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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 18
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Original Articles

An Improved Procedure for the Large Scale Preparation of 2-Chloro-4,6-dimethoxy-1,3,5-triazine

Jason S. Cronin Lilly Research Laboratories, Chemical Process Research and Development, A Division of Eli Lilly & Company, Indianapolis, IN, 46285–4813
,
Francis O. Ginah Lilly Research Laboratories, Chemical Process Research and Development, A Division of Eli Lilly & Company, Indianapolis, IN, 46285–4813
,
Angela R. Murray Lilly Research Laboratories, Chemical Process Research and Development, A Division of Eli Lilly & Company, Indianapolis, IN, 46285–4813
&
James D. Copp Lilly Research Laboratories, Chemical Process Research and Development, A Division of Eli Lilly & Company, Indianapolis, IN, 46285–4813
Pages 3491-3494 | Received 31 Mar 1996, Published online: 21 Aug 2006

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Matthew C. Uzagare, Yogesh S. Sanghvi & M. M. Salunkhe. (2004) Efficient DMTMM Promoted Nucleoside Loading of CPG Solid Support for Oligonucleotide Synthesis. Synthetic Communications 34:6, pages 1071-1077.
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Articles from other publishers (35)

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Pawel Zassowski, Przemyslaw Ledwon, Aleksandra Kurowska, Artur P. Herman, Mieczyslaw Lapkowski, Vladyslav Cherpak, Zenon Hotra, Pavlo Turyk, Khrystyna Ivaniuk, Pavlo Stakhira, Galyna Sych, Dmytro Volyniuk & Juozas Vidas Grazulevicius. (2018) 1,3,5-Triazine and carbazole derivatives for OLED applications. Dyes and Pigments 149, pages 804-811.
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Pawel Zassowski, Przemyslaw Ledwon, Aleksandra Kurowska, Artur P. Herman, Tomasz Jarosz, Mieczyslaw Lapkowski, Vladyslav Cherpak, Pavlo Stakhira, Laura Peciulyte, Dmytro Volyniuk & Juozas Vidas Grazulevicius. (2017) Efficient synthesis and structural effects of ambipolar carbazole derivatives. Synthetic Metals 223, pages 1-11.
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Arnoosh Khademi Shiraz & Maaroof Zarei. (2014) Application of 2-chloro-4,6-dimethoxy-1,3,5-triazine in the synthesis of 2-azetidinones. Monatshefte für Chemie - Chemical Monthly 146:6, pages 941-946.
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Tina Borke, Françoise M. Winnik, Heikki Tenhu & Sami Hietala. (2015) Optimized triazine-mediated amidation for efficient and controlled functionalization of hyaluronic acid. Carbohydrate Polymers 116, pages 42-50.
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Merritt B. Andrus. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis 1 7 .
Masanori Kitamura, Fumitaka Kawasaki, Kouichi Ogawa, Shuichi Nakanishi, Hiroyuki Tanaka, Kohei Yamada & Munetaka Kunishima. (2014) Role of Linkers in Tertiary Amines That Mediate or Catalyze 1,3,5-Triazine-Based Amide-Forming Reactions. The Journal of Organic Chemistry 79:8, pages 3709-3714.
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Xiao-Jian Li, Jin-Ling Zhang, Yu Geng & Zhong Jin. (2013) Nickel-Catalyzed Suzuki–Miyaura Coupling of Heteroaryl Ethers with Arylboronic Acids. The Journal of Organic Chemistry 78:10, pages 5078-5084.
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Munetaka Kunishima, Takae Ujigawa, Yoshie Nagaoka, Chiho Kawachi, Kazuhito Hioki & Motoo Shiro. (2012) Study on 1,3,5-Triazine Chemistry in Dehydrocondensation: Gauche Effect on the Generation of Active Triazinylammonium Species . Chemistry - A European Journal 18:49, pages 15856-15867.
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Songbai Liu, Wu-Hong Wang, Ya-Li Dang, Yuanqing Fu & Ruocheng Sang. (2012) Rational design and efficient synthesis of a fluorescent-labeled jasmonate. Tetrahedron Letters 53:32, pages 4235-4239.
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Cai Tie & Xin-Xiang Zhang. (2012) A new labelling reagent for glycans analysis by capillary electrophoresis-mass spectrometry. Analytical Methods 4:2, pages 357.
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Cristina Gómez de la Oliva, Pilar Goya Laza & Carmen Ochoa de Ocariz. 2011. Modern Heterocyclic Chemistry. Modern Heterocyclic Chemistry 1777 1864 .
Brad M. Rosen, Mihai Peterca, Kentaro Morimitsu, Andrés E. Dulcey, Pawaret Leowanawat, Ana-Maria Resmerita, Mohammad R. Imam & Virgil Percec. (2011) Programming the Supramolecular Helical Polymerization of Dendritic Dipeptides via the Stereochemical Information of the Dipeptide. Journal of the American Chemical Society 133:13, pages 5135-5151.
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Virgil Percec, Mohammad R. Imam, Mihai Peterca, Wook-Dong Cho & Paul A. Heiney. (2009) Self-Assembling Dendronized Dendrimers. Israel Journal of Chemistry 49:1, pages 55-70.
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G. Giacomelli & A. Porcheddu. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 197 290 .
Grzegorz Blotny. (2006) Recent applications of 2,4,6-trichloro-1,3,5-triazine and its derivatives in organic synthesis. Tetrahedron 62:41, pages 9507-9522.
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Camelia Berghian, Pedro Lameiras, Loïc Toupet, Eric Condamine, Nelly Plé, Alain Turck, Carmen Maiereanu & Mircea Darabantu. (2006) α-(3,7-Dioxa-r-1-azabicyclo[3.3.0]oct-c-5-ylmethoxy)-diazines. Part 1: Synthesis and stereochemistry. Extension to s-triazine series. Tetrahedron 62:31, pages 7319-7338.
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Monica Pintea, Mircea Darabantu, Marijana Fazekas, Pedro Lameiras, Camelia Berghian, Isabelle Delhom, Constantin Bele & Nelly Plé. (2006) FIRST SYNTHESIS, ROTAMERISM AND HERBICIDAL EVALUATION OF SUBSTITUTED s-TRIAZINES WITH SERINOLIC FRAGMENT. Heterocyclic Communications 12:2.
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Simona Samaritani, Giovanni Signore, Corrado Malanga & Rita Menicagli. (2005) Organometallic alkylation of 2-chloro-4,6-dimethoxy-1,3,5-triazine: a study. Tetrahedron 61:18, pages 4475-4483.
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Virgil Percec, Andrés Dulcey, Mihai Peterca, Monica Ilies, Yoshiko Miura, Ulrica Edlund & Paul A. Heiney. (2005) Helical Porous Protein Mimics Self-Assembled from Amphiphilic Dendritic Dipeptides. Australian Journal of Chemistry 58:6, pages 472.
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Munetaka Kunishima, Yasunobu Watanabe, Keiji Terao & Shohei Tani. (2004) Substrate-Specific Amidation of Carboxylic Acids in a Liquid?Liquid Two-Phase System Using Cyclodextrins as Inverse Phase-Transfer Catalysts. European Journal of Organic Chemistry 2004:22, pages 4535-4540.
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Yasunobu Watanabe, Takako Fuji, Kazuhito Hioki, Shohei Tani & Munetaka Kunishima. (2004) Development of a Simple System for Dehydrocondensation Using Solid-Phase Adsorption of a Water-Soluble Dehydrocondensing Reagent (DMT-MM). Chemical and Pharmaceutical Bulletin 52:10, pages 1223-1226.
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Radek Pohl & Pavel Anzenbacher. (2003) Emission Color Tuning in AlQ 3 Complexes with Extended Conjugated Chromophores . Organic Letters 5:16, pages 2769-2772.
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D. Scott Coffey. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Simona Samaritani & Rita Menicagli. (2002) Palladium on carbon catalyzed cross-coupling between alk-1-ynes and 2-chloro-4,6-dialkoxy-1,3,5-triazines. Tetrahedron 58:7, pages 1381-1386.
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Zbigniew J. Kamiński, Beata Kolesińska, Janina E. Kamińska & Józef Góra. (2001) A Novel Generation of Coupling Reagents. Enantiodifferentiating Coupling Reagents Prepared in Situ from 2-Chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) and Chiral Tertiary Amines. The Journal of Organic Chemistry 66:19, pages 6276-6281.
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Lidia De Luca, Giampaolo Giacomelli & Maurizio Taddei. (2001) An Easy and Convenient Synthesis of Weinreb Amides and Hydroxamates. The Journal of Organic Chemistry 66:7, pages 2534-2537.
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Munetaka Kunishima, Chiho Kawachi, Kazuhito Hioki, Keiji Terao & Shohei Tani. (2001) Formation of carboxamides by direct condensation of carboxylic acids and amines in alcohols using a new alcohol- and water-soluble condensing agent: DMT-MM. Tetrahedron 57:8, pages 1551-1558.
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Zbigniew J. Kamiński. (2000) Triazine-based condensing reagents. Biopolymers 55:2, pages 140-164.
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Massimo Falorni, Giampaolo Giacomelli, Andrea Porcheddu & Maurizio Taddei. (1999) A Simple Method for the Reduction of Carboxylic Acids to Aldehydes or Alcohols Using H 2 and Pd/C . The Journal of Organic Chemistry 64:24, pages 8962-8964.
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Munetaka Kunishima, Chiho Kawachi, Jun Monta, Keiji Terao, Fumiaki Iwasaki & Shohei Tani. (1999) 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride: an efficient condensing agent leading to the formation of amides and esters. Tetrahedron 55:46, pages 13159-13170.
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Munetaka Kunishima, Chiho Kawachi, Fumiaki Iwasaki, Keiji Terao & Shohei Tani. (1999) Synthesis and characterization of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. Tetrahedron Letters 40:29, pages 5327-5330.
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Heather L. Rayle & Lisa Fellmeth. (1999) Development of a Process for Triazine-Promoted Amidation of Carboxylic Acids. Organic Process Research & Development 3:3, pages 172-176.
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J. S. CRONIN, F. O. GINAH, A. R. MURRAY & J. D. COPP. (2010) ChemInform Abstract: An Improved Procedure for the Large Scale Preparation of 2‐Chloro‐4,6‐ dimethoxy‐1,3,5‐triazine.. ChemInform 27:50.
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