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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 40, 2010 - Issue 17
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Original Articles

Simple and Efficient Synthesis of Belinostat

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Pages 2520-2524 | Received 05 May 2009, Published online: 05 Aug 2010

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Yiming Chen, Lihui Zhang, Lin Zhang, Qixiao Jiang & Lei Zhang. (2021) Discovery of indole-3-butyric acid derivatives as potent histone deacetylase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 425-436.
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Lei Zhang, Jian Zhang, Qixiao Jiang, Li Zhang & Weiguo Song. (2018) Zinc binding groups for histone deacetylase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 714-721.
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Articles from other publishers (20)

Yuan-Yuan Guo, Jing-Yi Zhang, Jin-Feng Sun, Peng Nie & Hua Gao. (2023) Synthesis and application of small molecules approved for the treatment of lymphoma. European Journal of Medicinal Chemistry 261, pages 115835.
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Phuong Hong Nguyen, Bui Thi Buu Hue, Minh Quan Pham, Tran Phuong Hoa, Quang De Tran, Hosun Jung, Le Trong Hieu, Nguyen Cuong Quoc, Hong Vinh Quang, Nguyen Phu Quy, Hye Jin Yoo & Su-Geun Yang. (2023) Novel histone deacetylase 6 inhibitors using benzimidazole as caps for cancer treatment. New Journal of Chemistry 47:16, pages 7622-7631.
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Hong Phuong Nguyen, Quang De Tran, Cuong Quoc Nguyen, Tran Phuong Hoa, Tran Duy Binh, Huynh Nhu Thao, Bui Thi Buu Hue, Nguyen Trong Tuan, Quang Le Dang, Nguyen Quoc Chau Thanh, Nguyen Van Ky, Minh Quan Pham & Su-Geun Yang. (2022) Anti-multiple myeloma potential of resynthesized belinostat derivatives: an experimental study on cytotoxic activity, drug combination, and docking studies. RSC Advances 12:34, pages 22108-22118.
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Qian Hui, Lihui Zhang, Jinhong Feng & Lei Zhang. (2022) Discovery of 2-Phenylquinoline-4-Carboxylic Acid Derivatives as Novel Histone Deacetylase Inhibitors. Frontiers in Chemistry 10.
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Xiangyu Ma, Mengjie Zhao, Zhuo-Xun Wu, Jingfang Yao, Lei Zhang, Jinhong Wang, Zhenbo Hu, Liuya Wei & Zhe-Sheng Chen. (2022) The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells. Frontiers in Oncology 12.
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Hue Thi Buu Bui, Phuong Hong Nguyen, Quan Minh Pham, Hoa Phuong Tran, De Quang Tran, Hosun Jung, Quang Vinh Hong, Quoc Cuong Nguyen, Quy Phu Nguyen, Hieu Trong Le & Su-Geun Yang. (2022) Target Design of Novel Histone Deacetylase 6 Selective Inhibitors with 2-Mercaptoquinazolinone as the Cap Moiety. Molecules 27:7, pages 2204.
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Piyush Gediya, Palak K. Parikh, Vivek K. Vyas & Manjunath D. Ghate. (2021) Histone deacetylase 2: A potential therapeutic target for cancer and neurodegenerative disorders. European Journal of Medicinal Chemistry 216, pages 113332.
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Wenli Fan, Lihui Zhang, Qixao Jiang, Weiguo Song, Fang Yan & Lei Zhang. (2020) Histone deacetylase inhibitor based prodrugs. European Journal of Medicinal Chemistry 203, pages 112628.
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Nguyễn Cường Quốc, Trần Quang Đệ, Bùi Thị Bửu Huê, Nguyễn Trọng Tuân, Lê Thị Bạch, Hà Thị Kim Quy, Huỳnh Như Thảo, Võ Thị Như Ý, Nguyễn Hồng Thi, Trần Nguyễn Gia Huy, Huỳnh Thanh Ngân, Đặng Thị Thu Thảo & Nguyễn Thị Huỳnh Trang. (2020) hiết kế, tổng hợp và đánh giá khả năng ức chế enzyme histone deacetylase (HDAC) in silico của một số dẫn xuất tương tự belinostat. Can Tho University Journal of Science 56(NaturalScience), pages 1.
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Jie-Huan Zhang, Madhusoodanan Mottamal, Hai-Shan Jin, Shanchun Guo, Yan Gu, Guangdi Wang & Li-Ming Zhao. (2019) Design, synthesis and evaluation of belinostat analogs as histone deacetylase inhibitors. Future Medicinal Chemistry 11:21, pages 2765-2778.
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Lihui Zhang, Xiaoyang Li, Yiming Chen, Minghui Wan, Qixiao Jiang, Li Zhang, C. James Chou, Weiguo Song & Lei Zhang. (2019) Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor. Frontiers in Pharmacology 10.
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Xiaopeng Peng, Guochao Liao, Pinghua Sun, Zhiqiang Yu & Jianjun Chen. (2019) An Overview of HDAC Inhibitors and their Synthetic Routes. Current Topics in Medicinal Chemistry 19:12, pages 1005-1040.
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Lihui Zhang, Yiming Chen, Qixiao Jiang, Weiguo Song & Lei Zhang. (2019) Therapeutic potential of selective histone deacetylase 3 inhibition. European Journal of Medicinal Chemistry 162, pages 534-542.
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Larry Yet. 2018. Privileged Structures in Drug Discovery. Privileged Structures in Drug Discovery 435 480 .
Lei Zhang, Li Zhang, Jiang Bian, Qixiao Jiang, Jianjun Gao & Weiguo Song. (2018) Structural modification of histone deacetylase inhibitors with a phenylglycine scaffold. Anti-Cancer Drugs 29:2, pages 145-156.
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Xuefei Bao, Dake Song, Xuejun Qiao, Xuan Zhao & Guoliang Chen. (2016) The Development of an Effective Synthetic Route of Belinostat. Organic Process Research & Development 20:8, pages 1482-1488.
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Andrew C. Flick, Hong X. Ding, Carolyn A. Leverett, Robert E. KyneJr.Jr., Kevin K.-C. Liu, Sarah J. Fink & Christopher J. O’Donnell. (2016) Synthetic approaches to the 2014 new drugs. Bioorganic & Medicinal Chemistry 24:9, pages 1937-1980.
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Pavlo A. Sokolyuk, Ivan S. Kondratov, Olexiy V. Gavrylenko & Andrey A. Tolmachov. (2015) Synthesis of diverse pyrazole-4-sulfonyl chlorides starting from 2-(benzylthio)malonaldehyde. Molecular Diversity 20:1, pages 1-7.
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Jiang Bian, Yepeng luan, Chunbo Wang & Lei Zhang. (2016) Discovery of N-hydroxy-4-(1H-indol-3-yl)butanamide as a histone deacetylase inhibitor. Drug Discoveries & Therapeutics 10:3, pages 163-166.
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Lei Yang, Xiaowen Xue & Yihua Zhang. (2010) ChemInform Abstract: Simple and Efficient Synthesis of Belinostat.. ChemInform 42:4.
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