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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 44, 2014 - Issue 9
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Original Articles

Paal–Knorr Pyrrole Synthesis in Water

Dilek Akbaşlar Department of Chemistry, Art and Science Faculty, Çukurova University, Adana, Turkey
,
Onur Demirkol Department of Chemistry, Art and Science Faculty, Çukurova University, Adana, Turkey
&
Sultan Giray Department of Chemistry, Art and Science Faculty, Çukurova University, Adana, TurkeyCorrespondence[email protected]
Pages 1323-1332 | Received 12 Sep 2013, Published online: 28 Mar 2014

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Shakeel Alvi, Ahmad Hasan & Rashid Ali. (2023) The Paal–Knorr Pyrroles Synthesis: A Green Perspective. Polycyclic Aromatic Compounds 0:0, pages 1-18.
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Asha D. Jangale & Dipak S. Dalal. (2017) Green synthetic approaches for biologically relevant organic compounds. Synthetic Communications 47:23, pages 2139-2173.
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Burcu Bozdoğan, Mehmet Erşatır, Onur Demirkol, Dilek Akbaşlar & E. Sultan Giray. (2017) Simple and efficient synthesis of N-alkyl and N-aryl succinimides in hot water. Synthetic Communications 47:3, pages 217-223.
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Articles from other publishers (25)

Luiz H. Dapper, Kethelyn M. da Rosa, Viviane T. Mena, Rodrigo O. M. A. de Souza, Felipe L. N. da Silva, Thiago Anjos, Filipe Penteado & Eder J. Lenardão. (2024) Ammonium niobium oxalate (ANO) as an efficient catalyst in the Paal–Knorr synthesis of N -substituted pyrroles . RSC Sustainability 2:2, pages 521-527.
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Natalia V. Obruchnikova & Oleg A. Rakitin. (2023) 4-(2,5-Dimethyl-1H-pyrrol-1-yl)-1,2,5-oxadiazol-3-amine. Molbank 2023:3, pages M1700.
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Liwei Ni, Shiying Yang, Wenze Qiu, Jialei Jin, Qiyue Xu & Shuliang Ye. (2023) Mechanism study of the N-butoxycarbonyl-2,5-dimethylpyrrole synthesis reaction based on in-situ FTIR monitoring. Vibrational Spectroscopy 127, pages 103558.
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Ahmed YOUNİS & Ahmed OSMAN. (2023) Solvent-free Organic Reaction Techniques as an Approach for Green Chemistry. Journal of the Turkish Chemical Society Section A: Chemistry 10:2, pages 549-576.
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R. Bernadett Vlocskó, Guoshu Xie & Béla Török. (2023) Green Synthesis of Aromatic Nitrogen-Containing Heterocycles by Catalytic and Non-Traditional Activation Methods. Molecules 28:10, pages 4153.
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Sambasivarao Kotha & Deepshikha Singh. (2023) Synthesis of pyrrole derivatives via ring closing metathesis, Clauson‐Kaas reaction and Paal‐Knorr condensation as key steps. Journal of Molecular Structure 1275, pages 134600.
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Tao Shi, Gaofeng Yin, Xiaodong Wang, Yongxia Xiong, Yan Peng, Shuang Li, Yaofu Zeng & Zhen Wang. (2023) Recent advances in the syntheses of pyrroles. Green Synthesis and Catalysis 4:1, pages 20-34.
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Christian Schäfer, Hyejin Cho, Bernadett Vlocskó, Guoshu Xie & Béla Török. (2022) Recent Advances in the Green Synthesis of Heterocycles: From Building Blocks to Biologically Active Compounds. Current Organic Synthesis 19:3, pages 426-462.
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Chien-Chi Wu, Ram Ambre, Meng-Hsuan Lee & Jiun-Jie Shie. (2022) Flexible Construction Approach to the Synthesis of 1,5-Substituted Pyrrole-3-carbaldehydes from 5-Bromo-1,2,3-triazine. Organic Letters 24:15, pages 2889-2893.
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Majid M. Heravi & Vahideh Zadsirjan. 2022. 1 60 .
Christian Schäfer, Hyejin Cho & Béla Török. 2022. Green Chemistry in Drug Discovery. Green Chemistry in Drug Discovery 3 33 .
Shakeel Alvi & Rashid Ali. (2021) An expeditious and highly efficient synthesis of substituted pyrroles using a low melting deep eutectic mixture. Organic & Biomolecular Chemistry 19:44, pages 9732-9745.
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Satish Chandra Philkhana, Fatimat O. Badmus, Isaac C. Dos Reis & Rendy Kartika. (2021) Recent Advancements in Pyrrole Synthesis. Synthesis 53:09, pages 1531-1555.
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Robert H.E. Schirmacher, Daniel Rösch & Franziska Thomas. (2021) Hexafluoroisopropanol as solvent and promotor in the Paal-Knorr synthesis of N-substituted diaryl pyrroles. Tetrahedron 83, pages 131985.
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Jasper J. A. Lozeman, Tobias Elsbecker, Sylvie Bohnenn, Hans L. de Boer, Max Krakers, Guido Mul, Albert van den Berg & Mathieu Odijk. (2020) Modular microreactor with integrated reflection element for online reaction monitoring using infrared spectroscopy. Lab on a Chip 20:22, pages 4166-4174.
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Duc Dau Xuan. (2020) Recent Progress in the Synthesis of Pyrroles. Current Organic Chemistry 24:6, pages 622-657.
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Xinglei Zhang, Miaorong Pei, Debo Wu, Shuiping Yang & Zhanggao Le. (2019) Real-time monitoring of the reaction between aniline and acetonylacetone using extractive electorspray ionization tandem mass spectrometry. Scientific Reports 9:1.
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Ebrahim Saeedian Moghadam, Farhad Saravani, Seyednasser Ostad, Shohreh Tavajohi, Morteza Pirali Hamedani & Mohsen Amini. (2018) Design, synthesis and cytotoxicity evaluation of indibulin analogs. Heterocyclic Communications 24:4, pages 211-217.
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Kioumars Aghapoor, Farshid Mohsenzadeh, Hossein Reza Darabi & Saeed Rastgar. (2018) Microwave-induced calcium(II) chloride-catalyzed Paal–Knorr pyrrole synthesis: a safe, expeditious, and sustainable protocol. Research on Chemical Intermediates 44:7, pages 4063-4072.
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Chun-yan Chen, Xiao-ya Guo, Guang-qiang Lu, Christian Marcus Pedersen, Yan Qiao, Xiang-lin Hou & Ying-xiong Wang. (2017) Graphene oxide: a novel acid catalyst for the synthesis of 2,5-dimethyl-N-phenyl pyrrole by the Paal–Knorr condensation. New Carbon Materials 32:2, pages 160-167.
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Xiaobing Yang, Yang Wang, Fangzhong Hu, Xiaoli Kan, Chiming Yang, Jiahui Liu, Pei Liu & Qichun Zhang. (2016) Base-promoted intramolecular cyclization of N-alkyl, N-propargylic β-enaminones for the synthesis of polysubstituted pyrroles. RSC Advances 6:72, pages 68454-68459.
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Sheenu Abbat, Devendra Dhaked, Minhajul Arfeen & Prasad V. Bharatam. (2015) Mechanism of the Paal–Knorr reaction: the importance of water mediated hemialcohol pathway. RSC Advances 5:107, pages 88353-88366.
Crossref
Peng Liu, Jian-Wu Hao, Li-Ping Mo & Zhan-Hui Zhang. (2015) Recent advances in the application of deep eutectic solvents as sustainable media as well as catalysts in organic reactions. RSC Advances 5:60, pages 48675-48704.
Crossref
Dilek Akbaslar, Onur Demirkol & Sultan Giray. (2014) ChemInform Abstract: Paal—Knorr Pyrrole Synthesis in Water.. ChemInform 45:38.
Crossref
Abhijeet Srivastava, Gaurav Shukla, Anugula Nagaraju, Girijesh Kumar Verma, Keshav Raghuvanshi, Raymond C. F. Jones & Maya Shankar Singh. (2014) In(OTf) 3 -catalysed one-pot versatile pyrrole synthesis through domino annulation of α-oxoketene-N,S-acetals with nitroolefins . Org. Biomol. Chem. 12:29, pages 5484-5491.
Crossref

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