Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 9
83
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Use of a quantitative real-time reverse transcription-polymerase chain reaction method to study the induction of CYP1A, CYP2B and CYP4A forms in precision-cut rat liver slices

, , , , , , & show all
Pages 739-747 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Shuhua Deng, Chunfeng Wang, Wei Zhang, Wenchao Gao, Ali Fan, Qiuyang Zhang, Yongjie Zhang, Qingwang Liu, Ning Li, Qi Liu, Jie Zhao, Cuiyun Li, Xingyuan Wen, Di Zhao & Xijing Chen. (2014) Effect of triacontanol on the pharmacokinetics of docetaxel in rats associated with induction of cytochrome P450 3A1/2. Xenobiotica 44:7, pages 583-590.
Read now
Er-Jia Wang, George Mandakas, Jairam Palamanda, Xinjie Lin, Pramila Kumari, Inhou Chu, Anthony Soares, Roger J. Smith, Ronald D. Snyder & Yi-Zhong Gu. (2008) Temporal Evaluation of CYP mRNA in Mice Administered with Prototypical P450 Inducers: Comparison with Conventional Protein/Enzyme Methods. Drug and Chemical Toxicology 31:4, pages 501-513.
Read now
Inge AM de Graaf, Geny MM Groothuis & Peter Olinga. (2007) Precision-cut tissue slices as a tool to predict metabolism of novel drugs. Expert Opinion on Drug Metabolism & Toxicology 3:6, pages 879-898.
Read now
Z. Tong, A. Chandrasekaran, R. Jordan, V. Markiewicz, H. Li, Q. Xiang, L. Shen & J. Scatina. (2007) Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes. Xenobiotica 37:1, pages 1-18.
Read now
Rolf Gebhardt, Jan G. Hengstler, Dieter Müller, Reinhild Glöckner, Peter Buenning, Britta Laube, Eva Schmelzer, Martina Ullrich, Dietmar Utesch, Nicola Hewitt, Michael Ringel, Beate Reder Hilz, Augustinus Bader, Angelika Langsch, Thomas Koose, Hans-Jörg Burger, Jochen Maas & Franz Oesch. (2003) New Hepatocyte In Vitro Systems for Drug Metabolism: Metabolic Capacity and Recommendations for Application in Basic Research and Drug Development, Standard Operation Procedures. Drug Metabolism Reviews 35:2-3, pages 145-213.
Read now
C. Meredith, M. P. Scott, A. B. Renwick, R. J. Price & B. G. Lake. (2003) Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices. Xenobiotica 33:5, pages 511-527.
Read now

Articles from other publishers (12)

Yan Yu, Tian-Zhu Jia, Qian Cai, Ning Jiang, Ming-yue Ma, Dong-yu Min & Yuan Yuan. (2015) Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid. Journal of Ethnopharmacology 160, pages 211-218.
Crossref
Adriana R. Schultz Moreira, Rosa A. García-Fernández, Aranzazu Bocanegra, M. Teresa Méndez, Sara Bastida, Juana Benedí, M. Isabel Sánchez-Reus & Francisco J. Sánchez-Muniz. (2013) Effects of seaweed-restructured pork diets enriched or not with cholesterol on rat cholesterolaemia and liver damage. Food and Chemical Toxicology 56, pages 223-230.
Crossref
Tao Su, Chunqin Mao, Fangzhou Yin, Zhiling Yu, Ying Lin, Yu Song & Tulin Lu. (2013) Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats. Journal of Ethnopharmacology 146:3, pages 734-743.
Crossref
Alexander V. LyubimovCostas Ioannides & Brian G. Lake. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 26 .
Jason R. Catania, Barbara P. McGarrigle, Kate Rittenhouse-Olson & James R. Olson. (2007) Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium. Toxicology in Vitro 21:1, pages 109-115.
Crossref
Masamichi Yamashita. (2007) Peroxisome proliferator-activated receptor α-independent effects of peroxisome proliferators on cysteinyl leukotriene production in mast cells. European Journal of Pharmacology 556:1-3, pages 172-180.
Crossref
Sandra J. Baldwin, Jo L. Bramhall, Charlotte A. Ashby, Lin Yue, Paul R. Murdock, Steven R. Hood, Andrew D. Ayrton & Stephen E. Clarke. (2006) CYTOCHROME P450 GENE INDUCTION IN RATS EX VIVO ASSESSED BY QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTASE-POLYMERASE CHAIN REACTION (TAQMAN). Drug Metabolism and Disposition 34:6, pages 1063-1069.
Crossref
Marcella Martignoni, Ruben de Kanter, Pietro Grossi, Grazia Saturno, Elena Barbaria & Mario Monshouwer. (2006) An in vivo and in vitro comparison of CYP gene induction in mice using liver slices and quantitative RT-PCR. Toxicology in Vitro 20:1, pages 125-131.
Crossref
Xiaoming Cui, Ann Thomas, Yi Han, Jairam Palamanda, Diana Montgomery, Ronald E. White, Richard A. Morrison & K.-C. Cheng. (2005) Quantitative PCR assay for cytochromes P450 2B and 3A induction in rat precision-cut liver slices: Correlation study with induction in vivo. Journal of Pharmacological and Toxicological Methods 52:2, pages 234-243.
Crossref
Eric J. Semler, Perry A. Lancin, Anouska Dasgupta & Prabhas V. Moghe. (2005) Engineering hepatocellular morphogenesis and function via ligand-presenting hydrogels with graded mechanical compliance. Biotechnology and Bioengineering 89:3, pages 296-307.
Crossref
Marcella Martignoni, Ruben de Kanter, Pietro Grossi, Axel Mahnke, Grazia Saturno & Mario Monshouwer. (2004) An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR. Chemico-Biological Interactions 151:1, pages 1-11.
Crossref
Thomas A. Brieva & Prabhas V. Moghe. (2003) Exogenous cadherin microdisplay can interfere with endogenous signaling and reprogram gene expression in cultured hepatocytes. Biotechnology and Bioengineering 85:3, pages 283-292.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.