Xenobiotica, Volume 32, Issue 11 (2002)

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Xenobiotica, Volume 32, Issue 11 (2002)

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Research Article

Article
Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells
J. Andrews, M. F. Abd-Ellah, N. L. Randolph, K. E. Kenworthy, D. J. Carlile, T. Friedberg & J. B. Houston
Pages: 937-947
Published online: 22 Sep 2008
AbstractforComparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells | References | PDF (228.6 KB)
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Article
In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone
Z. Yan, G. W. Caldwell, W. N. Wu, L. A. McKown, B. Rafferty, W. Jones & J. A. Masucci
Pages: 949-962
Published online: 22 Sep 2008
AbstractforIn vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone | References | PDF (274.2 KB)
  • 135 Views
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Article
Decreased activity of hepatic P-glycoprotein in the isolated perfused liver of the adjuvant arthritis rat
M. Achira, R. Totsuka & T. Kume
Pages: 963-973
Published online: 22 Sep 2008
AbstractforDecreased activity of hepatic P-glycoprotein in the isolated perfused liver of the adjuvant arthritis rat | References | PDF (243.9 KB)
  • 34 Views
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Article
Differential induction of midazolam metabolism in the small intestine and liver by oral and intravenous dexamethasone pretreatment in rat
S. L. Eeckhoudt, Y. Horsmans & R. K. Verbeeck
Pages: 975-984
Published online: 22 Sep 2008
AbstractforDifferential induction of midazolam metabolism in the small intestine and liver by oral and intravenous dexamethasone pretreatment in rat | References | PDF (236.4 KB)
  • 172 Views
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Article
Characterization of testosterone metabolism and 7-hydroxycoumarin conjugation by rat and human liver slices after storage in liquid nitrogen for 1 h up to 6 months
C. Granhall, E. Floby, A. Nordmark, A. Orzechowski, A. Thörne, G. Tybring & A.-K. Sohlenius-Sternbeck
Pages: 985-996
Published online: 22 Sep 2008
AbstractforCharacterization of testosterone metabolism and 7-hydroxycoumarin conjugation by rat and human liver slices after storage in liquid nitrogen for 1 h up to 6 months | References | PDF (267.1 KB)
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Article
Comparison of rat and human cytochrome P450 (CYP) sources of N-alkylprotoporphyrin IX. Formation after interaction with porphyrinogenic xenobiotics: studies with cDNA-expressed single CYP enzymes
J. T. Gamble, K. Nakatsu & G. S. Marks
Pages: 997-1006
Published online: 22 Sep 2008
AbstractforComparison of rat and human cytochrome P450 (CYP) sources of N-alkylprotoporphyrin IX. Formation after interaction with porphyrinogenic xenobiotics: studies with cDNA-expressed single CYP enzymes | References | PDF (245.9 KB)
  • 188 Views
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Article
Changes in glutathione-redox balance induced by hexachlorocyclohexane and lindane in CHO-K1 cells
A. J. García-Fernández, A. E. Bayoumi, Y. Pérez-Pertejo, D. Romero, C. Ordóñez, R. M. Reguera, R. Balaña-Fouce & D. Ordóñez
Pages: 1007-1016
Published online: 22 Sep 2008
AbstractforChanges in glutathione-redox balance induced by hexachlorocyclohexane and lindane in CHO-K1 cells | References | PDF (230.3 KB)
  • 17 Views
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Article
In vitro biotransformation of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine by mouse liver microsomes
M. Rypka, J. Veselý, Z. Chmela, D. Riegrová, K. Červenková, L. Havlíček, K. Lemr, J. Hanuš, B. Černý, J. Lukeš & K. Michalíková
Pages: 1017-1031
Published online: 22 Sep 2008
AbstractforIn vitro biotransformation of 2,6,9-trisubstituted purine-derived cyclin-dependent kinase inhibitor bohemine by mouse liver microsomes | References | PDF (308.6 KB)
  • 54 Views
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Article
Induction of cytochrome P4501A1 by autoclavable culture medium change in HepG2 cells
Q. Feng, T. Kumagai, Y. Nakamura, K. Uchida & T. Osawa
Pages: 1033-1043
Published online: 22 Sep 2008
AbstractforInduction of cytochrome P4501A1 by autoclavable culture medium change in HepG2 cells | References | PDF (401 KB)
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Article
Disposition of LY333531, a selective protein kinase C β inhibitor, in the Fischer 344 rat and beagle dog
J. L. Burkey, K. M. Campanale, D. D. O'Bannon, J. W. Cramer & N. A. Farid
Pages: 1045-1052
Published online: 22 Sep 2008
AbstractforDisposition of LY333531, a selective protein kinase C β inhibitor, in the Fischer 344 rat and beagle dog | References | PDF (242.7 KB)
  • 66 Views
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Article
Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
Xiao-Ping Chen, Xing-Mei Han, Chang-Hong Jiang, Song-Lin Huang, Zhao-Qian Liu, Bing Zhu, Gan Zhou & Hong-Hao Zhou
Pages: 1053-1062
Published online: 22 Sep 2008
AbstractforPhenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population | References | PDF (276.2 KB)
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