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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 28, 1998 - Issue 24
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Original Articles

Transformation of 1,3,4-Oxadiazoles to 1,3,4-Thiadiazoles Using Thiourea

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Pages 4611-4617 | Received 22 Jun 1998, Published online: 22 Aug 2006

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Amr Hassan Moustafa, Doaa H. Ahmed, Mohamed T. M. El-Wassimy & Mamdouh F. A. Mohamed. (2021) Synthesis, antimicrobial studies, and molecular docking of some new dihydro-1,3,4-thiadiazole and pyrazole derivatives derived from dithiocarbazates. Synthetic Communications 51:4, pages 570-584.
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D. Doddramappa Shridevi, Srikantamurthy Ningaiah, Narayan U. Kuduva, Raad K. Yhya & Kuriya M. Lokanatha Rai. (2015) Solvent-Free Green Synthesis of Azines and Their Conversion to 2,5-Disubstituted-1,3,4-thiadiazoles. Synthetic Communications 45:24, pages 2869-2875.
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Ebraheem Abdu Musad & K. M. Lokanatha Rai. (2010) Synthesis of Substituted Isoxazoles and Pyrazoles from α-α-Dioxoketen Dithioacetals Under Solvothermal Conditions. Synthetic Communications 40:23, pages 3569-3576.
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B. Gierczyk & M. Zalas. (2005) SYNTHESIS OF SUBSTITUTED 1,3,4-THIADIAZOLES USING LAWESSON'S REAGENT. Organic Preparations and Procedures International 37:3, pages 213-222.
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M.K. Gond, Shivendra Kumar Pandey, S. Chandra, N. Tiwari, M.K. Bharty, B. Maiti, D. Katiyar & R.J. Butcher. (2022) Zinc(II) catalyzed synthesis of 2-(4-methoxyphenyl)-5-(2-pyridyl)-1,3,4-thiadiazole: Characterizations, crystal structure, DFT calculation, Hirshfeld surface analysis, and molecular docking analysis. Journal of Molecular Structure 1267, pages 133586.
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Jürgen Schatz, Kemal Gogić & Tobias Benkert. 2022. Comprehensive Heterocyclic Chemistry IV. Comprehensive Heterocyclic Chemistry IV 407 447 .
Zabiulla, Fares Hezam Al-Ostoot, Asha M. S, Mohammed Al-Ghorbani & Shaukath Ara Khanum. (2021) Recent investigation on heterocycles with one nitrogen [piperidine, pyridine and quinoline], two nitrogen [1,3,4-thiadiazole and pyrazole] and three nitrogen [1,2,4-triazole]: a review. Journal of the Iranian Chemical Society 19:1, pages 23-54.
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Navjeet KaurNavjeet Kaur. 2022. Lawesson’s Reagent in Heterocycle Synthesis. Lawesson’s Reagent in Heterocycle Synthesis 115 147 .
Pengfei Niu, Jingya Yang, Yong Yuan, Yongxin Zhang, Chenxing Zhou, Xiazhen Bao & Congde Huo. (2021) Photocatalyzed redox-neutral decarboxylative alkylation of heteroaryl methanamines. Green Chemistry 23:2, pages 774-779.
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Anil Kumar Gunthanakkala, Madhu Sekhar Mangali, Padmavathi Venkatapuram & Padmaja Adivireddy. (2020) Synthesis, characterization and antioxidant activity of bis (arylsulfonylmethyl/arylaminosulfonylmethylazolyl) pyridines . Journal of Heterocyclic Chemistry 57:12, pages 4164-4174.
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Lidia Lungu, Alexandru Ciocarlan, Crina Smigon, Ilker Ozer, Sergiu Shova, Iacob Gutu, Nicoleta Vornicu, Ionel Mangalagiu, Michele D’Ambrosio & Aculina Aricu. (2020) Synthesis and Evaluation of Biological Activity of Homodrimane Sesquiterpenoids Bearing 1,3,4-Oxadiazole or 1,3,4-Thiadiazole Units. Chemistry of Heterocyclic Compounds 56:5, pages 578-585.
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Sumana Y. Kotian, Chakrabhavi Dhananjaya Mohan, Aloir A. Merlo, Shobith Rangappa, S. Chandra Nayak, K.M. Lokanatha Rai & Kanchugarakoppal S. Rangappa. (2020) Small molecule based five-membered heterocycles: A view of liquid crystalline properties beyond the biological applications. Journal of Molecular Liquids 297, pages 111686.
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Mangali Madhu Sekhar, Gudi Yamini, Kuppi Reddy Gari Divya, Venkatapuram Padmavathi & Adivireddy Padmaja. (2019) Synthesis and bioassay of a new class of disubstituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles. Medicinal Chemistry Research 28:7, pages 1049-1062.
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Vishnu Ji Ram, Arun Sethi, Mahendra Nath & Ramendra Pratap. 2019. The Chemistry of Heterocycles. The Chemistry of Heterocycles 149 478 .
Anil Kumar Gunthanakkala, Madhusekhar Mangali, Yamini Gudi, Sreenivasulu Tatha, Padmavathi Venkatapuram & Padmaja Adivireddy. (2018) Synthesis and Antioxidant Activity of Bis (Aroyl/Arylsulfonyl Ethenesulfonylmethylazolyl)Pyridines. Journal of Heterocyclic Chemistry 55:9, pages 2142-2150.
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Karolina Jasiak, Agnieszka Kudelko, Monika Wróblowska, Anna Biernasiuk, Anna Malm & Maria Krawczyk. (2017) Convenient Synthesis and Biological Activity of Mono and Diacyl 2,5-Dimercapto-1,3,4-thiadiazole Derivatives. Journal of Heterocyclic Chemistry 54:6, pages 3241-3249.
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Padmaja Adivireddy, Pedamalakondaiah Devanaboina, Lavanya Gopala & Rajasekhar Chittoor. (2016) Synthesis of Symmetrical Bis(5-substituted oxadiazolyl/thiadiazolyl/triazolylmethyl)sulfones. Journal of Heterocyclic Chemistry 53:5, pages 1651-1654.
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Zi-Ning Cui, Ya-Sheng Li, De-Kun Hu, Hao Tian, Jia-Zhen Jiang, Yuan Wang & Xiao-Jing Yan. (2016) Synthesis and fungicidal activity of novel 2,5-disubstituted-1,3,4- thiadiazole derivatives containing 5-phenyl-2-furan. Scientific Reports 6:1.
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Adivireddy Padmaja, Devanaboina Pedamalakondaiah, Gundala Sravya, Guda Mallikarjuna Reddy & Malaka Venkateshwarulu Jyothi Kumar. (2014) Synthesis and antioxidant activity of a new class of sulfone/sulfonamide-linked bis(oxadiazoles), bis(thiadiazoles), and bis(triazoles). Medicinal Chemistry Research 24:5, pages 2011-2020.
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Mallikarjuna Reddy Guda, Sravya Gundala, Venkatapuram Padmavathi & Adivireddy Padmaja. (2014) An efficient synthesis of styryl 1,3,4-thiadiazoles using Lawesson’s reagent and Propylphosphonic anhydride-precursors for bis heterocycles. Arabian Journal of Chemistry 7:6, pages 947-954.
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Yang Hu, Cui-Yun Li, Xiao-Ming Wang, Yong-Hua Yang & Hai-Liang Zhu. (2014) 1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry. Chemical Reviews 114:10, pages 5572-5610.
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Md.A. Rahman, Mohammad R. Karim, Md. Arifuzzaman, Tasneem A. Siddiquee & Aminul H. Mirza. (2014) ZnCl2 catalyzed efficient synthesis of 1,3,4-oxadiazole and 1,3,4-thiadiazole. Tetrahedron Letters 55:21, pages 3267-3273.
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Akkarapalli Muralikrishna, Guda Mallikarjuna Reddy, Gopala Lavanya, Venkatapuram Padmavathi & Adivireddy Padmaja. (2014) Synthesis of a New Class of Sulfonamido Bis Heterocycles-Pyrrolyl/Pyrazolyl-1,3,4-oxadiazoles, 1,3,4-Thiadiazoles, and 1,2,4-Triazoles. Journal of Heterocyclic Chemistry 51:1, pages 179-190.
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Ugo Chiacchio & Giovanni Romeo. 2011. Modern Heterocyclic Chemistry. Modern Heterocyclic Chemistry 1253 1400 .
G. Nagendra, Ravi S. Lamani, N. Narendra & Vommina V. Sureshbabu. (2010) A convenient synthesis of 1,3,4-thiadiazole and 1,3,4-oxadiazole based peptidomimetics employing diacylhydrazines derived from amino acids. Tetrahedron Letters 51:48, pages 6338-6341.
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Fezzeh Aryanasab, Azim Ziyaei Halimehjani & Mohammad R. Saidi. (2010) Dithiocarbamate as an efficient intermediate for the synthesis of 2-amino-1,3,4-thiadiazoles in water. Tetrahedron Letters 51:5, pages 790-792.
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. 2010. Handbook of Heterocyclic Chemistry. Handbook of Heterocyclic Chemistry 917 970 .
K. Jailakshmi, K. M. Lokanatha Rai & K. Byrappa. (2008) Synthesis of benzhydrol derivatives by metal imidozalen catalysed electrophilic addition of aromatic aldehyde to hydrocarbons under solvothermal condition. Journal of Materials Science 43:7, pages 2254-2257.
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P.A. Koutentis & C.P. Constantinides. 2008. Comprehensive Heterocyclic Chemistry III. Comprehensive Heterocyclic Chemistry III 567 605 .
László Somogyi. (2009) Synthesis, oxidation and dehydrogenation of cyclic N,O ‐ and N,S ‐acetals. Part III. Transformation of N,O ‐acetals: 3‐acyl‐1,3,4‐oxadiazolines . Journal of Heterocyclic Chemistry 44:6, pages 1235-1246.
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E. Aparna, K. M. Lokanatha Rai, M. Sureshbabu, R. L. Jagadish, S. L. Gaonkar & K. Byrappa. (2006) RETRACTED ARTICLE: Synthesis of thioesters and thioamides under solvothermal condition using thiourea as thionating agent. Journal of Materials Science 41:5, pages 1391-1393.
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K.M Lokanatha Rai & N Linganna. (2000) Synthesis and evaluation of antimitotic activity of alkylated 2-amino-1,3,4-oxadiazole derivatives. Il Farmaco 55:5, pages 389-392.
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Paul A. Bradley & David J. Wilkins. 2000. A critical review of the 1999 literature preceded by three chapters on current heterocyclic topics. A critical review of the 1999 literature preceded by three chapters on current heterocyclic topics 185 203 .
N. Linganna & K. M. Lokanatha Rai. (2010) ChemInform Abstract: Transformation of 1,3,4‐Oxadiazoles to 1,3,4‐Thiadiazoles Using Thiourea.. ChemInform 30:12.
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