Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 22
Submit an article Journal homepage
142
Views
21
CrossRef citations to date
0
Altmetric
Original Articles

Synthesis of N-(Tert-butoxycarbonyl)-3-(4-thiazoIyl)-L-alanine

Chi-Nung Hsiao Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
,
M. Robert Leanna Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
,
Lakshmi Bhagavatula Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
,
Edwin De Lara Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
,
Thomas M. Zydowsky Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
,
Bruce W. Horrom Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
&
Howard E. Morton Abbott Laboratories, Dept. 45L/AP10, Process Chemistry Pharmaceutical Products Research Division, Abbott Park, Illinois, 60064
 show all
Pages 3507-3517 | Received 14 Oct 1990, Published online: 24 Oct 2006

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Pulla Reddy Singam, CurtW. Bradshaw, JeromeA. Menzia, B.A. Narayanan, ToddW. Rockway, Noel Welch & Jien-HehJ. Tien. (1996) An Efficient Process for the Synthesis of Renin Inhibitor, ABT-517. Synthetic Communications 26:14, pages 2751-2756.
Read now

Articles from other publishers (20)

Naotake KobayashiNorihito SatoKatsuji SugitaTsuyoshi Kihara, Katsumi KoikeTamio SugawaraYukio TadaTakayoshi Yoshikawa. (2021) Synthesis and Evaluation of <i>in Vivo</i> Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4<i>S</i>,5<i>S</i>)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide. Chemical and Pharmaceutical Bulletin 69:4, pages 314-324.
Crossref
Naotake Kobayashi, Norihito Sato, Katsuji Sugita, Kouji Takahashi, Tamio Sugawara, Yukio Tada & Takayoshi Yoshikawa. (2019) Synthesis and evaluation of in vivo anti‐hypothermic effect of all stereoisomers of the thyrotropin‐releasing hormone mimetic: Rovatirelin Hydrate. Journal of Peptide Science 25:12.
Crossref
David Peter & Reinhard Brückner. (2018) Syntheses of a Pair of Simplified Model Compounds of the Dihydroxycyclopentenone Core of the Kodaistatins A-D. European Journal of Organic Chemistry 2018:45, pages 6256-6273.
Crossref
Naotake Kobayashi, Norihito Sato, Yuko Fujimura, Tsuyoshi Kihara, Katsuji Sugita, Kouji Takahashi, Katsumi Koike, Tamio Sugawara, Yukio Tada, Hiroshi Nakai & Takayoshi Yoshikawa. (2018) Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{ N -[(4 S ,5 S )-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)- l -alanyl}-(2 R )-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate) . ACS Omega 3:10, pages 13647-13666.
Crossref
David Peter & Reinhard Brückner. (2017) A New Approach to Models of the 4,5‐Dihydroxycyclopentenone Core of the Kodaistatins A–D: Elucidation of the Diol Configuration in Kodaistatin A. Chemistry – A European Journal 23:50, pages 12104-12109.
Crossref
Xuesong Luo, Gui Chen, Lin He & Xueliang Huang. (2016) Amination of Diazocarbonyl Compounds: N–H Insertion under Metal-Free Conditions. The Journal of Organic Chemistry 81:7, pages 2943-2949.
Crossref
Antoine Jobin-Des Lauriers & Claude Y. Legault. (2015) Iodine(III)-Mediated Oxidative Hydrolysis of Haloalkenes: Access to α-Halo Ketones by a Release-and-Catch Mechanism. Organic Letters 18:1, pages 108-111.
Crossref
Angela Gonzalez-de-CastroJianliang Xiao. (2015) Green and Efficient: Iron-Catalyzed Selective Oxidation of Olefins to Carbonyls with O 2 . Journal of the American Chemical Society 137:25, pages 8206-8218.
Crossref
Michael P. Curtis, Wesley Dwight, John Pratt, Marlon Cowart, Timothy A. Esbenshade, Kathy M. Krueger, Gerard B. Fox, Jia Bao Pan, Thomas G. Pagano, Arthur A. Hancock, Ramin Faghih & Youssef L. Bennani. (2004) D‐Amino Acid Homopiperazine Amides: Discovery of A‐320436, a Potent and Selective Non‐Imidazole Histamine H 3 ‐Receptor Antagonist . Archiv der Pharmazie 337:4, pages 219-229.
Crossref
Michael P. VanBrunt, Reuben O. Ambenge & Steven M. Weinreb. (2003) A Mild, Convenient, and Inexpensive Procedure for Conversion of Vinyl Halides to α-Haloketones. The Journal of Organic Chemistry 68:8, pages 3323-3326.
Crossref
A. Liese, K. Seelbach & C. WandreyAndreas Liese, Karsten Seelbach, Arne Buchholz & Jürgen Haberland. 2000. Industrial Biotransformations. Industrial Biotransformations 94 396 .
Bruno Simoneau, Pierre Lavallée, Murray Bailey, Jean-Simon Duceppe, Chantal Grand-Maître, Louis Grenier, William W Ogilvie, Marc-André Poupart & Bounkham Thavonekham. (2000) Stereoselective synthesis of renin inhibitor BILA 2157 BS. Canadian Journal of Chemistry 78:6, pages 739-748.
Crossref
Patrik Kolar, Andrej Petrič & Miha Tišler. (2009) Heteroarylalanines. Journal of Heterocyclic Chemistry 34:4, pages 1067-1098.
Crossref
. 1996. Comprehensive Heterocyclic Chemistry II. Comprehensive Heterocyclic Chemistry II 817 932 .
Alessandro Dondoni & Pedro Merino. 1996. Comprehensive Heterocyclic Chemistry II. Comprehensive Heterocyclic Chemistry II 373 474 .
B. Imperiali, R. Sinha Roy, G. K. Walkup & L. Wang. 1996. Molecular Design and Bioorganic Catalysis. Molecular Design and Bioorganic Catalysis 35 52 .
Saul H. Rosenberg, Kenneth P. Spina, Herman Stein, Jerome Cohen, William R. Baker & Hollis D. Kleinert. (1994) Renin inhibitors: C-terminal oxetanes as potent transition-state mimics. Bioorganic & Medicinal Chemistry 2:9, pages 927-937.
Crossref
Hidemi Yoda, Yoshiaki Nakagami & Kinihiko Takabe. (1994) Diastereoselective reactions of grignard reagents with chiral amino lactols derived firom L-aspartic acid. Tetrahedron: Asymmetry 5:2, pages 169-172.
Crossref
Howard E. Morton & M.Robert Leanna. (1993) Synthesis of α-halomethyl ketones: Oxidative hydrolysis of vinyl halides. Tetrahedron Letters 34:28, pages 4481-4484.
Crossref
C.‐N. HSIAO, M. R. LEANNA, L. BHAGAVATULA, E. DE LARA, T. M. ZYDOWSKY, B. W. HORROM & H. E. MORTON. (2010) ChemInform Abstract: Synthesis of N‐(tert‐Butoxycarbonyl)‐3‐(4‐thiazolyl)‐L‐alanine.. ChemInform 22:30.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.