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Kazunori Iwanaga, Tatsuya Honjo, Makoto Miyazaki & Masawo Kakemi. (2013) Time-dependent changes in hepatic and intestinal induction of cytochrome P450 3A after administration of dexamethasone to rats. Xenobiotica 43:9, pages 765-773.
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Hiroshi Komura & Masahiro Iwaki. (2011) In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences. Drug Metabolism Reviews 43:4, pages 476-498.
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Naoki Kamada, Keigo Yamada, Masaaki Odomi, Tadashi Mukai, Toru Nishibayashi, Ken-ichi Ogawara, Toshikiro Kimura & Kazutaka Higaki. (2011) Sex differences in pharmacokinetics of cilostazol in rats. Xenobiotica 41:10, pages 903-913.
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S. Kurosawa, S. Uchida, Y. Ito,S. Yamada. (2009) Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats. Xenobiotica 39:2, pages 162-170.
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J. R. Kenny & K. Grime. (2006) Pharmacokinetic consequences of time-dependent inhibition using the isolated perfused rat liver model. Xenobiotica 36:5, pages 351-365.
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Takushi Kanazu, Noboru Okamura, Yoshitaka Yamaguchi, Takahiko Baba & Masahiro Koike. (2005) Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug–drug interaction model rats. Xenobiotica 35:4, pages 305-317.
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Articles from other publishers (18)
Marta Rysz, Anima M. Schäfer, Nikolaos Paloumpis, Jonny Kinzi, Karin Brecht, Isabell Seibert, Seraina Schmidlin, Katja In-Albon, Daniel Ricklin & Henriette E. Meyer zu Schwabedissen. (2024)
Humanization of
SLCO2B1
in Rats Increases rCYP3A1 Protein Expression but Not the Metabolism of Erlotinib to OSI-420
. Journal of Pharmacology and Experimental Therapeutics 389:1, pages 87-95.
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Mahmoud Al‐Kofahi, William S. Oetting, David P. Schladt, Rory P. Remmel, Weihua Guan, Baolin Wu, Casey R. Dorr, Roslyn B. Mannon, Arthur J. Matas, Ajay K. Israni & Pamala A. Jacobson. (2021) Precision Dosing for Tacrolimus Using Genotypes and Clinical Factors in Kidney Transplant Recipients of European Ancestry. The Journal of Clinical Pharmacology 61:8, pages 1035-1044.
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K. Sandy Pang, H. Benson Peng & Keumhan Noh. (2020) The Segregated Intestinal Flow Model (SFM) for Drug Absorption and Drug Metabolism: Implications on Intestinal and Liver Metabolism and Drug–Drug Interactions. Pharmaceutics 12:4, pages 312.
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Jing Wen, Yuan Shen, Min Zhang, Chao Wang, Yalan Xiang, Hualin Cai, Pingfei Fang & Huande Li. (2019) Dexamethasone changes the pharmacokinetics of amitriptyline and reduces its accumulation in rat brain: The roles of P-gp and cyp3a2. Journal of Pharmacological Sciences 140:1, pages 54-61.
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K Sanghavi, R C Brundage, M B Miller, D P Schladt, A K Israni, W Guan, W S Oetting, R B Mannon, R P Remmel, A J Matas & P A Jacobson. (2015) Genotype-guided tacrolimus dosing in African-American kidney transplant recipients. The Pharmacogenomics Journal 17:1, pages 61-68.
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Sheila Annie Peters, Christopher R. Jones, Anna-Lena Ungell & Oliver J. D. Hatley. (2016) Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models. Clinical Pharmacokinetics 55:6, pages 673-696.
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K. Sandy Pang & Edwin C. Y. Chow. (2012)
Commentary: Theoretical Predictions of Flow Effects on Intestinal and Systemic Availability in Physiologically Based Pharmacokinetic Intestine Models: The Traditional Model, Segregated Flow Model, and Q
Gut
Model
. Drug Metabolism and Disposition 40:10, pages 1869-1877.
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Liang Li, Zai-quan Li, Chen-hui Deng, Miao-ran Ning, Han-qing Li, Shan-shan Bi, Tian-yan Zhou & Wei Lu. (2012) A mechanism-based pharmacokinetic/pharmacodynamic model for CYP3A1/2 induction by dexamethasone in rats. Acta Pharmacologica Sinica 33:1, pages 127-136.
Crossref
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Jun‐ichi Kusaba, Noriko Kajikawa, Hiromu Kawasaki, Yuji Kurosaki & Tetsuya Aiba. (2012) Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol‐induced acute renal failure. Biopharmaceutics & Drug Disposition 33:1, pages 22-29.
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Philippe Bonnefille, Zerrin Sezgin-Bayindir, Haouaria Belkhelfa, Cécile Arellano, Peggy Gandia, John Woodley & Georges Houin. (2011) The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine. Fundamental & Clinical Pharmacology 25:1, pages 104-114.
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Ryuji Kato, Satoshi Yamashita, Jun Moriguchi, Machiko Nakagawa, Yuri Tsukura, Kagehiro Uchida, Fumio Amano, Yoshihiko Hirotani, Yoshio Ijiri & Kazuhiko Tanaka. (2008) Changes of midazolam pharmacokinetics in Wistar rats treated with lipopolysaccharide: relationship between total CYP and CYP3A2. Innate Immunity 14:5, pages 291-297.
Crossref
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Hiroshi Komura & Masahiro Iwaki. (2008) Species Differences in In Vitro and In Vivo Small Intestinal Metabolism of CYP3A Substrates. Journal of Pharmaceutical Sciences 97:5, pages 1775-1800.
Crossref
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Mónica Garca‐Lóapez, Susana Yenes, Helmut Buschmann & Antoni Torrens. 2007. Antidepressants, Antipsychotics, Anxiolytics. Antidepressants, Antipsychotics, Anxiolytics
951
1087
.
Kewei Zhang, Masanori Kuroha, Yuko Shibata, Eiichi Kokue & Minoru Shimoda. (2006) Effect of oral administration of clinically relevant doses of dexamethasone on regulation of cytochrome P450 subfamilies in hepatic microsomes from dogs and rats. American Journal of Veterinary Research 67:2, pages 329-334.
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Kewei ZHANG, Sayaka KOHNO, Masanori KUROHA, Eiichi KOKUE & Minoru SHIMODA. (2006) Clinical Oral Doses of Dexamethasone Decreases Intrinsic Clearance of Quinidine, A Cytochrome P450 3A Substrate in Dogs. Journal of Veterinary Medical Science 68:9, pages 903-907.
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Michiharu Kageyama, Keizo Fukushima, Tatsuya Togawa, Katsukuni Fujimoto, Mari Taki, Asako Nishimura, Yukako Ito, Nobuyuki Sugioka, Nobuhito Shibata & Kanji Takada. (2006) Relationship between Excretion Clearance of Rhodamine 123 and P-Glycoprotein (Pgp) Expression Induced by Representative Pgp Inducers. Biological and Pharmaceutical Bulletin 29:4, pages 779-784.
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Jing Wei Qi, Katsunori Nakamura, Shin Hosokawa, Yuko Okada, Ryuya Horiuchi & Koujirou Yamamoto. (2005) Time-Dependent Induction of Midazolam-1-hydroxylation Enzymes in Rats Treated with St. John's Wort. Biological and Pharmaceutical Bulletin 28:8, pages 1467-1471.
Crossref
Crossref
Kiyoyuki Kitaichi, Hironao Nakayama, Jun Ueyama, Masayuki Nadai, Kenji Baba, Kenji Takagi, Kenzo Takagi, Michio Ohta & Takaaki Hasegawa. (2004) Down-regulation of cytochrome P450 proteins and its activities by Shiga-like toxin II from Escherichia coli O157:H7. Biochemical Pharmacology 67:8, pages 1427-1435.
Crossref
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