Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 11
Submit an article Journal homepage
135
Views
9
CrossRef citations to date
0
Altmetric
Research Article

In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone

Z. Yan Division of Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
,
G. W. Caldwell Division of Preclinical Development, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
,
W. N. Wu Division of Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
,
L. A. McKown Division of Preclinical Development, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
,
B. Rafferty Division of Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
,
W. Jones Division of Preclinical Development, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
&
J. A. Masucci Division of Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, Spring House, PA 19477, USA
 show all
Pages 949-962 | Published online: 22 Sep 2008

Citations (9)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

N. D. Forsberg, R. Rodriguez-Proteau, L. Ma, J. Morré, J. M. Christensen, C. S. Maier, J. J. Jenkins & K. A. Anderson. (2011) Organophosphorus pesticide degradation product in vitro metabolic stability and time-course uptake and elimination in rats following oral and intravenous dosing. Xenobiotica 41:5, pages 422-429.
Read now

Articles from other publishers (8)

Jelena Z. Penjišević, Vladimir B. Šukalović, Deana B. Andrić, Relja Suručić & Sladjana V. Kostić-Rajačić. (2022) The Therapeutic Potential of 2-{[4-(2-methoxyphenyl)piperazin-1-yl]alkyl}-1H-benzo[d]imidazoles as Ligands for Alpha1-Adrenergic Receptor - Comparative In Silico and In Vitro Study. Applied Biochemistry and Biotechnology 194:8, pages 3749-3764.
Crossref
Zhengyin Yan & Gary W. Caldwell. 2013. Pharmacogenomics. Pharmacogenomics 251 261 .
Markus R. Meyer & Hans H. Maurer. 2012. Metabolism of Drugs and Other Xenobiotics. Metabolism of Drugs and Other Xenobiotics 429 463 .
Simon Elliott. (2011) Current awareness of piperazines: pharmacology and toxicology. Drug Testing and Analysis 3:7-8, pages 430-438.
Crossref
Shayne Cox GadEugene G. Hrycay & Stelvio M. Bandiera. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Bo Wen, Li Ma, A. David Rodrigues & Mingshe Zhu. (2008) Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m -Chlorophenylpiperazine . Drug Metabolism and Disposition 36:5, pages 841-850.
Crossref
Zhengyin Yan, Jian Li, Norman Huebert, Gary W. Caldwell, Yanming Du & Hua Zhong. (2005) DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES. Drug Metabolism and Disposition 33:6, pages 706-713.
Crossref
Z. Yan & G. W. Caldwell. (2003) Metabolic assessment in liver microsomes by co-activating cytochrome P450s and UDP-glycosyltransferases. European Journal of Drug Metabolism and Pharmacokinetics 28:3, pages 223-232.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.