H)‐1,2,4‐triazol‐3‐thione — A Novel and Potent Azole Antifungal Agent.. ChemInform 41:32.
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Synthesis of 2[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-yl)propyl]-4-[4-tetrafluoropropoxy)phenyl]-3-(2H,4H)-1,2,4-triazol-3-thione—A Novel and Potent Azole Antifungal Agent

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Synthesis of 2[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-yl)propyl]-4-[4-tetrafluoropropoxy)phenyl]-3-(2H,4H)-1,2,4-triazol-3-thione—A Novel and Potent Azole Antifungal Agent

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