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Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 11
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Research Article

Decreased activity of hepatic P-glycoprotein in the isolated perfused liver of the adjuvant arthritis rat

M. Achira Discovery Research Laboratory, Tanabe Seiyaku Co., Ltd, 2-2-50 Kawagishi Toda Saitama 335-8505, Japan
,
R. Totsuka Discovery Research Laboratory, Tanabe Seiyaku Co., Ltd, 2-2-50 Kawagishi Toda Saitama 335-8505, Japan
&
T. Kume Discovery Research Laboratory, Tanabe Seiyaku Co., Ltd, 2-2-50 Kawagishi Toda Saitama 335-8505, Japan
Pages 963-973 | Published online: 22 Sep 2008

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S. Uno, A. Fujii, H. Komura, A. Kawase & M. Iwaki. (2008) Prediction of metabolic clearance of diclofenac in adjuvant-induced arthritis rats using a substrate depletion assay. Xenobiotica 38:5, pages 482-495.
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Articles from other publishers (5)

Yi-jin Wu, Chun Wang & Wei Wei. (2018) The effects of DMARDs on the expression and function of P-gp, MRPs, BCRP in the treatment of autoimmune diseases. Biomedicine & Pharmacotherapy 105, pages 870-878.
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Misato Uraki, Atsushi Kawase, Hiroyuki Sayama, Yuka Matsushima & Masahiro Iwaki. (2017) Effects of Adjuvant-Induced Inflammation on Disposition of Diclofenac and Its Metabolites in Perfused Rat Liver. Journal of Pharmaceutical Sciences 106:4, pages 1175-1182.
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D. Kojovic & M. Piquette-Miller. 2017. Drug Metabolism in Diseases. Drug Metabolism in Diseases 59 89 .
Leos Fuksa, Eva Brcakova, Jolana Cermanova, Milos Hroch, Jaroslav Chladek, Gabriela Kolouchova, Jana Malakova, Jirina Martinkova, Frantisek Staud & Stanislav Micuda. (2008) Amiodarone modulates pharmacokinetics of low‐dose methotrexate in rats. Biopharmaceutics & Drug Disposition 29:5, pages 289-299.
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Yen Tong, Ruhong Zhang, Suong NT Ngo & Andrew K Davey. (2006) ALTERATION OF FEXOFENADINE DISPOSITION IN THE RAT ISOLATED PERFUSED LIVER FOLLOWING INJECTION OF BACTERIAL LIPOPOLYSACCHARIDE. Clinical and Experimental Pharmacology and Physiology 33:8, pages 685-689.
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