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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 16
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Original Articles

An efficient multicomponent synthesis and in vitro anticancer activity of dihydropyranochromene and chromenopyrimidine-2,5-diones

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Pages 2046-2060 | Received 20 Mar 2018, Published online: 11 Jul 2018

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Najla A. Alshaye & Magdy A. Ibrahim. (2023) Design, synthesis, characterization, and antimicrobial evaluation of the novel 2-heteroarylchromeno[2,3-d]pyrimidines. Synthetic Communications 53:10, pages 744-754.
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Articles from other publishers (26)

Rasha Z. Batran, Eman Y. Ahmed, Eman S. Nossier, Hanem M. Awad & Nehad A. Abdel Latif. (2024) Anticancer activity of new triazolopyrimidine linked coumarin and quinolone hybrids: Synthesis, molecular modeling, TrkA, PI3K/AKT and EGFR inhibition. Journal of Molecular Structure 1305, pages 137790.
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Vinita Yadav, Ajay Thakur, Ruchi Bharti, Monika Verma & Renu Sharma. (2024) Recent Advancement in Multicomponent Synthesis of Fused Coumarin Derivatives. Current Organic Synthesis 21:3, pages 303-330.
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Kumari Kajal, Ruchi Shakya, Mohd Rashid, Vaibhav Nigam, Balak Das Kurmi, Ghanshyam Das Gupta & Preeti Patel. (2024) Recent green chemistry approaches for pyrimidine derivatives as a potential anti-cancer agent: An overview (2013–2023). Sustainable Chemistry and Pharmacy 37, pages 101374.
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Pedro S. Beck, Arthur G. Leitão, Yasmin B. Santana, José R. Correa, Carime V. S. Rodrigues, Daniel F. S. Machado, Guilherme D. R. Matos, Luciana M. Ramos, Claudia C. Gatto, Sarah C. C. Oliveira, Carlos K. Z. Andrade & Brenno A. D. Neto. (2024) Revisiting Biginelli-like reactions: solvent effects, mechanisms, biological applications and correction of several literature reports. Organic & Biomolecular Chemistry.
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Manisha Chadha, Ankita Garg, Aman Bhalla & Shiwani Berry. (2024) Green methods mediated synthesis of chromene derivatives using magnetic nanoparticles as heterogeneous and reusable nanocatalyst: A review. Tetrahedron 150, pages 133741.
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Ibrahim O. Althobaiti, Mjd Saleh Morezeq Alserhani, Wael A. A. Arafa, Amira A. Ghoneim, Modather F. Hussein, Hamada Mohamed Ibrahim & Asmaa K. Mourad. (2023) Efficient Protocol for Novel Hybrid Pyrimidines Synthesis: Antiproliferative Activity, DFT Analyses, and Molecular Docking Studies. ACS Omega 8:49, pages 47239-47253.
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Sizwe J. Zamisa, Adesola A. Adeleke, Nikita Devnarain, Mahasin Abdel Rhman, Peter M. O. Owira & Bernard Omondi. (2023) The link between relative stability constant of DNA- and BSA-chromenopyrimidine complexes and cytotoxicity towards human breast cancer cells (MCF-7). RSC Advances 13:32, pages 21820-21837.
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Farzaneh Ghobakhloo, Davood Azarifar & Masoud Mohammadi. (2023) Macrocyclic pseudo crown-ether- manganese (II) complex coated on nanomagnetic LDH- catalyzed Biginelli annulation reactions. Journal of Physics and Chemistry of Solids 175, pages 111222.
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K. Fabitha, C. G. Arya, Munugala Chandrakanth & Janardhan Banothu. (2022) Green chemistry approach: sodium fluoride-catalyzed highly efficient microwave irradiation-assisted synthesis of substituted chromene derivatives in aqueous medium. Research on Chemical Intermediates 49:3, pages 997-1014.
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Kshipra S. Karnik, Aniket P. Sarkate, Shailee V. Tiwari, Rajaram Azad & Pravin S. Wakte. (2022) Design, synthesis, biological evaluation and in silico studies of EGFR inhibitors based on 4-oxo-chromane scaffold targeting resistance in non-small cell lung cancer (NSCLC). Medicinal Chemistry Research 31:9, pages 1500-1516.
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Pooja Garg & Sabbasani Rajasekhara Reddy. (2022) Biomass‐derived Sugar Ionic Liquid as a Sustainable Organocatalyst: An Efficient Synthesis of Functionalized Dihydropyrano Coumarins. Asian Journal of Organic Chemistry 11:9.
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Anjali Rawat & A. Vijaya Bhaskar Reddy. (2022) Recent advances on anticancer activity of coumarin derivatives. European Journal of Medicinal Chemistry Reports 5, pages 100038.
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Ravindra Haribhau Waghchaure, Bapu Sonu Jagdale, Prashant Bhimrao Koli & Vishnu Ashok Adole. (2022) Nano 5% Fe–ZnO: A highly efficient and recyclable heterogeneous solid nano catalyst for the Biginelli reaction. Journal of the Indian Chemical Society 99:6, pages 100468.
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Khaled M. Elattar, Ayman Y. El-Khateeb & Sahar E. Hamed. (2022) Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs. RSC Medicinal Chemistry 13:5, pages 522-567.
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Farzaneh Ghobakhloo, Davood Azarifar, Masoud Mohammadi, Hassan Keypour & Hamid Zeynali. (2022) Copper(II) Schiff-Base Complex Modified UiO-66-NH 2 (Zr) Metal–Organic Framework Catalysts for Knoevenagel Condensation–Michael Addition–Cyclization Reactions . Inorganic Chemistry 61:12, pages 4825-4841.
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Biplob Borah, Kartikey Dhar Dwivedi & L. Raju Chowhan. (2021) 4‐Hydroxycoumarin: A Versatile Substrate for Transition‐metal‐free Multicomponent Synthesis of Bioactive Heterocycles. Asian Journal of Organic Chemistry 10:12, pages 3101-3126.
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Ueveton Pimentel da Silva, Bianca Lana de Sousa, Bruno Wesley Ferreira, Robert Weingart Barreto, Giovanni Wilson Amarante, Rodolfo Rodrigues da Silva, Boniek Gontijo Vaz & Eduardo Vinícius Vieira Varejão. (2021) Daylight LED promotes photochemical ring contraction of 2-amine-4H-pyran-3-carbonitriles with consequent loss of their antifungal activity. Photochemical & Photobiological Sciences 20:10, pages 1309-1321.
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Li-Peng Shan, Li-Hua Hu, Qi Zhao, Li-Ning Zhang, Lei Liu, Jiong Chen & Jian-Ping Chen. (2021) Difference in medication pattern potentially enhances antiviral efficiency of a novel amino-fluorophenyl compound on WSS risk in shrimp seedling culture. Aquaculture 539, pages 736670.
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Aniket P. Sarkate, Vidya S. Dofe, Shailee V. Tiwari, Deepak K. Lokwani, Kshipra S. Karnik, Darshana D. Kamble, Mujahed H.S.H. Ansari, Suneel Dodamani, Sunil S. Jalalpure, Jaiprakash N. Sangshetti, Rajaram Azad, Prasad V.L.S. Burra & Shashikant V. Bhandari. (2021) One pot synthesis, in silico study and evaluation of some novel flavonoids as potent topoisomerase II inhibitors. Bioorganic & Medicinal Chemistry Letters 40, pages 127916.
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Nitin M. Thorat, Aniket P. Sarkate, Deepak K. Lokwani, Shailee V. Tiwari, Rajaram Azad & Shankar R. Thopate. (2020) N-Benzylation of 6-aminoflavone by reductive amination and efficient access to some novel anticancer agents via topoisomerase II inhibition. Molecular Diversity 25:2, pages 937-948.
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Komal Chandrakar, Jeevan Lal Patel, S. P. Mahapatra & Santhosh Penta. (2020) Recent Advances in On-Water Multicomponent Synthesis of Coumarin Derivatives. Current Organic Chemistry 24:22, pages 2601-2611.
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Clementina M.M. Santos & Artur M.S. Silva. 2020. 533 595 .
Manisha R. Bhosle, Supriya A. Joshi, Giribala M. Bondle & Jaiprakash N. Sangshetti. (2019) Supramolecular biomimetic catalysis by β-cyclodextrin for the synthesis of new antimicrobial chromeno[4,3-b]quinolin-isonicotinamides in water. Research on Chemical Intermediates 46:1, pages 737-753.
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Nader Noroozi Pesyan, Ghasem Rezanejade Bardajee, Elmira Kashani, Marzieh Mohammadi & Hana Batmani. (2019) Ni(II)-Schiff base/SBA-15: a nanostructure and reusable catalyst for one-pot three-component green synthesis of 3,4-dihydropyrano[3,2-c]chromene derivatives. Research on Chemical Intermediates 46:1, pages 347-367.
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Manisha R. Bhosle, Supriya A. Joshi & Giribala M. Bondle. (2019) An efficient contemporary multicomponent synthesis for the facile access to coumarin‐fused new thiazolyl chromeno[4,3‐ b ]quinolones in aqueous micellar medium . Journal of Heterocyclic Chemistry 57:1, pages 456-468.
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Sergey I. Filimonov, Zhanna V. Chirkova, Mariya V. Kabanova, Elena S. Makarova, Anton A. Shetnev, Valeria A. Panova & Kyrill Yu. Suponitsky. (2019) A Condensation of Biginelli Products with 1,3‐Benzenediols: a Facile Access to Diastereomerically Pure Hexahydro‐5 H ‐chromeno[4,3‐ d ]pyrimidin‐5‐ones . ChemistrySelect 4:33, pages 9550-9555.
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