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Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 11
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Research Article

Characterization of testosterone metabolism and 7-hydroxycoumarin conjugation by rat and human liver slices after storage in liquid nitrogen for 1 h up to 6 months

C. Granhall Research DMPK, AstraZeneca R&D Södertälje, S-151 85 Södertälje, Sweden
,
E. Floby Department of Medical Laboratory Sciences, Division of Clinical Pharmacology and Technology, Karolinska Institute, Huddinge University Hospital, S-141 86 Huddinge, Sweden
,
A. Nordmark Division of Surgery, Centre for Surgical Sciences, Huddinge University Hospital, S-141 85 Huddinge, Sweden
,
A. Orzechowski Research DMPK, AstraZeneca R&D Södertälje, S-151 85 Södertälje, Sweden
,
A. Thörne Department of Medical Laboratory Sciences, Division of Clinical Pharmacology and Technology, Karolinska Institute, Huddinge University Hospital, S-141 86 Huddinge, Sweden
,
G. Tybring Division of Surgery, Centre for Surgical Sciences, Huddinge University Hospital, S-141 85 Huddinge, Sweden
&
A.-K. Sohlenius-Sternbeck Research DMPK, AstraZeneca R&D Södertälje, S-151 85 Södertälje, Sweden
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Pages 985-996 | Published online: 22 Sep 2008

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Gregory M. Fahy, Na Guan, Inge A. M. de Graaf, Yuansheng Tan, Lenetta Griffin & Geny M. M. Groothuis. (2013) Cryopreservation of precision-cut tissue slices. Xenobiotica 43:1, pages 113-132.
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Marc Vermeir, Pieter Annaert, Rao NVS Mamidi, Dirk Roymans, Willem Meuldermans & Geert Mannens. (2005) Cell-based models to study hepatic drug metabolism and enzyme induction in humans. Expert Opinion on Drug Metabolism & Toxicology 1:1, pages 75-90.
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Articles from other publishers (4)

Ying Zhu, Qiong Shi, Qi Peng, Yue Gao, Ting Yang, Yu Cheng, Hao Wang, Yetao Luo, Ailong Huang, Tong‑Chuan He & Jiaming Fan. (2019) A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies. International Journal of Molecular Medicine.
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Alexander V. LyubimovCostas Ioannides & Brian G. Lake. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 26 .
R. Glöckner, A. Lieder & A. Lupp. (2008) Determination of CYP activity in precision-cut liver slices: whether to use intact slices or slice homogenate. Analytical and Bioanalytical Chemistry 392:6, pages 1167-1172.
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H. Axelsson, C. Granhall, E. Floby, Y. Jaksch, M. Svedling & A.-K. Sohlenius-Sternbeck. (2003) Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes. Toxicology in Vitro 17:4, pages 481-488.
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