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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 7
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Research Article

In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes

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Pages 717-729 | Published online: 02 Jul 2010

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Yuka Ono, Souta Sugiyama, Mayu Matsushita, Takio Kitazawa, Tomoko Amano, Yasuhiro Uno, Shinichi Ikushiro & Hiroki Teraoka. (2019) Limited expression of functional cytochrome p450 2c subtypes in the liver and small intestine of domestic cats. Xenobiotica 49:6, pages 627-635.
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Toshiro Niwa, Norie Murayama, Yurie Imagawa & Hiroshi Yamazaki. (2015) Regioselective hydroxylation of steroid hormones by human cytochromes P450. Drug Metabolism Reviews 47:2, pages 89-110.
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Abidemi J. Akindele, Erika A. Eksioglu, Jason C. Kwan, Olufunmilayo O. Adeyemi, Chen Liu, Hendrik Luesch & Margaret O. James. (2011) Biological effects of Byrsocarpus coccineus in vitro. Pharmaceutical Biology 49:2, pages 152-160.
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N. Araki, S. Tsuruoka, N. Wang, G. Hasegawa, H. Yanagihara, H. Ando, T. Omasa, S. Enosawa, H. Nagai & A. Fujimura. (2008) Human CYP3A4-introduced HepG2 cells: screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity. Xenobiotica 38:11, pages 1355-1364.
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J. P. Chovan, S. C. Ring, E. Yu & J. P. Baldino. (2007) Cytochrome P450 probe substrate metabolism kinetics in Sprague Dawley rats. Xenobiotica 37:5, pages 459-473.
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Z. Zhang, Y. Li, M. Shou, Y. Zhang, J. S. Ngui, R. A. Stearns, D. C. Evans, T. A. Baillie & W. Tang. (2004) Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4. Xenobiotica 34:5, pages 473-486.
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Toshiro Niwa, Manami Toyota, Hinako Kawasaki, Risa Ishii & Shoko Sasaki. (2021) Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies. Biological and Pharmaceutical Bulletin 44:4, pages 579-584.
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Matthew G. McDonald, Dan-Dan Tian, Kenneth E. Thummel, Mary F. Paine & Allan E. Rettie. (2020) Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects. Drug Metabolism and Disposition 48:10, pages 1018-1027.
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Jiuying Tian, Mingjuan Huang, Yanting Yang, Dongyue Wang & Jusheng Lu. (2019) Photoelectrochemically driven bioconversion and determination of nifedipine based on a double photoelectrode system. Biosensors and Bioelectronics 135, pages 160-165.
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Toshiro Niwa, Kazushi Okada, Toyoko Hiroi, Susumu Imaoka, Shizuo Narimatsu & Yoshihiko Funae. (2008) Effect of Psychotropic Drugs on the 21-Hydroxylation of Neurosteroids, Progesterone and Allopregnanolone, Catalyzed by Rat CYP2D4 and Human CYP2D6 in the Brain. Biological and Pharmaceutical Bulletin 31:3, pages 348-351.
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Toshiro NIWASachiko YAMAMOTOMiho SAITOToshifumi SHIRAGAAkira TAKAGI. (2007) Effect of Cyclosporine and Tacrolimus on Cytochrome P450 Activities in Human Liver Microsomes. YAKUGAKU ZASSHI 127:1, pages 209-216.
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Toshiro NiwaSachiko YamamotoMiho SaitoNaoto KobayashiKaoru IkedaYasuo NodaAkira Takagi. (2006) Effects of Serotonin-3 Receptor Antagonists on Cytochrome P450 Activities in Human Liver Microsomes. Biological and Pharmaceutical Bulletin 29:9, pages 1931-1935.
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Toshiro NIWAToshifumi SHIRAGAAkira TAKAGI. (2005) Drug-Drug Interaction of Antifungal Drugs抗真菌剤の薬物相互作用—薬物代謝酵素に及ぼす影響—. YAKUGAKU ZASSHI 125:10, pages 795-805.
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Toshiro NiwaSachiko InoueToshifumi ShiragaAkira Takagi. (2005) No Inhibition of Cytochrome P450 Activities in Human Liver Microsomes by Sulpiride, an Antipsychotic Drug. Biological and Pharmaceutical Bulletin 28:1, pages 188-191.
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Toshiro NiwaToshifumi ShiragaAkira Takagi. (2005) Effect of Antifungal Drugs on Cytochrome P450 (CYP) 2C9, CYP2C19, and CYP3A4 Activities in Human Liver Microsomes. Biological and Pharmaceutical Bulletin 28:9, pages 1805-1808.
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