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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 50, 2020 - Issue 2
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Synthetic Communications Reviews

Facile and expedient synthesis and anti-proliferative activity of diversely pyrrolones bearing 1,3-diphenylpyrazole moiety

Sayed K. RamadanChemistry Department, Faculty of Science, Ain Shams University, Abassia, Cairo, EgyptCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0003-2743-6544
ORCID Icon,
Safaa S. ShabanChemistry Department, Faculty of Science, Ain Shams University, Abassia, Cairo, Egypt
&
Ahmed I. HashemChemistry Department, Faculty of Science, Ain Shams University, Abassia, Cairo, EgyptORCID Iconhttp://orcid.org/0000-0002-7524-9279
ORCID Icon
Pages 185-196 | Received 10 Oct 2019, Published online: 18 Nov 2019

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Youssef M. Youssef, Mohammad E. Azab, Galal A. Elsayed, Amira A. El-Sayed & Eman A. E. El-Helw. (2023) Synthesis and Antiproliferative Screening of Some Heterocycles Derived from 4-((5-Chloro-3-Methyl-1-Phenyl-1H-Pyrazol-4-yl)Methylene)-2-Phenyloxazol-5(4H)-One. Polycyclic Aromatic Compounds 43:8, pages 7152-7163.
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Sayed K. Ramadan, Hisham S. M. Abd-Rabboh, Nourhan M. Gad, Wael S. I. Abou-Elmagd & David S. A. Haneen. (2023) Synthesis and Characterization of Some Chitosan-Quinoline Nanocomposites as Potential Insecticidal Agents. Polycyclic Aromatic Compounds 43:8, pages 7013-7026.
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Youssef M. Youssef, Mohammad E. Azab, Galal A. Elsayed, Amira A. El-Sayed, Aya I. Hassaballah & Eman A. E. El-Helw. (2023) Synthesis and antioxidant activity of some pyrazole-based heterocycles using a 2(3H)-furanone building block. Synthetic Communications 53:5, pages 402-413.
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Sayed K. Ramadan, Nasser A. Ibrahim, Sarah A. El-Kaed & Eman A. E. El-Helw. (2021) New potential fungicides pyrazole-based heterocycles derived from 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl) acryloyl isothiocyanate. Journal of Sulfur Chemistry 42:5, pages 529-546.
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Mohamed M Kaddah, Abdelgawad A. Fahmi, Mustafa M. Kamel, Sayed K. Ramadan & Sameh A. Rizk. (2021) Synthesis, characterization, computational chemical studies and antiproliferative activity of some heterocyclic systems derived from 3-(3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-2H-chromen-2-one. Synthetic Communications 51:12, pages 1798-1813.
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Azza A. El-Badawy, Amna S. Elgubbi & Eman A. E. El-Helw. (2021) Acryloyl isothiocyanate skeleton as a precursor for synthesis of some novel pyrimidine, triazole, triazepine, thiadiazolopyrimidine and acylthiourea derivatives as antioxidant agents. Journal of Sulfur Chemistry 42:3, pages 295-307.
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Nourhan M. Gad, Wael S. I. Abou-Elmagd, David S. A. Haneen & Sayed K. Ramadan. (2021) Reactivity of 5-phenyl-3-[(2-chloroquinolin-3-yl)methylene] furan-2(3H)-one towards hydrazine and benzylamine: A comparative study. Synthetic Communications 51:9, pages 1384-1397.
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Sayed K. Ramadan, Ahmed K. El-Ziaty & Eman A. E. El-Helw. (2021) Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1H-pyrazol-4-yl)-2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)propenonitrile. Synthetic Communications 51:8, pages 1272-1283.
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Abeer M. El-Naggar & Sayed K. Ramadan. (2020) Efficient synthesis of some pyrimidine and thiazolidine derivatives bearing quinoline scaffold under microwave irradiation. Synthetic Communications 50:14, pages 2188-2198.
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Hanan A. Sallam, Amna S. Elgubbi & Eman A. E. El-Helw. (2020) Synthesis and antioxidant screening of new 2-cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl amide derivatives and some pyrazole-based heterocycles. Synthetic Communications 50:13, pages 2066-2077.
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Karema N. M. Halim, Sayed K. Ramadan, Sameh A. Rizk & Maher A. El-Hashash. (2020) Synthesis, DFT study, molecular docking and insecticidal evaluation of some pyrazole-based tetrahydropyrimidine derivatives. Synthetic Communications 50:8, pages 1159-1175.
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Eman A. E. El-Helw & Ahmed I. Hashem. (2020) Synthesis and antitumor activity evaluation of some pyrrolone and pyridazinone heterocycles derived from 3-((2-oxo-5-(p-tolyl)furan-3(2H)-ylidene)methyl)quinolin-2(1H)-one. Synthetic Communications 50:7, pages 1046-1055.
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C.Geetha Priya, B.R. Venkatraman, N. Elangovan, M.Dhinesh Kumar, T. Arulmozhi, S. Sowrirajan, Mohammad Shahidul Islam & Jebasingh Bhagavathsingh. (2023) Absorption studies on serotonin neurotransmitter with the platinum metal cluster using the gas phase and different solvents, topological and non-covalent interaction: A DFT approach. Chemical Physics Impact 7, pages 100295.
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Jamelah S. Al-Otaibi, Y. Sheena Mary, Y. Shyma Mary, Renjith Thomas & Renyer Alves Costa. (2023) DFT Investigations on the Interactions Between Pyrimidine Derivatives and Ag/Au/Cu Metal Clusters: Solvation Effects and Reactivity Analysis. Journal of Cluster Science 34:6, pages 2847-2858.
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Mehmet Abdullah ALAGÖZ, İnci Selin DOĞAN, Sıla SENER & Zeynep ÖZDEMİR. (2022) Synthesis, Molecular Docking and Molecular Dynamics Simulation Studies of Some Pyridazinone Derivatives as Lipase Inhibitors. Cumhuriyet Science Journal 43:3, pages 391-397.
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Sayed K. Ramadan, Doaa R. Abdel Haleem, Hisham S. M. Abd-Rabboh, Nourhan M. Gad, Wael S. I. Abou-Elmagd & David S. A. Haneen. (2022) Synthesis, SAR studies, and insecticidal activities of certain N-heterocycles derived from 3-((2-chloroquinolin-3-yl)methylene)-5-phenylfuran-2(3 H )-one against Culex pipiens L. larvae . RSC Advances 12:22, pages 13628-13638.
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Sayed K. Ramadan & Sameh A. Rizk. (2021) Synthesis, density functional theory, and cytotoxic activity of some heterocyclic systems derived from 3-(3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-2H-chromen-2-one. Journal of the Iranian Chemical Society 19:1, pages 187-201.
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Amit Kumar Jana, Jyotsana Singh, Asha Ganesher, Amit Kumar, Arpita Banerjee, Deepak Kumar, Sarvesh Kumar Verma, Ashok Kumar Sharma, Rabi Sankar Bhatta, Rituraj Konwar & Gautam Panda. (2021) Tyrosine-Derived Novel Benzoxazine Active in a Rat Syngenic Mammary Tumor Model of Breast Cancer. Journal of Medicinal Chemistry 64:21, pages 16293-16316.
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Arif Mermer, Turgut Keles & Yakup Sirin. (2021) Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review. Bioorganic Chemistry 114, pages 105076.
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Eman A. E. El‐Helw, Alaa R. I. Morsy & Ahmed I. Hashem. (2021) Evaluation of some new heterocycles bearing 2‐oxoquinolyl moiety as immunomodulator against highly pathogenic avian influenza virus ( H 5 N 8 ) . Journal of Heterocyclic Chemistry 58:4, pages 1003-1014.
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Karema N. M. Halim, Sameh A. Rizk, Maher A. El‐Hashash & Sayed K. Ramadan. (2020) Straightforward synthesis, antiproliferative screening, and density functional theory study of some pyrazolylpyrimidine derivatives. Journal of Heterocyclic Chemistry 58:2, pages 636-645.
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Sayed K. Ramadan, Ahmed K. El‐Ziaty & Rania S. Ali. (2020) Synthesis, antiproliferative activity, and molecular docking of some N ‐heterocycles bearing a pyrazole scaffold against liver and breast tumors . Journal of Heterocyclic Chemistry 58:1, pages 290-304.
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Sayed K. Ramadan, Karema N. M. Halim, Sameh A. Rizk & Maher A. El-Hashash. (2020) Cytotoxic activity and density functional theory studies of some 1,3-diphenylpyrazolyltetrahydropyrimidine derivatives. Journal of the Iranian Chemical Society 17:7, pages 1575-1589.
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Eman A. E. El-Helw, Marwa M. Gado & Ahmed K. El-Ziaty. (2020) Synthesis and anti-rotavirus activity of some nitrogen heterocycles integrated with pyrazole scaffold. Journal of the Iranian Chemical Society 17:6, pages 1479-1492.
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Assem Barakat, Saied M. Soliman, Matti Haukka, Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, M. Ali & Mohammed Rafi Shaik. (2020) One-Pot Synthesis, X-ray Single Crystal and Molecular Insight of Enaminone-Based β-Morpholino-/N-Methylpiperazinyl-/Pyrrolidinylpropiophenone. Crystals 10:4, pages 282.
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