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Scientific Article

The effect of different combinations of lignocaine, ketoprofen, xylazine and tolazoline on the acute cortisol response to dehorning in calves

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Pages 219-226 | Accepted 14 Mar 2003, Published online: 22 Feb 2011

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Read on this site (6)

EL Cuttance, WA Mason, DA Yang, RA Laven, J McDermott & K Inglis. (2019) Effects of a topically applied anaesthetic on the behaviour, pain sensitivity and weight gain of dairy calves following thermocautery disbudding with a local anaesthetic. New Zealand Veterinary Journal 67:6, pages 295-305.
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Amritlal Saini & Shashi Saijpaul. (2015) Performance assessment of Beetal kids due to disbudding pre-medication under stall-fed conditions. Journal of Applied Animal Research 43:1, pages 69-76.
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TJ Gibson, CB Johnson, KJ Stafford, SL Mitchinson & DJ Mellor. (2007) Validation of the acute electroencephalographic responses of calves to noxious stimulus with scoop dehorning. New Zealand Veterinary Journal 55:4, pages 152-157.
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KJ Stafford, JP Chambers, SP Sylvester, PR Kenyon, ST Morris, I Lizarraga & G de Nicolo. (2006) Stress caused by laparoscopy in sheep and its alleviation. New Zealand Veterinary Journal 54:3, pages 109-113.
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KJ Stafford & DJ Mellor. (2005) The welfare significance of the castration of cattle: A review. New Zealand Veterinary Journal 53:5, pages 271-278.
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Articles from other publishers (46)

Lorenzo Alvarez, Angélica Terrazas, Susana Rojas & Francisco Galindo. (2023) Cortisol and pain-related behavior in hot-iron disbudded goat kids sedated with xylazine and locally infiltrated with lidocaine. Journal of Veterinary Behavior 63, pages 42-47.
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Cassandra N. Reedman, Todd F. Duffield, Trevor J. DeVries, Kerry D. Lissemore & Charlotte B. Winder. (2022) Graduate Student Literature Review: Role of pain mitigation on the welfare of dairy calves undergoing disbudding. Journal of Dairy Science 105:8, pages 6809-6819.
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Safaa Amin, Romy Wagner, Helena Fieseler, Awad Rizk, Marion Schmicke, Joachim Spilke, Norbert Mielenz, Walter Baumgartner, Melanie Schären-Bannert & Alexander Starke. (2022) Sedation With Xylazine Hydrochloride Decreases the Stress Response in Merino Meat Sheep During Routine Hoof Trimming in a Tilt Table. Frontiers in Animal Science 2.
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Megan Verdon. (2021) A review of factors affecting the welfare of dairy calves in pasture-based production systems. Animal Production Science 62:1, pages 1-20.
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Hannah N Phillips & Bradley J Heins. (2021) Evaluation of an herbal therapy to alleviate acute pain and stress of disbudded dairy calves under organic management1. Translational Animal Science 5:2.
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Johannes Kretschmann, Lisa Scherf, Marie Luise Fischer, Matthias Kaiser, Hendrik Müller, Joachim Spilke, Norbert Mielenz, Gerd Möbius, Lilli Bittner, Ilka Steinhöfel, Walter Baumgartner & Alexander Starke. (2020) Einfluss der thermischen Enthornung mit unterschiedlichem Schmerzmanagement auf die Gesundheit von Kälbern. Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere 48:05, pages 318-326.
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Crystal Espinoza, Sabrina Lomax & Peter Windsor. (2020) The Effect of Topical Anaesthesia on the Cortisol Responses of Calves Undergoing Dehorning. Animals 10:2, pages 312.
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Elbialy Elmorsy, Khalid Abouelnasr, Esam Mosbah & Adel Zaghloul. (2019) Evaluation of Multimodal Anesthetic Drugs Combination in Goats undergoing laparo-ovariectomy. Mansoura Veterinary Medical Journal 20:4, pages 1-8.
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Thomas Ede, Marina A. G. von Keyserlingk & Daniel M. Weary. (2019) Assessing the affective component of pain, and the efficacy of pain control, using conditioned place aversion in calves. Biology Letters 15:10, pages 20190642.
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T. Ede, M.A.G. von Keyserlingk & D.M. Weary. (2019) Efficacy of xylazine in neonatal calves via different routes of administration. The Veterinary Journal 247, pages 57-60.
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Mette S. Herskin & Bodil H. Nielsen. (2018) Welfare Effects of the Use of a Combination of Local Anesthesia and NSAID for Disbudding Analgesia in Dairy Calves—Reviewed Across Different Welfare Concerns. Frontiers in Veterinary Science 5.
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Alessandro Mirra, Claudia Spadavecchia, Rupert Bruckmaier, Andreas Gutzwiller & Daniela Casoni. (2018) Acute pain and peripheral sensitization following cautery disbudding in 1- and 4-week-old calves. Physiology & Behavior 184, pages 248-260.
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Sarah J.J. Adcock & Cassandra B. Tucker. 2018. Advances in Cattle Welfare. Advances in Cattle Welfare 157 198 .
SYN Hambleton & TJ Gibson. (2023) Study investigating the attitudes and opinions of cattle farmers and veterinarians in the UK on the use of non-steroidal anti-inflammatory drugs (NSAIDs) for post-disbudding analgesia of calves. Animal Welfare 26:3, pages 323-334.
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Oswald Ndi Nfor, Jacky Peng-Wen Chan, Michel Kere & Huo-Cheng Peh. (2016) Disbudding pain: The benefits of disbudding goat kids with dexmedetomidine hydrochloride. Small Ruminant Research 139, pages 60-66.
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Richard Cooper. (2016) Improving the welfare of calves at castration and disbudding / dehorning in the UK. Livestock 21:2, pages 84-90.
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D. Caray, A. de Boyer des Roches, S. Frouja, S. Andanson & I. Veissier. (2015) Hot-iron disbudding: stress responses and behavior of 1- and 4-week-old calves receiving anti-inflammatory analgesia without or with sedation using xylazine. Livestock Science 179, pages 22-28.
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Jack J. Windig, G. Cozzi & I. Vessier. (2015) Introduction to the special issue on alternatives for cattle dehorning. Livestock Science 179, pages 1-3.
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Matthew L. Stock & Johann F. Coetzee. (2015) Clinical Pharmacology of Analgesic Drugs in Cattle. Veterinary Clinics of North America: Food Animal Practice 31:1, pages 113-138.
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E. M. Mintline, A. Varga, J. Banuelos, K. A. Walker, B. Hoar, Daniel Drake, D.M. Weary, J. F. Coetzee, M. L. Stock & C. B. Tucker. (2014) Healing of surgical castration wounds: a description and an evaluation of flunixin1. Journal of Animal Science 92:12, pages 5659-5665.
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Alexander Valverde. 2013. Pain Management in Veterinary Practice. Pain Management in Veterinary Practice 359 371 .
D. Pieler, W. Peinhopf, A.C. Becher, J.E. Aurich, S. Rose-Meierhöfer, R. Erber, E. Möstl & C. Aurich. (2013) Physiological and behavioral stress parameters in calves in response to partial scrotal resection, orchidectomy, and Burdizzo castration. Journal of Dairy Science 96:10, pages 6378-6389.
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Matthew L. Stock, Sarah L. Baldridge, Dee Griffin & Johann F. Coetzee. (2013) Bovine Dehorning. Veterinary Clinics of North America: Food Animal Practice 29:1, pages 103-133.
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Erin M. Mintline, Mairi Stewart, Andrea R. Rogers, Neil R. Cox, Gwyneth A. Verkerk, Joseph M. Stookey, James R. Webster & Cassandra B. Tucker. (2013) Play behavior as an indicator of animal welfare: Disbudding in dairy calves. Applied Animal Behaviour Science 144:1-2, pages 22-30.
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J. Huber, T. Arnholdt, E. Möstl, C.-C. Gelfert & M. Drillich. (2013) Pain management with flunixin meglumine at dehorning of calves. Journal of Dairy Science 96:1, pages 132-140.
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Awad Rizk, Sarah Herdtweck, Jennifer Offinger, Henning Meyer, Adel Zaghloul & Juergen Rehage. (2012) The use of xylazine hydrochloride in an analgesic protocol for claw treatment of lame dairy cows in lateral recumbency on a surgical tipping table. The Veterinary Journal 192:2, pages 193-198.
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R. Guatteo, O. Levionnois, D. Fournier, D. Guémené, K. Latouche, C. Leterrier, P. Mormède, A. Prunier, J. Servière, C. Terlouw & P. Le Neindre. (2012) Minimising pain in farm animals: the 3S approach – ‘Suppress, Substitute, Soothe’. Animal 6:8, pages 1261-1274.
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Kevin J. Stafford & David J. Mellor. (2011) Addressing the pain associated with disbudding and dehorning in cattle. Applied Animal Behaviour Science 135:3, pages 226-231.
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Sarah L. Baldridge, Johann F. Coetzee, Steve S. Dritz, James B. Reinbold, Ronette Gehring, James Havel & Butch Kukanich. (2011) Pharmacokinetics and physiologic effects of intramuscularly administered xylazine hydrochloride-ketamine hydrochloride-butorphanol tartrate alone or in combination with orally administered sodium salicylate on biomarkers of pain in Holstein calves following castration and dehorning. American Journal of Veterinary Research 72:10, pages 1305-1317.
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Donald M. Broom. (2010) Cognitive ability and awareness in domestic animals and decisions about obligations to animals. Applied Animal Behaviour Science 126:1-2, pages 1-11.
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A. Heinrich, T.F. Duffield, K.D. Lissemore & S.T. Millman. (2010) The effect of meloxicam on behavior and pain sensitivity of dairy calves following cautery dehorning with a local anesthetic. Journal of Dairy Science 93:6, pages 2450-2457.
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G. Stilwell, R.C. Carvalho, N. Carolino, M.S. Lima & D.M. Broom. (2010) Effect of hot-iron disbudding on behaviour and plasma cortisol of calves sedated with xylazine. Research in Veterinary Science 88:1, pages 188-193.
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Lorenzo Alvarez, Ricardo A. Nava, América Ramírez, Edith Ramírez & Javier Gutiérrez. (2009) Physiological and behavioural alterations in disbudded goat kids with and without local anaesthesia. Applied Animal Behaviour Science 117:3-4, pages 190-196.
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A. Heinrich, T.F. Duffield, K.D. Lissemore, E.J. Squires & S.T. Millman. (2009) The impact of meloxicam on postsurgical stress associated with cautery dehorning. Journal of Dairy Science 92:2, pages 540-547.
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George Stilwell, Rita Campos de Carvalho, Miguel S. Lima & Donald M. Broom. (2009) Effect of caustic paste disbudding, using local anaesthesia with and without analgesia, on behaviour and cortisol of calves. Applied Animal Behaviour Science 116:1, pages 35-44.
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G. Stilwell, M.S. Lima & D.M. Broom. (2008) Comparing plasma cortisol and behaviour of calves dehorned with caustic paste after non-steroidal-anti-inflammatory analgesia. Livestock Science 119:1-3, pages 63-69.
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G Stilwell G, C de Carvalho R, MS Lima & DM Broom. (2023) The effect of duration of manual restraint during blood sampling on plasma cortisol levels in calves. Animal Welfare 17:4, pages 383-385.
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D. R. Paull, I. G. Colditz, C. Lee, S. J. Atkinson & A. D. Fisher. (2008) Effectiveness of non-steroidal anti-inflammatory drugs and epidural anaesthesia in reducing the pain and stress responses to a surgical husbandry procedure (mulesing) in sheep. Australian Journal of Experimental Agriculture 48:7, pages 1034.
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T.J. Doherty, H.G. Kattesh, R.J. Adcock, M.G. Welborn, A.M. Saxton, J.L. Morrow & J.W. Dailey. (2007) Effects of a Concentrated Lidocaine Solution on the Acute Phase Stress Response to Dehorning in Dairy Calves. Journal of Dairy Science 90:9, pages 4232-4239.
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Kevin J. Stafford & David J. Mellor. (2007) Pain: A developing issue in veterinary medicine. The Veterinary Journal 174:2, pages 225-226.
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Kevin Stafford. (2007) Castrating older lambs: What are the issues?. The Veterinary Journal 173:3, pages 477.
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Susanne Melches, Sibylle C. Mellema, Marcus G. Doherr, Beat Wechsler & Adrian Steiner. (2007) Castration of lambs: A welfare comparison of different castration techniques in lambs over 10 weeks of age. The Veterinary Journal 173:3, pages 554-563.
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K.J. Stafford & D.J. Mellor. (2005) Dehorning and disbudding distress and its alleviation in calves. The Veterinary Journal 169:3, pages 337-349.
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K.J. Vickers, L. Niel, L.M. Kiehlbauch & D.M. Weary. (2005) Calf Response to Caustic Paste and Hot-Iron Dehorning Using Sedation With and Without Local Anesthetic. Journal of Dairy Science 88:4, pages 1454-1459.
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Pascale Aubry. (2005) Routine surgical procedures in dairy cattle under field conditions: Abomasal surgery, dehorning, and tail docking. Veterinary Clinics of North America: Food Animal Practice 21:1, pages 55-72.
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